The role of oxytocin on self-serving lying

Abstract

Introduction: The effects of intranasal administration of the neuropeptide oxytocin on social cognition and behavior are highly specific. Potentially situational and personal variables influence these effects. The aim of the present study was to investigate effects of oxytocin administration on self-serving lying, including situational effects. Methods: A total of 161 adult males participated in a randomized double-blind placebo-controlled between-subject intranasal oxytocin administration (24 international units) study. Self-serving lying was assessed using three subsequent rounds of the die-in-a-cup paradigm, in which different degrees of lying can be implemented by the participants that can be determined on group level. Results: Oxytocin administration seemed to promote self-serving lying, particularly in the third (last) round and only to a certain degree (not to the maximum possible). Conclusions: Our findings demonstrate that oxytocin administration can promote self-serving lying when given repeated opportunities to lie. Moreover, exploratory results presented in the Supplementary Material indicate that the sensitivity to the effects of intranasal oxytocin in this domain might be moderated by individual differences in the oxytocin receptor gene.