File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Roles and Molecular Mechanisms of Biomarkers in Hepatocellular Carcinoma with Microvascular Invasion: A Review.

TitleRoles and Molecular Mechanisms of Biomarkers in Hepatocellular Carcinoma with Microvascular Invasion: A Review.
Authors
KeywordsBiomarkers
Hepatocellular carcinoma
Microvascular invasion
Molecular mechanism
Progress
Issue Date28-Oct-2023
PublisherXIA & HE Publishing Inc.
Citation
Journal of Clinical and Translational Hepatology, 2023, v. 11, n. 5, p. 1170-1183 How to Cite?
AbstractHepatocellular carcinoma (HCC) being a leading cause of cancer-related death, has high associated mortality and recurrence rates. It has been of great necessity and urgency to find effective HCC diagnosis and treatment measures. Studies have shown that microvascular invasion (MVI) is an independent risk factor for poor prognosis after hepatectomy. The abnormal expression of biomacromolecules such as circ-RNAs, lncRNAs, STIP1, and PD-L1 in HCC patients is strongly correlated with MVI. Deregulation of several markers mentioned in this review affects the proliferation, invasion, metastasis, EMT, and anti-apoptotic processes of HCC cells through multiple complex mechanisms. Therefore, these biomarkers may have an important clinical role and serve as promising interventional targets for HCC. In this review, we provide a comprehensive overview on the functions and regulatory mechanisms of MVI-related biomarkers in HCC.
Persistent Identifierhttp://hdl.handle.net/10722/331271
ISSN
2023 Impact Factor: 3.1
2023 SCImago Journal Rankings: 0.988
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorZhao, X-
dc.contributor.authorWang, Y-
dc.contributor.authorXia, H-
dc.contributor.authorLiu, S-
dc.contributor.authorHuang, Z-
dc.contributor.authorHe, R-
dc.contributor.authorYu, L-
dc.contributor.authorMeng, N-
dc.contributor.authorWang, H-
dc.contributor.authorYou, J-
dc.contributor.authorLi, J-
dc.contributor.authorYam, JWP-
dc.contributor.authorXu, Y-
dc.contributor.authorCui, Y-
dc.date.accessioned2023-09-21T06:54:13Z-
dc.date.available2023-09-21T06:54:13Z-
dc.date.issued2023-10-28-
dc.identifier.citationJournal of Clinical and Translational Hepatology, 2023, v. 11, n. 5, p. 1170-1183-
dc.identifier.issn2225-0719-
dc.identifier.urihttp://hdl.handle.net/10722/331271-
dc.description.abstractHepatocellular carcinoma (HCC) being a leading cause of cancer-related death, has high associated mortality and recurrence rates. It has been of great necessity and urgency to find effective HCC diagnosis and treatment measures. Studies have shown that microvascular invasion (MVI) is an independent risk factor for poor prognosis after hepatectomy. The abnormal expression of biomacromolecules such as circ-RNAs, lncRNAs, STIP1, and PD-L1 in HCC patients is strongly correlated with MVI. Deregulation of several markers mentioned in this review affects the proliferation, invasion, metastasis, EMT, and anti-apoptotic processes of HCC cells through multiple complex mechanisms. Therefore, these biomarkers may have an important clinical role and serve as promising interventional targets for HCC. In this review, we provide a comprehensive overview on the functions and regulatory mechanisms of MVI-related biomarkers in HCC.-
dc.languageeng-
dc.publisherXIA & HE Publishing Inc.-
dc.relation.ispartofJournal of Clinical and Translational Hepatology-
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.-
dc.subjectBiomarkers-
dc.subjectHepatocellular carcinoma-
dc.subjectMicrovascular invasion-
dc.subjectMolecular mechanism-
dc.subjectProgress-
dc.titleRoles and Molecular Mechanisms of Biomarkers in Hepatocellular Carcinoma with Microvascular Invasion: A Review.-
dc.typeArticle-
dc.identifier.doi10.14218/JCTH.2022.00013S-
dc.identifier.pmid37577231-
dc.identifier.scopuseid_2-s2.0-85167456601-
dc.identifier.volume11-
dc.identifier.issue5-
dc.identifier.spage1170-
dc.identifier.epage1183-
dc.identifier.isiWOS:000994866100001-
dc.identifier.issnl2225-0719-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats