Impact of Hysteroscopic Polypectomy on Pregnancy Outcomes of in Vitro Fertilization

Abstract

OBJECTIVE: Endometrial polyps are commonly found in infertile women, but the impact of hysteroscopic polypectomy on in vitro fertilization (IVF) pregnancy outcomes was unclear. We aim to compare IVF pregnancy outcomes following hysteroscopic polypectomy to those with a normal uterine cavity.STUDY DESIGN: Retrospective chart review of all women undergoing saline sonohysterogram prior to first IVF cycle from January 2012 to December 2013, in a university affiliated hospital.RESULTS: A total of 715 women had saline sonohysterogram during the study period, and endometrial polyps were identified in 65 with confirmation by hysteroscopy; 639 women had a normal uterine cavity. The positive predictive value of saline sonohysterogram was 97.0%, and the incidence was 9.1%. There were no differences in demographic parameters between women having hysteroscopic polypectomy and those with a normal uterine cavity. Clinical pregnancy rate (29.2% vs. 33.0% in women with hysteroscopic polypectomy and normal uterine cavity, respectively, p =0.535) and live birth rate (24.6% vs. 24.6% in women with hysteroscopic polypectomy and normal uterine cavity, respectively, p = 0.841) were similar.CONCLUSION: Women having hysteroscopic polypectomy achieved similar IVF pregnancy outcomes when compared to those with a normal uterine cavity confirmed by saline sonohysterogram.