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Article: Non-alcoholic fatty liver disease: the pathologist’s perspective

TitleNon-alcoholic fatty liver disease: the pathologist’s perspective
Authors
KeywordsBiopsy
Diagnosis
Histology
Non-alcoholic fatty liver disease
Prognosis
Issue Date28-Feb-2023
PublisherKorean Association for the Study of the Liver
Citation
Clinical and Molecular Hepatology, 2023, v. 29, p. S302-S318 How to Cite?
Abstract

Non-alcoholic fatty liver disease (NAFLD) is a spectrum of diseases characterized by fatty accumulation in hepatocytes, ranging from steatosis, non-alcoholic steatohepatitis, to cirrhosis. While histopathological evaluation of liver biopsies plays a central role in the diagnosis of NAFLD, limitations such as the problem of interobserver variability still exist and active research is underway to improve the diagnostic utility of liver biopsies. In this article, we provide a comprehensive overview of the histopathological features of NAFLD, the current grading and staging systems, and discuss the present and future roles of liver biopsies in the diagnosis and prognostication of NAFLD.


Persistent Identifierhttp://hdl.handle.net/10722/331977
ISSN
2023 Impact Factor: 14.0
2023 SCImago Journal Rankings: 3.128
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorLeow, Wei-Qiang-
dc.contributor.authorChan, Anthony Wing-Hung-
dc.contributor.authorMendoza, Paulo Giovanni L-
dc.contributor.authorLo, Regina-
dc.contributor.authorYap, Kihan-
dc.contributor.authorKim, Haeryoung-
dc.date.accessioned2023-09-28T05:00:00Z-
dc.date.available2023-09-28T05:00:00Z-
dc.date.issued2023-02-28-
dc.identifier.citationClinical and Molecular Hepatology, 2023, v. 29, p. S302-S318-
dc.identifier.issn2287-2728-
dc.identifier.urihttp://hdl.handle.net/10722/331977-
dc.description.abstract<p>Non-alcoholic fatty liver disease (NAFLD) is a spectrum of diseases characterized by fatty accumulation in hepatocytes, ranging from steatosis, non-alcoholic steatohepatitis, to cirrhosis. While histopathological evaluation of liver biopsies plays a central role in the diagnosis of NAFLD, limitations such as the problem of interobserver variability still exist and active research is underway to improve the diagnostic utility of liver biopsies. In this article, we provide a comprehensive overview of the histopathological features of NAFLD, the current grading and staging systems, and discuss the present and future roles of liver biopsies in the diagnosis and prognostication of NAFLD.<br></p>-
dc.languageeng-
dc.publisherKorean Association for the Study of the Liver-
dc.relation.ispartofClinical and Molecular Hepatology-
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.-
dc.subjectBiopsy-
dc.subjectDiagnosis-
dc.subjectHistology-
dc.subjectNon-alcoholic fatty liver disease-
dc.subjectPrognosis-
dc.titleNon-alcoholic fatty liver disease: the pathologist’s perspective-
dc.typeArticle-
dc.identifier.doi10.3350/cmh.2022.0329-
dc.identifier.scopuseid_2-s2.0-85150197827-
dc.identifier.volume29-
dc.identifier.spageS302-
dc.identifier.epageS318-
dc.identifier.isiWOS:000941446200028-
dc.identifier.issnl2287-2728-

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