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Article: Stimulated release of size-selected cargos in succession from mesoporous silica nanoparticles

TitleStimulated release of size-selected cargos in succession from mesoporous silica nanoparticles
Authors
Wang, ChengLi, ZongxiCao, DennisZhao, Yan LiGaines, Justin W.Bozdemir, O. AltanAmbrogio, Michael W.Frasconi, MarcoBotros, Youssry Y.Zink, Jeffrey I.Stoddart, J. Fraser
Keywordsβ-cyclodextrins
cargo release
drug delivery
nanostructures
nanotechnology
Issue Date2012
Citation
Angewandte Chemie - International Edition, 2012, v. 51, n. 22, p. 5460-5465 How to Cite?
DOI: http://dx.doi.org/10.1002/anie.201107960
AbstractTwo birds with one stone: Covalent attachment of β-cyclodextrin rings (yellow; see figure) to mesoporous silica nanoparticles (MSNs) results in a dual-cargo release system into which differently sized cargos (blue and red spheres) can be loaded and then released in sequence when triggered by two different stimuli. The smaller molecules are released by lowering the pH value and the larger ones released after cleavage of the cyclodextrins from the MSN surface. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Persistent Identifierhttp://hdl.handle.net/10722/332977
ISSN
1433-7851
2023 Impact Factor: 16.1
2023 SCImago Journal Rankings: 5.300
ISI Accession Number ID
WOS:000304345800037

 

DC FieldValueLanguage
dc.contributor.authorWang, Cheng-
dc.contributor.authorLi, Zongxi-
dc.contributor.authorCao, Dennis-
dc.contributor.authorZhao, Yan Li-
dc.contributor.authorGaines, Justin W.-
dc.contributor.authorBozdemir, O. Altan-
dc.contributor.authorAmbrogio, Michael W.-
dc.contributor.authorFrasconi, Marco-
dc.contributor.authorBotros, Youssry Y.-
dc.contributor.authorZink, Jeffrey I.-
dc.contributor.authorStoddart, J. Fraser-
dc.date.accessioned2023-10-06T05:15:47Z-
dc.date.available2023-10-06T05:15:47Z-
dc.date.issued2012-
dc.identifier.citationAngewandte Chemie - International Edition, 2012, v. 51, n. 22, p. 5460-5465-
dc.identifier.issn1433-7851-
dc.identifier.urihttp://hdl.handle.net/10722/332977-
dc.description.abstractTwo birds with one stone: Covalent attachment of β-cyclodextrin rings (yellow; see figure) to mesoporous silica nanoparticles (MSNs) results in a dual-cargo release system into which differently sized cargos (blue and red spheres) can be loaded and then released in sequence when triggered by two different stimuli. The smaller molecules are released by lowering the pH value and the larger ones released after cleavage of the cyclodextrins from the MSN surface. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.-
dc.languageeng-
dc.relation.ispartofAngewandte Chemie - International Edition-
dc.subjectβ-cyclodextrins-
dc.subjectcargo release-
dc.subjectdrug delivery-
dc.subjectnanostructures-
dc.subjectnanotechnology-
dc.titleStimulated release of size-selected cargos in succession from mesoporous silica nanoparticles-
dc.typeArticle-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1002/anie.201107960-
dc.identifier.pmid22505218-
dc.identifier.scopuseid_2-s2.0-84861498510-
dc.identifier.volume51-
dc.identifier.issue22-
dc.identifier.spage5460-
dc.identifier.epage5465-
dc.identifier.eissn1521-3773-
dc.identifier.isiWOS:000304345800037-

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