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Article: Esterase- and pH-responsive poly(β-amino ester)-capped mesoporous silica nanoparticles for drug delivery

TitleEsterase- and pH-responsive poly(β-amino ester)-capped mesoporous silica nanoparticles for drug delivery
Authors
Issue Date2015
Citation
Nanoscale, 2015, v. 7, n. 16, p. 7178-7183 How to Cite?
AbstractGating of mesoporous silica nanoparticles (MSNs) with the stimuli-responsive poly(β-amino ester) has been achieved. This hybrid nanocarrier releases doxorubicin (DOX) under acidic conditions or in the presence of porcine liver esterase. The DOX loaded poly(β-amino ester)-capped MSNs reduce cell viability when tested on MDA-MB-231 human breast cancer cells.
Persistent Identifierhttp://hdl.handle.net/10722/333113
ISSN
2023 Impact Factor: 5.8
2023 SCImago Journal Rankings: 1.416
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorFernando, Isurika R.-
dc.contributor.authorFerris, Daniel P.-
dc.contributor.authorFrasconi, Marco-
dc.contributor.authorMalin, Dmitry-
dc.contributor.authorStrekalova, Elena-
dc.contributor.authorYilmaz, M. Deniz-
dc.contributor.authorAmbrogio, Michael W.-
dc.contributor.authorAlgaradah, Mohammed M.-
dc.contributor.authorHong, Michael P.-
dc.contributor.authorChen, Xinqi-
dc.contributor.authorNassar, Majed S.-
dc.contributor.authorBotros, Youssry Y.-
dc.contributor.authorCryns, Vincent L.-
dc.contributor.authorStoddart, J. Fraser-
dc.date.accessioned2023-10-06T05:16:50Z-
dc.date.available2023-10-06T05:16:50Z-
dc.date.issued2015-
dc.identifier.citationNanoscale, 2015, v. 7, n. 16, p. 7178-7183-
dc.identifier.issn2040-3364-
dc.identifier.urihttp://hdl.handle.net/10722/333113-
dc.description.abstractGating of mesoporous silica nanoparticles (MSNs) with the stimuli-responsive poly(β-amino ester) has been achieved. This hybrid nanocarrier releases doxorubicin (DOX) under acidic conditions or in the presence of porcine liver esterase. The DOX loaded poly(β-amino ester)-capped MSNs reduce cell viability when tested on MDA-MB-231 human breast cancer cells.-
dc.languageeng-
dc.relation.ispartofNanoscale-
dc.titleEsterase- and pH-responsive poly(β-amino ester)-capped mesoporous silica nanoparticles for drug delivery-
dc.typeArticle-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1039/c4nr07443b-
dc.identifier.pmid25820516-
dc.identifier.scopuseid_2-s2.0-84927946170-
dc.identifier.volume7-
dc.identifier.issue16-
dc.identifier.spage7178-
dc.identifier.epage7183-
dc.identifier.eissn2040-3372-
dc.identifier.isiWOS:000352905700032-

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