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- Publisher Website: 10.1002/anie.200604295
- Scopus: eid_2-s2.0-34247582332
- PMID: 17290476
- WOS: WOS:000245071000016
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Article: siRNA delivery into human T cells and primary cells with carbon-nanotube transporters
Title | siRNA delivery into human T cells and primary cells with carbon-nanotube transporters |
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Authors | |
Keywords | Carbon nanotubes Drug delivery Nanobiotechnology RNA interference T cells |
Issue Date | 2007 |
Citation | Angewandte Chemie - International Edition, 2007, v. 46, n. 12, p. 2023-2027 How to Cite? |
Abstract | Special delivery: Functionalized single-walled nanotubes (SWNT) can be used as molecular transporters to shuttle short interfering RNA (siRNA) into human T cells and primary cells and silence the expression of HIV-specific cell-surface receptors and coreceptors (see picture; scale bars 40 μm). This silencing effect, known to block HIV viral entry and reduce infection, is superior to that observed with conventional liposome-based nonviral delivery agents. (Figure Presented). © 2007 Wiley-VCH Verlag GmbH & Co. KGaA. |
Persistent Identifier | http://hdl.handle.net/10722/334143 |
ISSN | 2023 Impact Factor: 16.1 2023 SCImago Journal Rankings: 5.300 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Liu, Zhuang | - |
dc.contributor.author | Winters, Mark | - |
dc.contributor.author | Holodniy, Mark | - |
dc.contributor.author | Dai, Hongjie | - |
dc.date.accessioned | 2023-10-20T06:46:02Z | - |
dc.date.available | 2023-10-20T06:46:02Z | - |
dc.date.issued | 2007 | - |
dc.identifier.citation | Angewandte Chemie - International Edition, 2007, v. 46, n. 12, p. 2023-2027 | - |
dc.identifier.issn | 1433-7851 | - |
dc.identifier.uri | http://hdl.handle.net/10722/334143 | - |
dc.description.abstract | Special delivery: Functionalized single-walled nanotubes (SWNT) can be used as molecular transporters to shuttle short interfering RNA (siRNA) into human T cells and primary cells and silence the expression of HIV-specific cell-surface receptors and coreceptors (see picture; scale bars 40 μm). This silencing effect, known to block HIV viral entry and reduce infection, is superior to that observed with conventional liposome-based nonviral delivery agents. (Figure Presented). © 2007 Wiley-VCH Verlag GmbH & Co. KGaA. | - |
dc.language | eng | - |
dc.relation.ispartof | Angewandte Chemie - International Edition | - |
dc.subject | Carbon nanotubes | - |
dc.subject | Drug delivery | - |
dc.subject | Nanobiotechnology | - |
dc.subject | RNA interference | - |
dc.subject | T cells | - |
dc.title | siRNA delivery into human T cells and primary cells with carbon-nanotube transporters | - |
dc.type | Article | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1002/anie.200604295 | - |
dc.identifier.pmid | 17290476 | - |
dc.identifier.scopus | eid_2-s2.0-34247582332 | - |
dc.identifier.volume | 46 | - |
dc.identifier.issue | 12 | - |
dc.identifier.spage | 2023 | - |
dc.identifier.epage | 2027 | - |
dc.identifier.isi | WOS:000245071000016 | - |