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Article: Validation of IgG, IgM multiplex plasmonic gold platform in French clinical cohorts for the serodiagnosis and follow-up of Toxoplasma gondii infection

TitleValidation of IgG, IgM multiplex plasmonic gold platform in French clinical cohorts for the serodiagnosis and follow-up of Toxoplasma gondii infection
Authors
KeywordsAdults
Multiplex serology
Newborns
Plasmonic gold pGOLD
Seroconversion
Toxoplasma gondii
Issue Date2017
Citation
Diagnostic Microbiology and Infectious Disease, 2017, v. 87, n. 3, p. 213-218 How to Cite?
AbstractWe report the use of the multiplexed T. gondii IgG, IgM test on plasmonic gold (pGOLD) platform in the setting of T. gondii infection by analyzing 244 sera from Nice, France (seroconversion, chronically infected, non-infected and newborns serum samples). Results were compared with commercial tests for the detection of IgG and IgM and their overall clinical final interpretation of a complete serological profile. The IgG and IgM test results on the platform were in agreement in, respectively, 95% and 93% with the commercial kits. When comparing with the overall clinical interpretation of the serological profile, the agreement reached 99.5% and 97.7% for IgG and IgM, respectively. This innovative pGOLD platform allows detection of both IgG and IgM simultaneously with only ~1 microliter of serum. The multiplexed IgG/IgM test on pGOLD platform is a strong candidate for its use in the massive screening programs for toxoplasmosis during pregnancy.
Persistent Identifierhttp://hdl.handle.net/10722/334459
ISSN
2023 Impact Factor: 2.1
2023 SCImago Journal Rankings: 0.626
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorPomares, Christelle-
dc.contributor.authorZhang, Bo-
dc.contributor.authorArulkumar, Shylaja-
dc.contributor.authorGonfrier, Geraldine-
dc.contributor.authorMarty, Pierre-
dc.contributor.authorZhao, Su-
dc.contributor.authorCheng, Steven-
dc.contributor.authorTang, Meijie-
dc.contributor.authorDai, Hongjie-
dc.contributor.authorMontoya, Jose G.-
dc.date.accessioned2023-10-20T06:48:17Z-
dc.date.available2023-10-20T06:48:17Z-
dc.date.issued2017-
dc.identifier.citationDiagnostic Microbiology and Infectious Disease, 2017, v. 87, n. 3, p. 213-218-
dc.identifier.issn0732-8893-
dc.identifier.urihttp://hdl.handle.net/10722/334459-
dc.description.abstractWe report the use of the multiplexed T. gondii IgG, IgM test on plasmonic gold (pGOLD) platform in the setting of T. gondii infection by analyzing 244 sera from Nice, France (seroconversion, chronically infected, non-infected and newborns serum samples). Results were compared with commercial tests for the detection of IgG and IgM and their overall clinical final interpretation of a complete serological profile. The IgG and IgM test results on the platform were in agreement in, respectively, 95% and 93% with the commercial kits. When comparing with the overall clinical interpretation of the serological profile, the agreement reached 99.5% and 97.7% for IgG and IgM, respectively. This innovative pGOLD platform allows detection of both IgG and IgM simultaneously with only ~1 microliter of serum. The multiplexed IgG/IgM test on pGOLD platform is a strong candidate for its use in the massive screening programs for toxoplasmosis during pregnancy.-
dc.languageeng-
dc.relation.ispartofDiagnostic Microbiology and Infectious Disease-
dc.subjectAdults-
dc.subjectMultiplex serology-
dc.subjectNewborns-
dc.subjectPlasmonic gold pGOLD-
dc.subjectSeroconversion-
dc.subjectToxoplasma gondii-
dc.titleValidation of IgG, IgM multiplex plasmonic gold platform in French clinical cohorts for the serodiagnosis and follow-up of Toxoplasma gondii infection-
dc.typeArticle-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.diagmicrobio.2016.09.001-
dc.identifier.pmid28040304-
dc.identifier.scopuseid_2-s2.0-85009384602-
dc.identifier.volume87-
dc.identifier.issue3-
dc.identifier.spage213-
dc.identifier.epage218-
dc.identifier.eissn1879-0070-
dc.identifier.isiWOS:000394407700004-

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