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Article: Diagnosis of Zika virus infection on a nanotechnology platform

TitleDiagnosis of Zika virus infection on a nanotechnology platform
Authors
Issue Date2017
Citation
Nature Medicine, 2017, v. 23, n. 5, p. 548-550 How to Cite?
AbstractWe developed a multiplexed assay on a plasmonic-gold platform for measuring IgG and IgA antibodies and IgG avidity against both Zika virus (ZIKV) and dengue virus (DENV) infections. In contrast to IgM cross-reactivity, IgG and IgA antibodies against ZIKV nonstructural protein 1 (NS1) antigen were specific to ZIKV infection, and IgG avidity revealed recent ZIKV infection and past DENV-2 infection in patients in dengue-endemic regions. This assay could enable specific diagnosis of ZIKV infection over other flaviviral infections.
Persistent Identifierhttp://hdl.handle.net/10722/334468
ISSN
2023 Impact Factor: 58.7
2023 SCImago Journal Rankings: 19.045
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorZhang, Bo-
dc.contributor.authorPinsky, Benjamin A.-
dc.contributor.authorAnanta, Jeyarama S.-
dc.contributor.authorZhao, Su-
dc.contributor.authorArulkumar, Shylaja-
dc.contributor.authorWan, Hao-
dc.contributor.authorSahoo, Malaya K.-
dc.contributor.authorAbeynayake, Janaki-
dc.contributor.authorWaggoner, Jesse J.-
dc.contributor.authorHopes, Clay-
dc.contributor.authorTang, Meijie-
dc.contributor.authorDai, Hongjie-
dc.date.accessioned2023-10-20T06:48:21Z-
dc.date.available2023-10-20T06:48:21Z-
dc.date.issued2017-
dc.identifier.citationNature Medicine, 2017, v. 23, n. 5, p. 548-550-
dc.identifier.issn1078-8956-
dc.identifier.urihttp://hdl.handle.net/10722/334468-
dc.description.abstractWe developed a multiplexed assay on a plasmonic-gold platform for measuring IgG and IgA antibodies and IgG avidity against both Zika virus (ZIKV) and dengue virus (DENV) infections. In contrast to IgM cross-reactivity, IgG and IgA antibodies against ZIKV nonstructural protein 1 (NS1) antigen were specific to ZIKV infection, and IgG avidity revealed recent ZIKV infection and past DENV-2 infection in patients in dengue-endemic regions. This assay could enable specific diagnosis of ZIKV infection over other flaviviral infections.-
dc.languageeng-
dc.relation.ispartofNature Medicine-
dc.titleDiagnosis of Zika virus infection on a nanotechnology platform-
dc.typeArticle-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1038/nm.4302-
dc.identifier.pmid28263312-
dc.identifier.scopuseid_2-s2.0-85014540313-
dc.identifier.volume23-
dc.identifier.issue5-
dc.identifier.spage548-
dc.identifier.epage550-
dc.identifier.eissn1546-170X-
dc.identifier.isiWOS:000400650700009-

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