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Article: The Role of ARV Associated Adverse Drug Reactions in Influencing Adherence Among HIV-Infected Individuals: A Systematic Review and Qualitative Meta-Synthesis

TitleThe Role of ARV Associated Adverse Drug Reactions in Influencing Adherence Among HIV-Infected Individuals: A Systematic Review and Qualitative Meta-Synthesis
Authors
KeywordsAdherence
Adverse drug reaction
Antiretroviral
HIV
Qualitative meta-synthesis
Issue Date2017
Citation
AIDS and Behavior, 2017, v. 21, n. 2, p. 341-351 How to Cite?
AbstractPoor adherence remains a major barrier to achieving the clinical and public health benefits of antiretroviral drugs (ARVs). A systematic review and qualitative meta-synthesis was conduct to evaluate how ARV adverse drug reactions may influence ARV adherence. Thirty-nine articles were identified, and 33 reported that ARV adverse drug reactions decreased adherence and six studies found no influence. Visually noticeable adverse drug reactions and psychological adverse reactions were reported as more likely to cause non-adherence compared to other adverse drug reactions. Six studies reported a range of adverse reactions associated with EFV-containing regimens contributing to decreased adherence. Informing HIV-infected individuals about ARV adverse drug reactions prior to initiation, counselling about coping mechanisms, and experiencing the effectiveness of ARVs on wellbeing may improve ARV adherence.
Persistent Identifierhttp://hdl.handle.net/10722/336692
ISSN
2023 Impact Factor: 2.7
2023 SCImago Journal Rankings: 1.440
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorLi, Haochu-
dc.contributor.authorMarley, Gifty-
dc.contributor.authorMa, Wei-
dc.contributor.authorWei, Chongyi-
dc.contributor.authorLackey, Mellanye-
dc.contributor.authorMa, Qingyan-
dc.contributor.authorRenaud, Françoise-
dc.contributor.authorVitoria, Marco-
dc.contributor.authorBeanland, Rachel-
dc.contributor.authorDoherty, Meg-
dc.contributor.authorTucker, Joseph D.-
dc.date.accessioned2024-02-29T06:55:51Z-
dc.date.available2024-02-29T06:55:51Z-
dc.date.issued2017-
dc.identifier.citationAIDS and Behavior, 2017, v. 21, n. 2, p. 341-351-
dc.identifier.issn1090-7165-
dc.identifier.urihttp://hdl.handle.net/10722/336692-
dc.description.abstractPoor adherence remains a major barrier to achieving the clinical and public health benefits of antiretroviral drugs (ARVs). A systematic review and qualitative meta-synthesis was conduct to evaluate how ARV adverse drug reactions may influence ARV adherence. Thirty-nine articles were identified, and 33 reported that ARV adverse drug reactions decreased adherence and six studies found no influence. Visually noticeable adverse drug reactions and psychological adverse reactions were reported as more likely to cause non-adherence compared to other adverse drug reactions. Six studies reported a range of adverse reactions associated with EFV-containing regimens contributing to decreased adherence. Informing HIV-infected individuals about ARV adverse drug reactions prior to initiation, counselling about coping mechanisms, and experiencing the effectiveness of ARVs on wellbeing may improve ARV adherence.-
dc.languageeng-
dc.relation.ispartofAIDS and Behavior-
dc.subjectAdherence-
dc.subjectAdverse drug reaction-
dc.subjectAntiretroviral-
dc.subjectHIV-
dc.subjectQualitative meta-synthesis-
dc.titleThe Role of ARV Associated Adverse Drug Reactions in Influencing Adherence Among HIV-Infected Individuals: A Systematic Review and Qualitative Meta-Synthesis-
dc.typeArticle-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1007/s10461-016-1545-0-
dc.identifier.pmid27613645-
dc.identifier.scopuseid_2-s2.0-84986243900-
dc.identifier.volume21-
dc.identifier.issue2-
dc.identifier.spage341-
dc.identifier.epage351-
dc.identifier.eissn1573-3254-
dc.identifier.isiWOS:000394150800003-

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