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Article: Case report: Coronavirus Disease 2019 (COVID-19) modified RNA vaccination-induced Adult-Onset Still's Disease with fulminant myocarditis as initial presentation

TitleCase report: Coronavirus Disease 2019 (COVID-19) modified RNA vaccination-induced Adult-Onset Still's Disease with fulminant myocarditis as initial presentation
Authors
Zhou, MiWong, Chun KaYeung, Wan Yin WinnieSiu, Chung WahYin, Lixue
KeywordsAdult-Onset Still's Disease (AOSD)
autoimmune disease
mRNA vaccine
myocarditis
vaccine
Issue Date15-Mar-2023
PublisherFrontiers Media
Citation
Frontiers in Cardiovascular Medicine, 2023, v. 10 How to Cite?
DOI: http://dx.doi.org/10.3389/fcvm.2023.1066699
Abstract

Myocarditis is a rare complication of Coronavirus Disease 2019 (COVID-19) vaccination. We report a case of an elderly female who presented initially with acute myocarditis, fulminant heart failure, and atrial fibrillation after receiving a modified ribonucleic acid (mRNA) vaccine (BNT162b2). Unlike other patients with vaccine-induced myocarditis, she developed persistent fever, sore throat, polyarthralgia, diffuse macular rash, and lymphadenopathy. After extensive investigation, she was diagnosed with post-vaccination Adult-Onset Still's Disease. The systemic inflammation gradually subsided after the use of non-steroidal anti-inflammatory drugs and systemic steroids. She was discharged from hospital with stable hemodynamics. Methotrexate was subsequently given to maintain long-term remission.


Persistent Identifierhttp://hdl.handle.net/10722/337468
ISSN
2297-055X
2023 Impact Factor: 2.8
2023 SCImago Journal Rankings: 0.863
ISI Accession Number ID
WOS:000957749200001

 

DC FieldValueLanguage
dc.contributor.authorZhou, Mi-
dc.contributor.authorWong, Chun Ka-
dc.contributor.authorYeung, Wan Yin Winnie-
dc.contributor.authorSiu, Chung Wah-
dc.contributor.authorYin, Lixue-
dc.date.accessioned2024-03-11T10:21:05Z-
dc.date.available2024-03-11T10:21:05Z-
dc.date.issued2023-03-15-
dc.identifier.citationFrontiers in Cardiovascular Medicine, 2023, v. 10-
dc.identifier.issn2297-055X-
dc.identifier.urihttp://hdl.handle.net/10722/337468-
dc.description.abstract<p>Myocarditis is a rare complication of Coronavirus Disease 2019 (COVID-19) vaccination. We report a case of an elderly female who presented initially with acute myocarditis, fulminant heart failure, and atrial fibrillation after receiving a modified ribonucleic acid (mRNA) vaccine (BNT162b2). Unlike other patients with vaccine-induced myocarditis, she developed persistent fever, sore throat, polyarthralgia, diffuse macular rash, and lymphadenopathy. After extensive investigation, she was diagnosed with post-vaccination Adult-Onset Still's Disease. The systemic inflammation gradually subsided after the use of non-steroidal anti-inflammatory drugs and systemic steroids. She was discharged from hospital with stable hemodynamics. Methotrexate was subsequently given to maintain long-term remission.</p>-
dc.languageeng-
dc.publisherFrontiers Media-
dc.relation.ispartofFrontiers in Cardiovascular Medicine-
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.-
dc.subjectAdult-Onset Still's Disease (AOSD)-
dc.subjectautoimmune disease-
dc.subjectmRNA vaccine-
dc.subjectmyocarditis-
dc.subjectvaccine-
dc.titleCase report: Coronavirus Disease 2019 (COVID-19) modified RNA vaccination-induced Adult-Onset Still's Disease with fulminant myocarditis as initial presentation-
dc.typeArticle-
dc.identifier.doi10.3389/fcvm.2023.1066699-
dc.identifier.scopuseid_2-s2.0-85151309245-
dc.identifier.volume10-
dc.identifier.eissn2297-055X-
dc.identifier.isiWOS:000957749200001-
dc.identifier.issnl2297-055X-

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