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Conference Paper: WCN23-0350 C-REACTIVE PROTEIN PROMOTES DIABETIC NEPHROPATHY VIA SMAD3 MEDIATED NLRP3 INFLAMMASOME ACTIVATION

TitleWCN23-0350 C-REACTIVE PROTEIN PROMOTES DIABETIC NEPHROPATHY VIA SMAD3 MEDIATED NLRP3 INFLAMMASOME ACTIVATION
Authors
WANG, YChen, HGuo, JShao, BWang, J
Issue Date20-Mar-2023
PublisherElsevier
Abstract

Diabetic nephropathy (DN) is the leading microvascular complications of diabetic mellitus. Our previous research revealed that C-reactive protein (CRP) enhances DN and acute kidney injury, by exacerbating renal fibrosis or inflammation via Smad3 signaling pathways. The study determined whether CRP promotes inflammation via Smad3-mediated NLRP3 inflammasome activation in DN.


Persistent Identifierhttp://hdl.handle.net/10722/338577
ISSN
2468-0249
2023 Impact Factor: 5.7
2023 SCImago Journal Rankings: 1.377

 

DC FieldValueLanguage
dc.contributor.authorWANG, Y-
dc.contributor.authorChen, H-
dc.contributor.authorGuo, J-
dc.contributor.authorShao, B-
dc.contributor.authorWang, J-
dc.date.accessioned2024-03-11T10:29:56Z-
dc.date.available2024-03-11T10:29:56Z-
dc.date.issued2023-03-20-
dc.identifier.issn2468-0249-
dc.identifier.urihttp://hdl.handle.net/10722/338577-
dc.description.abstract<p>Diabetic nephropathy (DN) is the leading microvascular complications of diabetic mellitus. Our previous research revealed that C-reactive protein (CRP) enhances DN and acute kidney injury, by exacerbating renal fibrosis or inflammation via Smad3 signaling pathways. The study determined whether CRP promotes inflammation via Smad3-mediated NLRP3 inflammasome activation in DN.<br></p>-
dc.languageeng-
dc.publisherElsevier-
dc.relation.ispartofKidney International Reports-
dc.titleWCN23-0350 C-REACTIVE PROTEIN PROMOTES DIABETIC NEPHROPATHY VIA SMAD3 MEDIATED NLRP3 INFLAMMASOME ACTIVATION-
dc.typeConference_Paper-
dc.identifier.doi10.1016/j.ekir.2023.02.424-
dc.identifier.volume8-
dc.identifier.issue3-
dc.identifier.eissn2468-0249-
dc.identifier.issnl2468-0249-

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