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- Publisher Website: 10.1016/j.jmbbm.2023.105815
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Article: Antibacterial and physical properties of resin cements containing MgO nanoparticles
| Title | Antibacterial and physical properties of resin cements containing MgO nanoparticles |
|---|---|
| Authors | |
| Keywords | Antibacterial activity Cementation Magnesium oxide Physical properties Resin cement Thermocycling |
| Issue Date | 5-Apr-2023 |
| Publisher | Elsevier |
| Citation | Journal of the Mechanical Behavior of Biomedical Materials, 2023, v. 142 How to Cite? |
| Abstract | Cariogenic bacteria and dental plaque biofilm at prosthesis margins are considered a primary risk factor for failed restorations. Resin cement containing antibacterial agents can be beneficial in controlling bacteria and biofilm. This work aimed to evaluate the impact of incorporating magnesium oxide nanoparticles (MgONPs) as an antibacterial filler into dual-cure resin cement on bacteriostatic activity and physical properties, including mechanical, bonding, and physicochemical properties, as well as performance when subjected to a 5000-times thermocycling regimen. Experimental resin cements containing MgONPs of different mass fractions (0, 2.5%, 5%, 7.5% and 10%) were developed. Results suggested that the inclusion of MgONPs markedly improved the materials’ bacteriostatic effect against Streptococcus mutans without compromising the physical properties when its addition reached 7.5 wt%. The mechanical properties of the specimens did not significantly decline after undergoing aging treatment, except for the flexural properties. In addition, the cements displayed good bonding performance and the material itself was not prone to cohesive fracture in the failure mode analysis. Furthermore, MgONPs possibly have played a role in decelerating material aging during thermocycling and enhancing bonding fastness in the early stage of cementation, which requires further investigation. Overall, developing MgONPs-doped resin cements can be a promising strategy to improve the material's performance in inhibiting cariogenic bacteria at restoration margins, in order to achieve a reduction in biofilm-associated secondary caries and a prolonged restoration lifespan. |
| Persistent Identifier | http://hdl.handle.net/10722/338621 |
| ISSN | 2021 Impact Factor: 4.042 2020 SCImago Journal Rankings: 0.858 |
| ISI Accession Number ID |
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Wang, Yuan | - |
| dc.contributor.author | Wu, Zhongyuan | - |
| dc.contributor.author | Wang, Ting | - |
| dc.contributor.author | Tian, Jing | - |
| dc.contributor.author | Zhou, Zixuan | - |
| dc.contributor.author | Guo, Di | - |
| dc.contributor.author | Tonin, Bruna SH | - |
| dc.contributor.author | Ye, Zhou | - |
| dc.contributor.author | Xu, Haiping | - |
| dc.contributor.author | Fu, Jing | - |
| dc.date.accessioned | 2024-03-11T10:30:15Z | - |
| dc.date.available | 2024-03-11T10:30:15Z | - |
| dc.date.issued | 2023-04-05 | - |
| dc.identifier.citation | Journal of the Mechanical Behavior of Biomedical Materials, 2023, v. 142 | - |
| dc.identifier.issn | 1751-6161 | - |
| dc.identifier.uri | http://hdl.handle.net/10722/338621 | - |
| dc.description.abstract | <p>Cariogenic bacteria and dental plaque <a href="https://www.sciencedirect.com/topics/materials-science/biofilms" title="Learn more about biofilm from ScienceDirect's AI-generated Topic Pages">biofilm</a> at prosthesis margins are considered a primary risk factor for failed restorations. Resin cement containing antibacterial agents can be beneficial in controlling bacteria and <a href="https://www.sciencedirect.com/topics/materials-science/biofilms" title="Learn more about biofilm from ScienceDirect's AI-generated Topic Pages">biofilm</a>. This work aimed to evaluate the impact of incorporating magnesium oxide <a href="https://www.sciencedirect.com/topics/materials-science/nanoparticle" title="Learn more about nanoparticles from ScienceDirect's AI-generated Topic Pages">nanoparticles</a> (MgONPs) as an antibacterial filler into dual-cure resin cement on bacteriostatic activity and physical properties, including mechanical, bonding, and physicochemical properties, as well as performance when subjected to a 5000-times thermocycling regimen. Experimental resin cements containing MgONPs of different mass fractions (0, 2.5%, 5%, 7.5% and 10%) were developed. Results suggested that the inclusion of MgONPs markedly improved the materials’ bacteriostatic effect against <em>Streptococcus mutans</em> without compromising the physical properties when its addition reached 7.5 wt%. The mechanical properties of the specimens did not significantly decline after undergoing aging treatment, except for the flexural properties. In addition, the cements displayed good bonding performance and the material itself was not prone to cohesive fracture in the <a href="https://www.sciencedirect.com/topics/engineering/failure-mode-analysis" title="Learn more about failure mode analysis from ScienceDirect's AI-generated Topic Pages">failure mode analysis</a>. Furthermore, MgONPs possibly have played a role in decelerating <a href="https://www.sciencedirect.com/topics/materials-science/aging-of-materials" title="Learn more about material aging from ScienceDirect's AI-generated Topic Pages">material aging</a> during thermocycling and enhancing bonding fastness in the early stage of cementation, which requires further investigation. Overall, developing MgONPs-doped resin cements can be a promising strategy to improve the material's performance in inhibiting cariogenic bacteria at restoration margins, in order to achieve a reduction in biofilm-associated <a href="https://www.sciencedirect.com/topics/engineering/secondary-caries" title="Learn more about secondary caries from ScienceDirect's AI-generated Topic Pages">secondary caries</a> and a prolonged restoration lifespan.</p> | - |
| dc.language | eng | - |
| dc.publisher | Elsevier | - |
| dc.relation.ispartof | Journal of the Mechanical Behavior of Biomedical Materials | - |
| dc.rights | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. | - |
| dc.subject | Antibacterial activity | - |
| dc.subject | Cementation | - |
| dc.subject | Magnesium oxide | - |
| dc.subject | Physical properties | - |
| dc.subject | Resin cement | - |
| dc.subject | Thermocycling | - |
| dc.title | Antibacterial and physical properties of resin cements containing MgO nanoparticles | - |
| dc.type | Article | - |
| dc.identifier.doi | 10.1016/j.jmbbm.2023.105815 | - |
| dc.identifier.scopus | eid_2-s2.0-85152382262 | - |
| dc.identifier.volume | 142 | - |
| dc.identifier.isi | WOS:000985151400001 | - |
| dc.identifier.issnl | 1878-0180 | - |