File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Book Chapter: DNA-Encoded Chemical Libraries used for Drug Discovery

TitleDNA-Encoded Chemical Libraries used for Drug Discovery
Authors
Zhao, GuixianYang, ShilianLi, XiaoyuLi, Yizhou
KeywordsCombinatorial chemistry
DNA-encoded chemical library
Drug discovery
Drug targets
High-throughput screening
Issue Date16-Dec-2022
Abstract

In the past three decades, DNA-encoded chemical library (DEL) has emerged to become a powerful ultrahigh throughput technology platform for ligand and inhibitor discovery in drug discovery. Today, DEL has been adopted worldwide by the pharmaceutical industry. In this chapter, we review the key technological aspects of DEL, discuss its current state of art, and present salient examples of its applications in modern drug discovery.


Persistent Identifierhttp://hdl.handle.net/10722/339212
ISBN
9781119692744

 

DC FieldValueLanguage
dc.contributor.authorZhao, Guixian-
dc.contributor.authorYang, Shilian-
dc.contributor.authorLi, Xiaoyu-
dc.contributor.authorLi, Yizhou -
dc.date.accessioned2024-03-11T10:34:52Z-
dc.date.available2024-03-11T10:34:52Z-
dc.date.issued2022-12-16-
dc.identifier.isbn9781119692744-
dc.identifier.urihttp://hdl.handle.net/10722/339212-
dc.description.abstract<p>In the past three decades, DNA-encoded chemical library (DEL) has emerged to become a powerful ultrahigh throughput technology platform for ligand and inhibitor discovery in drug discovery. Today, DEL has been adopted worldwide by the pharmaceutical industry. In this chapter, we review the key technological aspects of DEL, discuss its current state of art, and present salient examples of its applications in modern drug discovery.<br></p>-
dc.languageeng-
dc.relation.ispartofNucleic Acids in Medicinal Chemistry and Chemical Biology: Drug Development and Clinical Applications-
dc.subjectCombinatorial chemistry-
dc.subjectDNA-encoded chemical library-
dc.subjectDrug discovery-
dc.subjectDrug targets-
dc.subjectHigh-throughput screening-
dc.titleDNA-Encoded Chemical Libraries used for Drug Discovery-
dc.typeBook_Chapter-
dc.identifier.doi10.1002/9781119692799.ch8-
dc.identifier.scopuseid_2-s2.0-85161107095-
dc.identifier.spage227-
dc.identifier.epage275-
dc.identifier.eisbn9781119692799-

Export via OAI-PMH Interface in XML Formats

OR

Export to Other Non-XML Formats