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Book Chapter: Next-Generation FLT3 Inhibitors for the Treatment of FLT3-Positive AML
Title | Next-Generation FLT3 Inhibitors for the Treatment of FLT3-Positive AML |
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Authors | |
Issue Date | 28-Sep-2023 |
Publisher | Springer Nature Singapore |
Abstract | Tyrosine kinases regulate a wide range of cellular pathways and are crucial to signal transduction. Their aberrant activities can contribute to leukaemogenesis via promoting proliferation, impeding differentiation, and inhibiting apoptosis. In this chapter, we discuss the role of FLT3 inhibition in acute myeloid leukemia (AML) and the use of FLT3 inhibitors in AML. |
Persistent Identifier | http://hdl.handle.net/10722/341835 |
ISBN |
DC Field | Value | Language |
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dc.contributor.author | Singh, Gill Harinder Harry | - |
dc.date.accessioned | 2024-03-26T05:37:34Z | - |
dc.date.available | 2024-03-26T05:37:34Z | - |
dc.date.issued | 2023-09-28 | - |
dc.identifier.isbn | 9789819938094 | - |
dc.identifier.uri | http://hdl.handle.net/10722/341835 | - |
dc.description.abstract | <p>Tyrosine kinases regulate a wide range of cellular pathways and are crucial to signal transduction. Their aberrant activities can contribute to leukaemogenesis via promoting proliferation, impeding differentiation, and inhibiting apoptosis. In this chapter, we discuss the role of FLT3 inhibition in acute myeloid leukemia (AML) and the use of FLT3 inhibitors in AML.<br></p> | - |
dc.language | eng | - |
dc.publisher | Springer Nature Singapore | - |
dc.relation.ispartof | Pathogenesis and Treatment of Leukemia | - |
dc.title | Next-Generation FLT3 Inhibitors for the Treatment of FLT3-Positive AML | - |
dc.type | Book_Chapter | - |
dc.identifier.doi | 10.1007/978-981-99-3810-0_12 | - |
dc.identifier.eisbn | 9789819938100 | - |