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Article: Effect of long-term intake of ginseng extracts on gut microbiota in rats
Title | Effect of long-term intake of ginseng extracts on gut microbiota in rats |
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Authors | |
Keywords | Ginseng extracts Ginsenosides Gut microbiota Probiotics |
Issue Date | 2018 |
Citation | Zhongguo Zhongyao Zazhi, 2018, v. 43, n. 19, p. 3927-3932 How to Cite? |
Abstract | As a traditional Chinese medicine in China, ginseng has a wide range of medicinal and health value. At present, the nutritional value of ginseng as a medicinal food has been a hotspot in studies. Intestinal flora plays an important role in the organism, which has been confirmed by many researchers. In order to find out the effect of long-term intake of ginseng extracts on the gut microbiota structure of rats, MiSeq sequencing platform was applied in macro gene sequencing of cecal contents in the long-term use of ginseng extracts modelin rats. According to the findings, after long-term administration with ginseng extracts, probiotics such as Bifidobacterium, Lactobacillus, Allobaculum and Clostridium, in the intestinal flora of rats were significantly increased, suggesting that long-term intake of ginseng extracts could facilitate the growth of probiotics. Meanwhile, some pathogenic bacteria, such as Butyricimonas, Parabacteroides, Alistipes, Helicobacter, were significantly down-regulated, indicating that long-term intake of ginseng extracts may have a positive effect in inhibiting the colonization of pathogenic bacteria. In conclusion, this study provided an important basis for the research on the effect of long-term use of ginseng extracts on the intestinal flora of rats. |
Persistent Identifier | http://hdl.handle.net/10722/342582 |
ISSN | 2020 SCImago Journal Rankings: 0.172 |
DC Field | Value | Language |
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dc.contributor.author | Sun, Yi Fan | - |
dc.contributor.author | Zhang, Xia | - |
dc.contributor.author | Wang, Xiao Yan | - |
dc.contributor.author | Jia, Wei | - |
dc.date.accessioned | 2024-04-17T07:04:49Z | - |
dc.date.available | 2024-04-17T07:04:49Z | - |
dc.date.issued | 2018 | - |
dc.identifier.citation | Zhongguo Zhongyao Zazhi, 2018, v. 43, n. 19, p. 3927-3932 | - |
dc.identifier.issn | 1001-5302 | - |
dc.identifier.uri | http://hdl.handle.net/10722/342582 | - |
dc.description.abstract | As a traditional Chinese medicine in China, ginseng has a wide range of medicinal and health value. At present, the nutritional value of ginseng as a medicinal food has been a hotspot in studies. Intestinal flora plays an important role in the organism, which has been confirmed by many researchers. In order to find out the effect of long-term intake of ginseng extracts on the gut microbiota structure of rats, MiSeq sequencing platform was applied in macro gene sequencing of cecal contents in the long-term use of ginseng extracts modelin rats. According to the findings, after long-term administration with ginseng extracts, probiotics such as Bifidobacterium, Lactobacillus, Allobaculum and Clostridium, in the intestinal flora of rats were significantly increased, suggesting that long-term intake of ginseng extracts could facilitate the growth of probiotics. Meanwhile, some pathogenic bacteria, such as Butyricimonas, Parabacteroides, Alistipes, Helicobacter, were significantly down-regulated, indicating that long-term intake of ginseng extracts may have a positive effect in inhibiting the colonization of pathogenic bacteria. In conclusion, this study provided an important basis for the research on the effect of long-term use of ginseng extracts on the intestinal flora of rats. | - |
dc.language | eng | - |
dc.relation.ispartof | Zhongguo Zhongyao Zazhi | - |
dc.subject | Ginseng extracts | - |
dc.subject | Ginsenosides | - |
dc.subject | Gut microbiota | - |
dc.subject | Probiotics | - |
dc.title | Effect of long-term intake of ginseng extracts on gut microbiota in rats | - |
dc.type | Article | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.pmid | 30453720 | - |
dc.identifier.scopus | eid_2-s2.0-85056697847 | - |
dc.identifier.volume | 43 | - |
dc.identifier.issue | 19 | - |
dc.identifier.spage | 3927 | - |
dc.identifier.epage | 3932 | - |