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Article: Recommendations for Epstein-Barr virus–based screening for nasopharyngeal cancer in high- and intermediate-risk regions

TitleRecommendations for Epstein-Barr virus–based screening for nasopharyngeal cancer in high- and intermediate-risk regions
Authors
Issue Date1-Feb-2023
PublisherOxford University Press
Citation
Journal of the National Cancer Institute, 2023, v. 115, n. 4, p. 355-364 How to Cite?
Abstract

A meeting of experts was held in November 2021 to review and discuss available data on performance of Epstein-Barr virus (EBV)–based approaches to screen for early stage nasopharyngeal carcinoma (NPC) and methods for the investigation and management of screen-positive individuals. Serum EBV antibody and plasma EBV DNA testing methods were considered. Both approaches were found to have favorable performance characteristics and to be cost-effective in high-risk populations. In addition to endoscopy, use of magnetic resonance imaging (MRI) to investigate screen-positive individuals was found to increase the sensitivity of NPC detection with minimal impact on cost-effectiveness of the screening program.


Persistent Identifierhttp://hdl.handle.net/10722/342852
ISSN
2023 Impact Factor: 9.9
2023 SCImago Journal Rankings: 4.986

 

DC FieldValueLanguage
dc.contributor.authorLam, W K Jacky-
dc.contributor.authorKing, Ann D-
dc.contributor.authorMiller, Jacob A-
dc.contributor.authorLiu, Zhiwei-
dc.contributor.authorYu, Kelly J-
dc.contributor.authorChua, Melvin L K-
dc.contributor.authorMa, Brigette B Y-
dc.contributor.authorChen, Ming Yuan-
dc.contributor.authorPinsky, Benjamin A-
dc.contributor.authorLou, Pei-Jen-
dc.contributor.authorWoo, John K S-
dc.contributor.authorHsu, Wan-Lun-
dc.contributor.authorSimon, Julia-
dc.contributor.authorDoolan, Denise L-
dc.contributor.authorWaterboer, Tim-
dc.contributor.authorHui, Edwin P-
dc.contributor.authorLi, Hui-
dc.contributor.authorTsang, Raymond K-
dc.contributor.authorWong, Kenneth C W-
dc.contributor.authorGoh, Julian P-
dc.contributor.authorVlantis, Alexander C-
dc.contributor.authorAi, Qi Yong-
dc.contributor.authorWong, Lun M-
dc.contributor.authorAbdullah, Victor-
dc.contributor.authorLin, Jin Ching-
dc.contributor.authorChen, Chien-Jen-
dc.contributor.authorPfeiffer, Ruth M-
dc.contributor.authorLe Quynh-Thu,-
dc.contributor.authorLee, Anne W M-
dc.contributor.authorJi, Mingfang-
dc.contributor.authorCao, Sumei-
dc.contributor.authorMa, Jun-
dc.contributor.authorChan, Anthony T C-
dc.contributor.authorChan, K C Allen-
dc.contributor.authorHildesheim, Allan-
dc.date.accessioned2024-05-02T03:06:22Z-
dc.date.available2024-05-02T03:06:22Z-
dc.date.issued2023-02-01-
dc.identifier.citationJournal of the National Cancer Institute, 2023, v. 115, n. 4, p. 355-364-
dc.identifier.issn0027-8874-
dc.identifier.urihttp://hdl.handle.net/10722/342852-
dc.description.abstract<p>A meeting of experts was held in November 2021 to review and discuss available data on performance of Epstein-Barr virus (EBV)–based approaches to screen for early stage nasopharyngeal carcinoma (NPC) and methods for the investigation and management of screen-positive individuals. Serum EBV antibody and plasma EBV DNA testing methods were considered. Both approaches were found to have favorable performance characteristics and to be cost-effective in high-risk populations. In addition to endoscopy, use of magnetic resonance imaging (MRI) to investigate screen-positive individuals was found to increase the sensitivity of NPC detection with minimal impact on cost-effectiveness of the screening program.<br></p>-
dc.languageeng-
dc.publisherOxford University Press-
dc.relation.ispartofJournal of the National Cancer Institute-
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.-
dc.titleRecommendations for Epstein-Barr virus–based screening for nasopharyngeal cancer in high- and intermediate-risk regions-
dc.typeArticle-
dc.identifier.doi10.1093/jnci/djad012-
dc.identifier.scopuseid_2-s2.0-85152169320-
dc.identifier.volume115-
dc.identifier.issue4-
dc.identifier.spage355-
dc.identifier.epage364-
dc.identifier.eissn1460-2105-
dc.identifier.issnl0027-8874-

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