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Article: FMMAS-OCT: Aberration correction for high-resolution cellular imaging

TitleFMMAS-OCT: Aberration correction for high-resolution cellular imaging
Authors
Ge, XinHe, JinChen, SiNi, GuangmingXiong, QiaozhouYang, JielongYu, LequanLiu, LinboBo, En
KeywordsForward model
High resolution
Multiple aperture synthesis
Optical coherence tomography
Issue Date1-Mar-2024
PublisherElsevier
Citation
Optics and Lasers in Engineering, 2024, v. 174 How to Cite?
DOI: http://dx.doi.org/10.1016/j.optlaseng.2023.107964
Abstract

In optical coherence tomography (OCT), spatial resolution and signal strength often suffer due to aberrations from both the imaging system and the sample. In this work, we introduce a novel method, FMMAS (Forward-Model Multiple Aperture Synthesis), which effectively compensates for these aberrations. It combines forward-model (FM) based method for transverse resolution restoration and multiple aperture synthesis (MAS) to mitigate depth domain aberrations. Our proof-of-concept experiment demonstrates a significant improvement in the mean transverse full width at half maximum (FWHM) of microparticles by 46.1 %. Compared to original OCT and FM method, FMMAS produces sharper, 'pencil beam'-like imaging, resolving cell nuclei in swine esophagus ex vivo and human blood cells in vivo, suggesting a potential for significant enhancements in OCT image quality.


Persistent Identifierhttp://hdl.handle.net/10722/347133
ISSN
0143-8166
2023 Impact Factor: 3.5
2023 SCImago Journal Rankings: 1.009

 

DC FieldValueLanguage
dc.contributor.authorGe, Xin-
dc.contributor.authorHe, Jin-
dc.contributor.authorChen, Si-
dc.contributor.authorNi, Guangming-
dc.contributor.authorXiong, Qiaozhou-
dc.contributor.authorYang, Jielong-
dc.contributor.authorYu, Lequan-
dc.contributor.authorLiu, Linbo-
dc.contributor.authorBo, En-
dc.date.accessioned2024-09-18T00:30:33Z-
dc.date.available2024-09-18T00:30:33Z-
dc.date.issued2024-03-01-
dc.identifier.citationOptics and Lasers in Engineering, 2024, v. 174-
dc.identifier.issn0143-8166-
dc.identifier.urihttp://hdl.handle.net/10722/347133-
dc.description.abstract<p>In optical coherence tomography (OCT), spatial resolution and signal strength often suffer due to aberrations from both the imaging system and the sample. In this work, we introduce a novel method, FMMAS (Forward-Model Multiple Aperture Synthesis), which effectively compensates for these aberrations. It combines forward-model (FM) based method for transverse resolution restoration and multiple aperture synthesis (MAS) to mitigate depth domain aberrations. Our proof-of-concept experiment demonstrates a significant improvement in the mean transverse full width at half maximum (FWHM) of microparticles by 46.1 %. Compared to original OCT and FM method, FMMAS produces sharper, 'pencil beam'-like imaging, resolving cell nuclei in swine esophagus ex vivo and human blood cells in vivo, suggesting a potential for significant enhancements in OCT image quality.</p>-
dc.languageeng-
dc.publisherElsevier-
dc.relation.ispartofOptics and Lasers in Engineering-
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.-
dc.subjectForward model-
dc.subjectHigh resolution-
dc.subjectMultiple aperture synthesis-
dc.subjectOptical coherence tomography-
dc.titleFMMAS-OCT: Aberration correction for high-resolution cellular imaging-
dc.typeArticle-
dc.identifier.doi10.1016/j.optlaseng.2023.107964-
dc.identifier.scopuseid_2-s2.0-85179583940-
dc.identifier.volume174-
dc.identifier.eissn1873-0302-
dc.identifier.issnl0143-8166-

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