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- Publisher Website: 10.1016/j.canlet.2023.216152
- Scopus: eid_2-s2.0-85151552927
- PMID: 37023938
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Article: Ferroptosis: Promising approach for cancer and cancer immunotherapy
| Title | Ferroptosis: Promising approach for cancer and cancer immunotherapy |
|---|---|
| Authors | |
| Keywords | Ferroptosis Immunotherapy Tumor microenvironment |
| Issue Date | 1-May-2023 |
| Publisher | Elsevier |
| Citation | Cancer Letters, 2023, v. 561 How to Cite? |
| Abstract | Ferroptosis is the cell death induced by ferrous ions and lipid peroxidation accumulation in tumor cells. Targeting ferroptosis, which is regulated by various metabolic and immune elements, might become a novel strategy for anti-tumor therapy. In this review, we will focus on the mechanism of ferroptosis and its interaction with cancer and tumor immune microenvironment, especially for the relationship between immune cells and ferroptosis. Also, we will discuss the latest preclinical progress of the collaboration between the ferroptosis-targeted drugs and immunotherapy, and the best potential conditions for their combined use. It will present a future insight on the possible value of ferroptosis in cancer immunotherapy. |
| Persistent Identifier | http://hdl.handle.net/10722/348731 |
| ISSN | 2023 Impact Factor: 9.1 2023 SCImago Journal Rankings: 2.595 |
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Zheng, Shuyue | - |
| dc.contributor.author | Guan, Xin Yuan | - |
| dc.date.accessioned | 2024-10-15T00:30:29Z | - |
| dc.date.available | 2024-10-15T00:30:29Z | - |
| dc.date.issued | 2023-05-01 | - |
| dc.identifier.citation | Cancer Letters, 2023, v. 561 | - |
| dc.identifier.issn | 0304-3835 | - |
| dc.identifier.uri | http://hdl.handle.net/10722/348731 | - |
| dc.description.abstract | Ferroptosis is the cell death induced by ferrous ions and lipid peroxidation accumulation in tumor cells. Targeting ferroptosis, which is regulated by various metabolic and immune elements, might become a novel strategy for anti-tumor therapy. In this review, we will focus on the mechanism of ferroptosis and its interaction with cancer and tumor immune microenvironment, especially for the relationship between immune cells and ferroptosis. Also, we will discuss the latest preclinical progress of the collaboration between the ferroptosis-targeted drugs and immunotherapy, and the best potential conditions for their combined use. It will present a future insight on the possible value of ferroptosis in cancer immunotherapy. | - |
| dc.language | eng | - |
| dc.publisher | Elsevier | - |
| dc.relation.ispartof | Cancer Letters | - |
| dc.rights | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. | - |
| dc.subject | Ferroptosis | - |
| dc.subject | Immunotherapy | - |
| dc.subject | Tumor microenvironment | - |
| dc.title | Ferroptosis: Promising approach for cancer and cancer immunotherapy | - |
| dc.type | Article | - |
| dc.identifier.doi | 10.1016/j.canlet.2023.216152 | - |
| dc.identifier.pmid | 37023938 | - |
| dc.identifier.scopus | eid_2-s2.0-85151552927 | - |
| dc.identifier.volume | 561 | - |
| dc.identifier.eissn | 1872-7980 | - |
| dc.identifier.issnl | 0304-3835 | - |