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Article: Degree of chemical functionalization of carbon nanotubes determines tissue distribution and excretion profile

TitleDegree of chemical functionalization of carbon nanotubes determines tissue distribution and excretion profile
Authors
Al-Jamal, Khuloud T.Nunes, AntonioMethven, LauraAli-Boucetta, HaneneLi, ShoupingToma, Francesca M.Herrero, M. AntoniaAl-Jamal, Wafa T.Tena Eikelder, Huub M.M.Foster, JulieMather, StephenPrato, MaurizioBianco, AlbertoKostarelos, Kostas
Keywordsbiodistribution
functionalization
nanotubes
pharmacokinetics
toxicology
Issue Date2012
Citation
Angewandte Chemie - International Edition, 2012, v. 51, n. 26, p. 6389-6393 How to Cite?
DOI: http://dx.doi.org/10.1002/anie.201201991
AbstractGetting rid of the tubes: An assessment of the retention of functionalized multi-walled carbon nanotubes (MWNTs) in the organs of mice was carried out using single photon emission computed tomography and quantitative scintigraphy (see scheme). Increasing the degree of functionalization on MWNTs enhanced renal clearance, while lower functionalization promoted reticuloendethelial system accumulation. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Persistent Identifierhttp://hdl.handle.net/10722/348969
ISSN
1433-7851
2023 Impact Factor: 16.1
2023 SCImago Journal Rankings: 5.300

 

DC FieldValueLanguage
dc.contributor.authorAl-Jamal, Khuloud T.-
dc.contributor.authorNunes, Antonio-
dc.contributor.authorMethven, Laura-
dc.contributor.authorAli-Boucetta, Hanene-
dc.contributor.authorLi, Shouping-
dc.contributor.authorToma, Francesca M.-
dc.contributor.authorHerrero, M. Antonia-
dc.contributor.authorAl-Jamal, Wafa T.-
dc.contributor.authorTena Eikelder, Huub M.M.-
dc.contributor.authorFoster, Julie-
dc.contributor.authorMather, Stephen-
dc.contributor.authorPrato, Maurizio-
dc.contributor.authorBianco, Alberto-
dc.contributor.authorKostarelos, Kostas-
dc.date.accessioned2024-10-17T06:55:17Z-
dc.date.available2024-10-17T06:55:17Z-
dc.date.issued2012-
dc.identifier.citationAngewandte Chemie - International Edition, 2012, v. 51, n. 26, p. 6389-6393-
dc.identifier.issn1433-7851-
dc.identifier.urihttp://hdl.handle.net/10722/348969-
dc.description.abstractGetting rid of the tubes: An assessment of the retention of functionalized multi-walled carbon nanotubes (MWNTs) in the organs of mice was carried out using single photon emission computed tomography and quantitative scintigraphy (see scheme). Increasing the degree of functionalization on MWNTs enhanced renal clearance, while lower functionalization promoted reticuloendethelial system accumulation. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.-
dc.languageeng-
dc.relation.ispartofAngewandte Chemie - International Edition-
dc.subjectbiodistribution-
dc.subjectfunctionalization-
dc.subjectnanotubes-
dc.subjectpharmacokinetics-
dc.subjecttoxicology-
dc.titleDegree of chemical functionalization of carbon nanotubes determines tissue distribution and excretion profile-
dc.typeArticle-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1002/anie.201201991-
dc.identifier.pmid22623333-
dc.identifier.scopuseid_2-s2.0-84862696137-
dc.identifier.volume51-
dc.identifier.issue26-
dc.identifier.spage6389-
dc.identifier.epage6393-
dc.identifier.eissn1521-3773-

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