Links for fulltext
     (May Require Subscription)
Supplementary

Article: Comparative outcomes of single-stage versus two-stage laparoscopic Fowler-Stephens orchidopexy: A systematic review and meta-analysis

TitleComparative outcomes of single-stage versus two-stage laparoscopic Fowler-Stephens orchidopexy: A systematic review and meta-analysis
Authors
Issue Date1-Feb-2025
PublisherGeorg Thieme Verlag / Thieme Publishing
Citation
European Journal of Pediatric Surgery, 2025, v. 35, n. 1, p. 28-35 How to Cite?
Abstract

Introduction: Intra-abdominal testis (IAT) remains a challenging and controversial subset within the management of cryptorchidism. While Fowler-Stephens orchidopexy (FSO) is still being advocated as the gold standard for the treatment of this entity, there is new and conflicting evidence on the comparative outcomes between single- or two-stage laparoscopic FSO (LFSO). The aim of the study is to investigate whether staging has benefits in children receiving LFSO.

Methods: We searched the PubMed, Medline, Embase, and Cochrane Trials databases for studies comparing single- with two-stage LFSO in children from January 1, 1995 to December 31, 2023. We assessed the identified studies for quality and performed a systematic review and meta-analysis in accordance with the Preferred Reporting of Systematic Reviews and Meta-Analyses. The main outcome measures examined were success rate (in terms of the scrotal position of the testis) and testicular atrophy, which were analyzed using fixed effect models.

Results: We included 17 eligible studies that involved a total of 499 operated testes. The overall success rates of single- and two-stage LFSO were 79.4 and 90.3%, respectively. The overall testicular atrophy rates of single- and two-stage LFSO were 17.3 and 11%, respectively. Fixed effect model analysis showed that two-stage LFSO is significantly superior to single-stage LFSO in overall success rate (odds ratio [OR: 2.57]; 95% confidence interval [CI]: 1.50-4.39, p = 0.0006) and testicular atrophy rate (OR: 0.48; 95% CI: 0.28-0.79, p = 0.004). There is no heterogeneity in the reports, and the funnel plot showed no publication bias.

Conclusions: Two-stage LFSO remains the first choice of operation for children with a high IAT, with a significantly higher success rate and a lower testicular atrophy rate.


Persistent Identifierhttp://hdl.handle.net/10722/353901
ISSN
2023 Impact Factor: 1.5
2023 SCImago Journal Rankings: 0.585

 

DC FieldValueLanguage
dc.contributor.authorFung, Adrian Chi Heng-
dc.contributor.authorTsang, Jaime Tze Wing-
dc.contributor.authorLeung, Ling-
dc.contributor.authorChan, Ivy Hau Yee-
dc.contributor.authorWong, Kenneth Kak Yuen-
dc.date.accessioned2025-01-28T00:35:44Z-
dc.date.available2025-01-28T00:35:44Z-
dc.date.issued2025-02-01-
dc.identifier.citationEuropean Journal of Pediatric Surgery, 2025, v. 35, n. 1, p. 28-35-
dc.identifier.issn0939-7248-
dc.identifier.urihttp://hdl.handle.net/10722/353901-
dc.description.abstract<p><strong>Introduction: </strong>Intra-abdominal testis (IAT) remains a challenging and controversial subset within the management of cryptorchidism. While Fowler-Stephens orchidopexy (FSO) is still being advocated as the gold standard for the treatment of this entity, there is new and conflicting evidence on the comparative outcomes between single- or two-stage laparoscopic FSO (LFSO). The aim of the study is to investigate whether staging has benefits in children receiving LFSO.</p><p><strong>Methods: </strong>We searched the PubMed, Medline, Embase, and Cochrane Trials databases for studies comparing single- with two-stage LFSO in children from January 1, 1995 to December 31, 2023. We assessed the identified studies for quality and performed a systematic review and meta-analysis in accordance with the Preferred Reporting of Systematic Reviews and Meta-Analyses. The main outcome measures examined were success rate (in terms of the scrotal position of the testis) and testicular atrophy, which were analyzed using fixed effect models.</p><p><strong>Results: </strong>We included 17 eligible studies that involved a total of 499 operated testes. The overall success rates of single- and two-stage LFSO were 79.4 and 90.3%, respectively. The overall testicular atrophy rates of single- and two-stage LFSO were 17.3 and 11%, respectively. Fixed effect model analysis showed that two-stage LFSO is significantly superior to single-stage LFSO in overall success rate (odds ratio [OR: 2.57]; 95% confidence interval [CI]: 1.50-4.39, <em>p</em> = 0.0006) and testicular atrophy rate (OR: 0.48; 95% CI: 0.28-0.79, <em>p</em> = 0.004). There is no heterogeneity in the reports, and the funnel plot showed no publication bias.</p><p><strong>Conclusions: </strong>Two-stage LFSO remains the first choice of operation for children with a high IAT, with a significantly higher success rate and a lower testicular atrophy rate.</p>-
dc.languageeng-
dc.publisherGeorg Thieme Verlag / Thieme Publishing-
dc.relation.ispartofEuropean Journal of Pediatric Surgery-
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.-
dc.titleComparative outcomes of single-stage versus two-stage laparoscopic Fowler-Stephens orchidopexy: A systematic review and meta-analysis-
dc.typeArticle-
dc.description.naturepreprint-
dc.identifier.doi10.1055/a-2375-9784-
dc.identifier.volume35-
dc.identifier.issue1-
dc.identifier.spage28-
dc.identifier.epage35-
dc.identifier.eissn1439-359X-
dc.identifier.issnl0939-7248-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats