File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: The Role of Non-Coding RNAs in Regulating Cachexia Muscle Atrophy

TitleThe Role of Non-Coding RNAs in Regulating Cachexia Muscle Atrophy
Authors
Chen, GuomingZou, JiayiHe, QianhuaXia, ShuyiXiao, QiliDu, RuoxiZhou, ShengmeiZhang, ChengWang, NingFeng, Yibin
Keywordscachexia
circRNAs
lncRNAs
microRNAs
muscle atrophy
non-coding RNAs
Issue Date2024
Citation
Cells, 2024, v. 13, n. 19, article no. 1620 How to Cite?
DOI: http://dx.doi.org/10.3390/cells13191620
AbstractCachexia is a late consequence of various diseases that is characterized by systemic muscle loss, with or without fat loss, leading to significant mortality. Multiple signaling pathways and molecules that increase catabolism, decrease anabolism, and interfere with muscle regeneration are activated. Non-coding RNAs (ncRNAs), such as microRNAs (miRNAs), long non-coding RNAs (lncRNAs), and circular RNAs (circRNAs), play vital roles in cachexia muscle atrophy. This review mainly provides the mechanisms of specific ncRNAs to regulate muscle loss during cachexia and discusses the role of ncRNAs in cachectic biomarkers and novel therapeutic strategies that could offer new insights for clinical practice.
Persistent Identifierhttp://hdl.handle.net/10722/360341

 

DC FieldValueLanguage
dc.contributor.authorChen, Guoming-
dc.contributor.authorZou, Jiayi-
dc.contributor.authorHe, Qianhua-
dc.contributor.authorXia, Shuyi-
dc.contributor.authorXiao, Qili-
dc.contributor.authorDu, Ruoxi-
dc.contributor.authorZhou, Shengmei-
dc.contributor.authorZhang, Cheng-
dc.contributor.authorWang, Ning-
dc.contributor.authorFeng, Yibin-
dc.date.accessioned2025-09-10T09:06:20Z-
dc.date.available2025-09-10T09:06:20Z-
dc.date.issued2024-
dc.identifier.citationCells, 2024, v. 13, n. 19, article no. 1620-
dc.identifier.urihttp://hdl.handle.net/10722/360341-
dc.description.abstractCachexia is a late consequence of various diseases that is characterized by systemic muscle loss, with or without fat loss, leading to significant mortality. Multiple signaling pathways and molecules that increase catabolism, decrease anabolism, and interfere with muscle regeneration are activated. Non-coding RNAs (ncRNAs), such as microRNAs (miRNAs), long non-coding RNAs (lncRNAs), and circular RNAs (circRNAs), play vital roles in cachexia muscle atrophy. This review mainly provides the mechanisms of specific ncRNAs to regulate muscle loss during cachexia and discusses the role of ncRNAs in cachectic biomarkers and novel therapeutic strategies that could offer new insights for clinical practice.-
dc.languageeng-
dc.relation.ispartofCells-
dc.subjectcachexia-
dc.subjectcircRNAs-
dc.subjectlncRNAs-
dc.subjectmicroRNAs-
dc.subjectmuscle atrophy-
dc.subjectnon-coding RNAs-
dc.titleThe Role of Non-Coding RNAs in Regulating Cachexia Muscle Atrophy-
dc.typeArticle-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.3390/cells13191620-
dc.identifier.pmid39404384-
dc.identifier.scopuseid_2-s2.0-85206277835-
dc.identifier.volume13-
dc.identifier.issue19-
dc.identifier.spagearticle no. 1620-
dc.identifier.epagearticle no. 1620-
dc.identifier.eissn2073-4409-

Export via OAI-PMH Interface in XML Formats

OR

Export to Other Non-XML Formats