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Article: Engineering physical microenvironment for stem cell based regenerative medicine

TitleEngineering physical microenvironment for stem cell based regenerative medicine
Authors
Han, Yu LongWang, ShuqiZhang, XiaohuiLi, YuhuiHuang, GuoyouQi, HaoPingguan-Murphy, BelindaLi, YinghuiLu, Tian JianXu, Feng
Issue Date2014
Citation
Drug Discovery Today, 2014, v. 19, n. 6, p. 763-773 How to Cite?
DOI: http://dx.doi.org/10.1016/j.drudis.2014.01.015
AbstractRegenerative medicine has rapidly evolved over the past decade owing to its potential applications to improve human health. Targeted differentiations of stem cells promise to regenerate a variety of tissues and/or organs despite significant challenges. Recent studies have demonstrated the vital role of the physical microenvironment in regulating stem cell fate and improving differentiation efficiency. In this review, we summarize the main physical cues that are crucial for controlling stem cell differentiation. Recent advances in the technologies for the construction of physical microenvironment and their implications in controlling stem cell fate are also highlighted. © 2014 Elsevier Ltd.
Persistent Identifierhttp://hdl.handle.net/10722/361289
ISSN
1359-6446
2023 Impact Factor: 6.5
2023 SCImago Journal Rankings: 1.586

 

DC FieldValueLanguage
dc.contributor.authorHan, Yu Long-
dc.contributor.authorWang, Shuqi-
dc.contributor.authorZhang, Xiaohui-
dc.contributor.authorLi, Yuhui-
dc.contributor.authorHuang, Guoyou-
dc.contributor.authorQi, Hao-
dc.contributor.authorPingguan-Murphy, Belinda-
dc.contributor.authorLi, Yinghui-
dc.contributor.authorLu, Tian Jian-
dc.contributor.authorXu, Feng-
dc.date.accessioned2025-09-16T04:15:52Z-
dc.date.available2025-09-16T04:15:52Z-
dc.date.issued2014-
dc.identifier.citationDrug Discovery Today, 2014, v. 19, n. 6, p. 763-773-
dc.identifier.issn1359-6446-
dc.identifier.urihttp://hdl.handle.net/10722/361289-
dc.description.abstractRegenerative medicine has rapidly evolved over the past decade owing to its potential applications to improve human health. Targeted differentiations of stem cells promise to regenerate a variety of tissues and/or organs despite significant challenges. Recent studies have demonstrated the vital role of the physical microenvironment in regulating stem cell fate and improving differentiation efficiency. In this review, we summarize the main physical cues that are crucial for controlling stem cell differentiation. Recent advances in the technologies for the construction of physical microenvironment and their implications in controlling stem cell fate are also highlighted. © 2014 Elsevier Ltd.-
dc.languageeng-
dc.relation.ispartofDrug Discovery Today-
dc.titleEngineering physical microenvironment for stem cell based regenerative medicine-
dc.typeArticle-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.drudis.2014.01.015-
dc.identifier.pmid24508818-
dc.identifier.scopuseid_2-s2.0-84902080514-
dc.identifier.volume19-
dc.identifier.issue6-
dc.identifier.spage763-
dc.identifier.epage773-
dc.identifier.eissn1878-5832-

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