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- Publisher Website: 10.3724/zdxbyxb-2023-0619
- Scopus: eid_2-s2.0-85202267327
- PMID: 39183057
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Article: Advances on T cell immunity in bone remodeling and bone regeneration
| Title | Advances on T cell immunity in bone remodeling and bone regeneration |
|---|---|
| Authors | |
| Keywords | Adaptive immunity Bone regeneration Bone remodeling Osteoimmunology Osteoporosis Review T cells Union of fracture |
| Issue Date | 2024 |
| Citation | Zhejiang Da Xue Xue Bao Yi Xue Ban Journal of Zhejiang University Medical Sciences, 2024, v. 53, n. 4, p. 450-459 How to Cite? |
| Abstract | 骨重建和骨再生对于保持骨骼完整性和维持矿物质稳态至关重要。T淋巴细胞为适应性免疫的关键成员，通过产生一系列细胞因子和生长因子，在骨重建和骨再生过程中起着举足轻重的作用。在生理状态下，T淋巴细胞通过与间充质干细胞、成骨细胞、破骨细胞的交互作用参与骨稳态的维持；在病理状态下，T淋巴细胞通过与雌激素、糖皮质激素、甲状旁腺激素的协作参与不同类型骨质疏松的病理过程；在损伤后修复的骨折愈合过程中，T淋巴细胞在炎症血肿期、骨痂形成期和骨重建期发挥了不同的作用。因此，靶向T淋巴细胞成为调节骨稳态的潜在策略。本文综述了T细胞免疫参与骨重建和骨再生的研究进展及相关机制，以期为靶向T淋巴细胞调控骨重建和骨再生提供科学依据。. |
| Persistent Identifier | http://hdl.handle.net/10722/363654 |
| ISSN | 2023 SCImago Journal Rankings: 0.254 |
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Hu, Wenhui | - |
| dc.contributor.author | Deng, Jinxia | - |
| dc.contributor.author | Su, Zhanpeng | - |
| dc.contributor.author | Wang, Haixing | - |
| dc.contributor.author | Lin, Sien | - |
| dc.date.accessioned | 2025-10-10T07:48:24Z | - |
| dc.date.available | 2025-10-10T07:48:24Z | - |
| dc.date.issued | 2024 | - |
| dc.identifier.citation | Zhejiang Da Xue Xue Bao Yi Xue Ban Journal of Zhejiang University Medical Sciences, 2024, v. 53, n. 4, p. 450-459 | - |
| dc.identifier.issn | 1008-9292 | - |
| dc.identifier.uri | http://hdl.handle.net/10722/363654 | - |
| dc.description.abstract | 骨重建和骨再生对于保持骨骼完整性和维持矿物质稳态至关重要。T淋巴细胞为适应性免疫的关键成员，通过产生一系列细胞因子和生长因子，在骨重建和骨再生过程中起着举足轻重的作用。在生理状态下，T淋巴细胞通过与间充质干细胞、成骨细胞、破骨细胞的交互作用参与骨稳态的维持；在病理状态下，T淋巴细胞通过与雌激素、糖皮质激素、甲状旁腺激素的协作参与不同类型骨质疏松的病理过程；在损伤后修复的骨折愈合过程中，T淋巴细胞在炎症血肿期、骨痂形成期和骨重建期发挥了不同的作用。因此，靶向T淋巴细胞成为调节骨稳态的潜在策略。本文综述了T细胞免疫参与骨重建和骨再生的研究进展及相关机制，以期为靶向T淋巴细胞调控骨重建和骨再生提供科学依据。. | - |
| dc.language | eng | - |
| dc.relation.ispartof | Zhejiang Da Xue Xue Bao Yi Xue Ban Journal of Zhejiang University Medical Sciences | - |
| dc.subject | Adaptive immunity | - |
| dc.subject | Bone regeneration | - |
| dc.subject | Bone remodeling | - |
| dc.subject | Osteoimmunology | - |
| dc.subject | Osteoporosis | - |
| dc.subject | Review | - |
| dc.subject | T cells | - |
| dc.subject | Union of fracture | - |
| dc.title | Advances on T cell immunity in bone remodeling and bone regeneration | - |
| dc.type | Article | - |
| dc.description.nature | link_to_subscribed_fulltext | - |
| dc.identifier.doi | 10.3724/zdxbyxb-2023-0619 | - |
| dc.identifier.pmid | 39183057 | - |
| dc.identifier.scopus | eid_2-s2.0-85202267327 | - |
| dc.identifier.volume | 53 | - |
| dc.identifier.issue | 4 | - |
| dc.identifier.spage | 450 | - |
| dc.identifier.epage | 459 | - |