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	Title	Author(s)	Issue Date
	Genomic classification in acute myeloid leukemia Journal:New England Journal of Medicine	Lemonnier, FrançoisInoue, SatoshiMak, Tak W.	2016
	RAIDD Mediates TLR3 and IRF7 Driven Type i Interferon Production Journal:Cellular Physiology and Biochemistry	Maney, Sathish KumarXu, Haifeng C.Huang, JunPandyra, Aleksandra A.Ehlting, ChristianAguilar-Valenzuela, RenanPozdeev, Vitaly I.McIlwain, David R.Zimmermann, AlbertBode, Johannes G.Hengel, HartmutKirschning, Carsten J.Kim, Ira R.Hiscott, JohnBrenner, DirkHäussinger, DieterOhashi, Pamela S.Mak, Tak W.Lang, Karl S.Lang, Philipp A.	2016
	Discovery of 4-(4-aminopyrazolo[1,5-a][1,3,5]triazin-8-yl)benzamides as novel, highly potent and selective, orally bioavailable inhibitors of Tyrosine Threonine Kinase, TTK Journal:Bioorganic and Medicinal Chemistry Letters	Laufer, RadoslawLi, Sze WanLiu, YongNg, GraceLang, YunhuiFeher, MiklosBrokx, RichardBeletskaya, IrinaHodgson, RichardMao, GuodongPlotnikova, OlgaAwrey, Donald E.Mason, Jacqueline M.Wei, XinLin, Dan Chi ChiaChe, YiKiarash, RezaMadeira, BrianFletcher, Graham C.Mak, Tak W.Bray, Mark R.Pauls, Henry W.	2016
	Mutant IDH1 Downregulates ATM and Alters DNA Repair and Sensitivity to DNA Damage Independent of TET2 Journal:Cancer Cell	Inoue, SatoshiLi, Wanda Y.Tseng, AlanBeerman, IsabelElia, Andrew J.Bendall, Sean C.Lemonnier, FrançoisKron, Ken J.Cescon, David W.Hao, ZhenyueLind, Evan F.Takayama, NaoyaPlanello, Aline C.Shen, Shu YiShih, Alan H.Larsen, Dana M.Li, QinxiSnow, Bryan E.Wakeham, AndrewHaight, JillianGorrini, ChiaraBassi, ChristianThu, Kelsie L.Murakami, KiichiElford, Alisha R.Ueda, TakeshiStraley, KimberlyYen, Katharine E.Melino, GerryCimmino, LuisaAifantis, IannisLevine, Ross L.De Carvalho, Daniel D.Lupien, MathieuRossi, Derrick J.Nolan, Garry P.Cairns, Rob A.Mak, Tak W.	2016
	B7-H3 expression in donor T cells and host cells negatively regulates acute graft-versus-host disease lethality Journal:Blood	Veenstra, Rachelle G.Flynn, RyanKreymborg, KatharinaMcDonald-Hyman, CameronSaha, AsimTaylor, Patricia A.Osborn, Mark J.Panoskaltsis-Mortari, AngelaSchmitt-Graeff, AnnetteLieberknecht, ElisabethMurphy, William J.Serody, Jonathan S.Munn, David H.Freeman, Gordon J.Allison, James P.Mak, Tak W.Van Brink, Marcel DenZeiser, RobertBlazar, Bruce R.	2015
	Lipocalin-2 deficiency or blockade protects against aortic abdominal aneurysm development in mice Journal:Cardiovascular Research	Tarín, CarlosFernandez-Garcia, Carlos ErnestoBurillo, ElenaPastor-Vargas, CarlosLlamas-Granda, PatriciaCastejón, BorjaRamos-Mozo, PriscilaTorres-Fonseca, Mónica M.Berger, ThorstenMak, Tak W.Egido, JesúsBlanco-Colio, Luis M.Martín-Ventura, Jose L.	2016
	Erratum: Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia (Nature (2015) 521 (357-361) DOI:10.1038/nature14231) Journal:Nature	Chen, ZhengshanShojaee, SeyedmehdiBuchner, MaikeGeng, HuiminLee, Jae WoongKlemm, LarsTitz, BjornGraeber, Thomas G.Park, EugeneTan, Ying XimSatterthwaite, AnnePaietta, ElisabethHunger, Stephen P.Willman, Cheryl L.Melnick, AriLoh, Mignon L.Jung, Jae U.Coligan, John E.Bolland, SilviaMak, Tak W.Limnander, AndreJumaa, HassanReth, MichaelWeiss, ArthurLowell, Clifford A.Muschen, Markus	2016
	Regulation of the phosphatidylinositide 3-kinase pathway by the lipid phosphatase PTEN Journal:Clinical Chemistry	Bassi, ChristianMak, Tak W.	2016
	Discovery of Pyrazolo[1,5-a]pyrimidine TTK Inhibitors: CFI-402257 is a Potent, Selective, Bioavailable Anticancer Agent Journal:ACS Medicinal Chemistry Letters	Liu, YongLaufer, RadoslawPatel, Narendra KumarNg, GraceSampson, Peter B.Li, Sze WanLang, YunhuiFeher, MiklosBrokx, RichardBeletskaya, IrinaHodgson, RichardPlotnikova, OlgaAwrey, Donald E.Qiu, WeiChirgadze, Nickolay Y.Mason, Jacqueline M.Wei, XinLin, Dan Chi ChiaChe, YiKiarash, RezaFletcher, Graham C.Mak, Tak W.Bray, Mark R.Pauls, Henry W.	2016
	Breaking up is hard to do: PI3K isoforms on the rebound Journal:Cancer Cell	Cescon, David W.Gorrini, ChiaraMak, Tak W.	2015
	Metabolic reprogramming during neuronal differentiation Journal:Cell Death and Differentiation	Agostini, M.Romeo, F.Inoue, S.Niklison-Chirou, M. V.Elia, A. J.Dinsdale, D.Morone, N.Knight, R. A.Mak, T. W.Melino, G.	2016
	The acetyltransferase Tip60 contributes to mammary tumorigenesis by modulating DNA repair Journal:Cell Death and Differentiation	Bassi, C.Li, Y. T.Khu, K.Mateo, F.Baniasadi, P. S.Elia, A.Mason, J.Stambolic, V.Pujana, M. A.Mak, T. W.Gorrini, C.	2016
	Lung Cancer Resets the Liver's Metabolic Clock Journal:Cell Metabolism	Cairns, Rob A.Mak, Tak W.	2016
	Mule Regulates the Intestinal Stem Cell Niche via the Wnt Pathway and Targets EphB3 for Proteasomal and Lysosomal Degradation Journal:Cell Stem Cell	Dominguez-Brauer, CarmenHao, ZhenyueElia, Andrew J.Fortin, Jérôme M.Nechanitzky, RobertBrauer, Patrick M.Sheng, YiMana, Miyeko D.Chio, Iok In ChristineHaight, JillianPollett, AaronCairns, RobertTworzyanski, LeanneInoue, SatoshiReardon, ColinMarques, AnaSilvester, JenniferCox, Maureen A.Wakeham, AndrewYilmaz, Omer H.Sabatini, David M.van Es, Johan H.Clevers, HansSato, ToshiroMak, Tak W.	2016
	The Rho-guanine nucleotide exchange factor PDZ-RhoGEF governs susceptibility to diet-induced obesity and type 2 diabetes Journal:eLife	Chang, Ying JuPownall, ScottJensen, Thomas E.Mouaaz, SamarFoltz, WarrenZhou, LilyLiadis, NicoleWoo, MinnaHao, ZhenyueDutt, PrevinBilan, Philip J.Klip, AmiraMak, TakStambolic, Vuk	2015
	Idh1 mutations contribute to the development of T-cell malignancies in genetically engineered mice Journal:Proceedings of the National Academy of Sciences of the United States of America	Hao, ZhenyueCairns, Rob A.Inoue, SatoshiLi, Wanda Y.Sheng, YiLemonnier, FrançoisWakeham, AndrewSnow, Bryan E.Dominguez-Brauer, CarmenYe, JingLarsen, Dana M.Straley, Kimberly S.Tobin, Erica R.Narayanaswamy, RohiniGaulard, PhilippeMak, Tak W.	2016
	ANP32B deficiency impairs proliferation and suppresses tumor progression by regulating AKT phosphorylation Journal:Cell Death and Disease	Yang, S.Zhou, L.Reilly, P. T.Shen, S. M.He, P.Zhu, X. N.Li, C. X.Wang, L. S.Mak, T. W.Chen, G. Q.Yu, Y.	2016
	Biochemical and Structural Characterization of an Intramolecular Interaction in FOXO3a and Its Binding with p53 Journal:Journal of Molecular Biology	Wang, FengMarshall, Christopher B.Yamamoto, KazuoLi, Guang YaoPlevin, Michael J.You, HanMak, Tak W.Ikura, Mitsuhiko	2008
	CD44 sensitivity of platelet activation, membrane scrambling and adhesion under high arterial shear rates Journal:Thrombosis and Haemostasis	Liu, GuilaiLiu, GuoxingAlzoubi, KousiChatterjee, MadhumitaWalker, BrittaMünzer, PatrickLuo, DongUmbach, Anja T.Elvira, BernatChen, HongVoelkl, JakobFöller, MichaelMak, Tak W.Borst, OliverGawaz, MeinradLang, Florian	2016
	Deletions in the cytoplasmic domain of iRhom1 and iRhom2 promote shedding of the TNF receptor by the protease ADAM17 Journal:Science Signaling	Maney, Sathish K.McIlwain, David R.Polz, RobinPandyra, Aleksandra A.Sundaram, BalamuruganWolff, DoritOhishi, KazuhitoMaretzky, ThorstenBrooke, Matthew A.Evers, AstridVasudevan, Ananda A.JaguvaAghaeepour, NimaScheller, JürgenMünk, CarstenHäussinger, DieterMak, Tak W.Nolan, Garry P.Kelsell, David P.Blobel, Carl P.Lang, Karl S.Lang, Philipp A.	2015