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- Publisher Website: 10.1159/000133685
- Scopus: eid_2-s2.0-0027952909
- PMID: 7904551
- WOS: WOS:A1994MV18600015
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Article: Refined localization of the asparagine synthetase gene (ASNS) to chromosome 7, region q21.3, and characterization of the somatic cell hybrid line 4AF/106/K015
Title | Refined localization of the asparagine synthetase gene (ASNS) to chromosome 7, region q21.3, and characterization of the somatic cell hybrid line 4AF/106/K015 |
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Authors | |
Keywords | Biology Genetics biology Cytology and histology |
Issue Date | 1994 |
Publisher | S Karger AG. The Journal's web site is located at http://www.karger.com/CGR |
Citation | Cytogenetics And Cell Genetics, 1994, v. 66 n. 2, p. 135-138 How to Cite? |
Abstract | We have mapped the asparagine synthetase gene (ASNS) to 7q21.3 by fluorescence in situ hybridization. While this study refined the localization of the gene, it also revealed a rearrangement in a somatic cell hybrid line which was used in previous ASNS mapping. Using additional probes from other regions of human chromosome 7, we showed that this cell line (4AF/106/KO15) contained a rearranged chromosome 7 in which a segment of the long arm was apparently duplicated and inserted into the short arm. Caution should be used therefore when interpreting data obtained from this cell line for gene mapping studies. |
Persistent Identifier | http://hdl.handle.net/10722/42532 |
ISSN | |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Heng, HHQ | en_HK |
dc.contributor.author | Shi, XM | en_HK |
dc.contributor.author | Scherer, SW | en_HK |
dc.contributor.author | Andrulis, IL | en_HK |
dc.contributor.author | Tsui, LC | en_HK |
dc.date.accessioned | 2007-01-29T08:52:20Z | - |
dc.date.available | 2007-01-29T08:52:20Z | - |
dc.date.issued | 1994 | en_HK |
dc.identifier.citation | Cytogenetics And Cell Genetics, 1994, v. 66 n. 2, p. 135-138 | en_HK |
dc.identifier.issn | 0301-0171 | en_HK |
dc.identifier.uri | http://hdl.handle.net/10722/42532 | - |
dc.description.abstract | We have mapped the asparagine synthetase gene (ASNS) to 7q21.3 by fluorescence in situ hybridization. While this study refined the localization of the gene, it also revealed a rearrangement in a somatic cell hybrid line which was used in previous ASNS mapping. Using additional probes from other regions of human chromosome 7, we showed that this cell line (4AF/106/KO15) contained a rearranged chromosome 7 in which a segment of the long arm was apparently duplicated and inserted into the short arm. Caution should be used therefore when interpreting data obtained from this cell line for gene mapping studies. | en_HK |
dc.format.extent | 932489 bytes | - |
dc.format.extent | 25088 bytes | - |
dc.format.mimetype | application/pdf | - |
dc.format.mimetype | application/msword | - |
dc.language | eng | en_HK |
dc.publisher | S Karger AG. The Journal's web site is located at http://www.karger.com/CGR | en_HK |
dc.relation.ispartof | Cytogenetics and Cell Genetics | en_HK |
dc.subject | Biology | en_HK |
dc.subject | Genetics biology | en_HK |
dc.subject | Cytology and histology | en_HK |
dc.title | Refined localization of the asparagine synthetase gene (ASNS) to chromosome 7, region q21.3, and characterization of the somatic cell hybrid line 4AF/106/K015 | en_HK |
dc.type | Article | en_HK |
dc.identifier.openurl | http://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0301-0171&volume=66&spage=135&epage=138&date=1994&atitle=Refined+localization+of+the+asparagine+synthetase+gene+(ASNS)+to+chromosome+7,+region+q21.3,+and+characterization+of+the+somatic+cell+hybrid+line+4AF/106/KO15 | en_HK |
dc.identifier.email | Tsui, LC: tsuilc@hkucc.hku.hk | en_HK |
dc.identifier.authority | Tsui, LC=rp00058 | en_HK |
dc.description.nature | published_or_final_version | en_HK |
dc.identifier.doi | 10.1159/000133685 | - |
dc.identifier.pmid | 7904551 | - |
dc.identifier.scopus | eid_2-s2.0-0027952909 | en_HK |
dc.identifier.volume | 66 | en_HK |
dc.identifier.issue | 2 | en_HK |
dc.identifier.spage | 135 | en_HK |
dc.identifier.epage | 138 | en_HK |
dc.identifier.isi | WOS:A1994MV18600015 | - |
dc.publisher.place | Switzerland | en_HK |
dc.identifier.scopusauthorid | Heng, HHQ=7005338076 | en_HK |
dc.identifier.scopusauthorid | Shi, XM=7402953863 | en_HK |
dc.identifier.scopusauthorid | Scherer, SW=35374654500 | en_HK |
dc.identifier.scopusauthorid | Andrulis, IL=7005655442 | en_HK |
dc.identifier.scopusauthorid | Tsui, LC=7102754167 | en_HK |
dc.identifier.issnl | 0301-0171 | - |