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Article: Increased nausea and dizziness when using tramadol for post-operative patient-controlled analgesia (PCA) compared with morphine after intraoperative loading with morphine

TitleIncreased nausea and dizziness when using tramadol for post-operative patient-controlled analgesia (PCA) compared with morphine after intraoperative loading with morphine
Authors
KeywordsAnalgesia, patient-controlled, morphine
Surgery, lower abdominal
Issue Date1998
PublisherBlackwell Publishing Ltd.
Citation
European Journal of Anaesthesiology, 1998, v. 15 n. 5, p. 565-570 How to Cite?
AbstractThirty-eight ASA I-III patients undergoing lower abdominal operations were randomly allocated to receive either morphine (group M, patient-controlled analgesia bolus = 1 mg of morphine) or tramadol (group T, patient-controlled analgesia bolus = 10 mg of tramadol) for post-operative patient-controlled analgesia (PCA) after receiving morphine intraoperatively. There were no between-group differences in the pain, sedation or vomit scores. The nausea scores were significantly higher in group T in the initial 20 h and between 32 and 36 h (P < 0.01, 0-4 and 8-12 h; P < 0.05, 4-8, 12-16, 16-20 and 32-36 h). The incidence of dizziness was also significantly higher in group T (68.4% vs. 31.6%, group T vs. group M, P < 0.05). There was no difference in the overall satisfaction. We conclude that the use of tramadol, compared with morphine, for post-operative PCA after intraoperative loading with morphine is associated with more nausea and dizziness, but with similar sedation, quality of analgesia and patient satisfaction.
Persistent Identifierhttp://hdl.handle.net/10722/44557
ISSN
2023 Impact Factor: 4.2
2023 SCImago Journal Rankings: 0.987
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorNg, KFJen_HK
dc.contributor.authorTsui, SLen_HK
dc.contributor.authorYang, JCSen_HK
dc.contributor.authorHo, ETFen_HK
dc.date.accessioned2007-10-30T06:04:12Z-
dc.date.available2007-10-30T06:04:12Z-
dc.date.issued1998en_HK
dc.identifier.citationEuropean Journal of Anaesthesiology, 1998, v. 15 n. 5, p. 565-570en_HK
dc.identifier.issn0265-0215en_HK
dc.identifier.urihttp://hdl.handle.net/10722/44557-
dc.description.abstractThirty-eight ASA I-III patients undergoing lower abdominal operations were randomly allocated to receive either morphine (group M, patient-controlled analgesia bolus = 1 mg of morphine) or tramadol (group T, patient-controlled analgesia bolus = 10 mg of tramadol) for post-operative patient-controlled analgesia (PCA) after receiving morphine intraoperatively. There were no between-group differences in the pain, sedation or vomit scores. The nausea scores were significantly higher in group T in the initial 20 h and between 32 and 36 h (P < 0.01, 0-4 and 8-12 h; P < 0.05, 4-8, 12-16, 16-20 and 32-36 h). The incidence of dizziness was also significantly higher in group T (68.4% vs. 31.6%, group T vs. group M, P < 0.05). There was no difference in the overall satisfaction. We conclude that the use of tramadol, compared with morphine, for post-operative PCA after intraoperative loading with morphine is associated with more nausea and dizziness, but with similar sedation, quality of analgesia and patient satisfaction.en_HK
dc.format.extent237540 bytes-
dc.format.extent1881 bytes-
dc.format.extent2837 bytes-
dc.format.mimetypeapplication/pdf-
dc.format.mimetypetext/plain-
dc.languageengen_HK
dc.publisherBlackwell Publishing Ltd.en_HK
dc.relation.ispartofEuropean Journal of Anaesthesiologyen_HK
dc.subjectAnalgesia, patient-controlled, morphineen_HK
dc.subjectSurgery, lower abdominalen_HK
dc.subject.meshAnalgesia,-Patient-Controlleden_HK
dc.subject.meshAnalgesics,-Opioid-adverse-effectsen_HK
dc.subject.meshDizziness-chemically-induceden_HK
dc.subject.meshMorphine-therapeutic-useen_HK
dc.subject.meshPostoperative-Nausea-and-Vomiting-chemically-induceden_HK
dc.titleIncreased nausea and dizziness when using tramadol for post-operative patient-controlled analgesia (PCA) compared with morphine after intraoperative loading with morphineen_HK
dc.typeArticleen_HK
dc.identifier.emailNg, KFJ:jkfng@hkucc.hku.hken_HK
dc.identifier.authorityNg, KFJ=rp00544en_HK
dc.description.naturelink_to_OA_fulltexten_HK
dc.identifier.doi10.1097/00003643-199809000-00010en_HK
dc.identifier.pmid9785072-
dc.identifier.scopuseid_2-s2.0-0031771688en_HK
dc.identifier.hkuros44302-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0031771688&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume15en_HK
dc.identifier.issue5en_HK
dc.identifier.spage565en_HK
dc.identifier.epage570en_HK
dc.identifier.isiWOS:000076123500010-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.issnl0265-0215-

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