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Article: Molecular characterization of isoniazid resistance in Mycobacterium tuberculosis: Identification of a novel mutation in inhA

TitleMolecular characterization of isoniazid resistance in Mycobacterium tuberculosis: Identification of a novel mutation in inhA
Authors
Leung, ETYHo, PLYuen, KYWoo, WLLam, THKao, RYSeto, WHYam, WC
Issue Date2006
PublisherAmerican Society for Microbiology.
Citation
Antimicrobial Agents and Chemotherapy, 2006, v. 50 n. 3, p. 1075-1078 How to Cite?
DOI: http://dx.doi.org/10.1128/AAC.50.3.1075-1078.2006
AbstractMultiplex allele-specific PCRs detecting katG codon 315 and mabA (bp -15) mutations could specifically identify 77.5% of isoniazid-resistant Mycobacterium tuberculosis strains in the South China region. One clinical isolate harboring InhA Ile194Thr was characterized to show strong association with isoniazid resistance in Mycobacterium tuberculosis. Copyright © 2006, American Society for Microbiology. All Rights Reserved.
Persistent Identifierhttp://hdl.handle.net/10722/49176
ISSN
0066-4804
2023 Impact Factor: 4.1
2023 SCImago Journal Rankings: 1.357
PubMed Central ID
PMC1426451
ISI Accession Number ID
WOS:000235786300034
References
References in Scopus

 

DC FieldValueLanguage
dc.contributor.authorLeung, ETYen_HK
dc.contributor.authorHo, PLen_HK
dc.contributor.authorYuen, KYen_HK
dc.contributor.authorWoo, WLen_HK
dc.contributor.authorLam, THen_HK
dc.contributor.authorKao, RYen_HK
dc.contributor.authorSeto, WHen_HK
dc.contributor.authorYam, WCen_HK
dc.date.accessioned2008-06-12T06:36:06Z-
dc.date.available2008-06-12T06:36:06Z-
dc.date.issued2006en_HK
dc.identifier.citationAntimicrobial Agents and Chemotherapy, 2006, v. 50 n. 3, p. 1075-1078en_HK
dc.identifier.issn0066-4804en_HK
dc.identifier.urihttp://hdl.handle.net/10722/49176-
dc.description.abstractMultiplex allele-specific PCRs detecting katG codon 315 and mabA (bp -15) mutations could specifically identify 77.5% of isoniazid-resistant Mycobacterium tuberculosis strains in the South China region. One clinical isolate harboring InhA Ile194Thr was characterized to show strong association with isoniazid resistance in Mycobacterium tuberculosis. Copyright © 2006, American Society for Microbiology. All Rights Reserved.en_HK
dc.format.extent388 bytes-
dc.format.mimetypetext/html-
dc.languageengen_HK
dc.publisherAmerican Society for Microbiology.en_HK
dc.relation.ispartofAntimicrobial Agents and Chemotherapyen_HK
dc.subject.meshAntitubercular Agents - pharmacologyen_HK
dc.subject.meshBacterial Proteins - geneticsen_HK
dc.subject.meshGenes, Bacterialen_HK
dc.subject.meshIsoniazid - pharmacologyen_HK
dc.subject.meshMycobacterium tuberculosis - drug effects - genetics - isolation & purificationen_HK
dc.titleMolecular characterization of isoniazid resistance in Mycobacterium tuberculosis: Identification of a novel mutation in inhAen_HK
dc.typeArticleen_HK
dc.identifier.emailHo, PL:plho@hkucc.hku.hken_HK
dc.identifier.emailYuen, KY:kyyuen@hkucc.hku.hken_HK
dc.identifier.emailLam, TH:hrmrlth@hkucc.hku.hken_HK
dc.identifier.emailKao, RY:rytkao@hkucc.hku.hken_HK
dc.identifier.emailYam, WC:wcyam@hkucc.hku.hken_HK
dc.identifier.authorityHo, PL=rp00406en_HK
dc.identifier.authorityYuen, KY=rp00366en_HK
dc.identifier.authorityLam, TH=rp00326en_HK
dc.identifier.authorityKao, RY=rp00481en_HK
dc.identifier.authorityYam, WC=rp00313en_HK
dc.description.naturelink_to_OA_fulltexten_HK
dc.identifier.doi10.1128/AAC.50.3.1075-1078.2006en_HK
dc.identifier.pmid16495272-
dc.identifier.pmcidPMC1426451en_HK
dc.identifier.scopuseid_2-s2.0-33644680148en_HK
dc.identifier.hkuros118626-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-33644680148&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume50en_HK
dc.identifier.issue3en_HK
dc.identifier.spage1075en_HK
dc.identifier.epage1078en_HK
dc.identifier.isiWOS:000235786300034-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridLeung, ETY=26661142200en_HK
dc.identifier.scopusauthoridHo, PL=7402211363en_HK
dc.identifier.scopusauthoridYuen, KY=36078079100en_HK
dc.identifier.scopusauthoridWoo, WL=12765205700en_HK
dc.identifier.scopusauthoridLam, TH=7202522876en_HK
dc.identifier.scopusauthoridKao, RY=7101675499en_HK
dc.identifier.scopusauthoridSeto, WH=7005799377en_HK
dc.identifier.scopusauthoridYam, WC=7004281720en_HK
dc.identifier.issnl0066-4804-

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