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Article: Estimation of the serial interval of influenza
Title | Estimation of the serial interval of influenza | ||||||||||
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Authors | |||||||||||
Issue Date | 2009 | ||||||||||
Publisher | Lippincott Williams & Wilkins. The Journal's web site is located at http://www.epidem.com | ||||||||||
Citation | Epidemiology, 2009, v. 20 n. 3, p. 344-347 How to Cite? | ||||||||||
Abstract | BACKGROUND: Estimates of the clinical-onset serial interval of human influenza infection (time between onset of symptoms in an index case and a secondary case) are used to inform public health policy and to construct mathematical models of influenza transmission. We estimate the serial interval of laboratory-confirmed influenza transmission in households. METHODS: Index cases were recruited after reporting to a primary healthcare center with symptoms. Members of their households were followed-up with repeated home visits. RESULTS: Assuming a Weibull model and accounting for selection bias inherent in our field study design, we used symptom-onset times from 14 pairs of infector/infectee to estimate a mean serial interval of 3.6 days (95% confidence interval = 2.9-4.3 days), with standard deviation 1.6 days. CONCLUSION: The household serial interval of influenza may be longer than previously estimated. Studies of the complete serial interval, based on transmission in all community contexts, are a priority. © 2009 Lippincott Williams & Wilkins, Inc. | ||||||||||
Persistent Identifier | http://hdl.handle.net/10722/60330 | ||||||||||
ISSN | 2023 Impact Factor: 4.7 2023 SCImago Journal Rankings: 0.655 | ||||||||||
PubMed Central ID | |||||||||||
ISI Accession Number ID |
Funding Information: Supported by the US Centers for Disease Control and Prevention (Grant no: 1 U01 C1000439-01), the Research Fund for the Control of Infectious Disease, Food and Health Bureau, Government of the Hong Kong SAR (Grant no: HKU-AA-23), US National Institutes of Health cooperative agreement 5 U01 GM076497 (Models of Infectious Disease Agent Study, ML), and the Area of Excellence Scheme of the Hong Kong University Grants Committee (Grant no: AoE/M-12/06). | ||||||||||
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DC Field | Value | Language |
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dc.contributor.author | Cowling, BJ | en_HK |
dc.contributor.author | Fang, VJ | en_HK |
dc.contributor.author | Riley, S | en_HK |
dc.contributor.author | Malik Peiris, JS | en_HK |
dc.contributor.author | Leung, GM | en_HK |
dc.date.accessioned | 2010-05-31T04:08:24Z | - |
dc.date.available | 2010-05-31T04:08:24Z | - |
dc.date.issued | 2009 | en_HK |
dc.identifier.citation | Epidemiology, 2009, v. 20 n. 3, p. 344-347 | en_HK |
dc.identifier.issn | 1044-3983 | en_HK |
dc.identifier.uri | http://hdl.handle.net/10722/60330 | - |
dc.description.abstract | BACKGROUND: Estimates of the clinical-onset serial interval of human influenza infection (time between onset of symptoms in an index case and a secondary case) are used to inform public health policy and to construct mathematical models of influenza transmission. We estimate the serial interval of laboratory-confirmed influenza transmission in households. METHODS: Index cases were recruited after reporting to a primary healthcare center with symptoms. Members of their households were followed-up with repeated home visits. RESULTS: Assuming a Weibull model and accounting for selection bias inherent in our field study design, we used symptom-onset times from 14 pairs of infector/infectee to estimate a mean serial interval of 3.6 days (95% confidence interval = 2.9-4.3 days), with standard deviation 1.6 days. CONCLUSION: The household serial interval of influenza may be longer than previously estimated. Studies of the complete serial interval, based on transmission in all community contexts, are a priority. © 2009 Lippincott Williams & Wilkins, Inc. | en_HK |
dc.language | eng | en_HK |
dc.publisher | Lippincott Williams & Wilkins. The Journal's web site is located at http://www.epidem.com | en_HK |
dc.relation.ispartof | Epidemiology | en_HK |
dc.rights | Epidemiology. Copyright © Lippincott Williams & Wilkins. | en_HK |
dc.title | Estimation of the serial interval of influenza | en_HK |
dc.type | Article | en_HK |
dc.identifier.openurl | http://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1044-3983&volume=20&issue=3&spage=344&epage=347&date=2009&atitle=Estimation+of+the+serial+interval+of+influenza | en_HK |
dc.identifier.email | Cowling, BJ: bcowling@hku.hk | en_HK |
dc.identifier.email | Riley, S: steven.riley@hku.hk | en_HK |
dc.identifier.email | Malik Peiris, JS: malik@hkucc.hku.hk | en_HK |
dc.identifier.email | Leung, GM: gmleung@hku.hk | en_HK |
dc.identifier.authority | Cowling, BJ=rp01326 | en_HK |
dc.identifier.authority | Riley, S=rp00511 | en_HK |
dc.identifier.authority | Malik Peiris, JS=rp00410 | en_HK |
dc.identifier.authority | Leung, GM=rp00460 | en_HK |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1097/EDE.0b013e31819d1092 | en_HK |
dc.identifier.pmid | 19279492 | en_HK |
dc.identifier.pmcid | PMC3057478 | - |
dc.identifier.scopus | eid_2-s2.0-67651083503 | en_HK |
dc.identifier.hkuros | 155221 | en_HK |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-67651083503&selection=ref&src=s&origin=recordpage | en_HK |
dc.identifier.volume | 20 | en_HK |
dc.identifier.issue | 3 | en_HK |
dc.identifier.spage | 344 | en_HK |
dc.identifier.epage | 347 | en_HK |
dc.identifier.isi | WOS:000265199800007 | - |
dc.publisher.place | United States | en_HK |
dc.relation.project | Control of Pandemic and Inter-pandemic Influenza | - |
dc.identifier.scopusauthorid | Cowling, BJ=8644765500 | en_HK |
dc.identifier.scopusauthorid | Fang, VJ=24474130400 | en_HK |
dc.identifier.scopusauthorid | Riley, S=7102619416 | en_HK |
dc.identifier.scopusauthorid | Malik Peiris, JS=7005486823 | en_HK |
dc.identifier.scopusauthorid | Leung, GM=7007159841 | en_HK |
dc.identifier.issnl | 1044-3983 | - |