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- Publisher Website: 10.1054/ijom.2002.0377
- Scopus: eid_2-s2.0-0037864213
- PMID: 12767883
- WOS: WOS:000183513900016
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Article: Patient-centred outcome measures for oral mucosal disease are sensitive to treatment
Title | Patient-centred outcome measures for oral mucosal disease are sensitive to treatment |
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Authors | |
Keywords | Corticosteroids Oral lichen planus Outcome measures |
Issue Date | 2003 |
Publisher | Churchill Livingstone. The Journal's web site is located at http://www.elsevier.com/locate/ijom |
Citation | International Journal Of Oral And Maxillofacial Surgery, 2003, v. 32 n. 3, p. 334-336 How to Cite? |
Abstract | The aim of this study was to evaluate the sensitivity of two patient-centred outcome measures to the topical application of a corticosteroid (betamethasone) in the treatment of oral lichen planus (OLP). Forty-eight patients with clinical and histological features of OLP were recruited to take part in a 6-week study of the effectiveness of topical betamethasone for the treatment of symptomatic OLP. Participants completed a questionnaire incorporating the 16-item UK Oral Health Related Quality Of Life measure (OHQOL- UK©) and the 14-item Oral Health Impact Profile (OHIP-14), rated their pain on 'global' and visual analogue scales (VAS) and underwent an oral examination, at the start and end of the trial. Four (8%) patients failed to complete the study. The clinical signs of OLP had improved for half (22) of the patients following treatment. Twenty-nine (66%) reported that their oral pain had reduced ('global' scale). More objectively, there were significant differences in VAS ratings of pain (P=0.005), OHIP-14 scores (P=0.036) and OHQOL-UK© scores (P=0.003) between the start and end of the trial. In conclusion, both OHQOL-UK© and OHIP-14, patient-centred outcome measures are sensitive to the clinical effects of topical betamethasone in the treatment of oral lichen planus. |
Persistent Identifier | http://hdl.handle.net/10722/66585 |
ISSN | 2023 Impact Factor: 2.2 2023 SCImago Journal Rankings: 0.875 |
ISI Accession Number ID | |
References |
DC Field | Value | Language |
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dc.contributor.author | McGrath, C | en_HK |
dc.contributor.author | Hegarty, AM | en_HK |
dc.contributor.author | Hodgson, TA | en_HK |
dc.contributor.author | Porter, SR | en_HK |
dc.date.accessioned | 2010-09-06T05:47:36Z | - |
dc.date.available | 2010-09-06T05:47:36Z | - |
dc.date.issued | 2003 | en_HK |
dc.identifier.citation | International Journal Of Oral And Maxillofacial Surgery, 2003, v. 32 n. 3, p. 334-336 | en_HK |
dc.identifier.issn | 0901-5027 | en_HK |
dc.identifier.uri | http://hdl.handle.net/10722/66585 | - |
dc.description.abstract | The aim of this study was to evaluate the sensitivity of two patient-centred outcome measures to the topical application of a corticosteroid (betamethasone) in the treatment of oral lichen planus (OLP). Forty-eight patients with clinical and histological features of OLP were recruited to take part in a 6-week study of the effectiveness of topical betamethasone for the treatment of symptomatic OLP. Participants completed a questionnaire incorporating the 16-item UK Oral Health Related Quality Of Life measure (OHQOL- UK©) and the 14-item Oral Health Impact Profile (OHIP-14), rated their pain on 'global' and visual analogue scales (VAS) and underwent an oral examination, at the start and end of the trial. Four (8%) patients failed to complete the study. The clinical signs of OLP had improved for half (22) of the patients following treatment. Twenty-nine (66%) reported that their oral pain had reduced ('global' scale). More objectively, there were significant differences in VAS ratings of pain (P=0.005), OHIP-14 scores (P=0.036) and OHQOL-UK© scores (P=0.003) between the start and end of the trial. In conclusion, both OHQOL-UK© and OHIP-14, patient-centred outcome measures are sensitive to the clinical effects of topical betamethasone in the treatment of oral lichen planus. | en_HK |
dc.language | eng | en_HK |
dc.publisher | Churchill Livingstone. The Journal's web site is located at http://www.elsevier.com/locate/ijom | en_HK |
dc.relation.ispartof | International Journal of Oral and Maxillofacial Surgery | en_HK |
dc.subject | Corticosteroids | - |
dc.subject | Oral lichen planus | - |
dc.subject | Outcome measures | - |
dc.subject.mesh | Betamethasone - analogs & derivatives - therapeutic use | en_HK |
dc.subject.mesh | Female | en_HK |
dc.subject.mesh | Glucocorticoids - therapeutic use | en_HK |
dc.subject.mesh | Humans | en_HK |
dc.subject.mesh | Lichen Planus, Oral - drug therapy | en_HK |
dc.subject.mesh | Male | en_HK |
dc.subject.mesh | Middle Aged | en_HK |
dc.subject.mesh | Outcome Assessment (Health Care) - methods | en_HK |
dc.subject.mesh | Pain Measurement | en_HK |
dc.subject.mesh | Quality of Life | en_HK |
dc.subject.mesh | Questionnaires | en_HK |
dc.subject.mesh | Reproducibility of Results | en_HK |
dc.subject.mesh | Sickness Impact Profile | en_HK |
dc.title | Patient-centred outcome measures for oral mucosal disease are sensitive to treatment | en_HK |
dc.type | Article | en_HK |
dc.identifier.openurl | http://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0901-5027&volume=32&spage=334&epage=336&date=2003&atitle=Patient-centred+outcome+measures+for+oral+mucosal+disease+are+sensitive+to+treatment | en_HK |
dc.identifier.email | McGrath, C:mcgrathc@hkucc.hku.hk | en_HK |
dc.identifier.authority | McGrath, C=rp00037 | en_HK |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1054/ijom.2002.0377 | en_HK |
dc.identifier.pmid | 12767883 | - |
dc.identifier.scopus | eid_2-s2.0-0037864213 | en_HK |
dc.identifier.hkuros | 81442 | en_HK |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-0037864213&selection=ref&src=s&origin=recordpage | en_HK |
dc.identifier.volume | 32 | en_HK |
dc.identifier.issue | 3 | en_HK |
dc.identifier.spage | 334 | en_HK |
dc.identifier.epage | 336 | en_HK |
dc.identifier.isi | WOS:000183513900016 | - |
dc.publisher.place | United Kingdom | en_HK |
dc.identifier.scopusauthorid | McGrath, C=7102335507 | en_HK |
dc.identifier.scopusauthorid | Hegarty, AM=7007165343 | en_HK |
dc.identifier.scopusauthorid | Hodgson, TA=7102167887 | en_HK |
dc.identifier.scopusauthorid | Porter, SR=7201730425 | en_HK |
dc.identifier.issnl | 0901-5027 | - |