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- Publisher Website: 10.3760/cma.j.issn.1674-5760.2003.04.005
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Article: Age effect on osteoprotegerin expression in periodontal tissue cells during orthodontic tooth movement
| Title | Age effect on osteoprotegerin expression in periodontal tissue cells during orthodontic tooth movement 增龄因素对鼠正畸牙齿移动中牙周组织骨保护素(OPG)表达的影响 |
|---|---|
| Authors | |
| Keywords | Age Alveolar bone remodelling OPG |
| Issue Date | 2003 |
| Publisher | Peking University, Health Science Center. The Journal's web site is located at http://new.med.wanfangdata.com.cn/Periodical/kqzjx |
| Citation | Chinese Journal of Orthodontics, 2003, v. 10 n. 4, p. 164-167 How to Cite? 口腔正畸學, 2003, v. 10 n. 4, p. 164-167 How to Cite? |
| Abstract | 的比较在正畸牙齿移动中幼年鼠和成年鼠牙周组织骨保护素(osteoprotegerin,OPG)信使RNA(mRNA)表达的不同,以探讨增龄因素影响正畸骨改建的分子机制.方法以4周(幼年鼠)和24周(成年鼠)雄性大鼠为实验动物,牵引左上第一磨牙近中移动为正畸牙齿移动模型,原位杂交检测牙周膜组织OPG mRNA的表达.结果1.幼年鼠正畸牙齿移动中加力后3小时张力侧近牙槽骨表面可见OPG表达阳性细胞排列;与幼年鼠相比,成年鼠加力后牵张侧牙周膜细胞的OPG mRNA表达没有明显改变.2.幼年鼠加力后6小时开始压力侧即可观察到破骨细胞的数目明显增多,成年鼠加力后,压力侧加力24小时可见破骨细胞;无论幼年和成年鼠压力侧牙周膜细胞的OPG mRNA表达在加力前后均未见明显改变.结论增龄因素使牙周组织内OPG表达明显增强;成年牙周组织中较强的OPG表达可能与成人正畸出现的牙槽骨吸收、牙齿移动迟缓相关. |
| Persistent Identifier | http://hdl.handle.net/10722/66851 |
| ISSN |
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Li, XT | en_HK |
| dc.contributor.author | Yang, Y | en_HK |
| dc.contributor.author | Zhang, D | en_HK |
| dc.contributor.author | Fu, MK | en_HK |
| dc.date.accessioned | 2010-09-06T05:49:53Z | - |
| dc.date.available | 2010-09-06T05:49:53Z | - |
| dc.date.issued | 2003 | en_HK |
| dc.identifier.citation | Chinese Journal of Orthodontics, 2003, v. 10 n. 4, p. 164-167 | en_HK |
| dc.identifier.citation | 口腔正畸學, 2003, v. 10 n. 4, p. 164-167 | - |
| dc.identifier.issn | 1005-0191 | en_HK |
| dc.identifier.uri | http://hdl.handle.net/10722/66851 | - |
| dc.description.abstract | 的比较在正畸牙齿移动中幼年鼠和成年鼠牙周组织骨保护素(osteoprotegerin,OPG)信使RNA(mRNA)表达的不同,以探讨增龄因素影响正畸骨改建的分子机制.方法以4周(幼年鼠)和24周(成年鼠)雄性大鼠为实验动物,牵引左上第一磨牙近中移动为正畸牙齿移动模型,原位杂交检测牙周膜组织OPG mRNA的表达.结果1.幼年鼠正畸牙齿移动中加力后3小时张力侧近牙槽骨表面可见OPG表达阳性细胞排列;与幼年鼠相比,成年鼠加力后牵张侧牙周膜细胞的OPG mRNA表达没有明显改变.2.幼年鼠加力后6小时开始压力侧即可观察到破骨细胞的数目明显增多,成年鼠加力后,压力侧加力24小时可见破骨细胞;无论幼年和成年鼠压力侧牙周膜细胞的OPG mRNA表达在加力前后均未见明显改变.结论增龄因素使牙周组织内OPG表达明显增强;成年牙周组织中较强的OPG表达可能与成人正畸出现的牙槽骨吸收、牙齿移动迟缓相关. | - |
| dc.language | chi | en_HK |
| dc.publisher | Peking University, Health Science Center. The Journal's web site is located at http://new.med.wanfangdata.com.cn/Periodical/kqzjx | en_HK |
| dc.relation.ispartof | Chinese Journal of Orthodontics | en_HK |
| dc.subject | Age | - |
| dc.subject | Alveolar bone remodelling | - |
| dc.subject | OPG | - |
| dc.title | Age effect on osteoprotegerin expression in periodontal tissue cells during orthodontic tooth movement | en_HK |
| dc.title | 增龄因素对鼠正畸牙齿移动中牙周组织骨保护素(OPG)表达的影响 | - |
| dc.type | Article | en_HK |
| dc.identifier.email | Yang, Y: yangyanq@hkucc.hku.hk | en_HK |
| dc.identifier.authority | Yang, Y=rp00045 | en_HK |
| dc.identifier.doi | 10.3760/cma.j.issn.1674-5760.2003.04.005 | - |
| dc.identifier.hkuros | 146517 | en_HK |
| dc.identifier.issnl | 1005-0191 | - |