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Article: Increasing Scans Per Examination Improves the Reproducibility on Retinal Nerve Fiber Layer Measurements by Optical Coherence Tomography

TitleIncreasing Scans Per Examination Improves the Reproducibility on Retinal Nerve Fiber Layer Measurements by Optical Coherence Tomography
Authors
KeywordsGlaucoma
Optic nerve imaging
Optical coherence tomography
Reproducibility
Retinal nerve fiber layer
Retinal nerve fiber layer thickness
Issue Date2004
PublisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.optvissci.com
Citation
Optometry And Vision Science, 2004, v. 81 n. 4, p. 268-271 How to Cite?
AbstractPurpose. To investigate whether increasing the number of scans per examination would improve the reproducibility of retinal nerve fiber layer (RNFL) measurements by optical coherence tomography (OCT) in healthy and glaucomatous eyes. Methods. A total of 28 eyes of 28 healthy subjects and 20 eyes of 20 patients with primary chronic open-angle glaucoma were recruited. OCT RNFL assessments were obtained in one randomly selected eye. Each subject underwent seven scans on five separate occasions within a 1-month period. Results. In the healthy group, the intervisit mean coefficient of variations (COV's) for the average RNFL thickness (100 sampling points) and the quadrant RNFL measurements (25 sampling points) were similar in a series of three, five, and seven scans per examination (p > 0.05), but COV's for the two clock-hour segment measurements (seven sampling points, superotemporal and inferotemporal) were significantly lower in a series of five and seven scans per examination than that of three scans per examinations (p < 0.01). In the glaucoma groups, COV's for the two quadrant (superior and inferior) and five clock-hour segment RNFL measurements (superior, superotemporal, temporal, inferotemporal, and superonasal) were significantly lower in a series of five and seven scans per examination than that of three scans per examination (p < 0.01). There was no statistical difference in the COV's between a series of five scans and that of seven scans per examination in all OCT RNFL thickness parameters in healthy and glaucomatous eyes (p > 0.05). Similar results were observed with intravisit COV comparisons. Conclusion. Increasing the number of scans per examination may improve the reproducibility of quadrant and clock-hour segment OCT RNFL measurements in healthy and glaucomatous eyes. A series of five scans per examination is recommended for OCT RNFL measurements.
Persistent Identifierhttp://hdl.handle.net/10722/67632
ISSN
2023 Impact Factor: 1.6
2023 SCImago Journal Rankings: 0.585
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorMok, KHen_HK
dc.contributor.authorLee, VWHen_HK
dc.contributor.authorSo, KFen_HK
dc.date.accessioned2010-09-06T05:56:51Z-
dc.date.available2010-09-06T05:56:51Z-
dc.date.issued2004en_HK
dc.identifier.citationOptometry And Vision Science, 2004, v. 81 n. 4, p. 268-271en_HK
dc.identifier.issn1040-5488en_HK
dc.identifier.urihttp://hdl.handle.net/10722/67632-
dc.description.abstractPurpose. To investigate whether increasing the number of scans per examination would improve the reproducibility of retinal nerve fiber layer (RNFL) measurements by optical coherence tomography (OCT) in healthy and glaucomatous eyes. Methods. A total of 28 eyes of 28 healthy subjects and 20 eyes of 20 patients with primary chronic open-angle glaucoma were recruited. OCT RNFL assessments were obtained in one randomly selected eye. Each subject underwent seven scans on five separate occasions within a 1-month period. Results. In the healthy group, the intervisit mean coefficient of variations (COV's) for the average RNFL thickness (100 sampling points) and the quadrant RNFL measurements (25 sampling points) were similar in a series of three, five, and seven scans per examination (p > 0.05), but COV's for the two clock-hour segment measurements (seven sampling points, superotemporal and inferotemporal) were significantly lower in a series of five and seven scans per examination than that of three scans per examinations (p < 0.01). In the glaucoma groups, COV's for the two quadrant (superior and inferior) and five clock-hour segment RNFL measurements (superior, superotemporal, temporal, inferotemporal, and superonasal) were significantly lower in a series of five and seven scans per examination than that of three scans per examination (p < 0.01). There was no statistical difference in the COV's between a series of five scans and that of seven scans per examination in all OCT RNFL thickness parameters in healthy and glaucomatous eyes (p > 0.05). Similar results were observed with intravisit COV comparisons. Conclusion. Increasing the number of scans per examination may improve the reproducibility of quadrant and clock-hour segment OCT RNFL measurements in healthy and glaucomatous eyes. A series of five scans per examination is recommended for OCT RNFL measurements.en_HK
dc.languageengen_HK
dc.publisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.optvissci.comen_HK
dc.relation.ispartofOptometry and Vision Scienceen_HK
dc.rightsOptometry and Vision Science. Copyright © Lippincott Williams & Wilkins.en_HK
dc.subjectGlaucoma-
dc.subjectOptic nerve imaging-
dc.subjectOptical coherence tomography-
dc.subjectReproducibility-
dc.subjectRetinal nerve fiber layer-
dc.subjectRetinal nerve fiber layer thickness-
dc.subject.meshAdulten_HK
dc.subject.meshFemaleen_HK
dc.subject.meshGlaucoma - diagnosisen_HK
dc.subject.meshHumansen_HK
dc.subject.meshMaleen_HK
dc.subject.meshMiddle Ageden_HK
dc.subject.meshNerve Fibers - ultrastructureen_HK
dc.subject.meshReproducibility of Resultsen_HK
dc.subject.meshRetina - ultrastructureen_HK
dc.subject.meshTomography, Optical Coherenceen_HK
dc.titleIncreasing Scans Per Examination Improves the Reproducibility on Retinal Nerve Fiber Layer Measurements by Optical Coherence Tomographyen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1040-5488&volume=81 no 4&spage=267&epage=270&date=2004&atitle=Increasing+scans+per+examination+improves+the+reproducibility+on+retinal+nerve+fiber+layer+measurements+by+optical+coherence+tomographyen_HK
dc.identifier.emailSo, KF:hrmaskf@hkucc.hku.hken_HK
dc.identifier.authoritySo, KF=rp00329en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1097/00006324-200404000-00013en_HK
dc.identifier.pmid15097769-
dc.identifier.scopuseid_2-s2.0-1942542361en_HK
dc.identifier.hkuros95516en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-1942542361&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume81en_HK
dc.identifier.issue4en_HK
dc.identifier.spage268en_HK
dc.identifier.epage271en_HK
dc.identifier.isiWOS:000221079600008-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridMok, KH=7103141187en_HK
dc.identifier.scopusauthoridLee, VWH=7402507569en_HK
dc.identifier.scopusauthoridSo, KF=34668391300en_HK
dc.identifier.issnl1040-5488-

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