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Article: Nuclear matrix of human nasopharyngeal carcinoma cells in culture: a preliminary report

TitleNuclear matrix of human nasopharyngeal carcinoma cells in culture: a preliminary report
Authors
Keywordsnasopharyngeal carcinoma
NPC/CUHK1 cell line
nuclear matrix
Issue Date1996
PublisherDemetrios A Spandidos Ed & Pub. The Journal's web site is located at http://147.52.72.117/OR/or.htm
Citation
Oncology Reports, 1996, v. 3, p. 691-693 How to Cite?
AbstractNuclear matrix is a scaffold-like structure of the nucleus after sequential treatments with detergents, DNase, and high salt buffers. Its involvement in various cellular activities has been emphasised in various studies. In this study, nuclear matrix of two human nasopharyngeal carcinoma cell lines were compared and analysed in terms of their morphological appearance and electrophoretic patterns of proteins. The stability of nuclear matrices against enzymatic digestion was found to be similar in these two cell lines. However, cell line specific nuclear matrix proteins were detected in each cell line. The significance of these proteins in cellular function and oncogenesis will be investigated in due course.
Persistent Identifierhttp://hdl.handle.net/10722/67906
ISSN
2023 Impact Factor: 3.8
2023 SCImago Journal Rankings: 0.864
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorFan, CSen_HK
dc.contributor.authorYam, HFen_HK
dc.contributor.authorYang, Len_HK
dc.contributor.authorChew-Cheng, SBen_HK
dc.contributor.authorWang, SWen_HK
dc.contributor.authorChan, HBen_HK
dc.contributor.authorTsao, GSWen_HK
dc.contributor.authorLee, JCKen_HK
dc.contributor.authorChew, ECen_HK
dc.date.accessioned2010-09-06T05:59:21Z-
dc.date.available2010-09-06T05:59:21Z-
dc.date.issued1996en_HK
dc.identifier.citationOncology Reports, 1996, v. 3, p. 691-693en_HK
dc.identifier.issn1021-335Xen_HK
dc.identifier.urihttp://hdl.handle.net/10722/67906-
dc.description.abstractNuclear matrix is a scaffold-like structure of the nucleus after sequential treatments with detergents, DNase, and high salt buffers. Its involvement in various cellular activities has been emphasised in various studies. In this study, nuclear matrix of two human nasopharyngeal carcinoma cell lines were compared and analysed in terms of their morphological appearance and electrophoretic patterns of proteins. The stability of nuclear matrices against enzymatic digestion was found to be similar in these two cell lines. However, cell line specific nuclear matrix proteins were detected in each cell line. The significance of these proteins in cellular function and oncogenesis will be investigated in due course.-
dc.languageengen_HK
dc.publisherDemetrios A Spandidos Ed & Pub. The Journal's web site is located at http://147.52.72.117/OR/or.htmen_HK
dc.relation.ispartofOncology Reportsen_HK
dc.subjectnasopharyngeal carcinoma-
dc.subjectNPC/CUHK1 cell line-
dc.subjectnuclear matrix-
dc.subject.meshCarcinogenesis-
dc.subject.meshCell nucleus matrix-
dc.subject.meshCell structure-
dc.subject.meshElectrophoretic mobility-
dc.subject.meshEpstein barr virus-
dc.titleNuclear matrix of human nasopharyngeal carcinoma cells in culture: a preliminary reporten_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1021-335X&volume=3&spage=691&epage=693&date=1996&atitle=Nuclear+matrix+of+human+nasopharyngeal+carcinoma+cells+in+culture:+a+preliminary+reporten_HK
dc.identifier.emailTsao, GSW: gswtsao@hkucc.hku.hken_HK
dc.identifier.authorityTsao, GSW=rp00399en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.pmid21594437-
dc.identifier.scopuseid_2-s2.0-0029942286-
dc.identifier.hkuros14748en_HK
dc.identifier.isiWOS:A1996UT75900018-
dc.identifier.issnl1021-335X-

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