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Article: Children with respiratory disease associated with metapneumovirus in Hong Kong
Title | Children with respiratory disease associated with metapneumovirus in Hong Kong |
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Authors | |
Issue Date | 2003 |
Publisher | US Department of Health and Human Services, Centers for Disease Control and Prevention. The Journal's web site is located at http://www.cdc.gov/ncidod/EID/index.htm |
Citation | Emerging Infectious Diseases, 2003, v. 9 n. 6, p. 628-633 How to Cite? |
Abstract | Human metapneumovirus (HMPV) is a newly discovered pathogen thought to be associated with respiratory disease. We report the results of a study of 587 children hospitalized with respiratory infection over a 13-month period. HMPV was detected in the nasopharyngeal aspirates from 32 (5.5%) children by reverse transcription-polymerase chain reaction. HMPV infection was associated with clinical diagnoses of pneumonia (36%), asthma exacerbation (23%), or acute bronchiolitis (10%). When compared to those with respiratory syncytial virus infection, children with HMPV infection were older, and wheezing was more likely to represent asthma exacerbation rather than acute bronchiolitis. HMPV viral activity peaked during the spring-summer period in Hong Kong. Phylogenetically, all HMPV virus strains from Hong Kong belonged to one of the two genetic lineages previously described. HMPV contributed to 441.6 hospital admissions per 100,000 population <6 years of age. |
Persistent Identifier | http://hdl.handle.net/10722/72365 |
ISSN | 2023 Impact Factor: 7.2 2023 SCImago Journal Rankings: 2.117 |
PubMed Central ID | |
ISI Accession Number ID | |
References |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Peiris, JSM | en_HK |
dc.contributor.author | Tang, WH | en_HK |
dc.contributor.author | Chan, KH | en_HK |
dc.contributor.author | Khong, PL | en_HK |
dc.contributor.author | Guan, Y | en_HK |
dc.contributor.author | Lau, YL | en_HK |
dc.contributor.author | Chiu, SS | en_HK |
dc.date.accessioned | 2010-09-06T06:40:59Z | - |
dc.date.available | 2010-09-06T06:40:59Z | - |
dc.date.issued | 2003 | en_HK |
dc.identifier.citation | Emerging Infectious Diseases, 2003, v. 9 n. 6, p. 628-633 | en_HK |
dc.identifier.issn | 1080-6040 | en_HK |
dc.identifier.uri | http://hdl.handle.net/10722/72365 | - |
dc.description.abstract | Human metapneumovirus (HMPV) is a newly discovered pathogen thought to be associated with respiratory disease. We report the results of a study of 587 children hospitalized with respiratory infection over a 13-month period. HMPV was detected in the nasopharyngeal aspirates from 32 (5.5%) children by reverse transcription-polymerase chain reaction. HMPV infection was associated with clinical diagnoses of pneumonia (36%), asthma exacerbation (23%), or acute bronchiolitis (10%). When compared to those with respiratory syncytial virus infection, children with HMPV infection were older, and wheezing was more likely to represent asthma exacerbation rather than acute bronchiolitis. HMPV viral activity peaked during the spring-summer period in Hong Kong. Phylogenetically, all HMPV virus strains from Hong Kong belonged to one of the two genetic lineages previously described. HMPV contributed to 441.6 hospital admissions per 100,000 population <6 years of age. | en_HK |
dc.language | eng | en_HK |
dc.publisher | US Department of Health and Human Services, Centers for Disease Control and Prevention. The Journal's web site is located at http://www.cdc.gov/ncidod/EID/index.htm | en_HK |
dc.relation.ispartof | Emerging Infectious Diseases | en_HK |
dc.subject.mesh | Child | en_HK |
dc.subject.mesh | Female | en_HK |
dc.subject.mesh | Fever - diagnosis | en_HK |
dc.subject.mesh | Hong Kong - epidemiology | en_HK |
dc.subject.mesh | Hospitalization | en_HK |
dc.subject.mesh | Humans | en_HK |
dc.subject.mesh | Infant | en_HK |
dc.subject.mesh | Influenza A virus - isolation & purification | en_HK |
dc.subject.mesh | Influenza, Human - complications - diagnosis - epidemiology | en_HK |
dc.subject.mesh | Male | en_HK |
dc.subject.mesh | Metapneumovirus - isolation & purification | en_HK |
dc.subject.mesh | Paramyxoviridae Infections - diagnosis - epidemiology - virology | en_HK |
dc.subject.mesh | Phylogeny | en_HK |
dc.subject.mesh | Respiratory Syncytial Virus Infections - diagnosis - epidemiology - virology | en_HK |
dc.subject.mesh | Respiratory Syncytial Viruses - isolation & purification | en_HK |
dc.subject.mesh | Respiratory Tract Infections - diagnosis - epidemiology - virology | en_HK |
dc.title | Children with respiratory disease associated with metapneumovirus in Hong Kong | en_HK |
dc.type | Article | en_HK |
dc.identifier.openurl | http://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1080-6040&volume=9&issue=6&spage=628&epage=633&date=2003&atitle=Children+with+Respiratory+Disease+Associated+with+Metapneumovirus+in+Hong+Kong | en_HK |
dc.identifier.email | Peiris, JSM: malik@hkucc.hku.hk | en_HK |
dc.identifier.email | Khong, PL: plkhong@hkucc.hku.hk | en_HK |
dc.identifier.email | Guan, Y: yguan@hkucc.hku.hk | en_HK |
dc.identifier.email | Lau, YL: lauylung@hku.hk | en_HK |
dc.identifier.email | Chiu, SS: ssschiu@hku.hk | en_HK |
dc.identifier.authority | Peiris, JSM=rp00410 | en_HK |
dc.identifier.authority | Khong, PL=rp00467 | en_HK |
dc.identifier.authority | Guan, Y=rp00397 | en_HK |
dc.identifier.authority | Lau, YL=rp00361 | en_HK |
dc.identifier.authority | Chiu, SS=rp00421 | en_HK |
dc.description.nature | link_to_OA_fulltext | - |
dc.identifier.pmid | 12781000 | - |
dc.identifier.pmcid | PMC3000155 | - |
dc.identifier.scopus | eid_2-s2.0-0037711390 | en_HK |
dc.identifier.hkuros | 76929 | en_HK |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-0037711390&selection=ref&src=s&origin=recordpage | en_HK |
dc.identifier.volume | 9 | en_HK |
dc.identifier.issue | 6 | en_HK |
dc.identifier.spage | 628 | en_HK |
dc.identifier.epage | 633 | en_HK |
dc.identifier.isi | WOS:000183291900003 | - |
dc.publisher.place | United States | en_HK |
dc.identifier.scopusauthorid | Peiris, JSM=7005486823 | en_HK |
dc.identifier.scopusauthorid | Tang, WH=7403430888 | en_HK |
dc.identifier.scopusauthorid | Chan, KH=7406034307 | en_HK |
dc.identifier.scopusauthorid | Khong, PL=7006693233 | en_HK |
dc.identifier.scopusauthorid | Guan, Y=7202924055 | en_HK |
dc.identifier.scopusauthorid | Lau, YL=7201403380 | en_HK |
dc.identifier.scopusauthorid | Chiu, SS=7202291500 | en_HK |
dc.identifier.issnl | 1080-6040 | - |