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Article: Successful mismatched sibling cord blood transplant in Hb Bart's disease

TitleSuccessful mismatched sibling cord blood transplant in Hb Bart's disease
Authors
Zhou, XHa, SYChan, GCFLuk, CWChan, VHawkins, BLam, YHLiang, RHSLau, YL
KeywordsCord blood transplantation
Hb Bart's disease
Hemoglobin F
HLA mismatched
Immune thrombocytopenia
Issue Date2001
PublisherNature Publishing Group. The Journal's web site is located at http://www.nature.com/bmt
Citation
Bone Marrow Transplantation, 2001, v. 28 n. 1, p. 105-107 How to Cite?
DOI: http://dx.doi.org/10.1038/sj.bmt.1703104
AbstractA 20-month-old girl with Hb Bart's disease, who had survived neonatal complications, underwent HLA-DR antigen mismatched sibling cord blood transplantation successfully. Immune thrombocytopenia, which occurred around 2.5 months after transplant, responded to intravenous γ-globulin. The fetal hemoglobin level rose to a peak of 52.3% on day +69 post transplant and declined gradually during the following year. Ten percent of hemoglobin Bart's was detected 2 months after transplant and this reflects the α-thalassemia trait of the donor.
Persistent Identifierhttp://hdl.handle.net/10722/77037
ISSN
0268-3369
2021 Impact Factor: 5.174
2020 SCImago Journal Rankings: 1.609
ISI Accession Number ID
WOS:000170111800017
References
References in Scopus

 

DC FieldValueLanguage
dc.contributor.authorZhou, Xen_HK
dc.contributor.authorHa, SYen_HK
dc.contributor.authorChan, GCFen_HK
dc.contributor.authorLuk, CWen_HK
dc.contributor.authorChan, Ven_HK
dc.contributor.authorHawkins, Ben_HK
dc.contributor.authorLam, YHen_HK
dc.contributor.authorLiang, RHSen_HK
dc.contributor.authorLau, YLen_HK
dc.date.accessioned2010-09-06T07:27:35Z-
dc.date.available2010-09-06T07:27:35Z-
dc.date.issued2001en_HK
dc.identifier.citationBone Marrow Transplantation, 2001, v. 28 n. 1, p. 105-107en_HK
dc.identifier.issn0268-3369en_HK
dc.identifier.urihttp://hdl.handle.net/10722/77037-
dc.description.abstractA 20-month-old girl with Hb Bart's disease, who had survived neonatal complications, underwent HLA-DR antigen mismatched sibling cord blood transplantation successfully. Immune thrombocytopenia, which occurred around 2.5 months after transplant, responded to intravenous γ-globulin. The fetal hemoglobin level rose to a peak of 52.3% on day +69 post transplant and declined gradually during the following year. Ten percent of hemoglobin Bart's was detected 2 months after transplant and this reflects the α-thalassemia trait of the donor.en_HK
dc.languageengen_HK
dc.publisherNature Publishing Group. The Journal's web site is located at http://www.nature.com/bmten_HK
dc.relation.ispartofBone Marrow Transplantationen_HK
dc.subjectCord blood transplantationen_HK
dc.subjectHb Bart's diseaseen_HK
dc.subjectHemoglobin Fen_HK
dc.subjectHLA mismatcheden_HK
dc.subjectImmune thrombocytopeniaen_HK
dc.subject.meshFemaleen_HK
dc.subject.meshFetal Blooden_HK
dc.subject.meshGraft Survivalen_HK
dc.subject.meshHLA-DR Antigensen_HK
dc.subject.meshHematopoietic Stem Cell Transplantation - adverse effects - methodsen_HK
dc.subject.meshHemoglobinopathies - blood - complications - therapyen_HK
dc.subject.meshHemoglobins, Abnormalen_HK
dc.subject.meshHistocompatibility - immunologyen_HK
dc.subject.meshHumansen_HK
dc.subject.meshInfanten_HK
dc.subject.meshNuclear Familyen_HK
dc.subject.meshPurpura, Thrombocytopenic, Idiopathic - drug therapy - etiologyen_HK
dc.subject.meshTransplantation, Homologous - adverse effects - immunology - methodsen_HK
dc.subject.meshalpha-Thalassemia - blood - complications - therapyen_HK
dc.titleSuccessful mismatched sibling cord blood transplant in Hb Bart's diseaseen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0268-3369&volume=28&spage=105&epage=107&date=2001&atitle=Successful+mismatched+sibling+cord+blood+transplant+in+Hb+Bart%27s+diseaseen_HK
dc.identifier.emailChan, GCF:gcfchan@hkucc.hku.hken_HK
dc.identifier.emailChan, V:vnychana@hkucc.hku.hken_HK
dc.identifier.emailLiang, RHS:rliang@hku.hken_HK
dc.identifier.emailLau, YL:lauylung@hkucc.hku.hken_HK
dc.identifier.authorityChan, GCF=rp00431en_HK
dc.identifier.authorityChan, V=rp00320en_HK
dc.identifier.authorityLiang, RHS=rp00345en_HK
dc.identifier.authorityLau, YL=rp00361en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1038/sj.bmt.1703104en_HK
dc.identifier.pmid11498754-
dc.identifier.scopuseid_2-s2.0-0034899954en_HK
dc.identifier.hkuros65285en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0034899954&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume28en_HK
dc.identifier.issue1en_HK
dc.identifier.spage105en_HK
dc.identifier.epage107en_HK
dc.identifier.isiWOS:000170111800017-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridZhou, X=22949652300en_HK
dc.identifier.scopusauthoridHa, SY=7202501115en_HK
dc.identifier.scopusauthoridChan, GCF=16160154400en_HK
dc.identifier.scopusauthoridLuk, CW=7005748744en_HK
dc.identifier.scopusauthoridChan, V=7202654865en_HK
dc.identifier.scopusauthoridHawkins, B=35944486200en_HK
dc.identifier.scopusauthoridLam, YH=7202563903en_HK
dc.identifier.scopusauthoridLiang, RHS=26643224900en_HK
dc.identifier.scopusauthoridLau, YL=7201403380en_HK
dc.identifier.issnl0268-3369-

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