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- Publisher Website: 10.1038/ajg.2009.440
- Scopus: eid_2-s2.0-70350492933
- PMID: 19638962
- WOS: WOS:000270853300030
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Article: Fibrolamellar hepatocellular carcinoma
Title | Fibrolamellar hepatocellular carcinoma | ||||
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Authors | |||||
Keywords | Medical sciences Gastroenterology | ||||
Issue Date | 2009 | ||||
Publisher | Nature Publishing Group. The Journal's web site is located at http://www.nature.com/ajg/index.html | ||||
Citation | American Journal Of Gastroenterology, 2009, v. 104 n. 10, p. 2617-2624 How to Cite? | ||||
Abstract | Fibrolamellar hepatocellular carcinoma (FHLCC) generally occurs in young individuals lacking a background of chronic liver disease and other risk factors for hepatocellular carcinoma. The clinical presentations of FLHCC are generally nonspecific, and the α-fetoprotein level is typically within the normal range in most cases. Imaging studies have a major role in clinical diagnosis, but pathology is the gold standard in confirming diagnosis. Pathological characteristics of FLHCC include the presence of tumor cells with a deeply eosinophilic cytoplasm and macronucleoli surrounded by abundant fibrous bands. The most effective treatment for FLHCC is aggressive surgical resection. This comprehensive literature review gives a full account of the clinical, pathological, and molecular features of FLHCC. | ||||
Persistent Identifier | http://hdl.handle.net/10722/78253 | ||||
ISSN | 2023 Impact Factor: 8.0 2023 SCImago Journal Rankings: 2.391 | ||||
ISI Accession Number ID |
Funding Information: is study was supported in part by the Seed Funding Program for Basic Research of the University of Hong Kong ( grant code 200711159034). | ||||
References | |||||
Grants |
DC Field | Value | Language |
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dc.contributor.author | Liu, S | en_HK |
dc.contributor.author | Chan, KW | en_HK |
dc.contributor.author | Wang, B | en_HK |
dc.contributor.author | Qiao, L | en_HK |
dc.date.accessioned | 2010-09-06T07:40:50Z | - |
dc.date.available | 2010-09-06T07:40:50Z | - |
dc.date.issued | 2009 | en_HK |
dc.identifier.citation | American Journal Of Gastroenterology, 2009, v. 104 n. 10, p. 2617-2624 | en_HK |
dc.identifier.issn | 0002-9270 | en_HK |
dc.identifier.uri | http://hdl.handle.net/10722/78253 | - |
dc.description.abstract | Fibrolamellar hepatocellular carcinoma (FHLCC) generally occurs in young individuals lacking a background of chronic liver disease and other risk factors for hepatocellular carcinoma. The clinical presentations of FLHCC are generally nonspecific, and the α-fetoprotein level is typically within the normal range in most cases. Imaging studies have a major role in clinical diagnosis, but pathology is the gold standard in confirming diagnosis. Pathological characteristics of FLHCC include the presence of tumor cells with a deeply eosinophilic cytoplasm and macronucleoli surrounded by abundant fibrous bands. The most effective treatment for FLHCC is aggressive surgical resection. This comprehensive literature review gives a full account of the clinical, pathological, and molecular features of FLHCC. | en_HK |
dc.language | eng | en_HK |
dc.publisher | Nature Publishing Group. The Journal's web site is located at http://www.nature.com/ajg/index.html | en_HK |
dc.relation.ispartof | American Journal of Gastroenterology | en_HK |
dc.subject | Medical sciences | - |
dc.subject | Gastroenterology | - |
dc.subject.mesh | Carcinoma, Hepatocellular - diagnosis - genetics - pathology - therapy | en_HK |
dc.subject.mesh | Diagnosis, Differential | en_HK |
dc.subject.mesh | Diagnostic Imaging | en_HK |
dc.subject.mesh | Humans | en_HK |
dc.subject.mesh | Liver Neoplasms - diagnosis - genetics - pathology - therapy | en_HK |
dc.subject.mesh | Risk Factors | en_HK |
dc.title | Fibrolamellar hepatocellular carcinoma | en_HK |
dc.type | Article | en_HK |
dc.identifier.openurl | http://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0002-9270&volume=104&issue=10&spage=2617&epage=2624&date=2009&atitle=Fibrolamellar+hepatocellular+carcinoma | en_HK |
dc.identifier.email | Chan, KW: hrmtckw@hku.hk | en_HK |
dc.identifier.email | Qiao, L: lq8688@hotmail.com | en_HK |
dc.identifier.authority | Chan, KW=rp00330 | en_HK |
dc.identifier.authority | Qiao, L=rp00513 | en_HK |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1038/ajg.2009.440 | en_HK |
dc.identifier.pmid | 19638962 | - |
dc.identifier.scopus | eid_2-s2.0-70350492933 | en_HK |
dc.identifier.hkuros | 174357 | en_HK |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-70350492933&selection=ref&src=s&origin=recordpage | en_HK |
dc.identifier.volume | 104 | en_HK |
dc.identifier.issue | 10 | en_HK |
dc.identifier.spage | 2617 | en_HK |
dc.identifier.epage | 2624 | en_HK |
dc.identifier.isi | WOS:000270853300030 | - |
dc.publisher.place | United States | en_HK |
dc.relation.project | Interaction of XIAP and Jagged1 in colon cancer | - |
dc.identifier.scopusauthorid | Liu, S=27171024700 | en_HK |
dc.identifier.scopusauthorid | Chan, KW=16444133100 | en_HK |
dc.identifier.scopusauthorid | Wang, B=8548541700 | en_HK |
dc.identifier.scopusauthorid | Qiao, L=7202151719 | en_HK |
dc.identifier.issnl | 0002-9270 | - |