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- PMID: 12543919
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Article: Granulicatella adiacens and Abiotrophia defectiva bacteraemia characterized by 16S rRNA gene sequencing
Title | Granulicatella adiacens and Abiotrophia defectiva bacteraemia characterized by 16S rRNA gene sequencing |
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Authors | |
Issue Date | 2003 |
Publisher | Society for General Microbiology. The Journal's web site is located at http://jmm.sgmjournals.org |
Citation | Journal Of Medical Microbiology, 2003, v. 52 n. 2, p. 137-140 How to Cite? |
Abstract | Traditionally, the identification, epidemiology and spectrum of clinical diseases caused by Granulicatella adiacens and Abiotrophia defectiva are dependent upon their phenotypic characterization. During a 6-year period (July 1995-June 2001), seven and two α-haemolytic streptococci were identified as G. adiacens and A. defectiva, respectively, by 16S rRNA gene sequencing. Three patients with haematological malignancies and neutropenic fever had primary bacteraemia. Three patients with valvular problems or congenital heart disease had infective endocarditis. A patient with ischemic heart disease and cerebrovascular accident had infected aortic atheroma with dissection. A patient with recurrent pyogenic cholangitis had acute cholangitis and a patient with polypoid cystitis and benign prostatic hypertrophy had acute prostatitis. Four of the nine patients died, including all three with G. adiacens infective endocarditis or infected atheroma. For the seven G. adiacens isolates, the API 20 STREP system successfully identified one and five isolates as G. adiacens with >95% and 80-90% confidence, respectively, whereas the Vitek System (GPI) and ATB Expression system (ID32 STREP) successfully identified none and one isolate as G. adiacens. Of the two A. defectiva isolates, none of the three systems successfully identified either of them as A. defectiva. 16S rRNA gene sequencing is the technique of choice for identifying G. adiacens and A. defectiva, and early surgical intervention should be considered when G. adiacens endocarditis is diagnosed. |
Persistent Identifier | http://hdl.handle.net/10722/79046 |
ISSN | 2023 Impact Factor: 2.4 2023 SCImago Journal Rankings: 0.752 |
ISI Accession Number ID | |
References |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Woo, PCY | en_HK |
dc.contributor.author | Fung, AMY | en_HK |
dc.contributor.author | Lau, SKP | en_HK |
dc.contributor.author | Chan, BYL | en_HK |
dc.contributor.author | Chiu, SK | en_HK |
dc.contributor.author | Teng, JLL | en_HK |
dc.contributor.author | Que, TL | en_HK |
dc.contributor.author | Yung, RWH | en_HK |
dc.contributor.author | Yuen, KY | en_HK |
dc.date.accessioned | 2010-09-06T07:49:56Z | - |
dc.date.available | 2010-09-06T07:49:56Z | - |
dc.date.issued | 2003 | en_HK |
dc.identifier.citation | Journal Of Medical Microbiology, 2003, v. 52 n. 2, p. 137-140 | en_HK |
dc.identifier.issn | 0022-2615 | en_HK |
dc.identifier.uri | http://hdl.handle.net/10722/79046 | - |
dc.description.abstract | Traditionally, the identification, epidemiology and spectrum of clinical diseases caused by Granulicatella adiacens and Abiotrophia defectiva are dependent upon their phenotypic characterization. During a 6-year period (July 1995-June 2001), seven and two α-haemolytic streptococci were identified as G. adiacens and A. defectiva, respectively, by 16S rRNA gene sequencing. Three patients with haematological malignancies and neutropenic fever had primary bacteraemia. Three patients with valvular problems or congenital heart disease had infective endocarditis. A patient with ischemic heart disease and cerebrovascular accident had infected aortic atheroma with dissection. A patient with recurrent pyogenic cholangitis had acute cholangitis and a patient with polypoid cystitis and benign prostatic hypertrophy had acute prostatitis. Four of the nine patients died, including all three with G. adiacens infective endocarditis or infected atheroma. For the seven G. adiacens isolates, the API 20 STREP system successfully identified one and five isolates as G. adiacens with >95% and 80-90% confidence, respectively, whereas the Vitek System (GPI) and ATB Expression system (ID32 STREP) successfully identified none and one isolate as G. adiacens. Of the two A. defectiva isolates, none of the three systems successfully identified either of them as A. defectiva. 16S rRNA gene sequencing is the technique of choice for identifying G. adiacens and A. defectiva, and early surgical intervention should be considered when G. adiacens endocarditis is diagnosed. | en_HK |
dc.language | eng | en_HK |
dc.publisher | Society for General Microbiology. The Journal's web site is located at http://jmm.sgmjournals.org | en_HK |
dc.relation.ispartof | Journal of Medical Microbiology | en_HK |
dc.subject.mesh | Adolescent | en_HK |
dc.subject.mesh | Adult | en_HK |
dc.subject.mesh | Aged | en_HK |
dc.subject.mesh | Aged, 80 and over | en_HK |
dc.subject.mesh | Bacteremia - diagnosis - microbiology | en_HK |
dc.subject.mesh | Base Sequence | en_HK |
dc.subject.mesh | DNA, Ribosomal - chemistry | en_HK |
dc.subject.mesh | Endocarditis, Bacterial - diagnosis - microbiology | en_HK |
dc.subject.mesh | Female | en_HK |
dc.subject.mesh | Genes, Bacterial | en_HK |
dc.subject.mesh | Humans | en_HK |
dc.subject.mesh | Male | en_HK |
dc.subject.mesh | Middle Aged | en_HK |
dc.subject.mesh | Molecular Sequence Data | en_HK |
dc.subject.mesh | Phenotype | en_HK |
dc.subject.mesh | Phylogeny | en_HK |
dc.subject.mesh | Polymerase Chain Reaction - methods | en_HK |
dc.subject.mesh | RNA, Ribosomal, 16S - genetics | en_HK |
dc.subject.mesh | Sensitivity and Specificity | en_HK |
dc.subject.mesh | Streptococcal Infections - diagnosis - microbiology | en_HK |
dc.subject.mesh | Streptococcus - classification - genetics - isolation & purification | en_HK |
dc.title | Granulicatella adiacens and Abiotrophia defectiva bacteraemia characterized by 16S rRNA gene sequencing | en_HK |
dc.type | Article | en_HK |
dc.identifier.openurl | http://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0022-2615&volume=52&issue=2&spage=137&epage=140&date=2003&atitle=Granulicatella+adiacens+and+Abiotrophia+defectiva+bacteraemia+characterized+by+16S+rRNA+gene+sequencing | en_HK |
dc.identifier.email | Woo, PCY:pcywoo@hkucc.hku.hk | en_HK |
dc.identifier.email | Lau, SKP:skplau@hkucc.hku.hk | en_HK |
dc.identifier.email | Teng, JLL:llteng@hku.hk | en_HK |
dc.identifier.email | Yuen, KY:kyyuen@hkucc.hku.hk | en_HK |
dc.identifier.authority | Woo, PCY=rp00430 | en_HK |
dc.identifier.authority | Lau, SKP=rp00486 | en_HK |
dc.identifier.authority | Teng, JLL=rp00277 | en_HK |
dc.identifier.authority | Yuen, KY=rp00366 | en_HK |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1099/jmm.0.04950-0 | en_HK |
dc.identifier.pmid | 12543919 | - |
dc.identifier.scopus | eid_2-s2.0-0037320382 | en_HK |
dc.identifier.hkuros | 116817 | en_HK |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-0037320382&selection=ref&src=s&origin=recordpage | en_HK |
dc.identifier.volume | 52 | en_HK |
dc.identifier.issue | 2 | en_HK |
dc.identifier.spage | 137 | en_HK |
dc.identifier.epage | 140 | en_HK |
dc.identifier.isi | WOS:000181168900006 | - |
dc.publisher.place | United Kingdom | en_HK |
dc.identifier.scopusauthorid | Woo, PCY=7201801340 | en_HK |
dc.identifier.scopusauthorid | Fung, AMY=7101926801 | en_HK |
dc.identifier.scopusauthorid | Lau, SKP=7401596211 | en_HK |
dc.identifier.scopusauthorid | Chan, BYL=7201530670 | en_HK |
dc.identifier.scopusauthorid | Chiu, SK=7202291644 | en_HK |
dc.identifier.scopusauthorid | Teng, JLL=7202560229 | en_HK |
dc.identifier.scopusauthorid | Que, TL=7003786628 | en_HK |
dc.identifier.scopusauthorid | Yung, RWH=7005594277 | en_HK |
dc.identifier.scopusauthorid | Yuen, KY=36078079100 | en_HK |
dc.identifier.issnl | 0022-2615 | - |