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Article: Lymphocyte DNA damage in bus manufacturing workers

TitleLymphocyte DNA damage in bus manufacturing workers
Authors
KeywordsBenzene
Bus manufacturing worker
Comet assay
DNA damage
Smoking
Welder
Issue Date2001
PublisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/gentox
Citation
Mutation Research - Genetic Toxicology And Environmental Mutagenesis, 2001, v. 491 n. 1-2, p. 173-181 How to Cite?
AbstractTo study the effect of occupational exposure, smoking, and drinking on lymphocyte DNA damage in bus manufacturing workers, 346 employees (106 women and 240 men) from six job categories (welders, mechanics, painters, and assembling, auxiliary and managerial workers) in a bus manufacturing factory in Guangzhou were included. Significant differences of tail moment among the six job categories were found (P = 0.003) with adjustment for age and gender. Smoking increased tail moment significantly (3.14 (2.89-3.40) versus 2.79 μm (2.63-2.97), P = 0.023). Analysis of covariance showed that occupational exposure (P = 0.001) and smoking (P = 0.019) had significant effect on tail moment after adjusting for all factors, whereas age and gender had no effect on DNA damage. Stratified analysis showed that painters (P = 0.002), auxiliary workers (P = 0.011), and mechanics (P = 0.044) had larger tail moments than managerial workers after adjusting for age, gender, smoking, and drinking. © 2001 Elsevier Science B.V.
Persistent Identifierhttp://hdl.handle.net/10722/86631
ISSN
2023 Impact Factor: 2.3
2023 SCImago Journal Rankings: 0.575
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorZhu, CQen_HK
dc.contributor.authorLam, THen_HK
dc.contributor.authorJiang, CQen_HK
dc.date.accessioned2010-09-06T09:19:24Z-
dc.date.available2010-09-06T09:19:24Z-
dc.date.issued2001en_HK
dc.identifier.citationMutation Research - Genetic Toxicology And Environmental Mutagenesis, 2001, v. 491 n. 1-2, p. 173-181en_HK
dc.identifier.issn1383-5718en_HK
dc.identifier.urihttp://hdl.handle.net/10722/86631-
dc.description.abstractTo study the effect of occupational exposure, smoking, and drinking on lymphocyte DNA damage in bus manufacturing workers, 346 employees (106 women and 240 men) from six job categories (welders, mechanics, painters, and assembling, auxiliary and managerial workers) in a bus manufacturing factory in Guangzhou were included. Significant differences of tail moment among the six job categories were found (P = 0.003) with adjustment for age and gender. Smoking increased tail moment significantly (3.14 (2.89-3.40) versus 2.79 μm (2.63-2.97), P = 0.023). Analysis of covariance showed that occupational exposure (P = 0.001) and smoking (P = 0.019) had significant effect on tail moment after adjusting for all factors, whereas age and gender had no effect on DNA damage. Stratified analysis showed that painters (P = 0.002), auxiliary workers (P = 0.011), and mechanics (P = 0.044) had larger tail moments than managerial workers after adjusting for age, gender, smoking, and drinking. © 2001 Elsevier Science B.V.en_HK
dc.languageengen_HK
dc.publisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/gentoxen_HK
dc.relation.ispartofMutation Research - Genetic Toxicology and Environmental Mutagenesisen_HK
dc.rightsMutation Research. Copyright © Elsevier BV.en_HK
dc.subjectBenzene-
dc.subjectBus manufacturing worker-
dc.subjectComet assay-
dc.subjectDNA damage-
dc.subjectSmoking-
dc.subjectWelder-
dc.subject.meshComet Assayen_HK
dc.subject.meshDNA Damageen_HK
dc.subject.meshFemaleen_HK
dc.subject.meshHumansen_HK
dc.subject.meshLymphocytes - ultrastructureen_HK
dc.subject.meshMaleen_HK
dc.subject.meshOccupational Exposureen_HK
dc.titleLymphocyte DNA damage in bus manufacturing workersen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0027-5107&volume=491&spage=173&epage=181&date=2001&atitle=Lymphocyte+DNA+damage+in+bus+manufacturing+workersen_HK
dc.identifier.emailLam, TH:hrmrlth@hkucc.hku.hken_HK
dc.identifier.authorityLam, TH=rp00326en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/S1383-5718(01)00141-3en_HK
dc.identifier.pmid11287310en_HK
dc.identifier.scopuseid_2-s2.0-0035810299en_HK
dc.identifier.hkuros56820en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0035810299&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume491en_HK
dc.identifier.issue1-2en_HK
dc.identifier.spage173en_HK
dc.identifier.epage181en_HK
dc.identifier.isiWOS:000168099100020-
dc.publisher.placeNetherlandsen_HK
dc.identifier.scopusauthoridZhu, CQ=8537385600en_HK
dc.identifier.scopusauthoridLam, TH=7202522876en_HK
dc.identifier.scopusauthoridJiang, CQ=10639500500en_HK
dc.identifier.issnl1383-5718-

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