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- Publisher Website: 10.1055/s-2006-924259
- Scopus: eid_2-s2.0-33746716908
- PMID: 16868888
- WOS: WOS:000239359500003
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Article: Association of smoking with increasing vascular involvement in type 2 diabetic Chinese patients
Title | Association of smoking with increasing vascular involvement in type 2 diabetic Chinese patients |
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Authors | |
Keywords | Cardiovascular disease Metabolic syndrome Middle cerebral artery stenosis Peripheral vascular disease Retinopathy Smoking |
Issue Date | 2006 |
Publisher | Johann Ambrosius Barth Verlag in Medizinverlage Heidelberg GmbH & Co KG. The Journal's web site is located at http://www.thieme.de/eced |
Citation | Experimental And Clinical Endocrinology And Diabetes, 2006, v. 114 n. 6, p. 301-305 How to Cite? |
Abstract | Purpose: To identify the relationship between smoking and the metabolic profile and existing vascular disease in Chinese type 2 diabetic patients. Methods: 1710 diabetic patients were screened for complications, and biochemical and anthropometric vascular risk factors. As most smokers were male, differences were only compared between male current (n = 196) and never smoking patients (n = 300). Results: The smokers had higher glycosylated haemoglobin levels (8.2 ± 2.0 vs. 7.6 ± 1 8%, p < 0.001) than never smokers, despite a greater proportion receiving hypoglycaemic agents (87.5 vs. 79.6%, p = 0.003). Male smokers compared to never smokers had lower HDL-cholesterol levels (1.12 ± 0.31 vs. 1.20 ± 0.30 mmol/L, p = 0.006), and elevated albumin-to-creatinine ratio (3.57 [2.68-4.75] vs. 2.47 [1.99-3.05] mg/mmol, p = 0.040). However, diastolic blood pressure was lower in the smoking group (78 ± 12 vs. 82 ± 12 mmHg, p = 0.001) even though they received less blood pressure-lowering treatments (23.8 vs. 33.2%, p = 0.034). The prevalence of peripheral vascular disease was increased in the diabetic patients who smoked compared to nonsmokers (7.1 vs. 2.8%, p = 0.039). Conclusions: Smoking was associated with a more adverse metabolic profile and peripheral vascular disease. As mainland China undergoes rapid modernisation and urbanisation, the observed effects of smoking means tobacco control becomes increasingly important to prevent or minimise potential health impacts and chronic disease. © J. A. Barth Verlag in Georg Thieme Verlag KG. |
Persistent Identifier | http://hdl.handle.net/10722/86968 |
ISSN | 2023 Impact Factor: 1.6 2023 SCImago Journal Rankings: 0.493 |
ISI Accession Number ID | |
References |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Thomas, GN | en_HK |
dc.contributor.author | Tomlinson, B | en_HK |
dc.contributor.author | McGhee, SM | en_HK |
dc.contributor.author | Lam, TH | en_HK |
dc.contributor.author | Abdullah, ASM | en_HK |
dc.contributor.author | Yeung, VTF | en_HK |
dc.contributor.author | Wong, KS | en_HK |
dc.contributor.author | Chan, JCN | en_HK |
dc.date.accessioned | 2010-09-06T09:23:33Z | - |
dc.date.available | 2010-09-06T09:23:33Z | - |
dc.date.issued | 2006 | en_HK |
dc.identifier.citation | Experimental And Clinical Endocrinology And Diabetes, 2006, v. 114 n. 6, p. 301-305 | en_HK |
dc.identifier.issn | 0947-7349 | en_HK |
dc.identifier.uri | http://hdl.handle.net/10722/86968 | - |
dc.description.abstract | Purpose: To identify the relationship between smoking and the metabolic profile and existing vascular disease in Chinese type 2 diabetic patients. Methods: 1710 diabetic patients were screened for complications, and biochemical and anthropometric vascular risk factors. As most smokers were male, differences were only compared between male current (n = 196) and never smoking patients (n = 300). Results: The smokers had higher glycosylated haemoglobin levels (8.2 ± 2.0 vs. 7.6 ± 1 8%, p < 0.001) than never smokers, despite a greater proportion receiving hypoglycaemic agents (87.5 vs. 79.6%, p = 0.003). Male smokers compared to never smokers had lower HDL-cholesterol levels (1.12 ± 0.31 vs. 1.20 ± 0.30 mmol/L, p = 0.006), and elevated albumin-to-creatinine ratio (3.57 [2.68-4.75] vs. 2.47 [1.99-3.05] mg/mmol, p = 0.040). However, diastolic blood pressure was lower in the smoking group (78 ± 12 vs. 82 ± 12 mmHg, p = 0.001) even though they received less blood pressure-lowering treatments (23.8 vs. 33.2%, p = 0.034). The prevalence of peripheral vascular disease was increased in the diabetic patients who smoked compared to nonsmokers (7.1 vs. 2.8%, p = 0.039). Conclusions: Smoking was associated with a more adverse metabolic profile and peripheral vascular disease. As mainland China undergoes rapid modernisation and urbanisation, the observed effects of smoking means tobacco control becomes increasingly important to prevent or minimise potential health impacts and chronic disease. © J. A. Barth Verlag in Georg Thieme Verlag KG. | en_HK |
dc.language | eng | en_HK |
dc.publisher | Johann Ambrosius Barth Verlag in Medizinverlage Heidelberg GmbH & Co KG. The Journal's web site is located at http://www.thieme.de/eced | en_HK |
dc.relation.ispartof | Experimental and Clinical Endocrinology and Diabetes | en_HK |
dc.subject | Cardiovascular disease | - |
dc.subject | Metabolic syndrome | - |
dc.subject | Middle cerebral artery stenosis | - |
dc.subject | Peripheral vascular disease | - |
dc.subject | Retinopathy | - |
dc.subject | Smoking | - |
dc.subject.mesh | Adult | en_HK |
dc.subject.mesh | Aged | en_HK |
dc.subject.mesh | Asian Continental Ancestry Group | en_HK |
dc.subject.mesh | Cross-Sectional Studies | en_HK |
dc.subject.mesh | Diabetes Mellitus, Type 2 - blood - epidemiology | en_HK |
dc.subject.mesh | Diabetic Angiopathies - epidemiology | en_HK |
dc.subject.mesh | Female | en_HK |
dc.subject.mesh | Humans | en_HK |
dc.subject.mesh | Male | en_HK |
dc.subject.mesh | Middle Aged | en_HK |
dc.subject.mesh | Risk Factors | en_HK |
dc.subject.mesh | Smoking - adverse effects | en_HK |
dc.title | Association of smoking with increasing vascular involvement in type 2 diabetic Chinese patients | en_HK |
dc.type | Article | en_HK |
dc.identifier.openurl | http://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0947-7349&volume=114&spage=301&epage=305&date=2006&atitle=Association+of+smoking+with+increasing+vascular+involvement+in+type+2+diabetic+Chinese+patients | en_HK |
dc.identifier.email | McGhee, SM:smmcghee@hkucc.hku.hk | en_HK |
dc.identifier.email | Lam, TH:hrmrlth@hkucc.hku.hk | en_HK |
dc.identifier.authority | McGhee, SM=rp00393 | en_HK |
dc.identifier.authority | Lam, TH=rp00326 | en_HK |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1055/s-2006-924259 | en_HK |
dc.identifier.pmid | 16868888 | - |
dc.identifier.scopus | eid_2-s2.0-33746716908 | en_HK |
dc.identifier.hkuros | 121842 | en_HK |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-33746716908&selection=ref&src=s&origin=recordpage | en_HK |
dc.identifier.volume | 114 | en_HK |
dc.identifier.issue | 6 | en_HK |
dc.identifier.spage | 301 | en_HK |
dc.identifier.epage | 305 | en_HK |
dc.identifier.isi | WOS:000239359500003 | - |
dc.publisher.place | Germany | en_HK |
dc.identifier.scopusauthorid | Thomas, GN=35465269900 | en_HK |
dc.identifier.scopusauthorid | Tomlinson, B=16423466900 | en_HK |
dc.identifier.scopusauthorid | McGhee, SM=7003288588 | en_HK |
dc.identifier.scopusauthorid | Lam, TH=7202522876 | en_HK |
dc.identifier.scopusauthorid | Abdullah, ASM=7102085860 | en_HK |
dc.identifier.scopusauthorid | Yeung, VTF=35892061300 | en_HK |
dc.identifier.scopusauthorid | Wong, KS=7404759405 | en_HK |
dc.identifier.scopusauthorid | Chan, JCN=7403287000 | en_HK |
dc.identifier.issnl | 0947-7349 | - |