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Article: Role of serial tumor markers in the surveillance for recurrence in endometrial cancer

TitleRole of serial tumor markers in the surveillance for recurrence in endometrial cancer
Authors
Lo, SSTKhoo, USCheng, DKLNg, TYWong, LCNgan, HYS
KeywordsCA125
CA15.3
CA19.9
Endometrial cancer
Recurrence
Issue Date1999
PublisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/cdp
Citation
Cancer Detection And Prevention, 1999, v. 23 n. 5, p. 397-400 How to Cite?
DOI: http://dx.doi.org/10.1046/j.1525-1500.1999.99043.x
AbstractThe aim of this study is to evaluate the usefulness of tumor markers in the follow-up of patients with endometrial cancer. The sera of 23 patients with elevated pretreatment CA125, CA15.3, and CA19.9 were collected at each follow-up visit and analyzed. Eleven patients had normal posttreatment levels and none of them developed recurrence. Twelve patients had one or more increased tumor markers, 7 (58.3%) of them developed recurrence. Among these seven patients, six had CA 125 elevated by at least 10-fold and one had elevated CA 19.9. The median lead time between elevation of tumor markers and clinical evidence of recurrence was 6 months. Hence posttreatment elevation of CA 125 is a useful predictor for recurrence in patients with elevated pretreatment levels.
Persistent Identifierhttp://hdl.handle.net/10722/87134
ISSN
0361-090X
2011 Impact Factor: 2.522
ISI Accession Number ID
WOS:000082300700005

 

DC FieldValueLanguage
dc.contributor.authorLo, SSTen_HK
dc.contributor.authorKhoo, USen_HK
dc.contributor.authorCheng, DKLen_HK
dc.contributor.authorNg, TYen_HK
dc.contributor.authorWong, LCen_HK
dc.contributor.authorNgan, HYSen_HK
dc.date.accessioned2010-09-06T09:25:46Z-
dc.date.available2010-09-06T09:25:46Z-
dc.date.issued1999en_HK
dc.identifier.citationCancer Detection And Prevention, 1999, v. 23 n. 5, p. 397-400en_HK
dc.identifier.issn0361-090Xen_HK
dc.identifier.urihttp://hdl.handle.net/10722/87134-
dc.description.abstractThe aim of this study is to evaluate the usefulness of tumor markers in the follow-up of patients with endometrial cancer. The sera of 23 patients with elevated pretreatment CA125, CA15.3, and CA19.9 were collected at each follow-up visit and analyzed. Eleven patients had normal posttreatment levels and none of them developed recurrence. Twelve patients had one or more increased tumor markers, 7 (58.3%) of them developed recurrence. Among these seven patients, six had CA 125 elevated by at least 10-fold and one had elevated CA 19.9. The median lead time between elevation of tumor markers and clinical evidence of recurrence was 6 months. Hence posttreatment elevation of CA 125 is a useful predictor for recurrence in patients with elevated pretreatment levels.en_HK
dc.languageengen_HK
dc.publisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/cdpen_HK
dc.relation.ispartofCancer Detection and Preventionen_HK
dc.rightsCancer Detection and Prevention. Copyright © Elsevier Inc.en_HK
dc.subjectCA125en_HK
dc.subjectCA15.3en_HK
dc.subjectCA19.9en_HK
dc.subjectEndometrial canceren_HK
dc.subjectRecurrenceen_HK
dc.subject.meshCA-125 Antigen - blooden_HK
dc.subject.meshCA-19-9 Antigen - blooden_HK
dc.subject.meshEndometrial Neoplasms - diagnosis - surgery - therapyen_HK
dc.subject.meshFemaleen_HK
dc.subject.meshHumansen_HK
dc.subject.meshMucin-1 - blooden_HK
dc.subject.meshPrognosisen_HK
dc.subject.meshRecurrenceen_HK
dc.subject.meshTumor Markers, Biologicalen_HK
dc.titleRole of serial tumor markers in the surveillance for recurrence in endometrial canceren_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0361-090X&volume=23&spage=&epage=&date=1999&atitle=Role+of+serial+tumor+markers+in+the+surveillance+for+recurrence+in+endometrial+canceren_HK
dc.identifier.emailKhoo, US:uskhoo@hkucc.hku.hken_HK
dc.identifier.emailNgan, HYS:hysngan@hkucc.hku.hken_HK
dc.identifier.authorityKhoo, US=rp00362en_HK
dc.identifier.authorityNgan, HYS=rp00346en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1046/j.1525-1500.1999.99043.xen_HK
dc.identifier.pmid10468891en_HK
dc.identifier.scopuseid_2-s2.0-0032828543en_HK
dc.identifier.hkuros42779en_HK
dc.identifier.volume23en_HK
dc.identifier.issue5en_HK
dc.identifier.spage397en_HK
dc.identifier.epage400en_HK
dc.identifier.isiWOS:000082300700005-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridLo, SST=15518872700en_HK
dc.identifier.scopusauthoridKhoo, US=7004195799en_HK
dc.identifier.scopusauthoridCheng, DKL=7402806161en_HK
dc.identifier.scopusauthoridNg, TY=7402229853en_HK
dc.identifier.scopusauthoridWong, LC=7402092003en_HK
dc.identifier.scopusauthoridNgan, HYS=34571944100en_HK
dc.identifier.issnl0361-090X-

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