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Article: Tyrosinase inhibitors from paper mulberry (Broussonetia papyrifera)
Title | Tyrosinase inhibitors from paper mulberry (Broussonetia papyrifera) |
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Authors | |
Keywords | Broussonetia papyrifera Chalcone Flavonol Tyrosinase inhibition |
Issue Date | 2008 |
Publisher | Elsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/foodchem |
Citation | Food Chemistry, 2008, v. 106 n. 2, p. 529-535 How to Cite? |
Abstract | Fractionation of a chloroform-soluble extract from twigs of Broussonetia papyrifera, led to the isolation of one new compound, 3,5,7,4′-tetrahydroxy-3′-(2-hydroxy-3-methylbut-3-enyl)flavone (1), and 10 known compounds, uralenol (2), quercetin (3), isolicoflavonol (4), papyriflavonol A (5), broussoflavonol F (6), 5,7,3′,5′-tetrahydroxyflavanone (7), luteolin (8), isoliquiritigenin (9), broussochalcone A (10) and 5,7,3′,4′-tetrahydroxy-3-methoxyflavone (11). Their structures were identified by interpretation of MS, 1H NMR, 13C NMR, HMQC and HMBC data. Their inhibitory activities on mushroom tyrosinase using l-tyrosine as substrate were investigated and the IC 50 values of 3,5,7,4′-tetrahydroxy-3′-(2-hydroxy-3-methylbut-3-enyl)flavone, uralenol, quercetin and broussoflavonol F were found to be 96.6, 49.5, 57.8, and 82.3 μM, respectively, better than arbutin, a well-known tyrosinase inhibitor. © 2007 Elsevier Ltd. All rights reserved. |
Persistent Identifier | http://hdl.handle.net/10722/89211 |
ISSN | 2023 Impact Factor: 8.5 2023 SCImago Journal Rankings: 1.745 |
ISI Accession Number ID | |
References |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Zheng, ZP | en_HK |
dc.contributor.author | Cheng, KW | en_HK |
dc.contributor.author | Chao, J | en_HK |
dc.contributor.author | Wu, J | en_HK |
dc.contributor.author | Wang, M | en_HK |
dc.date.accessioned | 2010-09-06T09:53:57Z | - |
dc.date.available | 2010-09-06T09:53:57Z | - |
dc.date.issued | 2008 | en_HK |
dc.identifier.citation | Food Chemistry, 2008, v. 106 n. 2, p. 529-535 | en_HK |
dc.identifier.issn | 0308-8146 | en_HK |
dc.identifier.uri | http://hdl.handle.net/10722/89211 | - |
dc.description.abstract | Fractionation of a chloroform-soluble extract from twigs of Broussonetia papyrifera, led to the isolation of one new compound, 3,5,7,4′-tetrahydroxy-3′-(2-hydroxy-3-methylbut-3-enyl)flavone (1), and 10 known compounds, uralenol (2), quercetin (3), isolicoflavonol (4), papyriflavonol A (5), broussoflavonol F (6), 5,7,3′,5′-tetrahydroxyflavanone (7), luteolin (8), isoliquiritigenin (9), broussochalcone A (10) and 5,7,3′,4′-tetrahydroxy-3-methoxyflavone (11). Their structures were identified by interpretation of MS, 1H NMR, 13C NMR, HMQC and HMBC data. Their inhibitory activities on mushroom tyrosinase using l-tyrosine as substrate were investigated and the IC 50 values of 3,5,7,4′-tetrahydroxy-3′-(2-hydroxy-3-methylbut-3-enyl)flavone, uralenol, quercetin and broussoflavonol F were found to be 96.6, 49.5, 57.8, and 82.3 μM, respectively, better than arbutin, a well-known tyrosinase inhibitor. © 2007 Elsevier Ltd. All rights reserved. | en_HK |
dc.language | eng | en_HK |
dc.publisher | Elsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/foodchem | en_HK |
dc.relation.ispartof | Food Chemistry | en_HK |
dc.rights | Food Chemistry . Copyright © Elsevier BV. | en_HK |
dc.subject | Broussonetia papyrifera | en_HK |
dc.subject | Chalcone | en_HK |
dc.subject | Flavonol | en_HK |
dc.subject | Tyrosinase inhibition | en_HK |
dc.title | Tyrosinase inhibitors from paper mulberry (Broussonetia papyrifera) | en_HK |
dc.type | Article | en_HK |
dc.identifier.openurl | http://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0308-8146&volume=106&issue=2&spage=529&epage=535&date=2008&atitle=Tyrosinase+inhibitors+from+paper+mulberry+(Broussonetia+papyrifera) | en_HK |
dc.identifier.email | Wang, M: mfwang@hku.hk | en_HK |
dc.identifier.authority | Wang, M=rp00800 | en_HK |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1016/j.foodchem.2007.06.037 | en_HK |
dc.identifier.scopus | eid_2-s2.0-34548255352 | en_HK |
dc.identifier.hkuros | 142339 | en_HK |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-34548255352&selection=ref&src=s&origin=recordpage | en_HK |
dc.identifier.volume | 106 | en_HK |
dc.identifier.issue | 2 | en_HK |
dc.identifier.spage | 529 | en_HK |
dc.identifier.epage | 535 | en_HK |
dc.identifier.isi | WOS:000250038400013 | - |
dc.publisher.place | Netherlands | en_HK |
dc.identifier.scopusauthorid | Zheng, ZP=8451746600 | en_HK |
dc.identifier.scopusauthorid | Cheng, KW=12141247000 | en_HK |
dc.identifier.scopusauthorid | Chao, J=24558959000 | en_HK |
dc.identifier.scopusauthorid | Wu, J=8298828200 | en_HK |
dc.identifier.scopusauthorid | Wang, M=7406691844 | en_HK |
dc.identifier.issnl | 0308-8146 | - |