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- Publisher Website: 10.1093/qjmed/93.3.163
- Scopus: eid_2-s2.0-0034051149
- PMID: 10751235
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Article: Diastolic blood pressure is related to urinary sodium excretion in hypertensive Chinese patients
Title | Diastolic blood pressure is related to urinary sodium excretion in hypertensive Chinese patients |
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Authors | |
Keywords | Chemicals And Cas Registry Numbers |
Issue Date | 2000 |
Publisher | Oxford University Press. The Journal's web site is located at http://qjmed.oxfordjournals.org/ |
Citation | Qjm - Monthly Journal Of The Association Of Physicians, 2000, v. 93 n. 3, p. 163-168 How to Cite? |
Abstract | We studied 70 Hong Kong Chinese patients with untreated hypertension and 47 normotensive controls. Blood pressure measurements and 24-h urine collection were performed for each patient, and were repeated 12 weeks later in 14 hypertensive patients who remained untreated. Twenty-two hypertensive patients underwent ambulatory blood pressure monitoring. The primary hypothesis tested was a correlation between diastolic blood pressure and 24-h urinary sodium excretion. In the hypertensive patients, diastolic blood pressure correlated with 24-h urinary sodium excretion (r = 0.41, p < 0.001), even after adjustment for age, gender, body mass index, ethanol intake and season (r = 0.34, p = 0.02). In normotensive controls, diastolic blood pressure did not correlate with sodium excretion (r = 0.21, p = 0.16). A correlation between diastolic blood pressure and sodium excretion was also observed in the patients who underwent ambulatory blood pressure monitoring (r = 0.47, p = 0.026), and in repeat measurements in untreated patients (r = 0.60, p = 0.02). Systolic blood pressure did not correlate with sodium excretion, although it increased with patient age (0.6 ± 0.1 mmHg/year, p < 0.001). In a multiple regression analysis with diastolic blood pressure as the dependent variable, the regression coefficient was 0.06 ± 0.02 mmHg/mmol Na. The regression coefficients for ambulatory diastolic blood pressure and diastolic pressure repeated at 12 weeks were 0.07 ± 0.03 and 0.09 ± 0.04 mmHg/mmol Na, respectively. Urinary sodium excretion was related to diastolic blood pressure in our hypertensive patients, accounting for 17% of the variance of diastolic blood pressure. |
Persistent Identifier | http://hdl.handle.net/10722/91449 |
ISSN | 2023 Impact Factor: 7.3 2023 SCImago Journal Rankings: 0.626 |
ISI Accession Number ID | |
References |
DC Field | Value | Language |
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dc.contributor.author | Cheung, BMY | en_HK |
dc.contributor.author | Ho, SPC | en_HK |
dc.contributor.author | Cheung, AHK | en_HK |
dc.contributor.author | Lau, CP | en_HK |
dc.date.accessioned | 2010-09-17T10:19:35Z | - |
dc.date.available | 2010-09-17T10:19:35Z | - |
dc.date.issued | 2000 | en_HK |
dc.identifier.citation | Qjm - Monthly Journal Of The Association Of Physicians, 2000, v. 93 n. 3, p. 163-168 | en_HK |
dc.identifier.issn | 1460-2725 | en_HK |
dc.identifier.uri | http://hdl.handle.net/10722/91449 | - |
dc.description.abstract | We studied 70 Hong Kong Chinese patients with untreated hypertension and 47 normotensive controls. Blood pressure measurements and 24-h urine collection were performed for each patient, and were repeated 12 weeks later in 14 hypertensive patients who remained untreated. Twenty-two hypertensive patients underwent ambulatory blood pressure monitoring. The primary hypothesis tested was a correlation between diastolic blood pressure and 24-h urinary sodium excretion. In the hypertensive patients, diastolic blood pressure correlated with 24-h urinary sodium excretion (r = 0.41, p < 0.001), even after adjustment for age, gender, body mass index, ethanol intake and season (r = 0.34, p = 0.02). In normotensive controls, diastolic blood pressure did not correlate with sodium excretion (r = 0.21, p = 0.16). A correlation between diastolic blood pressure and sodium excretion was also observed in the patients who underwent ambulatory blood pressure monitoring (r = 0.47, p = 0.026), and in repeat measurements in untreated patients (r = 0.60, p = 0.02). Systolic blood pressure did not correlate with sodium excretion, although it increased with patient age (0.6 ± 0.1 mmHg/year, p < 0.001). In a multiple regression analysis with diastolic blood pressure as the dependent variable, the regression coefficient was 0.06 ± 0.02 mmHg/mmol Na. The regression coefficients for ambulatory diastolic blood pressure and diastolic pressure repeated at 12 weeks were 0.07 ± 0.03 and 0.09 ± 0.04 mmHg/mmol Na, respectively. Urinary sodium excretion was related to diastolic blood pressure in our hypertensive patients, accounting for 17% of the variance of diastolic blood pressure. | en_HK |
dc.language | eng | en_HK |
dc.publisher | Oxford University Press. The Journal's web site is located at http://qjmed.oxfordjournals.org/ | en_HK |
dc.relation.ispartof | QJM - Monthly Journal of the Association of Physicians | en_HK |
dc.subject | Chemicals And Cas Registry Numbers | en_HK |
dc.subject.mesh | Adolescent | en_HK |
dc.subject.mesh | Adult | en_HK |
dc.subject.mesh | Age Factors | en_HK |
dc.subject.mesh | Aged | en_HK |
dc.subject.mesh | Alcohol Drinking | en_HK |
dc.subject.mesh | Blood Pressure - physiology | en_HK |
dc.subject.mesh | Body Mass Index | en_HK |
dc.subject.mesh | Case-Control Studies | en_HK |
dc.subject.mesh | China - ethnology | en_HK |
dc.subject.mesh | Creatinine - urine | en_HK |
dc.subject.mesh | Female | en_HK |
dc.subject.mesh | Hong Kong | en_HK |
dc.subject.mesh | Humans | en_HK |
dc.subject.mesh | Hypertension - ethnology - metabolism - physiopathology | en_HK |
dc.subject.mesh | Male | en_HK |
dc.subject.mesh | Middle Aged | en_HK |
dc.subject.mesh | Potassium - urine | en_HK |
dc.subject.mesh | Prospective Studies | en_HK |
dc.subject.mesh | Regression Analysis | en_HK |
dc.subject.mesh | Sex Factors | en_HK |
dc.subject.mesh | Sodium - urine | en_HK |
dc.subject.mesh | Sodium Chloride, Dietary - adverse effects | en_HK |
dc.title | Diastolic blood pressure is related to urinary sodium excretion in hypertensive Chinese patients | en_HK |
dc.type | Article | en_HK |
dc.identifier.email | Cheung, BMY:mycheung@hku.hk | en_HK |
dc.identifier.authority | Cheung, BMY=rp01321 | en_HK |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1093/qjmed/93.3.163 | - |
dc.identifier.pmid | 10751235 | - |
dc.identifier.scopus | eid_2-s2.0-0034051149 | en_HK |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-0034051149&selection=ref&src=s&origin=recordpage | en_HK |
dc.identifier.volume | 93 | en_HK |
dc.identifier.issue | 3 | en_HK |
dc.identifier.spage | 163 | en_HK |
dc.identifier.epage | 168 | en_HK |
dc.identifier.isi | WOS:000085753400005 | - |
dc.publisher.place | United Kingdom | en_HK |
dc.identifier.scopusauthorid | Cheung, BMY=7103294806 | en_HK |
dc.identifier.scopusauthorid | Ho, SPC=12794365900 | en_HK |
dc.identifier.scopusauthorid | Cheung, AHK=12795914100 | en_HK |
dc.identifier.scopusauthorid | Lau, CP=7401968501 | en_HK |
dc.identifier.issnl | 1460-2393 | - |