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Browsing by Author Lai, PL
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Showing results 1 to 12 of 12
Title
Author(s)
Issue Date
Views
Ciliary protein Kif7 regulates Gli and Ezh2 for initiating the neuronal differentiation of enteric neural crest cells during development
Journal:
Science Advances
Lai, PL
LI, Z
ZHOU, T
Leung, OW
Lau, ST
Lui, NC
WONG, YM
Sham, PC
Hui, CC
Ngan, ESW
2021
11
CRISPR-Cas9 mediated correction of Hirschsprung-associated mutations in human iPSC restores neural crest cell functions
Proceeding/Conference:
EMBO Conference: Advances in Stem Cells and Regenerative Medicine
Lau, CST
Lai, PL
Ngan, ESW
2017
62
Establishment of experimental paradigm for generation of functioning enteric neurons from human pluripotent stem cells using single cell transcriptomics and human innervated colonic organoids
Proceeding/Conference:
International Society for Stem Cell Research (ISSCR) Annual Meeting, 2019
Lau, CST
Li, Z
Lai, PL
Lui, NC
Li, P
Munera, J
Mathe, M
Wells, J
Ngan, ESW
2019
31
Functional study of non-coding variants in Hirschsprung disease using human pluripotent stem cell-based model
Proceeding/Conference:
International Society for Stem Cell Research (ISSCR) Annual Meeting, 2019
Lui, NC
Fu, AX
Lai, PL
Lau, CST
Li, P
Yip, KYL
Ngan, ESW
2019
44
Generation of isogenic iPSC with RET mutation using CRISPR-Cas9
Proceeding/Conference:
CiRA-ISSCR International Symposium
Lai, PL
Lau, CST
Ngan, ESW
2016
48
Identification of Genes Associated with Hirschsprung Disease, Based on Whole-genome Sequence Analysis, and Potential Effects on Enteric Nervous System Development
Journal:
Gastroenterology
Tang, SM
Li, P
Lai, PL
Fu, A
Lau, CST
So, MT
Lui, NC
Li, Z
Zhuang, X
Yu, M
2018
120
Investigating the implications of RET variant/mutation in Hirschsprung disease pathogenesis using patient-specific iPSC
Proceeding/Conference:
CiRA-ISSCR International Symposium
Lau, CST
Lai, PL
Ngan, ESW
2016
92
iPSC-based disease model reveals defective APP processing by BACE2 as a novel disease mechanism underlying Hirschsprung
Proceeding/Conference:
The 5th International Symposium on Development of the Enteric Nervous System: cells, signals genes and therapy, 2018
Li, P
Tang, SM
Lau, CST
Lai, PL
Lui, NC
Tam, PKH
Garcia-Barcelo, MM
Ngan, ESW
2018
52
Loss of Kinesin family member 7 (Kif7) in enteric neural crest interrupts the gangliogenesis of enteric nervous system.
Proceeding/Conference:
Gordon Research Conference: Neural Crest & Cranial Placodes: Insights into Gene Networks, Disease Models and Evolutionary Mechanisms of Neural Crest and Cranial Placode Development
Zhou, T
Lai, PL
Hui, CC
Ngan, ESW
2017
54
Perturbed SUFU-GLI-SOX10 regulatory network underlies defective enteric nervous system development and Hirschsprung disease
Proceeding/Conference:
International Symposium on ENS Meeting
Ngan, E
Liu, AJ
Lai, PL
Gui, H
Sham, MH
Garcia-Barcelo, MM
Hui, CC
2015
51
Regulation of neuronal progenitors of the enteric nervous system by Kinesin family member 7 - GLI family Zinc finger 2 mediated Hedgehog pathway
Proceeding/Conference:
The 5th International Symposium on Development of the Enteric Nervous System: cells, signals genes and therapy, 2018
Zhou, T
Lai, PL
Lau, CST
Hui, CC
Ngan, ESW
2018
36
Single-cell RNA sequencing reveals differentiation trajectories directing human neural crest formation and differentiation
Proceeding/Conference:
International Society for Stem Cell Research (ISSCR) Annual Meeting 2018
Ngan, ESW
Li, Z
Lau, CST
Lai, PL
Tam, PKH
2018
59
