Browsing by Author Blobel, Carl P.

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Showing results 1 to 11 of 11
TitleAuthor(s)Issue DateViews
 
ADAM17 stabilizes its interacting partner inactive Rhomboid 2 (iRhom2) but not inactive Rhomboid 1 (iRhom1)
Journal:Journal of Biological Chemistry
Weskamp, GiselaTüshaus, JohannaLi, DanielFeederle, ReginaMaretzky, ThorstenSwendemann, StevenFalck-Pedersen, ErikMcIlwain, David R.Mak, Tak W.Salmon, Jane E.Lichtenthaler, Stefan F.Blobel, Carl P.
2020
15
 
Blood-induced bone loss in murine hemophilic arthropathy is prevented by blocking the iRhom2/ADAM17/TNF-α pathway
Journal:Blood
Haxaire, ColineHakobyan, NarinePannellini, TaniaCarballo, CamilaMcIlwain, DavidMak, Tak W.Rodeo, ScottAcharya, SuchitraLi, DanielSzymonifka, JackieSong, XiangqianMonette, SébastienSrivastava, AlokSalmon, Jane E.Blobel, Carl P.
2018
18
 
Deletions in the cytoplasmic domain of iRhom1 and iRhom2 promote shedding of the TNF receptor by the protease ADAM17
Journal:Science Signaling
Maney, Sathish K.McIlwain, David R.Polz, RobinPandyra, Aleksandra A.Sundaram, BalamuruganWolff, DoritOhishi, KazuhitoMaretzky, ThorstenBrooke, Matthew A.Evers, AstridVasudevan, Ananda A.JaguvaAghaeepour, NimaScheller, JürgenMünk, CarstenHäussinger, DieterMak, Tak W.Nolan, Garry P.Kelsell, David P.Blobel, Carl P.Lang, Karl S.Lang, Philipp A.
2015
12
 
iRhom2 controls the substrate selectivity of stimulated ADAM17-dependent ectodomain shedding
Journal:Proceedings of the National Academy of Sciences of the United States of America
Maretzky, ThorstenMcIlwain, David R.Issuree, Priya Darshinee A.Li, XueMalapeira, JordiAmin, SadafLang, Philipp A.Mak, Tak W.Blobel, Carl P.
2013
11
 
iRHOM2 is a critical pathogenic mediator of inflammatory arthritis
Journal:Journal of Clinical Investigation
Issuree, Priya Darshinee A.Maretzky, ThorstenMcIlwain, David R.Monette, SébastienQing, XiaopingLang, Philipp A.Swendeman, Steven L.Park-Min, Kyung HyunBinder, NikolausKalliolias, George D.Yarilina, AnnaHoriuchi, KeisukeIvashkiv, Lionel B.Mak, Tak W.Salmon, Jane E.Blobel, Carl P.
2013
11
 
iRhom2 promotes lupus nephritis through TNF-α and EGFR signaling
Journal:Journal of Clinical Investigation
Qing, XiaopingChinenov, YuriiRedecha, PatriciaMadaio, MichaelRoelofs, Joris J.T.H.Farber, GregoryIssuree, Priya D.Donlin, LauraMcllwain, David R.Mak, Tak W.Blobel, Carl P.Salmon, Jane E.
2018
58
 
iRhom2 regulates CSF1R cell surface expression and non-steady state myelopoiesis in mice
Journal:European Journal of Immunology
Qing, XiaopingD. Rogers, LindsayMortha, ArthurLavin, YonitRedecha, PatriciaIssuree, Priya D.Maretzky, ThorstenMerad, MiriamR. McIlwain, DavidMak, Tak W.Overall, Christopher M.Blobel, Carl P.Salmon, Jane E.
2016
9
 
iRhom2 regulation of TACE controls TNF-mediated protection against Listeria and responses to LPS
Journal:Science
McIlwain, David R.Lang, Philipp A.Maretzky, ThorstenHamada, KoichiOhishi, KazuhitoManey, Sathish KumarBerger, ThorstenMurthy, AdityaDuncan, GordonXu, Haifeng C.Lang, Karl S.Häussinger, DieterWakeham, AndrewItie-Youten, AnnickKhokha, RamaOhashi, Pamela S.Blobel, Carl P.Mak, Tak W.
2012
14
 
iRhoms 1 and 2 are essential upstream regulators of ADAM17-dependent EGFR signaling
Journal:Proceedings of the National Academy of Sciences of the United States of America
Li, XueMaretzky, ThorstenWeskamp, GiselaMonette, SébastienQing, XiaopingIssuree, Priya Darshinee A.Crawford, Howard C.McIlwain, David R.Mak, Tak W.Salmon, Jane E.Blobel, Carl P.
2015
11
 
Substrate-selective protein ectodomain shedding by ADAM17 and iRhom2 depends on their juxtamembrane and transmembrane domains
Journal:FASEB Journal
Tang, BeiyuLi, XueMaretzky, ThorstenPerez-Aguilar, Jose ManuelMcIlwain, DavidXie, YifangZheng, YufangMak, Tak W.Weinstein, HarelBlobel, Carl P.
2020
19
 
The xenoestrogens biphenol-A and nonylphenol differentially regulate metalloprotease-mediated shedding of EGFR ligands
Journal:Journal of Cellular Physiology
Urriola-Muñoz, PaulinaLi, XueMaretzky, ThorstenMcIlwain, David R.Mak, Tak W.Reyes, Juan G.Blobel, Carl P.Moreno, Ricardo D.
2018
10
Showing results 1 to 11 of 11