Browsing by Author Chan, Ho Yin Edwin

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Showing results 1 to 20 of 20
TitleAuthor(s)Issue DateViews
 
A Peptidylic Inhibitor for Neutralizing <inf>r</inf>(GGGGCC)<inf>exp</inf>-Associated Neurodegeneration in C9ALS-FTD
Journal:Molecular Therapy - Nucleic Acids
Zhang, QianAn, YingChen, Zhefan StephenKoon, Alex ChunLau, Kwok FaiNgo, Jacky Chi KiChan, Ho Yin Edwin
2019
10
 
A peptidylic inhibitor for neutralizing expanded CAG RNA-induced nucleolar stress in polyglutamine diseases
Journal:RNA
Zhang, QianChen, Zhefan StephenAn, YingLiu, HaizhenHou, YonghuiLi, WenLau, Kwok FaiKoon, Alex ChunNgo, Jacky Chi KiChan, Ho Yin Edwin
2018
8
 
Assessing a peptidylic inhibitor-based therapeutic approach that simultaneously suppresses polyglutamine RNA- And proteinmediated toxicities in patient cells and Drosophila
Journal:DMM Disease Models and Mechanisms
Zhang, QianTsoi, HoPeng, ShaohongLi, Pan P.Lau, Kwok FaiRudnicki, Dobrila D.Ngo, Jacky Chi KiChan, Ho Yin Edwin
2016
 
CAG expansion induces nucleolar stress in polyglutamine diseases
Journal:Proceedings of the National Academy of Sciences of the United States of America
Tsoi, HoLau, Terrence Chi KongTsang, Suk YingLau, Kwok FaiChan, Ho Yin Edwin
2012
 
Development of Fluorescent Probe for CAG-RNA Repeats
Journal:Biosensors
Lau, Ho Yan MatthewWong, Chun HoChan, Ho Yin EdwinAu Yeung, Ho Yu
25-Nov-2022
 
Drosophila exo70 is essential for neurite extension and survival under thermal stress
Journal:Journal of Neuroscience
Koon, Alex ChunChen, Zhefan StephenPeng, ShaohongFung, Joyce Man SeeZhang, XiaomanLembke, Kayly M.Chow, Hoi KinFrank, C. AndrewJiang, LiwenLau, Kwok FaiChan, Ho Yin Edwin
2018
11
 
Drosophila melanogaster as a model organism to study RNA toxicity of repeat expansion-associated neurodegenerative and neuromuscular diseases
Journal:Frontiers in Cellular Neuroscience
Koon, Alex C.Chan, Ho Yin Edwin
2017
 
Expanded polyalanine tracts function as nuclear export signals and promote protein mislocalization via eEF1A1 factor
Journal:Journal of Biological Chemistry
Li, LiNg, Nelson Ka LamKoon, Alex ChunChan, Ho Yin Edwin
2017
 
Expanded polyglutamine domain possesses nuclear export activity which modulates subcellular localization and toxicity of polyQ disease protein via exportin-1
Journal:Human Molecular Genetics
Chan, Wing ManTsoi, HoWu, Chi ChungWong, Chi HangCheng, Tat CheungLi, Hoi YeungLau, Kwok FaiShaw, Pang ChuiPerrimon, NorbertChan, Ho Yin Edwin
2011
 
Expression of expanded CAG transcripts triggers nucleolar stress in huntington's disease
Proceeding/Conference:Cerebellum
Tsoi, HoChan, Ho Yin Edwin
2013
 
FipoQ/FBXO33, a Cullin-1-based ubiquitin ligase complex component modulates ubiquitination and solubility of polyglutamine disease protein
Journal:Journal of Neurochemistry
Chen, Zhefan StephenWong, Azaria Kam YanCheng, Tat CheungKoon, Alex ChunChan, Ho Yin Edwin
2019
7
 
GULP1/CED-6 ameliorates amyloid-β toxicity in a Drosophila model of Alzheimer's disease
Journal:Oncotarget
Chiu, Wai Yin VivienKoon, Alex ChunNgo, Jacky Chi KiChan, Ho Yin EdwinLau, Kwok Fai
2017
4
 
MicroRNAs regulate the sesquiterpenoid hormonal pathway in Drosophila and other arthropods
Journal:Proceedings of the Royal Society B: Biological Sciences
Qu, ZheBendena, William G.Nong, WenyanSiggens, Kenneth W.Noriega, Fernando G.Kai, Zhen PengZang, Yang YangKoon, Alex C.Chan, Ho Yin EdwinChan, Ting FungChu, Ka HouLam, Hon MingAkam, MichaelTobe, Stephen S.Hui, Jerome Ho Lam
2017
 
Neuronal adaptor FE65 stimulates Rac1-mediated neurite outgrowth by recruiting and activating ELMO1
Journal:Journal of Biological Chemistry
Li, WenTam, Ka Ming VincentChan, Wai Wa RayKoon, Alex ChunNgo, Jacky Chi KiChan, Ho Yin EdwinLau, Kwok Fai
2018
 
Perturbation of U2AF65/NXF1-mediated RNA nuclear export enhances RNA toxicity in polyQ diseases
Journal:Human Molecular Genetics
Tsoi, HoLau, Chi KongLau, Kwok FaiChan, Ho Yin Edwin
2011
 
Planar cell polarity gene Fuz triggers apoptosis in neurodegenerative disease models
Journal:EMBO Reports
Chen, Zhefan StephenLi, LiPeng, ShaohongChen, Francis M.Zhang, QianAn, YingLin, XiaoLi, WenKoon, Alex ChunChan, Ting FungLau, Kwok FaiNgo, Jacky Chi KiWong, Wing TakKwan, Kin MingChan, Ho Yin Edwin
2018
7
 
Roles of the nucleolus in the CAG RNA-mediated toxicity
Journal:Biochimica et Biophysica Acta - Molecular Basis of Disease
Tsoi, HoChan, Ho Yin Edwin
2014
 
The aqueous extract of rhizome of gastrodia elata protected drosophila and PC12 cells against beta-amyloid-induced neurotoxicity
Journal:Evidence-based Complementary and Alternative Medicine
Ng, Chun FaiKo, Chun HayKoon, Chi ManXian, Jia WenLeung, Ping ChungFung, Kwok PuiChan, Ho Yin EdwinLau, Clara Bik San
2013
 
The ion channel activity of the SARS-coronavirus 3a protein is linked to its pro-apoptotic function
Journal:International Journal of Biochemistry and Cell Biology
Chan, Chak MingTsoi, HoChan, Wing ManZhai, ShenyuWong, Ching OnYao, XiaoqiangChan, Wood YeeTsui, Stephen Kwok WingChan, Ho Yin Edwin
2009
 
The SARS-coronavirus membrane protein induces apoptosis via interfering with PDK1PKB/Akt signalling
Journal:Biochemical Journal
Tsoi, HoLi, LiChen, Zhefan S.Lau, Kwok FaiTsui, Stephen K.W.Chan, Ho Yin Edwin
2014
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