Dataset

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Title of Dataset
GSE10854: The anti-angiogenic and anti-tumor cell signaling networks of the kringle 1 domain of hepatocyte growth factor (HGFK1)
Author of Dataset
Leung, Wing-Sze1
Shen, Zan1
Kung, Hsiang F1
Lin, Marie C1
Contact
Leung, Wing-Sze1
Date of Dataset Creation
2008-03-17
Description
Previously, we have demonstrated that the recombinant adeno-associated virus carrying the kringle domain 1 of hepatocyte growth factor (rAAV-HGFK1) gene is a potential anti-angiogenic approach for the treatment of hepatocellular carcinoma (HCC) and exerts direct inhibition effects on tumor cells. Here, using genome-wide expression profiling technology, coupled with RT-PCR validation, we investigated the differentially expressed genes and proposed the mechanisms involved in HGFK1 anti-angiogenic and anti-tumor cell signaling networks.
Citation
Leung, WS, Shen, Z, Kung, HF, Lin, MC. (2008). GSE10854: The anti-angiogenic and anti-tumor cell signaling networks of the kringle 1 domain of hepatocyte growth factor (HGFK1). [Data File]. https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE10854
Subject (RGC Codes)
P1 — Chemical Engineering — 化學工程
  • 3105 — Biochemical Engineering — 生物化學工程
Subject (ANZSRC)
03 — CHEMICAL SCIENCES — 化學科學
  • 0304 — MEDICINAL AND BIOMOLECULAR CHEMISTRY — 醫藥和生物分子化學
    • 030499 — Medicinal and Biomolecular Chemistry not elsewhere classified
Keyword
Mus musculus
Rattus norvegicus
Affiliations
  1. The University of Hong Kong, Computer Science, Open Laboratory of Chemical Biology, 8S03, Kadoorie Biological Sciences Building, The University of Hong Kong, Hong Kong, China