Community View Count

Geo Map
Region#
AS - Asia200762
NA - North America62269
EU - Europe51020
HKU - The University of Hong Kong20599
AF - Africa2723
OC - Oceania596
SA - South America404
UND - Undefined1483
Total339856
Country#
CN - China160574
US - United States60553
HKU - The University of Hong Kong20599
GB - United Kingdom19516
HK - Hong Kong14825
FR - France13657
KR - Republic of Korea13192
SG - Singapore6982
DE - Germany5870
RU - Russia3723
OTH - Others20365
Total339856
City#
Beijing28998
Ashburn28197
Nanjing24134
The University of Hong Kong20599
Shenzhen16549
Tianjin9105
Central District8507
Singapore6951
Zhengzhou4941
Clarks Summit4542
Others187333
Total339856
Genetic polymorphisms and periodontitis in Hong Kong Chinese68
Model Systems for Intervertebral Disc regeneration45
Molecular and developmental insights into the pathogenesis of the Sox9Y44X campomelic dysplasia mutation54
Matrix remodeling during intervertebral disc growth and degeneration detected by multichromatic FAST staining (Journal of Histochemistry and Cytochemistry (2009) 57, (3), (249-256))87
Renal proteoglycans: roles in the initiation of renal stone66
Signals involved in the switch to fate commitment of bone marrow-derived Schwann cells38
Inorganic polyphosphate triggers interleukin 11 production in osteoblasts cell signalling1258
Altered NPY and AgRP in membrane type-1 matrix metalloproteinase-deficient mice116
Interplay between ER stress and hypoxia pathways in chondrocytes68
From the marrow to two glial lineages: derivation of oligodendrocyte precursors and Schwann cells from bone marrow stromal cells for remyelination therapy40
Characterization of Heparanase 1 and Heparanase 2 at Hippocampus63
Chondroitinase ABC promotes axonal regrowth of Clarke's neurons into peripheral nerve graft after hemisection of the spinal cord59
Deletion of laminin-8 results in increased tumor neovascularization and metastasis in mice111
Lineage extension chondrocytes and the ontogeny of bone cells126
Urinary glycosaminoglycans differ in their calcium oxalate crystallization activities65
Transgenic CHD1L expression in mouse induces spontaneous tumors84
Peer generated MCQs to assess and support for learning in a Problem Based Learning Programme155
Advances in DNA diagnostic technology46
Genome-wide haplotype association mapping (HAM) in mice leads to an identification of a genetic variant in CER1 associated with bone mineral density and fracture in southern Chinese women81
Defective ATM-Kap-1-mediated chromatin remodeling impairs DNA repair and accelerates senescence in progeria mouse model93
The roles of Irx3 and Irx5 genes in inner ear sensorineural patterning52
Functional study of cerberus-like protein: towards a biochemical understanding of BMP antagonists in skeletal disorders74
Semaphorin 3A associated with chondroitin sulfates on perineuronal nets regulates developmental maturation of the central vestibular circuitry52
Lack of β1 integrin in the developing mouse notochord results in hemivertebrae62
Tensin2 variant 3 is associated with aggressive tumor behavior in human hepatocellular carcinoma72
Comprehensive Analysis of MRI‐phenotypes Provides New Insights into Lumbar Disc Degeneration for Genetic Studies92
Characterization of an arginine 789 to cysteine substitution in α1 (II) collagen chains of a patient with spondyloepiphyseal dysplasia71
Suppressor of fused controls the maintenance of neural progenitor pools and regulates notch pathway activity in rhombomere 440
Association between FCGR3A polymorphisms and periodontitis in Hong Kong Chinese72
Growth inhibitory & facilitatory aspects of chondroitin sulfates in vivo and in vitro55
Identification and Characterization of Human VCY2-Interacting Protein: VCY2IP-1, a Microtubule-Associated Protein-Like Protein98
The roles of Irx3 and Irx5 in mammalian inner ear development114
Nar1 deficiency results in shortned lifespan and sensitivity to paraquat that is rescued by increased expression of mitochondrial superoxide dismutase64
Comparative immunological evaluation of recombinant Salmonella Typhimurium strains expressing model antigens as live oral vaccines95
Arabidopsis membrane-associated acyl-CoA-binding protein ACBP1 is involved in stem cuticle formation130
Epithelial morphogenesis in three-dimensional cell culture system236
The activity of liver-enriched and growth-suppressive transcription factor CREB-H is tightly regulated by N-linked glycosylation and ubiquitination75
Predictive models for protein crystallization121
Yeast arginine methyltransferase Hmt1p regulates transcription elongation and termination by methylating Npl3p86
Prediction of osteoporosis candidate genes by computational disease gene identification strategy61
Erratum: NMR studies of 4-methylimidazole binding to cytochrome c: Effects of methyl substituent on the binding affinity, the orientation of the ligand plane, and the electronic structure of the heme (Journal of the Chemistry Society, Dalton Transactions (2000) (4069))61
Visualizing the proteome of escherichia coli by recombineering technology66
REV7-mediated polyubiquitination and degradation of human DNA translesion synthesis polymerase REV161
Investigating the role of Sox9 in human neural stem cells56
The effects of chondroitinase ABC digestion products on neurite growth: saccharide length and sulphation pattern42
N-Acetylcysteine and allopurinol up-regulated the Jak/STAT3 and PI3K/Akt pathways via adiponectin and attenuated myocardial postischemic injury in diabetes152
Maturation profile of thalamic neurons responsive to rotational and translational motions63
Cold-inducible RNA binding protein is required for the expression of adhesion molecules and embryonic cell movement in Xenopus laevis141
The paradoxical relationship between ligamentum flavum hypertrophy and developmental lumbar spinal stenosis68
Structure of RPA32 bound to N-terminus of SMARCAL1 redefines the binding interface between RPA32 and its interacting proteins49
The Hong Kong Genome Wide Association Study: How should we move forward?32
Sox10 mutation affects enteric neural crest cell migration66
Overexpression of epidermal growth factor induced hypospermatogenesis in transgenic mice103
Etiology of developmental spinal stenosis: A genome‐wide association study80
Specific TATAA and bZIP requirements suggest that HTLV-I Tax has transcriptional activity subsequent to the assembly of an initiation complex79
Dysregulation of mitotic spindle checkpoint control in hepatocellular carcinomas69
Yeast two-hybrid screening for new binding partners of CIKS61
Genetic association studies in lumbar disc degeneration: a systematic review62
Epstein-Barr virus latent membrane protein 1 (LMP1) upregulates Id1 expression in nasopharyngeal epithelial cells125
Sox2 regulates hair type specification and pigmentation49
Anti-HBV drug and treatment80
A locus for congenital preauricular fistula maps to chromosome 8q11.1-q13.31265
Structural studies of intermediates along the reaction pathway of ADP-ribosyl cyclase55
Association of the Asporin D14 allele to lumbar disc degeneration in Chinese and Japanese88
A comprehensive framework for prioritizing variants in exome sequencing studies of Mendelian diseases109
Understanding the function of the Mll-een leukaemic fusion gene by embryonic stem cell approaches195
Asymptomatic members with SOD1 mutation in a large kindred with familial amyotrophic lateral sclerosis have abnormal water diffusion characterisitcs122
Chromosomal tagging of the C terminals of E. Coli gene products51
Comparison of the effect of non-selective NSAID and Cycloosygenoase-2 (COX-2) selective NSAID on bone formation - implications for spinal fusion58
Studying enteric nervous system development using the Sox10[delta]5 mouse mutant174
H5-type influenza hemagglutinin is functionally recognized by the natural killer activating receptor, Nkp4499
Functions of suppressor of fused (Su(fu)) in mammalian midbrain and hindbrain neurogenesis52
S-maltoheptaose targets syndecan-bound effectors to reduce smoking-related neutrophilic inflammation.159
Functional characterization of SOX10 mutations for understanding the molecular pathogenesis of Waardenburg-Hirschsprung syndrome61
Role of a novel splice variant of mitotic arrest deficient 1 (MAD1), MAD1β, in mitotic checkpoint control in liver cancer108
Loss of yeast peroxiredoxin Tsa1p induces genome instability through activation of the DNA damage checkpoint and elevation of dNTP cellular levels64
Investigating the protective role of FOXM1 against oxidative stress and DNA damage in human embryonic stem cells126
Collagen studies in newborn rat kidneys with incomplete ureteric obstruction108
Sox10 NGFP mutation affects migration of enteric neural cress cells in mouse embryonic gut70
Nutritional zinc-deficiency and nitrosamine-induced carcinogenesis in the rat207
Collagen-mesenchymal stem cell microspheres for cartilage tissue engineering74
Activity-dependent GABAergic synaptic plasticity in medial vestibular neurons of rats99
Cre-transgenic mouse line for conditional gene knockout in retinal rod bipolar cells95
Fate commitment of human bone marrow stromal cells to Schwann cells54
Bioinformatic and functional approaches to identify potential SOX9 target genes in inner ear development168
The role of unfolded protein response in the cytotoxicity mechanism ofN-(4-hydroxyphenyl)retinamide359
Neuronal proheparanase regulates synaptic function of the central vestibular system92
Understanding the molecular mechanisms of skeletal dysplasia through proteomics of mutant collagen X protein-expressing chondrocytes72
Characterization of a novel X-linked nuclear protein down-regulated in neonatal mouse hypoxic-ischemic encephalopathy, HID-163
Spike protein, S, of human coronavirus HKU1: Role in viral life cycle and application in antibody detection96
Premature aging and genomic instability in mice lacking zmpste2465
Suppressor of fused (Su(fu)) modulates hindbrain hedgehog signaling and neurogenesis56
Bridge acts as a coactivator of E2A-Mediated regulation of the insulin gene38
sPDZD2, a novel modulator in Hedgehog signaling87
Co-evolution of transcription factors and their binding sites64
Secretin is widely expressed during mouse embryonic development98
The induction of p21/WAF1/CIP1 expression by the specific kappa opioid receptor agonist is independent of MAPK and PKC50
The double-stranded RNA-binding protein PACT activates cytoplasmic viral sensor MDA5 by promoting its oligomerization67
Small molecule approach to direct differentiation of human induced pluripotent stem cells to sensory neurons52
Identification of a DNA aptamer that inhibits sclerostin's antagonistic effect on Wnt signalling118
Multiple alkane hydroxylase systems in a marine alkane degrader, Alcanivorax dieselolei B-5102
Effects of Ext1 and Ext2 mutations in a chondrocyte cell line on heparan sulfate synthesis and in vitro chondrogenesis170
Endocannabinoid regulates developmental plasticity of GABAergic synapses in the rat medial vestibular nucleus73
A cell model system to study the effect of ext mutations on in vitro chondrogenesis72
Uncovering small chemical molecules for treatment of intervertebral disc degeneration93
Sox10 is essential for neural crest invasion in cochlea-vestibular ganglion68
Are There Protective Genes for Disc Degeneration?82
Reconstitution of nucleus pulposus cell matrix niche in 3D collagen microsphere for mesenchymal stem cell discogenic differentiation61
Nitrogen plasma-implanted nickel titanium alloys for orthopedic use107
Growth inhibition and morphological alterations induced by hexamethylene bisacetamide on a human colon cancer cell line75
REV7-mediated polyubiquitination and degradation of human REV151
The enzyme activity of a membrane-bound isoform of thioredoxin reductase is inhibited by adenine mononucleotide53
STAT3 as a downstream mediator of Trk signaling and functions107
Genetic and epigenetic alterations on DLC-1 gene in hepatocellular carcinoma79
Systematic analysis of the role of transcription regulators in distal interactions39
Recombinant ESAT-6-Like Proteins Provoke Protective Immune Responses against Invasive Staphylococcus aureus Disease in a Murine Model69
Explicit hypoxia targeting with tumor suppression by creating an "obligate" anaerobic Salmonella Typhimurium strain112
Decellularization of chondrocyte-encapsulated collagen microspheres: a 3D model to study effects of acellular matrix on stem cell fate85
Human paraoxonase gene cluster transgenic overexpression represses atherogenesis and promotes atherosclerotic plaque stability in ApoE-Null Mice103
Novel plasma-implanted 'smart' metallic materials for orthopedic implants61
The roles of Irx3/5 genes and hedgehog signaling in mammalian cochlear development103
Immunogold localization of alkaline phosphatase in a human osteosarcoma cell line (SAOS-2)53
Human Yip1A specifies the localization of Yif1 to the Golgi apparatus148
Spdzd2 is a putative regulatory factor of insulin gene expression and pancreatic b-cell growth72
The p21/WAF1/Cip1 mediates the anti-mitogenic but not the anti-apoptotic action of epidermal growth factor (EGF) in an epithelial tumor cell line84
Correlation between developmental chondroitin sulfate pattern and the upregulation of chondroitin 6-sulfotransferase mRNA expression in the embryonic hindbrain66
Calcium oxalate crystallizing properties of macromolecules released by renal tubular cells in vitro80
Effect of high-fat meals and fatty acid saturation on postprandial levels of the hormones ghrelin and leptin in healthy men101
ProteoMirExpress: inferring microRNA-centered regulatory networks from high-throughput proteomic and transcriptome data93
Plasma amyloid-β oligomers level is a biomarker for Alzheimer's disease diagnosis149
Extracellular matrix in planarian regeneration and stem cell maintenance74
Alleviating ER stress in chondrocytes: survival strategies with double-edged developmental consequences104
Understanding the molecular pathogenesis of SOX9 Y440X campomelic dysplasia71
Control of cell fate and lineages in skeletal development37
Insights into the function of Sox9 and the molecular pathogenesis of campomelic dysplasia53
Hox genes: A molecular code for patterning regional diversity in the nervous system and branchial structures89
The leukaemia fusion gene, Mll-Een affects haemopoietic development in mouse embryonic stem cells with enhanced proliferation and self renewal of myeloid progenitors59
Exhaustion of nucleus pulposus progenitor cells with ageing and degeneration of the intervertebral disc88
Functional significance of the 3'-UTR in the mRNA of the stress-inducible protein CHOP/Gadd15341
Towards functional recovery in the injured CNS: Generating oligodendrocyte precursors from bone marrow stromal cells for remyelination61
The roles of Sox9 and its regulatory elements in campomelic dysplasia63
Impact of intracellular clearance of unfolded proteins on chondrocytes cell fate57
Preparations of Chitosan Support for Cultures of Schwann Cells and Transdifferentiated Mesenchymal Stem Cells64
Regeneration of functional sweat gland-like structures by transplanted differentiated bone marrow mesenchymal stem cells92
The role/s of type IIA procollagen in BMP (Bone morphogenetic protein) Signalling51
Tax-induced recruitment of TORC family coactivators is required for transcriptional activation of HTLV-I LTR67
Expression of TrkA, TrkB and TrkC receptors in the central pathway of trigeminal proprioception in the rat79
Identification of a Smad4/YY1-recognized and BMP2-responsive transcriptional regulatory module in the promoter of mouse GABA transporter subtype I (Gat1) gene114
Polyubiquitination of REV1 is regulated by REV756
Neochondrogenesis for articular bone-cartilage defect: the use of free periosteal graft, porous metal mould and continuous passive motion in a rabbit model101
A genetic approach for disease gene discovery in the mouse79
Development of a micromanipulator-based loading device for mechanoregulation study of human mesenchymal stem cells in three-dimensional collagen constructs117
Low frequency of TAU mutations and further genetic heterogeneity in FTD60
Oxygen and sodium plasma-implanted nickel-titanium shape memory alloy: a novel method to promote hydroxyapatite formation and suppress nickel leaching94
Studying the roles of mouse Sox10 in Schwann cell development and Wallerian degeneration.60
Reduced neuronal nitric oxide production from KIF5B-deficiency mice50
Multiexon deletions in the type I collagen COL1A2 gene in osteogenesis imperfecta type IB. Molecules containing the shortened α2(I) chains show differential incorporation into the bone and skin extracellular matrix69
In vivo selection and characterization of DNA aptamers against H5N1 virus nucleoprotein133
Upregulation of ICAM-1 expression in bronchial epithelial cells by airway secretions in bronchiectasis103
In vitro expression analysis of collagen biosynthesis and assembly90
Insulin-like growth factors 1 and 2 induce lymphangiogenesis in vivo92
Small noncoding RNA GcvB is a novel regulator of acid resistance in Escherichia coli119
Assessment of next generation sequencing analysis tools shows lower coverage and poorer SNP-calling quality in the CpG islands and regulatory regions in cancer genome63
Loss of MT1-MMP facilitates iPSCs self-renewal110
Identification of multiple isoforms of DLC2, a novel tumor suppressor gene, and their functional characterization in hepatocellular carcinoma78
Mannose binding lectin and autoimmune disease72
A regulatory polymorphism in interferon-γ receptor 1 promoter is associated with the susceptibility to chronic hepatitis B virus infection98
Cdk5-mediated phosphorylation of endophilin B1 is required for induced autophagy in models of Parkinson's disease146
MT1-MMP Inactivates ADAM9 to Regulate FGFR2 Signaling and Calvarial Osteogenesis123
Neural Stem Cells Harvested from Live Brains by Antibody-Conjugated Magnetic Nanoparticles100
Axon-restrictive chondroitin sulfates at the Schwann cell-astroycte interface204
Aptamers against polyphosphate kinase 2 (PPK2) from mycobacterium tuberculosis as a potential approach of novel anti-tuberculosis therapy78
The investigation of fibrinolytic activity in human intestinal tissue: identification, characterisation andpartial purification of two plasminogen activators194
Perlecan compartmentalizes collagen X in the mammalian growth plate82
Defects in cochlear structure and function in the Sox9Y440X campomelic dysplasia mouse model65
Acyl-CoA binding proteins from sunflower seeds76
Regulation of procollagen synthesis and processing during ascorbate-induced extracellular matrix accumulation in vitro72
Tissue-specific transcriptional regulation of Sox2 expression in mouse inner ear development48
Phosphorylation of matrix vesicle components-dependence on alkaline phosphatase48
Platelet activity and arachidonic acid metabolism: modulation by factors in plasma and cerebrospinal fluidand by diet174
Intron-exon structure, alternative use of promoter and expression of the mouse collagen X gene, Col10a-182
Molecular cloning and functional analysis of chondroitin 6-sulfotransferase (rat) in relation to post-traumatic nerveregeneration226
IHH and FGF8 coregulate elongation of digit primordia1285
Ex Vivo Generation of Myelinating Schwann-cell Like Cells from Bone Marrow-derived Neurospheres79
Modifications in perineuronal nets of rat vestibular nuclear neurons after unilateral labyrinthectomy52
Upregulation of GADD153 expression in the apoptotic signaling of N-(4-hydroxyphenyl)retinamide (4HPR)67
csi2p modulates microtubule dynamics and organizes the bipolar spindle for chromosome segregation40
The role of MAPK and Nrf2 pathways in ketanserin-elicited attenuation of cigarette smoke-induced induced iL-8 production in human bronchial epithelial cells90
Regulation of gene transcription by NF-kB and stats downstream of the ret receptor tyrosinekinase in hirschsprung disease and thyroid cancer63
Evidence for an Alzheimer disease susceptibility locus on chromosome 12 and for further locus heterogeneity103
Transcriptional control of sensory progenitor specification in the inner ear31
A Hoxb3Mouse Mutant with Abnormal Thoracic Body Wall Development85
Analysis of SOX10 mutations identified in Waardenburg-Hirschsprung patients: Differential effects on target gene regulation111
The role of HPN and its related histidine-rich proteins in helicobacter pylori71
Recombinant adeno-associated virus expressing the receptor-binding domain of severe acute respiratory syndrome coronavirus S protein elicits neutralizing antibodies: Implication for developing SARS vaccines98
Dysregulation of mitotic spindle checkpoint control in hepatocellular carcinomas74
EYA1-SIX1 complex in neurosensory cell fate induction in the mammalian inner ear65
Genetic analyses of terminal differentiation of hypertrophic chondrocytes66
How has genetics research altered our understanding of degenerative disc disease: Implications for intervertebral disc regeneration102
Isolation of genomic DNA from claw clippings for genetic analysis in chickens78
Identification of biological inhibitors of the mammalian thioredoxin system183
Using small molecules to induce the progressive differentiation of hESCs into pancreatic β-cell-like progenitors62
Isolation of full-length cDNA and chromosomal localization of human NF- κB modulator NEMO to Xq2888
CRTC coactivators are required for hepatitis B virus transcription89
Delayed antiviral plus immunomodulator treatment still reduces mortality in mice infected by high inoculum of influenza A/H5N1 virus135
Characterization of an enhancer element for establishing transgenic mouse models for enteric nervous system development80
Formation of novel biological patterns by controlling cell motility307
IGG: A tool to integrate GeneChips for genetic studies96
Derivation of oligodendrocyte precursors from bone marrow stromal cells: new perspective in CNS myelin repair59
Epigenetic inactivation of CHFR in nasopharyngeal carcinoma through promoter methylation109
Characterize the specificity of CRE expression in cerebellar purkinje cells53
Assessment of Mapping and SNP-Detection Algorithms for Next-Generation Sequencing Data in Cancer Genomics146
Abnormal enteric ganglia development in a SOX 10 mouse mutant generated by gene targeting120
Use of a riboswitch-controlled conditional hypomorphic mutation to uncover a role for the essential csrA gene in bacterial autoaggregation140
Aldose reductase-deficient mice develop nephrogenic diabetes insipidus121
Hexamethylene bisacetamide changes proteoglycan metabolism in a human colon cancer cell line53
Analysis of the Static Protein Profile of Degenerated IVD Indicate Increased Fibrosis-Related Proteins131
Collagen X function and regulation of gene expression53
Sonic hedgehog regulates the proliferation, differentiation, and migration of enteric neural crest cells in gut97
RAS signalling in Mll-mediated Leukaemia57
Erratum: PKCδ-dependent deubiquitination and stabilization of Gadd45 in A431 cells overexposed to EGF (Biochemical and Biophysical Research Communication (2001) 285:2 (283-288))71
Heparanase modulates synaptic plasticity at the hippocampus68
Regeneration of nucleus pulposus cells for Degenerative Disc Disorder52
Light coat and circling (LCC) and yellow submarine (YSB) mutants are Sox2 conditional null models during hair morphogenesis103
The interplay between EPS8 and FOXM1 in carcinogenesis50
Addressing the pericellular matrix of reactive astrocytes76
Human T cell leukemia virus type 1 oncoprotein Tax targets the human mitotic checkpoint protein MAD1111
Intervening intervertebral disc degeneration by small molecules that positively modulate proteoglycan production59
DNA aptamer-mediated recognition of malaria diagnostic target Plasmodium lactate dehydrogenase – structure, discrimination and application25
Regulation of the mouse Hox-B3 gene expression57
Development of a virosome vaccine against aspergillus fumigatus71
The role of SOX10 during enteric nervous system development77
A novel ENU-induced mutation in Myo6 causes vestibular dysfunction and deafness108
Epidermal-growth factor is not a mitogen for the nasopharyngeal carcinoma-derived cell line, CNE-257
Protein expression of the intervertebral disc: in Health and disease52
The PERK/eIF2α signaling pathway of Unfolded Protein Response is essential for N-(4-hydroxyphenyl)retinamide (4HPR)-induced cytotoxicity in cancer cells106
Segmental regulation of Hoxb-3 by kreisler71
Myosin II is present in gastric parietal cells and required for lamellipodial dynamics associated with cell activation152
Vasostatin gene therapy suppressed lung tumor growth and metastasis using adeno-associated virus pseudotype 5 vector70
Abnormal chondrocyte differentiation in transgenic mice expressing a schmid metaphyseal chondrodysplasia col10a1 mutation70
Analysis of multiple cardiac abnormalities in a Boxb3 mouse mutant190
Genome-wide haplotype association mapping in mice identifies a genetic variant in CER1 associated with BMD and fracture in southern Chinese women193
The association of a single nucleotide polymorphism in the promoter region of the LAMA1 gene with susceptibility to chinese high myopia86
Comparative analysis of bZIP transcription factors of the CREB3 subfamily65
Fabrication and evaluation of chitosan devices for peripheral nerve regeneration: An initial study72
Regulation of development stage- and tissue- specific expression of the human COL2A1 and mouse COL10A1 genes in transgenic mice81
Genetic Variations of the Cholesterol Metabolism Pathway Genes and the risk of Alzheimer's Disease46
Injury-associated increase in 6-sulphated chondroitin sulphates in post-crush sciatic nerves of adult guinea pigs45
Regulatory analysis of the mouse Hoxb3 gene: Multiple elements work in concert to direct temporal and spatial patterns of expression90
Investigating the role of Sox9 in human neural stem cells66
Planar cell polarity in vertebrate limb morphogenesis66
Influence of Social Environment on Loneliness in Older Adults: Moderation by Polymorphism in the CRHR163
REV7-mediated polyubiquitination and degration of human REV1209
Bioinformatics studies of gene regulation of SOX9 and the SOX family53
The regulatory role of perineuronal nets in postnatal maturation of vestibular behavior system39
Phosphotransferase activity of bone alkaline phosphatase under physiological pH42
Structural and functional relationship of adiponectin as an anti-aging hormone54
Modulation of the unfolded protein response by the severe acute respiratory syndrome coronavirus spike protein80
Coupling of small leucine-rich proteoglycans to hypoxic survival of a progenitor cell-like subpopulation in Rhesus Macaque intervertebral disc118
SpliceNet: recovering splicing isoform-specific differential gene networks from RNA-Seq data of normal and diseased samples119
Lung cancer tumorigenicity and drug resistance are maintained through ALDH(hi)CD44(hi) tumor initiating cells122
Loss of procollagen IIA from the anterior mesendoderm disrupts the development of mouse embryonic forebrain105
Neuronal response sensitivity to bidirectional off-vertical axis rotations: A dimension of imbalance in the bilateral vestibular nuclei of cats after unilateral labyrinthectomy104
The use of a mouse model to understand the role of SOX9 in campomelic dysplasia and the notochord55
Sox10 mutation affects gliogenesis of the cochleo-vestibular ganglion81
Development and characterization of genetic mapping resources for the turkey (Meleagris gallopavo)80
Increased basal insulin secretion in Pdzd2-deficient mice117
Mouse ribosomal RNA genes contain multiple differentially regulated variants67
CYP46A1 functional promoter haplotypes decipher genetic susceptibility to Alzheimer's disease108
The study of KIF5B-mediated intracellular transport in neurons229
PDZD2, a candidate gene for brachydactyly type A1, encodes a secreted protein that negatively modulates hedgehog signaling57
MAD2 expression induces chemosensitization to DNA damaging agent, cisplatin, in nasopharyngeal carcinoma cells81
Regulation of pyruvate kinase isozymes in animal tissues230
WTO TRIPS and its effect on the supply and development of medicines in China63
Evaluation of nuclear factor-κB, urokinase-type plasminogen activator, and HBx and their clinicopathological significance in hepatocellular carcinoma81
The human α2(XI) collagen (COL11A2) chain. Molecular cloning of cDNA and genomic DNA reveals characteristics of a fibrillar collagen with differences in genomic organization89
'Obligate' anaerobic Salmonella strain YB1 suppresses liver tumor growth and metastasis in nude mice102
Analysis of glycosaminoglycans induced in newly formed calcium oxalate crystals using an undiluted urine system102
Widespread occurrence of ganglioside-stimulated protein kinase in animal brains70
Effects of reconstituted collagen matrix on fates of mouse embryonic stem cells before and after induction for chondrogenic differentiation87
IFI16β and STINGβ: negative regulators of innate immunity generated by alternative splicing69
Chondroitin sulfotransferase expression pattern in migrating motor neurons of the rat embryonic hindbrain1353
In vivo activation and nuclear translocation of phosphorylated glycogen synthase kinase-3β in neuronal apoptosis: Links to tau phosphorylation97
Circling, deafness and yellow coat displayed by chromosome 3 mouse mutants yellow submarien (Ysb) and light coat and circling (Lcc)68
The activity of N-(4-hydroxyphenyl) retinamide in nasopharyngeal carcinoma cells69
Imaging individual spindle microtubule dynamics in fission yeast82
Impaired angiogenesis, delayed wound healing and retarded tumor growth in Perlecan heparan sulfate-deficient mice123
Inducing the progressive differentiation of hESCs into pancreatic progenitor cells225
Genetic analyses of the roles of Sox2 and Sox18 in mouse hair development and growth363
Integrative analysis of high throughput data for regulatory network construction18
Strengthening biomedical science education among non-medical students through a common core course74
CIC, a member of a novel subfamily of the HMG-box superfamily, is transiently expressed in developing granule neurons125
COL10A1 nonsense and frame-shift mutations have a gain-of-function effect on the growth plate in human and mouse metaphyseal chondrodysplasia type Schmid192
Identification and characterization of long-range SOX9 enhancers in limb development55
Impact Of Activating Adamts-5 In Cartilage-related Degenerative Disorders58
Analysis of conjugated linoleic acid esters by nuclear magnetic resonance spectroscopy35
Improved amino acid flexibility parameters86
In vivo analysis of the transactivation specificity of group E SOX proteins114
Construction of nerve guidance channel with use of Schwann cell seeded aligned chitosan nanofibers56
Ubiquitous Aberrant RASSF1A Promoter Methylation in Childhood Neoplasia71
Erratum: Upregulation of chondroitin 6-sulphotransferase-1 facilitates Schwann cell migration during axonal growth (Journal of Cell Science (2006) vol. 119 (933-942))66
Quantitative electrophoretic study of the modification of sperm plasma membrane by the ampullary gland in the golden hamster87
Attentuation of cerebellar plasticity after neonatal perturbation of NMDA receptors in the vestibular nucleus66
Regulation of spatially-specific expression of the mouse homeobox gene Hox b-357
Fabrication and characterization of multi-channel chitosan nerve conduit and its potential application90
Highly restricted expression of Cre recombinase in cerebellar Purkinje cells173
Generation of induced pluripotent stem (iPS) cells from bone-forming cells89
Instructive role of DRG neurons in derivation of schwann cells from bone marrow stromal cells60
Nerve conduit constructed by aligned chitosan nanofibers for directing axonal growth in nerve regeneration313
The Potential Use of Heparinase-generated Heparin Fragments in the Treatment of Bronchiectasis and Chronic Obstructive Pulmonary Disease54
The use of small molecules to direct the differentiation of embryonic stem cells into insulin-secreting β-like cells91
DNA aptamers selected for the inhibition of E3 ubiquitin ligase WWP136
The decapentaplegic core promoter region plays an integral role in the spatial control of transcription95
Chromatin Remodeling, DNA Damage Repair and Aging68
Bismuth complexes inhibit the SARS coronavirus165
Ectopic expression of Hoxb3 in the second branchial arch leads to abnormal craniofacial development101
The developmental origin of osteoblasts in endochondral bone139
Sedlin and prostaglandin E2 dehydrogenase - interactions and implications for spondyloepiphyseal dysplasia tarda88
Bone and Development (Book Review)67
Investigation of the protein/polyphosphate binding interface: mutational studies on mycobacterium tuberculosis polyphosphate kinase 2 (PPK2)48
Over-representation pattern of SNPs in the genome of restless legs syndrome samples57
Disulphide production by Ero1α-PDI relay is rapid and effectively regulated54
Over-expression of FoxM1 facilitates progression through G2/M phase and stimulates expression of cyclin B159
Analysis of abnormal phenotypes of Hoxb3 mouse mutants generated by gene targeting175
Mitochondrial targeting of growth suppressor protein DLC2 through the START domain117
Quantitative characterization of mouse embryonic stem cell state transition210
A histological grading system for evaluating disc degeneration in the mouse55
An immunolocalization study of tissue inhibitors of metalloproteinase-1 of bone graft healing on parietal bone97
Exome sequencing reveals a heterozygous DLX5 mutation in a Chinese family with autosomal-dominant split-hand/foot malformation66
Single-stranded oligonucleotide-mediated gene repair in mammalian cells has a mechanism distinct from homologous recombination repair134
ASCL1 is essential in maintaining CD133+ cancer stem cells in HCC79
Collagen defects in lethal perinatal osteogenesis imperfecta101
Epigenetic silencing of miR-203 is a disease initiation event of multiple myeloma72
Aptamer-based piezoelectric quartz crystal biosensor for the SARS coronavirus helicase63
DNA-encoded dynamic libraries25
Isolation and detection of type IX collagen from adult human intervertebral disc63
A knowledge-based weighting framework to boost the power of genome-wide association studies99
Targeted disruption of the mouse type X collagen gene59
Late-life body mass index and waist circumference in amnestic mild cognitive impairment and alzheimer's disease127
Roles of yeast peroxiredoxins in cellular defence against DNA damage66
Reactive oxygen species (ROS) regulates the expression of the growth-arrest and DNA damage inducible gene-153 at the post-transcriptional level48
Down regulation of a novel proliferation responded gene in human breast cancer54
A Systematic and Simple Scoring System for Histological Analysis of the Mouse Intervertebral Disc during Natural Ageing, Degeneration, and Regeneration117
A study of intracellular signals of K-opioids in non-neuronal cells199
Structure of the adaptor protein p14 reveals a profilin-like fold with distinct function71
The growth plate abnormality in transgenic mice expressing type X collagen with a mutation in the NCI domain in dosage dependent54
MT1-MMP-Mediated cleavage of decorin in corneal angiogenesis106
Leucine-rich repeat kinase-2 (LRRK2) R1441G knockin mice are more susceptible to rotenone toxicity111
Baicalein inhibits formation of α-synuclein oligomers within living cells and prevents Aβ peptide fibrillation and oligomerisation127
Structural studies on urinary glycosaminoglycans238
The effect of lack of collagen X on fracture healing73
In vivo study of asporin polymorphic variants in chondrogenesis and degenerative skeletal diseases52
Abnormal cell cycle regulation and chondrocyte differentiation in transgenic mice expressing a schmid metaphyseal chondrodysplasia mutation in COL10A1.135
Behavioral Stress fails to Accelerate the Onset and Progression of Plaque Pathology in the Brain of a Mouse Model of Alzheimer's Disease88
Subcellular localisation of growth suppressor protein deleted in livercancer 2 (DLC2)181
Age-related degeneration of lumbar intervertebral discs in rabbits revealed by deuterium oxide-assisted MRI131
Mll-Een affects early lineage commitment of embryonic stem cells and causes maturation arrest of myeloid progenitors55
An examination of the regulation of gene expression using microarray and genomic resources189
Demonstration of calcium oxalate crystallization-enhancing activity of urinary macromolecules with a gel model62
UHRF1 double tudor domain and the adjacent PHD finger act together to recognize K9me3-containing histone H3 tail47
Subversion of innate antiviral immune response by Middle East respiratory syndrome coronavirus39
G-box binding coincides with increased Solanum melongena cysteine proteinase expression in senescent fruits and circadian-regulated leaves134
Role of neuregulin 1 type III in the generation of fate committed Schwann cells from bone marrow stromal cells36
Dual roles of Sox9 in transcriptional regulation in proliferating chondrocytes74
Profile of pro-inflammatory cytokines in bronchiectasis62
Presence of bone marrow-derived circulating progenitor endothelial cells in the newly formed lymphatic vessels162
Fusion of cranial ganglia cuased by the ectopic expression of Hoxb-3 gene in transgenic mice76
A comparative study of G-quadruplex aptamers against multiple protein targets263
Structural and functional evaluation of allogeneic MSC-based disc regeneration: implications of dosage and stage of degeneration with long-term follow-up65
Tracking commissural projections of vestibular neurons in a chondroitin, sulfate-enriched environment of the developing hindbrain66
Exploiting aptamer binding properties as a novel diagnostic technology for malaria46
An insertional mutation causing altered coat colour & vestibular dysfunction in mice64
Genetic variants associated with longer telomere length are associated with increased lung cancer risk among never-smoking women in Asia: a report from the female lung cancer consortium in Asia130
Targeting glutamate synthase for tuberculosis drug development72
The role of FOXM1 and Kaiso in non-small-cell lung carcinoma (NSCLC)106
SOX10 is abnormally expressed in aganglionic bowel of Hirschsprung's disease infants103
Cloning and characterization of a genomic fragment encoding abundant transcripts in anemic rat212
Genetic structure adds power to detect schizophrenia susceptibility at SLIT3 in the Chinese Han population1295
Mecahnisms of interferon induction and action172
Studies on the fibrinolytic activity in human tumour tissues: isolation and characterization of aplasminogen activator and an inhibitor in human tumour tissues191
Gene regulatory network inference from high frequency time series data37
Generation of Mutant Mouse Models for Studying the Role of Sox10 Functional Domains in Enteric Nervous System Development55
PRC1 cooperates with CLASP1 to organize central spindle plasticity in mitosis100
Impact of mutations of cartilage matrix genes on matrix structure, gene activity and chondrogenesis74
Collagen X deficiency exacerbates pathological calcification and impairs carilage remodeling in MGP-null mice61
FaSD-somatic: A fast and accurate somatic SNV detection algorithm for cancer genome sequencing data116
Depleting Suv39h1 methyltransferase rescues defective DNA repair and extends lifespan in progeria mouse model44
Internal ribosome entry site-mediated translational regulation of ATF4 splice variant in mammalian unfolded protein response191
Inorganic polyphosphate: from assay development to impact on cell function, signaling and gene experession209
Improving method for malaria detection – an aptamer approach57
Identification of regulatory elements directing control of Sox2 expression in mouse inner ear development56
Activation of TORC1 transcriptional coactivator through MEKK1-introduced phosphorylation and ubiquitination202
Inferring gene regulatory network from variable delay high temporal data107
Autosomal dominant and recessive osteochondrodysplasias associated with the COL11A2 locus106
Crystallization of urinary calcium oxalate at standardized osmolality and pH in the frozen state96
Association and functional analysis of ADAMTSS in lumbar disc degeneration99
Mitotic checkpoint control through phosphorylation and degradation47
Sensorineural deafness in a mouse model of campomelic dysplasia62
Aptamer library resampling26
Preparation of chitosan fibers for nerve regeneration63
In vivo study of Asporin, a genetic risk factor for osteoarthritis and degenerative disc disease57
Immobilized chondroitinase ABC I and II on chitosan beads improve axonal regrowth in CSPG-enriched astrocyte culture46
Pharmacokinetics, pharmacodynamics, long-term efficacy and safety of oral 1-deamino-8-D-arginine vasopressin in adult patients with central diabetes insipidus116
CRISPR/Cas9-mediated genome editing of Epstein–Barr virus in human cells175
Bioluminescent Detection of Nitroreductase Activity and Metals in Live Biological Samples35
identification of GTPase activating protein (GAP) specific for Rab27a64
Generation of induced pluripotent stem (iPS) cells from bone forming cells23
The effect of severity of degeneration on intervertebral disc regeneration by autologous mesenchymal stem cells61
Involvement of PDZD2 in regulating pancreatic beta cell function57
Association between bleomycin hydrolase and Alzheimer's disease in Caucasians88
Mitotic phosphorylation of PRC1 at Thr470 is required for PRC1 oligomerization and proper central spindle organization85
Preferential expression of alternatively spliced mRNAs encoding type II procollagen with a cysteine-rich amino-propeptide in differentiating cartilage and nonchondrogenic tissues during early mouse development87
KIF5B contributes to cell polarization during epithelial morphogenesis43
Transcriptional control of chondrocyte differentiation and their adaptation to ER stress in vivo58
Hearing and balance defects in a mouse model of campomelic dysplasia59
Inference of gene-phenotype associations via protein-protein interaction and orthology60
Analysis of mammalian gene expression noise in a negative-feedback loop76
Bioinformatics analysis of genetic and epigenetic factors regulating gene expression199
Depletion of annexin A5, annexin A6 and collagen X causes no gross changes in matrix vesicle-mediated mineralization, but lack of collagen X affects hematopoiesis and the Th1/Th2 response86
A method for morphological localization of cell and matrix vesicle-associated alkaline phosphatase61
Heparanse-syndecan-3 interaction in neurons of the adult spinal cord75
UHRF1 double tudor domain and the adjacent PHD finger act together to recognize K9me3-containing histone H3 tail67
Investigation of the homing ability of mesenchymal-like stem cells to sites of injury using a mouse model of IVD degeneration58
Effects of some charged amino acid mutations on the electron self-exchange kinetics of cytochrome b5121
Chitosan nerve conduits seeded with bone marrow stromal cell-derived Schwann cells enhance regeneration of transected sciatic nerves of adult rats100
Understanding the molecular impact of Sox9Y440X in campomelic dysplasia51
STK11 inhibits transcriptional activation of HTLV-I LTR by tax transactivator46
Structure and chromosomal DNA binding of the SWIRM domain133
Predisposition to familial osteoarthrosis linked to type II collagen gene93
Cell-intrinsic switch to the fate commitment of bone marrow-derived Schwann cells67
Discovery and application of DNA aptamers which specifically bind and inhibit WWP1 ubiquitin ligase in the osteoblast1320
In vivo analysis of SOX9 by conditionally knock-in of a mutant Sox9, Sox9Y440X, in the notochord69
Identification of therapeutic agents for the treatment of osteoarthritis with the application of high-throughput screening51
The role of nuclear membrane-type matrix metalloproteinase I (MT1-MMP) in cancer36
Analysis of multiple cardiac abnormalities of a knockout mouse mutant Hoxb3-lacZ51
Differential and overlapping expression of SOX2 and SOX9 in inner ear development67
In vitro generation of osteo-chondroprogenitors108
New selection and delivery approaches for nucleic acid aptamers against proteomic targets55
The study of extracellular matrix and stem cell niche in planarian84
Epidermal growth factor induced differential calcium signaling patterns in epidermoid cell lines68
Single-stranded oligonucleotide-mediated targeted gene repair in mammalian cells48
The role of Hox genes in otic vesicle patterning in Six1 regulatory pathway72
The duality of LysU, a catalyst for both Ap4A and Ap3A formation97
A novel profile hidden Markov model to predict microRNAs and their targets simultaneously129
The emerging role of autophagy in Parkinson's disease94
Assessing Clusters and Motifs from Gene Expression Data75
Phylogenetic analysis of planarian collagens and their roles in regeneration45
Hoxb1 cooperates with Gli to mediate sonic hedgehog signaling in the neurogenesis of hindbrain55
Peroxiredoxin-null yeast cells are genomically unstable86
Periostin interacts with sclerostin and inhibits its antagonistic effect on Wnt signalling124
A Novel Neural Response Algorithm for Protein Function Prediction68
Large-scale sequence analysis reveals novel human-adaptive markers in PB2 segment of seasonal influenza A viruses51
Identification of cis-elements for ethylene and circadian regulation of the Solanum melongena gene encoding cysteine proteinase197
DNA aptamers for molecular recognition in medical diagnostics25
The sortilin-related receptor SORL1 is genetically associated with Alzheimer’s Disease73
Cadmium affects retinogenesis during zebrafish embryonic development99
Loss of APD1 in Yeast Confers Hydroxyurea Sensitivity Suppressed by Yap1p Transcription Factor84
Prediction of quaternary assembly of SARS coronavirus peplomer101
Traditional Chinese medicine causing hepatotoxicity in patients with chronic hepatitis B infection: A 1-year prospective study102
A mammalian promoter model links cis elements to genetic networks97
Analysis of the murine Hox-2.7 gene: Conserved alternative transcripts with differential distributions in the nervous system and the potential for shared regulatory regions105
Expression of the SOX10 gene in bowel segments of normal and Hirschsprung's disease infants69
Hyperglycemia-Induced Protein Kinase Cβ2 Activation Induces Diastolic Cardiac Dysfunction in Diabetic Rats by Impairing Caveolin-3 Expression and Akt/eNOS Signaling68
Schwann cells derived from bone marrow stromal cells – in vitro study with dorsal root ganglia and in vivo study with peripheral nerve conduits85
Absence of association between Alzheimer disease and the -491 regulatory region polymorphism of APOE207
Coagulopathy after donor-hepatectomy: implications for postoperative analgesia111
ProteoMirExpress: inferring microRNA activities from mRNA and protein expression data53
Prokineticin-1 modulates proliferation and differentiation of enteric neural crest cells145
3′ Splicing variants of ret receptor tyrosine kinase are differentially expressed in mouse embryos and in adult mice128
Identification and characterization of long-range SOX9 enhancers in limb development88
Development of DNA aptamers against Treponema denticola164
Epigenetic inactivation of mir-34b/c in addition to mir-34a and DAPK1 in chronic lymphocytic leukemia60
dbPSHP: a database of recent positive selection across human population62
Characterization of the mouse myosin va cargo-binding domain178
Meeting report: Second Singapore Biologics Manufacturing Conference59
miR-BART5 is an anti-apoptotic miRNA encoded by EBV and inhibits PUMA to promote host cell survival57
Association between complement receptor1 polymorphisms and alzheimer's disease in southern Chinese population62
Human cathepsinG-cre mice for myeloid-specific gene targeting69
Repair of osteochondral defects with collagen-mesenchymal stem cell microspheres in a rabbit model70
REV7 is required for anaphase-promoting complex-dependent ubiquitination and degradation of translesion DNA polymerase REV170
Expression of homeobox gene HoxB5 is localized in the ganglia of human fetal and infant guts but not in Hirschsprung's disease gut227
Characterization of glycosaminoglycan-containing species synthesized by renal proximal tubular epithelial cells in culture49
Cloning, recombinant expression and digestion product characterization of chondroitinse ABC I and II58
The involvement of perineuronal semaphoring 3A and chondroitin sulfates in regulating maturation of the central vestibular circuitry52
MT1-MMP regulates early lymphocyte development through notchsignaling246
Studying the roles of conserved domains of the transcription factor Sox10 in neural crest development202
Generation of oligodendrocyte precursors from bone marrow stromal cells for remyelination therapy51
Proheparanase regulates synaptic function in the central vestibular circuitry48
An effective dose of valdecoxib in experimental mouse models of pain120
Disruption of the mouse Hoxb3 locus affects ventral body wall development53
Depletion of SUV39 ameliorates progeroid phenotypes and extends lifespan in accelerated aging mice39
Regulatory role of neuronal proheparanase in synaptic plasticity57
Increased basal insulin secretion in Pdzd2-deficient mice28
Upregulated proteoglycans synthesis in a human colon cancer cell line treated by hexamethylene bisacetamide59
The forkhead box M1 protein regulates the transcription of the estrogen receptor α in breast cancer cells110
Study the function of KIF5B in long bone development62
Maturation of otolith-related brainstem neurons in the detection of vertical linear acceleration in rats102
Development of a trans-kingdom expression system in cancer therapy64
Gain-of-function Hoxb3 mutation affects endothelin-1 pathway in craniofacial development84
Characterization of candidate tumor suppressor gene, DLC-1 in hepatocellular carcinoma88
ATP-dependent chromatin remodeling complex SWI/SNF in cardiogenesis and cardiac progenitor cell development.92
From essential to persistent genes: a functional approach to constructing synthetic life68
Change in NECL family expression profile in cell culture model when NECL1 is knocked down45
Signaling mechanisms of melatonin in antiproliferation of hormone-refractory 22Rv1 human prostate cancer cells: Implications for prostate cancer chemoprevention106
A Comparison of genomic Instability in Laminopathy-specific Lamin A Mutations51
Cholesterol and genetics of Alzheimer's disease47
The role of heparanase in synaptic plasticity at the hippocampus187
Proteomic profiling identifies the SIM-associated complex of KSHV-encoded LANA103
Pseudomonas aeruginosa adherence to human basement membrane collagen in vitro104
Studies of kappa opioid receptor in mediating stress response via the phospholipid C pathway41
Chondroitin sulfates in the developing rat hindbrain confine commissural projections of vestibular nuclear neurons150
The regulatory role of proheparanase in synaptic plasticity at the hippocampus76
Optimization of guide RNA scaffold design for multiplexed gene editing21
Inactivation of human MAD2b in nasopharyngeal carcinoma cells leads to chemosensitization to DNA-damaging agents129
Genome wide linkage association analysis reveals PTPN21 contributes to Elk-1 dependent NRG3 expression, enhances neuronal survival in embryonic cortical neurons54
Novel Profile Hidden Markov Model to Predict MicroRNAs and their Targets Simutaneously84
Suppression of lung tumor growth and metastasis in mice by adeno-associated virus-mediated expression of vasostatin147
Transcriptional regulation of p16INK4a expression by the forkhead box transcription factor FOXM1260
Unraveling the molecular basis of the bacteriophage lambda-encoded recombination system in E. coli63
Detection of extracellular matrix degradation in intervertebral disc degeneration by diffusion magnetic resonance spectroscopy121
Stimulation of IKK-γ oligomerization by the human T-cell leukemia virus oncoprotein Tax85
Alcanivorax hongdengensis sp. nov., an alkane-degrading bacterium isolated from surface seawater of the straits of Malacca and Singapore, producing a lipopeptide as its biosurfactant102
Genome-wide association study of adolescent idiopathic scoliosis in southern Chinese78
The role of Indian Hedgehog in chondrocyte hypertrophy43
Embryonic XMab21l2 expression is required for gastrulation and subsequent neural development88
Sox10 is essential for gliogenesis of the cochleo-vestibular ganglion68
Exploring the function of genetic variants in the non-coding genomic regions: approaches for identifying human regulatory variants affecting gene expression194
Investigating epistasis in degenerative disc disease59
Pre-B-cell leukemia homeobox 1 (PBX1) shows functional and possible genetic association with bone mineral density variation118
Rapid labeling of intracellular His-tagged proteins in living cells165
Phenotypic changes of stem cells after culture in the intervertebral disc niche48
Portable Two-Way Riboswitches: Design and Engineering103
Chondroitin Sulfate Moieties Restrict Migration of Cranial Motor Neurons in the Developing Hindbrain of Rats60
SPS: a simulation tool for calculating power of set-based genetic association tests92
Understanding the function of the SEDL gene and the molecular pathogenesis of spondyloepiphyseal dysplasia tarda52
Association of the Taq I allele in vitamin D receptor with degenerative disc disease and disc bulge in a Chinese population216
Polymorphisms of the ACE2 and CD13 (ANPEP) genes, and susceptibility to SARS coronavirus infection in Chinese from Hong Kong117
Factors underlying improved efficacy of chondroitin sulphate lyases in overcoming chondroitin sulphate barriers for nerve repair and regeneration64
GWAS3D: Detecting human regulatory variants by integrative analysis of genome-wide associations, chromosome interactions and histone modifications95
Age-related changes versus degenerative disc disease100
Interferon-γ increases intracellular calcium and inositol phosphates in primary human thyroid cell culture99
Extracellular Matrix and Membrane-type Matrix metalloproteinase in Development and Diseases21
Defects in early B lymphocyte development in Zmpste24⁻′⁻ mice192
ChIP-Array: Combinatory analysis of ChIP-seq/chip and microarray gene expression data to discover direct/indirect targets of a transcription factor159
Induction of cells with osteo-chondrogenic potential by transcription factor-mediated reprogramming process204
Osteogenic differentiation of alginate microencapsulated mesenchymal stem cells for bone formation: An in vitro study108
In silico mapping of quantitative trait loci affecting bone mineral density in mice69
Dissecting the transition from hypertrophic chondrocyte to osteoblast in skeletal development and growth51
The role of Hoxb3 in mammalian hindbrain patterning and craniofacial development58
Correlating protein structure with disease - understanding the mechanism of SEDT74
Gli3 repressor is required to mediate the timing of mammalian cochlear hair cell differentiation81
Identification of novel FBN1 and TGFBR2 mutations in 65 probands with Marfan syndrome or Marfan-like phenotypes96
Transgenic mice expressing human epidermal growth factor show stunted growth99
MT1-MMP regulates FGFR signalling in development40
Planar cell polarity breaks bilateral symmetry by controlling ciliary positioning1215
Perturbation of Hoxb5 signalling in vagal neural crest cells causes defective development of the enteric nervous system78
Immobilization of chondroitinase ABCI on chitosan beads to improve axonal regrowth in CSPG-enriched astrocyte culture121
Resveratrol rescues Sirt1-dependent adult stem cell decline and alleviates progeroid features in laminopathy-based progeria121
The role of Hox genes in otic vesicle patterning and morphogenesis72
Sox2 is required for sensory organ development in the inner ear63
Computational approaches for protein functions and gene association networks212
Perinatal perturbation of NMDA receptor in the vestibular nucleus attenuates cerebellar function56
Maturation profile of ionotropic glutamate receptors in central vestibular neurons of rats59
Bilateral otolith contribution to spatial coding in the vestibular system.111
MBEToolbox: A Matlab toolbox for sequence data analysis in molecular biology and evolution96
The immunologic and metabolic features of Chinese patients with a typical diabetes mellitus55
Chondroitinase ABC isoforms cooperate to enhance axonal growth68
Targeting heparan sulfate/syndecan-1 in attempts to restore the balance between neutrophil elastase and anti-elastase in bronchiectasis90
Chondroitinase may be involved in providing a permissive environment for nerve regeneration64
A role of proheparanase in synaptic plasticity41
Chemical biology104
Sox10 mutation affects enteric neural crest cell migration in a cell autonomous manner77
Characterization of a physiological 62-kDa protein substrate for ganglioside-stimulated protein kinase in central nervous systemmyelin213
Kinesin-1 is necessary for chondrocyte cytokinesis133
Heparanase colocalizes with syndecan-3 in neurons of normal adult spinal cord56
Expression and electrophysiological studies of secretin in the rat hypothalamic paraventricular nucleus87
Effect of impaired matrix turnover on differentiation of intervertebral disc cells40
The roles of the PDZ-containing proteins bridge-1 and PDZD2 in the regulation of insulin production and pancreatic beta-cell mass110
Double-stranded RNA-binding protein PACT is a potent activator of RIG-I-dependent innate antiviral response66
Chinese patients with sporadic Hirschsprung's disease are predominantly represented by a single RET haplotype.129
In-vitro effect of bronchiectatic sputum sol on ICAM-1 expression in bronchial epithelial cells63
Suppression of type I interferon production by human T-cell leukemia virus type 1 Tax oncoprotein52
Perturbed SUFU-GLI-SOX10 regulatory network underlies defective enteric nervous system development and Hirschsprung disease72
Sox2 dosage defines the specification and survival of sensory neurons in the inner ear56
Novel complex disease allele mutations in cleidocranial dysplasia patients51
Construction of new DNA vectors based on promoters of Epstein-Barr virus-encoded small RNAs for expression of small hairpin RNAs in mammalian cells59
Genetic variation in the COL9A2 gene and its association to intervertebral disc abnormalities in Southern Chinese101
Investigation of Antibody-Dependent Enhancement (ADE) of SARS coronavirus infection and its role in pathogenesis of SARS100
Ultrahigh resolution mass spectrometry-based metabolic characterization reveals cerebellum as a disturbed region in two animal models.68
Activation of nuclear factor kappa B by androgen receptor splice variant AR-V7 in 22Rv1 Castration-resistant prostate cancer cells1377
Study of recombineering technology in Salmonella and its applications196
Kinesin-1 in pancreatic beta cell and renal epithelial cell174
Salvianolic acid B inhibits Aβ fibril formation and disaggregates preformed fibrils and protects against Aβ-induced cytotoxicty151
Effect of antibiotics on sputum inflammatory contents in acute exacerbations of bronchiectasis128
In vitro selection of DNA aptamers binding H5N1 Virus nucleoprotein54
Functional roles of type IIA procollagen47
Transcriptional regulation of mitotic checkpoint gene MAD1 by p5363
The developmental origin of osteoblasts in endochondral bone165
Transcriptional regulation of transferrin receptor expression during phorbol-ester-induced HL-60 cell differentiation. Evidence for a negative regulatory role of the phorbol-ester-responsive element-like sequence96
Nicastrin binds to membrane-tethered Notch87
A novel bunyavirus causing fever and thrombocytopenia: More questions than answers88
A study of proteoglycan production during suppressed cell proliferation of a human colon carcinoma cell line183
Confronting the challenges of biochemistry teaching and learning in the medical curriculum68
An in vivo analysis of specificity of gene transactivation by SOX proteins197
Increased Col10a1 expression is not causative for the phenotype of Phex-deficient Hyp mice55
Glutamatergic transmission in the vestibular nucleus is critical to the formation of spatial topography and acquisition of spatial navigation in rats behaviour54
Adenoviral delivery of RNA decoys restores expression of proapoptotic protein PUMA in nasopharyngeal carcinoma cell by silencing of epstein-barr virus-encoded antiapoptotic miR-BART560
Comparative studies on the mouse and human type II collagen genes186
New approaches for therapeutic aptamer selection and delivery53
Hirschsprung's disease98
Investigating the role of SOX9 in human neural stem cells277
Allogeneic mesenchymal stem cell transplanation into the intervertebral disc: effect of serverity of degernation and cell number on regeneratiion114
Impact of activating ADAMTS-5 in cartilage-related degenerative disorders62
Adipocyte fatty acid-binding protein is a plasma biomarker closely associated with obesity and metabolic syndrome134
Signaling mechanisms involved in the inhibition of human prostate cancer cell proliferation by Saw Palmetto (Serenoa repens)70
Towards remyelination therapy with oligodendrocyte precursor derivation from bone marrow stromal cells65
Differentiation of notochordal-like cells from human pluripotent stem cells133
The role of Sox2 and Sox18 in mouse hair development47
Transcriptional regulators of col10al in chondrocyte differentiation191
Secreted PDZ domain-containing protein 2 (sPDZD2) exerts insulinotropic effects on INS-1E cells via a protein kinase A - dependent mechanism57
Cholesterol biosynthesis is a potential pathway involved in the degeneration of the annulus fibrosus74
Integrated bioinformatics analysis of genetic, expression and interaction data to understand the molecular mechanisms of Alzheimer's disease204
ChIP-Array: Gene Regulation Network Construction from ChIP-seq/chip and mRNA expression data52
Studies of oxalate transport across filter cultures of renal proximal tubular epithelial cells42
Strontium promotes osteogenic differentiation of mesenchymal stem cells through the Ras/MAPK signaling pathway122
Altered Sox10 gene expression in aganglionic bowel of Hirschsprung's disease patients74
Tensin2 variant 3 is associated with aggressive tumor behavior in human hepatocellular carcinoma102
Inner ear abnormalities in the novel transgenic mouse mutant, yellow submarine (ysb)72
The role of Pax6 in beta-amyloid-induced neuronal apoptosis64
Use of chondroitin sulphate exolyase and endolyase to decrease axon-restrictive chondroitin sulphates in neural environments68
Impact of intracellular clearance of unfolded proteins on chondrocytes cell fate67
Double-stranded break can be repaired by single-stranded oligonucleotides via the ATM/ATR pathway in mammalian cells381
Neuregulin 1 type III in the switch of bone marrow stromal cells to fate-committed Schwann cells54
PHOX2B gene is associated with Hirschsprung's disease84
Chondroitin sulfate proteoglycans produced by astrocytes modulate neuron adhesion and neurite outgrowth58
Use of tandem mass spectrometry as a tool for proteomics studies in aging and degeneration processes of the intervertebral disc75
Ptpn21, a positive mediator which promotes ErbB4 and suppresses cell survival62
Identification of 'Stemness' genes by integrating differentially expressed genes from multiple stem cell microarray databsets65
Wholemount in situ hybridizationa nd transgenic analysis of the mouse Hoxb-3 gene51
Mechanism of genomic instability in Prelamin A based premature ageing168
The region on Xenopus GATA-1b transcript responsible for its anti-neurogenic activity175
PU.1 can recruit BCL6 to DNA to repress gene expression in germinal center B cells83
Two-dimensional assays of peptide fragments54
Visualizing the proteome of Escherichia coli: An efficient and versatile method for labeling chromosomal coding DNA sequences (CDSs) with fluorescent protein genes124
FGF receptor-4 (FGFR4) polymorphism acts as an activity switch of a membrane type 1 matrix metalloproteinase - FGFR4 complex210
The Kappa-opioid receptor specific agonist U50488H induces mitochondrial stress in cultured human cancer cells98
Mechanical force controlled epithelial morphogenesis37
Polymorphisms of CR1, CLU and PICALM confer susceptibility of Alzheimer's disease in a southern Chinese population117
Derivation of stable Schwann cells from human bone marrow stromal cells68
Dual actions of brain-derived neurotrophic factor on GABAergic transmission in cerebellar Purkinje neurons128
Transcriptome of the human intervertebral disc in health and disease65
The novel mouse [gamma]A-crystallin mutation leads to misfolded protein aggregate and cataract178
Change in perineuronal net of rat vestibular nuclear neurons in development and in injury72
Common colorectal cancer risk alleles contribute to the multiple colorectal adenoma phenotype, but do not influence colonic polyposis in FAP.77
Use of chondroitin sulphate lyase subtypes to overcome molecular barriers of reactive glia: implication for nerve regeneration65
EpiRegNet: Constructing epigenetic regulatory network from high throughput gene expression data for humans123
Dissecting the mechanism of binding between polyphosphate and polyphosphate kinase 258
Development of Salmonella-mediated Oral Vaccine against Avian Influenza Viruses H5N163
Separate effects of urinary chondroitin sulphate and heparan sulphate on the crystallization of urinary calcium oxalate: Differences between stone formers and normal control subjects113
Genetic risks for chronic periodontitis: preliminary data of a genome-wide association study99
Maturation of canal-related brainstem neurons in the detection of horizontal angular acceleration in rats161
Effects of fluoxetine on the restoration of plasticity in young adult vestibular nucleus52
Exchange protein directly activated by cAMP 1 is involved in β3-adreneric induction of brown adipose tissue in white adipose tissue346
The biological effect of fenretinide in nasopharyngeal carcinoma cells76
Abnormal enteric ganglia development in a Sox10 mouse mutant generated by gene targeting71
Mechanisms associated with IL-6-induced up-regulation of Jak3 and its role in monocytic differentiation179
Analysis of transgenic mice with ectopic Hoxb-3 expression in rhombomere 4197
High-throughput loss-of-heterozygosity study of chromosome 3p in lung cancer using single-nucleotide polymorphism markers147
Delayed tooth eruption in membrane type-1 matrix metalloproteinase deficient mice122
A study on the male accessory sex gland secretions of the golden hamster Mesocricetus auratus)187
Apolipoprotein(a) polymorphism in Hong Kong Chinese: genetic and hormonal effects69
Nitrogen plasma modified nickel titanium alloy for orthopaedic implantation: long-term in vivo study72
Developmental Genomics and Skeletal Research51
Promoting deep learning in biochemistry by diversifying assessment strategies - experience at the University of Hong Kong1221
Aptamer-mediated inhibition of mycobacterium tuberculosis polyphosphate kinase 2273
The use of a mouse model to understand the pathogenesis of campomelic dysplasia caused by the human mutation, Sox9Y440X52
Epstein-Barr virus encodes an antiapoptotic microRNA to inhibit PUMA and promote tumor cell survival52
Corticofugal modulation of acoustically induced Fos expression in the rat auditory pathway189
Roles of Prokineticin-1 in enteric nervous system development74
Proficiency of DNA repair networks in stem cells as determinants of aging70
Correlation of clinical and molecular biological abnormalities in osteogenesis imperfecta.85
Characterization of human bone marrow stromal cells following differentiation into Schwann cells46
Inhibition of prostate cancer cell growth by human sPDZD2 protein73
Cerebellar defects in Pdss2 conditional knockout mice during embryonic development and in adulthood160
Axonal trajectories of the vestibular nuclei in the developing rat embryo104
Fate of growth plate hypertrophic chondrocytes: Death or lineage extension?67
The role of SOX9 in ear development54
Chondroitinase ABC-I and -II crosslinked chitosan beads improve axonal regrowth in CSPG-enriched astrocyte culture153
Developing three dimensional culture system for Notochordal cells71
Perineuronal chondroitin sulfates regulate vestibular plasticity during development48
Depleting the methyltransferase Suv39h1 improves DNA repair and extends lifespan in a progeria mouse model149
CTCF controls HOXA cluster silencing and mediates PRC2-repressive higher-order chromatin structure in NT2/D1 cells70
Investigating epistasis in degenerative disc disease75
Collagen gene expression in embryonic stem cells and in mouse development248
Site-directed mutagenesis of human type X collagen. Expression of α1(X) NC1, NC2, and helical mutations in vitro and in transfected cells54
Substitution of arginine for glycine 664 in the collagen α1(I) chain in lethal perinatal osteogenesis imperfecta. Demonstration of the peptide defect by in vitro expression of the mutant cDNA95
Latent membrane protein 1 suppresses RASSF1A expression, disrupts microtubule structures and induces chromosomal aberrations in human epithelial cells150
Synaptic Roles of Cdk5: Implications in Higher Cognitive Functions and Neurodegenerative Diseases78
The Mll-Een knockin fusion gene enhances proliferation of myeloid progenitors derived from mouse embryonic stem cells and causes myeloid leukaemia in chimeric mice140
A database of genetic variants in microRNA genes and their putative functional roles in gene regulation53
Proteolytic cleavage of PDZD2 generates a secreted peptide containing two PDZ domains150
Development of inhibitory nucleic acid aptamers against aggrecanase for therapeutic applications235
Combating prostate diseases with ethnobotanical drugs: inhibition of prostate cancer cell proliferation by SawPalmetto (Serenoa repens) extracts257
Roles of Neuregulin 1 Type III in the Ex Vivo Generation of Fate Committed Schwann cells from Bone Marrow Stromal Cells68
Fate commitment of bone marrow-derived Schwann cells is guided by Notch and ErbB signaling39
Collagen X function and regulation of gene expression78
The roles of Hoxb3 and Jag1 in mediating branchial arch defects in Six1-Eya1 associated Branchio-Oto-Renal Syndrome59
Fate and properties of notochordal descendent cells in the intervertebral disc: implication to disc degeneration60
Prokineticin-1 (Prok-1) works coordinately with glial cell line-derived neurotrophic factor (GDNF) to mediate proliferation and differentiation of enteric neural crest cells141
The Role of SOX10 in the Enteric Neural Crest Development79
A fast and accurate model to detect germline SNPs and somatic SNVs with high-throughput sequencing356
A mutant gA-crystallin leads to cataractogenesis through the unfolded protein response60
Neural-specific cis-acting and trans-acting regulation of the mouse Hoxb-3 gene during embryogenesis81
The presence of serotonin in cigarette smoke - a possible mechanistic link to 5-HT-induced airway inflammation64
Physical status of mitochondrial aspartate aminotransferase in serum and the role of alpha 2-macroglobulin in its clearance184
Genetic risk prediction for common diseases using genetic markers from Genome-Wide Association studies43
An essential role for Sox2 in sensory organ development in the mammalian inner ear50
Purification and identification of sclerostin interacting partners: steps towards Osteoporosis Therapy with aptamer-based inhibitors77
Transcription and translation of phloem protein (PP2) during phloem differentiation in Cucurbita maxima95
The branchial Hox code and its implications for gene regulation, patterning of the nervous system and head evolution84
Creation of biological patterns controlled by synthetic genetic circuits15
Generation and analysis of transgenic mice expressing collagen X with a mutation in the NC1 domain205
A highly polymorphic region 3′ to the human type II collagen gene89
Limiting histone ubiquitylation selectively promotes homologous recombination DNA repair40
N-linked glycosylation is required for optimal proteolytic activation of membrane-bound transcription factor CREB-H88
The potential of umbilical cord derived mesenchymal stem cells in intervertebral disc repair78
SOX9 induces and maintains neural stem cells255
Abnormal enteric ganglia development in transgenic mice with ectopic expression of mutant Sox10 in the vagal neural crest.113
Early postnatal perturbation of inhibitory transmission in the vestibular nucleus governs the expression of spatial map and spatial navigation behaviors45
Requirement of CRTC1 coactivator for hepatitis B virus transcription139
Lamin A/C, laminopathies and premature ageing440
Role of isthmin in chick spinal cord development42
Activation of NLRP3 inflammasomes by severe acute respiratory syndrome coronavirus 3a protein59
Induction of osteo-chondroprogenitors formation by transcription-factor mediated reprogramming process58
Role of cadherin 2 in intervertebral disc homeostasis49
Regulation of AMPA-type glutamate receptor trafficking by proheparanase in synaptic plasticity84
Partial characterization of rat and pufferfish insulin receptor genes and identification of sequences regulating the alterative splicing ofinsulin receptor pre-mRNA160
Functional analyses on TGF{221}/BMP signaling and type IIA procollagenin inner ear development195
Use of Schwann cell-seeded nanofiber as nerve conduit144
Phospho-JNK and phospho-jun are upregulated following hypoxic-ischaemic encephalopathy69
Csi1p recruits alp7p/TACC to the spindle pole bodies for bipolar spindle formation73
Salvianoli acid B inhibits hydrogen peroxide -induced endothelial cell apoptosis through regulating P13K/Akt signaling62
Similarities and differences in apoptosis induced by staurosporine and wortmannin54
Bioinformatic studies of gene regulation involving SOX9 and HOXB3 withreference to craniofacial development and other processes179
Potential roles of PDZD2 in prostate cancer pathogenesis76
Time course of cortically induced fos expression in auditory thalamus and midbrain after bilateral cochlear ablation120
Changes in the proteome of the human intervertebral disc in aging and degeneration84
Regulation of p16INK4a expression by the forkhead transcription factor FOXM165
Characterization of a Sox10 mouse mutant generated by gene targeting90
Identification of chemical compounds for the treatment of intervertebral disc degeneration with the application of high-throughput screening52
Nano-structure of collagen fibrils in human intervertebral discs and its correlation with the tissue mechanics81
Is there a role for Hedgehog genes in Hirschsprung's diseases?71
Evidence for physical interaction between CHOP/Gadd153 mRNA and specific intracellular proteins47
Epigenetic inactivation of the MIR34B/C in multiple myeloma236
Bone marrow stromal cell-derived oligodendrocyte precursor cells: a new perspective in CNS myelin repair63
Mesenchymal stem cell-based repair of articular cartilage with polyglycolic acid-hydroxyapatite biphasic scaffold129
Molecular characterization of suppression of hepatitis B virus transcription by hepatitis C virus core protein86
Craniofacial abnormalities caused by ectopic expression of Hoxb3 revealed a network of gene interactions.55
Fine mapping candidate loci for nasopharyngeal carcinoma (NPC) in southern Chinese specifically linked to EBV aetiopathogenesis115
Type IIA procollagen: a positive regulator of nodal signaling during early embryogenesis46
Functional characterisation reveals PTPN21 as a positive mediator of NRG3, a potential risk factor in Schizophrenia86
Injury-associated changes in the disaccaride composition of chondroitin sulphates in post-crush sciatic nerves of adult guinea pigs56
The role of Indian hedgehog in chondrocyte hypertrophy33
Development of Three-Dimensional Culture System for Maintenance of Bovine Nucleus Pulposus Cells82
Comparison of fatty-acid-binding protein 4 and adiponectin levels in infrapatellar fat pad and subcutaneous adipose tissue, synovial fluid and plasma in subjects with knee osteoarthritis180
Genetic study of lumber disc degeneration326
Role of matrix remodeling in endochondral bone formation46
Activation of protein secretory pathway by fusion oncoprotein FUS-CREB3L2 in low-grade fibromyxoid sarcoma56
Characterization of yeast peroxiredoxin tsa1p in DNA damage response212
SIRTain regulators of premature senescence and accelerated aging.75
Chemical cross-linking of hemoglobin H. A possible approach to introduce cooperativity and modification of its oxygen transport properties103
Bridging of transected sciatic nerves of adult guinea pigs with soluble heparan sulfates speeds up nerve regeneration47
A frameshift mutation results in a truncated nonfunctional carboxyl-terminal Proα1(I) propeptide of type I collagen in osteogenesis imperfecta102
Dynamics of chondroitin sulfotransferase expression for cranial motor neuron migration in rat hindbrain development54
Visualizing the Proteome Escherichia coli by Recombineering Technology58
An updated metabolic view of the Bacillus subtilis 168 genome113
Structure of RPA32 bound to the N-terminus of SMARCAL1 redefines the binding interface between RPA32 and its interacting proteins.102
Role of ATM signaling in PALB2-dependent DNA damage responses76
The pathological roles of BART miRNAs in nasopharyngeal carcinoma.62
The role of Hox genes in dorsoventral patterning and morphogenesis of inner ear65
The adaptor function of TRAPPC2 in mammalian trapps explains TRAPPC2-associated sedt and TRAPPC9-associated congenital intellectual disability123
Functional regulation of the forkhead box M1 transcription factor by Raf/MEK/MAPK signaling237
Differential and overlapping expression of SOX2 and SOX9 in inner ear development54
ProF: neural response based protein function prediction algorithm61
Epigenetic regulation in laminopathy-based premature aging235
Functional asymmetry in the lysyl-tRNA synthetase explored by molecular dynamics, free energy calculations and experiment52
An externally fixed femoral fracture model for mice103
Suppressor of fused (Su(fu)) plays domain specific function in orchestrating the maintenance and differentiation of hindbrain neural progenitor pools78
Protein flexibility and intrinsic disorder75
Function of 14-3-3 proteins76
Analysis of abnormal craniofacial and ear development of a transgenic mutant with ectopic hoxb3 expression222
Mutations in the open reading frame of the β-site APP cleaving enzyme (BACE) locus are not a common cause of Alzheimer's disease71
Studies of the regulation of mouse Hoxb-3 gene176
Delayed induction of proinflammatory cytokines and suppression of innate antiviral response by the novel Middle East respiratory syndrome coronavirus: implications for pathogenesis and treatment234
The gene expression, binding properties and intracelular signal transduction of kappa-opioid receptor in non-neuronal cells188
Type IIA procollagen and the regulation of nodal signaling272
Collagen genes and inherited connective tissue disease158
Effects of Surface Negatively Charged Amino Acid Mutation on Binding between Cytochrome b 5 and Cytochrome c97
Kinesin-1 is necessary for cytokinesis in chondrocytes58
Perturbation of the plasticity at GABAeric synapses in the vestibular nucleus during a critical period impacts on the thalamic spatial network and navigation behavior60
Viral and cellular regulators of Type I interferon production47
Sirt1, end of the story in aging?47
Impaired endochondral ossification and angiogenesis in mice deficient in membrane-type matrix metalloproteinase I134
Widespread occurrence of ganglioside-stimulated protein kinase in animal brains53
Formation of new patterns by programming cell motility26
PCR amplification of alleles at locus D17S5: population genetic study in Hong Kong Chinese and detection of allelic loss in patients with hepatocellular carcinoma59
Compression induced alignment and elongation of human mesenchymal stem cell (hMSC) in 3D collagen constructs is collagen concentration dependent74
Effects of protein kinase modulators on transferrin receptor expression in human leukaemic HL-60 cells116
Regulatory role of proheparanase with peri-synaptic heparan sulfate proteoglycan and AMPA-type glutamate receptor in synaptic plasticity72
FastPval: A fast and memory efficient program to calculate very low P-values from empirical distribution150
Dual-functional encapsulated-cell therapy implant for retinal diseases: sustained intraocular GDNF delivery and controlled termination32
The role of diadenosine polyphosphates in neurotransmission; Regulation of dendritic excitation in hippocampus by non-hydrolysable diadenosine polyphosphate analogue50
Investigation of the functions and specificities of mouse myosin va isoforms66
Chinese B thalassaemia: DNA polymorphisms andspecific mutations246
Laminopathy-based premature Aging27
Expression of chondroitin sulfotransferase in cranial motor neurons for cell migration in rat embryonic hindbrain39
Functional characterization of the liver-enriched transcription factor CREB-H95
REAGENTS FOR DETECTION OF HYPOCHLOROUS ACID78
Functional Analyses of Type IIA Procollagen in Mouse Inner Ear Development44
Collagen-mesenchymal stem cell microspheres for cartilage tissue engineering131
The role of PERK pathway in adaptation of hypertrophic chondrocytes to ER stress84
Ubiquitin-dependent regulation of translesion polymerases83
EpiRegNet: constructing epigenetic regulatory networks from high throughput gene expression data for humans99
G-quadruplex aptamers inhibit sclerostin for osteoporosis therapy96
Upregulation of nitrated chondroitin sulfate proteoglycans in reactive astrocytes and cerebrospinal fluid of patients with amyotrophic lateral sclerosis49
In-Vivo Study of Asporin in Cartilage Tissues85
Acacetin causes a frequency- and use-dependent blockade of hKv1.5 channels by binding to the S6 domain202
Whole exome sequencing identifies a novel mutation in the transglutaminase 6 gene for spinocerebellar ataxia in a Chinese family.124
Detecting exon deletions and duplications of the DMD gene using Multiplex Ligation-dependent Probe Amplification (MLPA)196
In vivo functional analysis of SOX9 by conditional expression of a mutant SOX9, SOx9Y440X68
A Novel Sox10-NGFP mouse model of Waardenburg-Hirschsprung Syndrome95
An EcoRI RFLP in the human α2 (XI) (COL 11A2) gene111
Effects of protein kinase activators and inhibitors on transferrin receptor expression in human leukemic HL-60 cells66
An insertional mutation affecting coat colour and vestibular function in mice43
Stem Cells - Whats and Hows26
Roles of spike protein in the pathogenesis of SARS coronavirus.67
Vitamin D and its action on isolated enterocytes from rats170
Defining the effects of hypoxia on glycogen metabolism in cancer cells52
(iv) Genetics of disc degeneration145
Lethal perinatal osteogenesis imperfecta due to a type I collagen α2(I) gly to arg substitution detected by chemical cleavage of an mRNA:cDNA sequence mismatch106
Ectopic expression of Hoxb3 in the hindbrain causes abnormal ear development49
Purification and characterization of ornithine decarbozylase fromtetrahymena thermophila221
ErbB receptor modulation controls the fate commitment of bone marrow-derived Schwann cells57
Integration of factors and pathways facilitating chondrocyte adaptation to ER stress59
Improvement in detection of missing heritability and genetic risk prediction in genome-wide association studies using 1000 genomes-based imputation54
Neural chondroitin sulfates differ from heparan sulfates in effects on regrowth of transected sciatic nerves of adult guinea pigs57
A cascade of irx1a and irx2a controls shh expression during retinogenesis107
In vitro aptamer selection against the SARS coronavirus helicase and their intracellular delivery49
Genomic orgonization and characterization of a three-gene rat adult b-globin haplohype86
FOXM1b, which is present at elevated levels in cancer cells, has a greater transforming potential than FOXM1c88
PDZD2, a candidate for brachydactyly type A1, encodes a secreted protein that negatively modulates hedgehog signaling239
Heparan sulfate proteoglycans complexed neutrophil elastase differentially modulate inhibition by physiological anti-elastases (Observations in bronchial secretions of patients with bronchiectasis)49
Novel plasma-implanted shape memory alloys in orthopaedics50
Hypoxia Inducible Factor-1-alpha in Healthy and Diseased Periodontium85
Chromosome 10 and 12 loci for late-onset Alzheimer’s Disease: genetic linkage and case-control association studies57
N-linked glycosylation is required for optimal proteolytic activation of membrane-bound transcription factor CREB-H191
Genetic Analyses of Terminal Differentiation of Hypertrophic Chondrocytes58
Involvement of neuregulin 1 type III in the EX Vivo generation of fate committed schwann cells from bone marrow stromal cells53
Bio-coordination of bismuth in Helicobacter pylori revealed by immobilized metal affinity chromatography115
Expression of Trk receptors in otolith-related neurons in the vestibular nucleus of rats113
Erratum: Nesprin-2 giant safeguards nuclear envelope architecture in LMNA S143F progeria cells (Human Molecular Genetics (2007) vol. 16 (23) (2944-2959) 10.1093/hmg/ddm255)86
Functional studies on sedlin and its involvement in spondyloepiphysealdysplasia tarda259
The molecular and cellular basis of exostosis formation in hereditary multiple exostoses112
Detection of plasmodium falciparum lactate dehydrogenase by aptamer-nanoparticle conjugates136
Genomic sequence of a Sprague - Dawley rat β-globin gene66
Mapping of chondroitin sulfate glycoform and chondroitin 6-sulfotransferase in neuroepithelial boundaries of mouse embryos66
Characterization of heparan sulphate proteoglycan recovered from cultures pf human bronchial epithelial cells61
Characterization of a novel MAD1 isoform, MAD1β, in hepatocellular carcinoma66
Proteomic characterization of human serum proteins associated with the fat-derived hormone adiponectin109
Mitotic arrest deficient 2 expression induces chemosensitization to a DNA-damaging agent, cisplatin, in nasopharyngeal carcinoma cells78
The regulation of FGF signaling by MT1-MMP in calvarial osteogenesis54
Wnt regulation of planar cell polarity (PCP)1070
Use of Bicistronic Constructs to Over-Express the Epidermal Growth Factor Precursor57
Role of autophagy in chondrocyte differentiation55
Hypertrophic chondrocytes survive ER stress by maintaining glycolysis and mitochondrial membrane poloarity42
Epigenetic reprogramming of fibroblasts into osteo-chondroprogenitors82
The potential role of Simian Virus 40 polyA sequence (SV40 polyA) to mediate stress-inducible mRNA translation106
Using Polyanionic Heparin Mimetics for the treatment of COPD69
Inhibition of SARS coronavirus helicase by bismuth complexes126
The proteomics of protein misfolding in chondrocytes45
Dendritic cell podosomes are protrusive and invade the extracellular matrix using metalloproteinase MMP-14168
Proteomics analysis of the human intervertebral disc reveals potential fibrotic events in degeneration75
Identification and characterization of long-range SOX9 enhancers in limb development76
SLAM-associated protein as a potential negative regulator in Trk signaling88
Salt-inducible kinases function as a host restriction to human T-cell leukemia virus type 1 transcription235
Identifying transcriptional regulatory elements directing hypertrophic chondrocyte-specific expression of Col10a154
Global landscape of histone modifications contributes to cellular identity determination by affecting gene expression dynamics58
Cyp26b1 mediates differential neurogenicity in axial-specific populations of adult spinal cord progenitor cells113
Mutations of SOX10 gene in Hirschsprung's disease patients with and without Waardenburg-Shah Syndrome62
The interplay between multiple enhancer and silencer elements defines the pattern of decapentaplegic expression76
EATdb: a database of human enhancers and their putative targets172
Novel nuclear partnering role of EPS8 with FOXM1 in regulating cell proliferation248
Determination of protein biomarkers by microflow injection aptamer-coated piezoelectric quartz crystal biosensor54
Functional analysis of SM22β by targeted gene deletion in mice62
Predicting the establishment of hair follicle patterns in the developing mouse57
Some effects of hyperbaric oxygen on brain metabolism185
Quantitative characterization of mesenchymal cell aggregation process47
Combined prokaryotic–eukaryotic delivery and expression of therapeutic factors through a primed autocatalytic positive-feedback loop108
Genetic analysis of Alzheimer's disease associated genes: a perspective from abnormal cholesterol metabolism269
Candidate gene study of polymorphisms of interleukin-1 in lumbar disc degeneration91
CDX-1 and CDX-2 are expressed in human colonic mucosa and are down-regulated in patients with Hirschsprung's disease associated enterocolitis158
Chondroitinase ABC promotes axonal regeneration of Clarke's neurons after spinal cord injury123
Abnormal development in transgenic mice expressing a campomelic dysplsia Sox9 mutation57
Evaluation of next generation sequencing software in mapping and assembly80
Activating ER-stress in differentiating osteocytes impairs maturation causing hyperostosis in mice95
Chondroitin sulphate proteoglycans produced by astrocytes modulate neuron adhesion and neurite outgrowth326
Investigating the role of FoxM1 in the maintenance of human embryonic stem cell pluripotency42
Pyrimidine nucleotide biosynthesis in adult angiostrongylus Cantonensis (Nematoda : Metastrongyloidea)218
A fast and accurate SNP detection algorithm for next-generation sequencing data115
Dimethylnitrosamine in salt fish in Hong Kong171
Signal involved in the switch to fate commitment of bone marrow-derived Schwann cells93
The role of CREB in Ras-induced expression of interleukin 8116
Inhibition of KAP1 enhances hypoxia-induced KSHV reactivation through RBP-J 84
Release of mitochondrial enzymes under the influence of ions, detergents, and sonication: comparisonbetween normal and hepatopathological states177
Zic2 synergistically enhances Hedgehog signalling through nuclear retention of Gli1 in cervical cancer cells145
Allogeneic mesenchymal stem cell transplantation into the intervertebral disc; effect of severity of degeneration and cell number on regeneration91
SOX9 governs differentiation stage-specific gene expression in growth plate chondrocytes via direct concomitant transactivation and repression170
Upregulation of chondroitin 6-sulfotransferase (C6ST) in rat sciatic nerves after crush-injury57
Heparan sulfates and heparanase at the mineralization front of the developing growth plate63
Experimentally induced unilateral tooth loss: Histochemical studies of the temporomandibular joint67
Long term expression of small interfering RNA targeting M2 gene induces effective inhibition of influenza A virus replication55
The mouse model and human disease51
A novel transcript isoform of STING that suppresses innate antiviral response76
Fracture healing in collagen type X deficient mice: abnormalities in structure and mechanical properties of the fracture callus63
The MLL-EEN fusion gene leads to maturation arrest and self-renewal of hematopoietic progenitors in ES cells and the development of myeloid leukemia in chimeric mice64
Nutritional zinc-deficiency and esophageal tumorigenesis in the rat: a study with n-nitrosobenzylmethylamine224
UHRF1 in Basal Cell Carcinoma26
Single nucleotide polymorphisms of complement component 5 and periodontitis102
Three genes in the aggrecan degradation pathway act synergistically to predispose to degenerative disc disease71
Chondrocyte antigen expression, immune response and susceptibility to arthritis80
Activation of TORC1 transcriptional coactivator through MEKK1-induced phosphorylation124
Role of matrix remodeling in endochondral bone formation52
The α2(XI) collagen gene lies within 8 kb of Pb in the proximal portion of the murine major histocompatibility complex77
Contribution of gain-of-function mutations in R1T1 to the pathogenesis of Noonan syndrome: a report of 3 new Chinese patients in Hong Kong117
Interaction of Hoxb3 and Hoxb1 in hindbrain patterning revealed by ectopic expression of Hoxb3 in rhombomere 469
Hoxb5 trans-activates Sox9 and regulates trunk neural crest cell development113
Genome-wide association study of adolescent idiopathic scoliosis in southern China84
Protective effects of salvianolic acid B, astragaloside IV, and DT on endothelial cells against damage induced by H2O277
EATdb: a database of human enhancers and their putative targets64
The identification of sequence elements that mediate stabilization of the CHOP/Gadd153 mRNA by N-(4-hydroxyphenyl)retinamide (4HPR/fenretinide)68
MGAS: a powerful tool for multivariate gene-based genome-wide association analysis87
Helicases as antiviral drug targets.114
A multi PDZ-domain protein Pdzd2 contributes to functional expression of sensory neuron-specific sodium channel NaV1.8125
Role of IHH signaling in the progression of digit joint formation85
YY1 controls Igκ repertoire and B-cell development, and localizes with condensin on the Igκ locus120
BMI-1 negatively regulates JAK-STAT signaling in leukemia124
Extracellular matrix and the stem cell niche in the regenerating planarian76
Multidisciplinary disc research50
An analysis of the functional significance of the 3'-untranslated region of CHOP/Gadd153 messenger RNA244
Collagen microspheres: a three-dimensional culture system for notochordal cells97
Inflammatory fibroid polyps of gastro-intestinal tract73
Functions of epidermal growth factor revealed by analysis of transgenic mice57
Involvement of PDZD2 in The Regulation of Pancreatic Beta Cell Development and Function61
NF90 Exerts Antiviral Activity through Regulation of PKR Phosphorylation and Stress Granules in Infected Cells106
Disc cell responses to the local environment of degenerated and non-degenerated intervertebral disc tissue38
Diverse factors are involved in maintaining X chromosome inactivation58
Mapping the locus for a novel cataract mouse mutant with microphthalmia and closed eyelid71
Understanding degenerative intervertebral disc disease through devlopmental genetics and genomics57
Disrupted growth plates and progressive deformities in osteogenesis imperfecta as a result of the substitution of glycine 585 by valine in the α2(I) chain of type I collagen77
Genetics121
Roles and Regulation of MIPT3 in Interferon Signaling57
Reanalysis of published DNA sequence amplified from cretaceous dinosaur egg fossil.84
An IFN-a/b receptor 1 promoter variant and hepatitis B virus synergistically increase the susceptibility to chronic hepatitis B72
Loss of yeast peroxiredoxin Tsa1p induces genome instability through activation of the DNA damage checkpoint and elevation of dNTP levels118
Characterization of newly synthesized proteoglycans isolated form renal proximal tubular epithelial cells in culture48
Semaphorin 3A and chondroitin sulfate proteoglycan networks of perineuronal nets regulate developing central vestibular circuitry58
Accelerated ageing in mice deficient in Zmpste24 protease is linked to p53 signalling activation301
The Role of Matrix Turnover on Differentiation of Intervertebral Disk Cells55
Functional and sequence analysis of human neuroglobin gene promoter region147
BAF250a is required for secondary heart field development71
Antiviral effect of DNA aptamers binding H5N1 virus nucleoprotein82
The anti-proliferative effects of sPDZD2 on prostate and non-prostate cancer cells76
The molecular basis of Indian hedgehog mutations in digit patterning60
Genetic study of HLA alleles with Alzheimer's disease135
Chemical modification of hemoglobin in intact whole cells: Morphological studies by scanning electron microscope64
The restrictive role of chondroitin sulfate moieties on the migration of cranial motor neurons in rat hindbrain development50
Activating ER-stress in differentiating osteocytes impairs maturation causing hyperostosis in mice82
wKGGSeq: A Comprehensive Strategy-Based and Disease-Targeted Online Framework to Facilitate Exome Sequencing Studies of Inherited Disorders114
Resveratrol Rescues SIRT1-Dependent Adult Stem Cell Decline and Alleviates Progeroid Features in Laminopathy-Based Progeria162
Significance of ligamentum flavum hypertrophy in developmental spinal stenosis34
Identification and in vitro affinity maturation of HIV-1 envelope glycoprotein-specific early intermediate B cells isolated from immortalized human naïve B cell library211
The role of Suppressed of Fused in neural stem cell proliferation41
A mouse femoral external fixation model for the study of fracture repair48
Mouse model with impaired matrix degradation at the chondro-osseous junction200
Hox Expression Profile and its Epigenetic Regulation during Chondrogenesis47
The influence of dietary vitamin A-deficiency on the metabolism of N-nitrosodimethylamine in the rat175
HTLV-I Tax self-association in optimal trans-activation function71
Periodontitis: A Common Oral Disease the Genetic Susceptibility169
Fast microfluidic temperature control for high resolution live cell imaging92
Targeted disruption of the mouse type X collagen gene reveals a role in bone formation59
Properties and potential applications of enteric neural crest stem cells from mouse embryonic gut68
A γA-crystallin mouse mutant Secc with small eye, cataract and closed eyelid91
Inhibition of the SARS coronavirus by Bismuth compounds64
In vivo study of asporin, a genetic risk factor for osteoarthritis and degenerative disc disease65
Improving the environment for axonal growth with use of recombinant chondroitinase ABC44
Heparan sulphates upregulate regeneration of transected sciatic nerves of adult guinea-pigs111
A base substitution at a splice site in the COL3A1 gene causes exon skipping and generates abnormal type III procollagen in a patient with Ehlers-Danlos syndrome type IV94
Kinesin-1 affects chondrocytes adhesion to extracellular matrix and motility47
Protein and gene expression profiles of the intervertebral disc: in health and disease68
Sox10 affects enteric neural crest cells migration in a Sox10NGFP/+ mutant60
Association study of PHOX2B as a candidate gene for Hirschsprung's disease122
The up-regulation of GADD153 expression in human epithelial tumor cells treated with N-(4-hydroxyphenyl)retinamide (4HPR)54
Trinations aging symposium125
Increased high sensitivity C reactive protein concentrations and increased arterial stiffness in children with a history of Kawasaki disease90
Astrocytic proteoglycans regulate neuronal adhesion and growth51
Cytodifferentiation agent-induced changes in production of sulfated proteoglycans in human colon carcinoma cells54
Hoxb3 deficiency impairs B lymphopoiesis and erythropoiesis in mouse bone marrow66
Toward exploring pluripotency landscape through light-induced tuning of Oct4 expression51
Changes in collagen stability and folding in lethal perinatal osteogenesis imperfecta. The effect of α1(I)-chain glycine-to-arginine substitutions158
The HBS1L-MYB intergenic region on chromosome 6q23 is a quantitative trait locus controlling fetal haemoglobin level in carriers of β-thalassaemia99
MERS coronavirus induces apoptosis in kidney and lung by upregulating Smad7 and FGF2255
Latent membrane protein 1 interacts with the proliferation and apoptotic pathways in epithelial cells70
Heparanase activity facilitates syndecan-1 shedding in airway inflammation78
Kif5b may play a role in impairing mouse memory : a behaviour and cellular study192
The roles of Irx3 and Irx5 genes in mammalian inner ear development60
MAD2-induced sensitization to vincristine is associated with mitotic arrest and Raf/Bcl-2 phosphorylation in nasopharyngeal carcinoma cells112
A small molecule inhibitor of Endoplasmic Reticulum Oxidation 1 (ERO1) with selectively reversible thiol reactivity66
The role of SoxE transcription factors in melanoma development122
MEKK1 phosphorylation of TORC 1 transcriptional coactivator61
New plasma surface-treated memory alloys: Towards a new generation of "smart" orthopaedic materials101
Role of fibrogenesis in control of disc degeneration70
Study of aptamer selection methodologies for developing piezoelectric quartz crystal biosensors to detect microalbuminaria, malaria and SARS biomarkers61
VCY2 protein interacts with the HECT domain of ubiquitin-protein ligase E3A115
Casein kinase 1delta functions at the centrosome and Golgi to promote ciliogenesis1343
Neuronal plasticity of otolith-related vestibular system109
N-(4-hydrxophenyl)retinamide induces up-regulation of GADD153 in a nasopharyngeal carcinoma cell line100
Chitosan conduits seeded with bone marrow stromal cell-derived schwann cells enhance regeneration of rat sciatic nerve75
Functional significance of the 3'-UTR in the mRNA of the stress- inducible protein CHOP/Gadd15323
Indian Hedgehog gene in endochondral bone formation61
Identification of a single genotype of hepatitis G virus by comparison of one complete genome from a healthy carrier with eight from patients with hepatitis96
Identification of a genetic modifier of CHD in Type IIA procollagen deficient mutant mice suggests a dynamic regulatory system in cardiac development66
Fibroblast growth factor receptor 1 (FGFR1) regulates terminal differentiation of hypertrophic chondrocytes52
Epigenetic inactivation of the miR-124-1 in haematological malignancies130
Engineering tumor targeting salmonella84
Mutation of conserved aspartates affects maturation of both aspartate mutant and endogenous presenilin 1 and presenilin 2 complexes111
Interleukin-1 beta (IL-1β) and osteoprotegrin (OPG) gene polymorphisms are associated with knee osteoarthritis in Chinese43
Bone fracture healing in laminopathy-based premature aging177
Influence of Fcγ RIIA and MBL polymorphisms on severe acute respiratory syndrome76
Analysis of Mll-Een Fusion Gene in Mouse Leukemic Model73
An examination of homeodomains and their binding sites189
Sox2 signaling in prosensory domain specification and subsequent hair cell differentiation in the developing cochlea79
Assessment of systemic inflammation in osteoarthritis patients by testing fatty-acid-binding protein 4 and adiponectin in plasma91
Kinetics and assay of ornithine transcarbamylase178
Chondroitin sulfate moieties expressed by migrating motor neurons in explant cultures of the rat hindbrain54
Tertiary structure prediction of SARS coronavirus helicase129
Abnormal diffusion tensor in nonsymptomatic familial amyotrophic lateral sclerosis with a causative superoxide dismutase 1 mutation221
Specific inhibition of protein disulphide reductase activity of a 60kda rat liver protein by adenine nucleotides48
Evaluation of serum clusterin as a surveillance tool for human hepatocellular carcinoma with hepatitis B virus related cirrhosis114
WTO TRIPS and its effect on the supply and development of medicines in China82
Aptamers against P. falciparum histidine rich protein 2 as a new approach to malaria diagnosis51
Mutations in IHH, encoding Indian hedgehog, cause brachydactyly type A-11239
Effects of fluoxetine on the restoration of plasticity in young adult vestibular nucleus56
A comparative study of two recombinant human glucose-6-phosphate dehydrogenase (G6PD) deficient variants with the normal enzyme191
Suppressor of fused (Su(fu)) functions upstream of notch pathway and plays domain specific function in orchestrating the maintenance and differentiation of hindbrain neural progenitor pools58
Inhibition of the replication of Sindbis virus XJ-160 by RNAi.56
Activation of TORCI transcriptional coactivator through MEKKI-induced phosphorylation and ubiquitination49
Differential fuctions of cyclooxygenase 1 and 2 in bone repair66
Insights into the function of SOX9 and campomelic dysplasia58
Generation of induced pluripotent stem (iPS) cells from bone-forming cells80
Precursor microRNA-programmed silencing complex assembly pathways in mammals.78
A structural mutation of the collagen α1(I)CB7 peptide in lethal perinatal osteogenesis imperfecta86
A study of fructose-1, 6-diphosphatase: some properties including ascorbate inhibition.193
Intervertebral disc regeneration by use of autologous mesenchymal stem cells, an experimental model in rabbits56
Roles of yeast peroxiredoxins in cellular defense against DNA damage41
Study of sPDZD2 function using in vitro and in vivo approaches226
A vagal neural crest specific enhancer for establishing transgenic mouse models65
Diagnosing malaria using DNA aptamers against P. falciparum LDH27
Carbon plasma immersion ion implantation of nickel-titanium shape memory alloys144
MicroRNA: master controllers of intracellular signaling pathways98
Combinatorial strategies towards spinal cord repair: enhancement of the Schwann cell bridge and modification of the graft-host interface59
Modulation of innate antiviral immunity by influenza virus NS1 protein46
Serum metabolomic biomarkers and lumbar disc degeneration51
Chondroitinases ABC I and II from Proteus Vulgaris for Therapuetic Use: Cloning and Characterization80
The roles of cyclin-dependent kinase 5 in dendtrite and synapse development53
Yeast TRAMP complex facilitates pre-mRNA splicing68
Signal transduction in the cardiac k-receptor98
Using antisense oligonucleotide in whole embryo culture to study gene interactions during mouse gastrulation190
The autocrine human secreted PDZ domain-containing protein 2 (sPDZD2) induces senescence or quiescence of prostate, breast and liver cancer cells via transcriptional activation of p5396
Functional Analysis of the Mouse Isthmin Gene Encoding a Novel Secreted Protein69
Nucleic acid aptamers against Plasmodium lactate dehydrogenase for malaria diagnosis - discovery, characterization, structure and application1232
Tracking down the migration of mouse neural crest cells90
Genomic Instability in Laminopathy-based Premature Aging103
Differential inhibitory activities and stabilisation of DNA aptamers against the SARS coronavirus helicase.107
Use of mesenchymal stem cells for intervertebral disc regeneration: A rabbit model54
Biochemical consequences of sedlin mutations that cause spondyloepiphyseal dysplasia tarda130
Spatiotemporal relationship between chondroitin sulfates and chondroitin 6-sulfotransferase in the neuroepithelium during mouse hindbrain development.63
Migration of mesenchymal stem cells to injured spinal cord through interaction of SDF-1/CXCR459
LRRK2 R1441G mice are more liable to dopamine depletion and locomotor inactivity116
Free-flow electrophoretic separation of isolated matrix vesicles of rabbit epiphyseal growthplate cartilage54
Effects of morphine and adrenal hormones on glucose uptake of the isolated rat diaphragm in presence of varying magnesium ionconcentration183
Prostate Cancer Growth Modulation By sPDZD277
Genetic polymorphism studies in periodontitis and Fcγ receptors81
The development of therapeutic DNA aptamers against various E3 ubiquitin ligase WWP1 truncations57
A novel transcript isoform of STING that sequesters cGAMP and dominantly inhibits innate nucleic acid sensing81
The association of disc degeneration based on magnetic resonance imaging and the presence of low back pain65
Bridge: A novel transactivating protein expressed in pancreatic beta cells interacts with E12/E47 proteins62
SELEX in silico81
Derivation of Schwann cell from mammalian skin for use in axonal degeneration68
Functional analysis of the Drosophila twist promoter reveals a dorsal-binding ventral activator region93
The functional crosstalk between MT1-MMP and ADAMs31
GWASdb: a database for human genetic variants identified by genome-wide association studies30
Single nucleotide polymorphisms of Fc-gamma receptor genes and periodontitis78
Low basal transcription of genes for tissue-specific collagens by fibroblasts and lymphoblastoid cells: Application to the characterization of a glycine 997 to serine substitution in α1(II) collagen chains of a patient with spondyloepiphyseal dysplasia75
Correlated evolution of transcription factors and their binding sites162
Unraveling the role of type X collagen during fracture repair55
The severe acute respiratory syndrome (SARS) coronavirus NTPasefhelicase belongs to a distinct class of 5′ to 3′ viral helicases177
Bone marrow-derived Schwann cells achieve fate commitment - a prerequisite for remyelination therapy150
Roles of a novel splice variant of human IFI16 in innate immune response51
Tailored selection of nucleic acid aptamers against sclerostin and aggrecanase for skeletal disease therapeutics48
Influence of nicotine on the biological activity of rabbit osteoblasts109
Nanomechanical study of vimentin intermediate filament63
Next generation sequencing has lower sequence coverage and poorer SNP-detection capability in the regulatory regions78
Direct interaction of microtubule- and actin-based transport motors72
Modification of the RpoS network with an artificial small RNA.54
Formation of novel pattern by programming cell motility75
The role of matrix remodeling in endochondral ossification43
Recurrent substitutions of arginine 789 by cysteine in pro-α1 (II) collagen chains produce spondyloepiphyseal dysplasia congenita62
A functional single-nucleotide polymorphism in the promoter of the gene encoding interleukin 6 is associated with susceptibility to tuberculosis119
The interaction of flavivirus M protein with light chain Tctex-1 of human dynein plays a role in late stages of virus replication92
Clinical phenotypes of a large Chinese multigenerational kindred with autosomal dominant familial ALS due to Ile149Thr SOD1 gene mutation135
The roles of Irx3 and Irx5 genes in mammalian inner ear development231
Elucidation of ganglioside binding domain in the B-subunit of cholera toxin207
Cells in the endplate cartilage contribute to the inner annulus fibrosus in the intervertebral disc131
Regulation of the transferrin receptor expression during phorbol ester-induced differentiation in HK-60 cells54
Regulation of gene expression in hypertrophic chondrocytes56
Towards understanding genetic and molecular etiology of campomelic dysplasia41
Studies of gene regulation using microarray data147
PTPN21 exerts pro-neuronal survival and neuritic elongation via ErbB4/NRG3 signaling90
Negative regulation of RIG-1 mediated IRF3 activation by TAK161
CRTC1 transcriptional coactivator is required for hepatitis B virus gene expression and replication61
The relationship of ligamentum flavum changes and developmental spinal stenosis33
Three novel mutation in exon 3 suggest a possible hot-spot in the RET proto-oncogene for Hirschsprung's disease93
EEN encodes for a member of a new family of proteins containing an Src homology 3 domain and is the third gene located on chromosome 19p13 that fuses to MLL in human leukemia134
Divergent routes for derivation of alternative glial cell fate from bone marrow stromal cells of adult rats for remyelination56
A mouse model for hearing and balance defects in campomelic dysplasia87
Study of abnormal inner ear development in Waardenburg-Shah syndrome using a Sox10-GEP mutant mouse model239
Discovering gene function and disease mechanisms through forward and reverse developmental genetics42
Cellular stress pathways in cartilage biology and disease254
SiRNA and shRNA screens advance key understanding of host factors required for HIV-1 replication115
Unfolded protein response leading to cataractogenesis in a microphthalmia cataract mouse mutant49
Suppression of nickel release in nickeltitanium alloys by plasma immersion ion implantation surface treatment: towards a new generation of "smart" orthopaedic implants78
Mechanism of regulatory target selection by the SOX high-mobility-group domain proteins as revealed by comparison of SOX1/2/3 and SOX987
Power of transmission/disequilibrium tests in admixed populations130
Overexpression of the winged helix transcription factor WIN in HeLa cells alters cell-cycle kinetics48
In vitro and in vivo studies of perineuronal glycosaminoglycans in synaptic functions59
Bacterial scavengase p20 is structurally and functionally related to peroxiredoxins95
Genomic instability and accelerated cellular senescence inlaminopathy-based premature242
Descendents of LGR5-expressing interzone cells are localized to the superficial layer of the articular cartilage86
Shape transformation of the nuclear envelope during cell division43
Overexpression of epidermal growth factor induced hypospermatogenesis in transgenic mice66
Functional roles of heparanase in endochondral ossification199
Cell cycle-related kinase supports ovarian carcinoma cell proliferation via regulation of cyclin D1 and is a predictor of outcome in patients with ovarian carcinoma115
Roles of perineuronal matrix in developmental plasticity of the central vestibular system68
Deletion of 24 amino acids from the Pro-α1(I) chain of type I procollagen in a patient with the Ehlers-Danlos syndrome type VII50
Postnatal refinement of gravity-related spatial coding to the central vestibular circuitry97
Heparan sulphate moieties of syndecan-1 bind neutrophil elastase and modulate access of anti-elastase: Implications in the pathogenesis of bronchiectasis50
Transcriptional genomics associates FOX transcription factors with human heart failure118
DNA aptamers for diagnostic applications – structural insight into discriminatory recognition of malaria diagnostic targets21
Overexpression of AIB1 negatively affects survival of surgically resected non-small-cell lung cancer patients106
Requirement of N-linked glycosylation for optimal proteolytic activation of liver-enriched transcription factor CREB-H274
Different effects of chondroitin and heparan sulphates on the regenerative efficacy of transected sciatic nerves of adult guinea pigs45
DDGni: dynamic delay gene-network inference from high-temporal data using gapped local alignment207
Generalizations of Markov model to characterize biological sequences69
Selection, validation and delivery of DNA aptamers against infectious disease targets90
Indian hedgehog mutations causing brachydactyly type A1 impair Hedgehog signal transduction at multiple levels231
Intervertebral disc regeneration by use of autologous mesenchymal stem cells, an experimental model in rabbits50
Chitosan nanofiber composed nerve conduit for directing axonal growth63
Vaccinia virus hemagglutinin. A novel member of the immunoglobulin superfamily105
Molecular genetic dissection of mouse unconventional myosin-VA: Head region mutations59
Chondroitin sulfate proteoglycans (CSPG) produced by schwann cells in astrocyte-schwann cell cocultures limit neurite extension and crossing of cellular boundaries61
Cyp26b1 mediates differential regulation of RA signaling in neural progenitor populations along the anteriorposterior axis of the adult spinal cord58
sPDZD2: a novel negative modulator of hedgehog signaling70
Deleted in Liver Cancer 2, DLC2, suppresses cell transformation via inhibition of rhoa activity81
Protection of cigarette smoke–induced up-regulation of neutrophil elastase by Chinese green tea in rat lung75
Linkage analysis on familial early-onset degenerative disc disease110
The genetic polymorphisms in sex steroid metabolic pathway and risk for sporadic Alzheimer's disease55
The expression of tissue inhibitor of metalloproteinase (TIMP) during the early stages of healing in both endochondral and intramembranous bone grafts58
Copy-number variations involving the IHH locus are associated with syndactyly and craniosynostosis135
Eya1-Six1 Interaction Is Sufficient to Induce Hair Cell Fate in the Cochlea by Activating Atoh1 Expression in Cooperation with Sox295
Interactions of Hox genes during craniofacial development78
Priming with rAAV encoding RBD of SARS-CoV S protein and boosting with RBD-specific peptides for T cell epitopes elevated humoral and cellular immune responses against SARS-CoV infection106
Single-stranded oligonucleotide-medicated gene repair in mammalian cells has a mechanism distinct from homologous recombination repair67
Insights into the molecular basis of the variants: G6PD mahidol and G6PD plymouth190
The kinetics of invertin action27
Methods in Microbiology (Chapter 2)53
Inositol lipids in cardiomyocytes: relationship to k-agonist signal transduction67
Functional roles for Irx3 and Irx5 in osteoblast differentiation43
Prevalence of intervertebral disc degeneration in Hong Kong-a magnetic resonance imaging study of 977 volunteers102
ChIP-Array 2: integrating multiple omics data to construct gene regulatory networks84
NRProF: Neural response based protein function prediction algorithm73
Diadenosine polyphosphate analogue modulates signal transduction in hippocampal slices59
Differential involvement of perineuronal net components in functional modifications of vestibular nuclear neurons in the rat57
Identification of master regulators in non-small-cell lung carcinoma22
β-catenin in reverse action72
Conserved transcription factor binding sites of cancer markers derived from primary lung adenocarcinoma microarrays118
Transcriptional Control of Sensory Versus Non Sensory Progenitor Specification in the Inner Ear52
Aberrant KLF4 expression and BMP signaling cause proliferation defect in PTC1-/- neural crest cells110
Elevated TAK1 augments tumor growth and metastatic capacities of ovarian cancer cells through activation of NF-κB signaling97
Protein and gene expression profiles of the intervertebral disc: in health and disease54
In vivo plasticity in terminal differentiation of hypertrophic chondrocytes induced by ER stress.58
Calcium oxalate crystallizing properties of polyanions elaborated by cultured renal proximal tubular cells110
Degradation of lung matrix proteoglycans in bronchiectasis69
An SNP selection strategy identified IL-22 associating with susceptibility to tuberculosis in Chinese112
Coexpression of GABA BR1 and GABA BR2 receptor subunits in the rat vestibular nucleus89
Identification of multiple isoforms of DLC2, a novel tumor suppressor gene, and their functional characterization in hepatocellular carcinoma61
In vivo analysis of the transactivation specificity of group E SOX proteins57
Association of chromosome 6p multiple regions with nasopharyngeal carcinoma and gene expression changes in cancer tissue79
Neutrophil elastase changes its binding partner following neutrophil degranulation in airway inflammation54
Post-translational regulation of Sox9 in neural crest delamination86
Studying the role of Sox10 in enteric neural crest cell migration with Sox10NGFP mouse mutant223
Computational discovery of cis-regulatory modules in human genome by genome comparison272
Prolactin profile in a cohort of Chinese systemic lupus erythematosus patients86
Use of sulfated maltoheptaose to lower neutrophilic inflammation in a rat model of cigarette smoke-induced chronic obstructive pulmonary disease79
Insights into the molecular pathogenesis of Campomelic dysplasia caused by mutations in SOX957
ER-stress signaling in the pathogenesis of Schmid metaphyseal chondrodysplasia70
Serological profiling of a Candida albicans protein microarray reveals permanent host-pathogen interplay and stage-specific responses during candidemia64
Genotype-phenotype relationships in the regulation of skeletal formation and growth40
Inhibition of melanoma growth by subcutaneous administration of hTERTC27 viral cocktail in C57BL/6 mice.92
Investigating the function of SOX9 in development43
The role of Sox2 and Sox18 in mouse hair development43
Mouse model with impaired collagen X degradation at the chondro-osseous junction53
Extracellular matrix and stem cell niche in the regenerating planarian68
Sequential expression of Lgr5 and Col22a1 in developing synovial joints marks the progressive differentiation of progenitor cells to articular chondrocytes88
UHRF1 regulated hair follicle stem cells self-renewal40
Molecular consequences of Indian hedgehog mutations in chick neural tube57
Genetic variation in the Col9A2 gene and its association to intervertebral disc abnormalities in Southern Chinese97
Different cis-regulatory DNA elements mediate developmental stage- and tissue-specific expression of the human COL2A1 gene in transgenic mice108
Derivation of oligodendrocyte precursor cells from bone marrow stromal cells for remyelination therapy59
A hypothesis for the function of collagen X60
Prevalence and pattern of lumbar magnetic resonance imaging changes in a population study of one thousand forty-three individuals320
Arthritis susceptibility in mice expressing human type II collagen in cartilage80
Parallel, Beneficial Genome Reduction During Adaptation of Experimental Populations24
Hyaluronan is identified in urine of renal stone formers59
PTHGRN: unraveling post-translational hierarchical gene regulatory networks using PPI, ChIP-seq and gene expression data153
Cdk5: Mediator of neuronal death and survival1351
Directed Differentiation of Human Induced Pluripotent Stem Cells to Sensory Neurons by Combined Small Molecule Inhibitors57
NdPASA: A pairwise sequence alignment server for distantly related proteins99
Abnormal enteric ganglia development in a Sox10 mouse mutant generated by gene targeting99
The hypothalamo-neurohypophsial secretinergic pathway in regulating body water homeostasis71
Aptamer-mediated Inhibition of Mycobacterium tuberculosis Polyphosphate Kinase 2204
Molecular delineation of the sprague-dawley rat b-globin gene cluster64
The Overexpression of Bcl-2 Antagonizes the Proapoptotic Function of the Kappa-Opioid Receptor90
The effect of lack of collagen X on fracture healing70
The regulation of FGF signaling by MT1-MMP in calvarial osteogenesis34
CREB - A real culprit in oncogenesis79
Chinese patients with rasopathies: Detection of 29 known and novel variants using next-generation sequencing (NGS)70
Inferring Gene Regulatory Networks from Integrative Omics Data via LASSO-type regularization methods81
Novel aspects of corneal angiogenic and lymphangiogenic privilege84
TNF-a in bronchial secretions of patients with bronchiectasis stimulates neutrophil-mediated degradation of lung proteoglycans57
iCartiGD: The Integrated Cartilage Gene Database125
Differential protein profiling of stressed chondrocytes and skeletal dysplasia disease66
Embryonic development of the ganglion plexuses and the concentric layer structure of human gut: A topographical study139
A study of tissue plasminogen activator forms from human small intestine70
Glycosaminoglycan composition of nervous tissues of guinea pig: implications for regenerative capacity51
Differential expression of NMDA and AMPA/KA receptor subunits in the inferior olive of postnatal rats116
Nutritional and insulin regulation of fatty acid synthetase and leptin gene expression through ADD1/SREBP1149
Study of polymorphisms of vitamin D receptor gene in lumbar disc degeneration in Chinese54
The dual effect of urinary macromolecules on the crystallization of calcium oxalate endogenous in urine73
HOXB3 Mutation Generated By Gene Targeting Leads to Plasmacytoma60
A novel 3-dimensional culture system for mouse embryonic stem cells65
Effect of lithium and myo-inositol on the time courses of changes in inositol trisphosphate and free calcium concentrations in K opioid agonist-stimulated rat ventricular myocytes (Abstract)49
Putative cellular receptor for secreted PDZ domain-containing protein 2 (sPDZD2) in cancer cells71
Bridge-1 utilizes a PDZ-like domain to coactivate E2A-mediated insulin gene transcription84
Expression of the a1(II) collagen gene during early mouse embryogenesis59
Studies on alkaline phosphatase and its relationship to phosphorylation of matrix vesicle components219
Genetic Basis of Intervertebral Disc Degeneration122
Molecular pathogenesis of hepatitis C virus-associated hepatocellular carcinoma102
UHRF1 double tudor domain and the adjacent PHD finger act together to recognize K9me3-containing histone H3 tail95
Integration of pathways mediating chondrocyte adaptation to ER stress in VIVO56
The role of Sox genes in inner ear development30
Prognostic impact of H3K27me3 expression on locoregional progression after chemoradiotherapy in esophageal squamous cell carcinoma92
Characterization of cre expression in BAC-Pcp2-IRES-Cre transgenic mice173
Evidence for a new gene associated with Hirschsprung's disease: the PHOX2B gene66
Urinary glycosaminoglycans and their influence on calcium oxalate crystalization in urine ultrafiltrate59
An EBV microRNA targets DICE1 tumor suppressor gene51
Developing a new approach to degenerative disc disease therapy: DNA aptamers to inhibit aggrecanases63
Spatial distribution pattern of murine CD34 mRNA+ cells in hematopoietic and lymphoid organs179
Overexpression of FOXG1 contributes to TGF-β resistance through inhibition of p21 WAF1/CIP1 expression in ovarian cancer116
Activation of SIRT1 by resveratrol requires lamin A93
The linear and rotational motions of the fission yeast nucleus are governed by the stochastic dynamics of spatially distributed microtubules75
In vitro selection of DNA and RNA aptamers against sclerostin67
Protein kinase TTK interacts and co-localizes with CENP-E to the kinetochore of human cells104
BDNF regulates plasticity in spatial coding113
An essential role for type IIA procollagen in heart development47
The transcription factor WIN alters cell cycle kinetics through modulation of cyclin expression60
The functional crosstalk between MT1-MMP and ADAMs in craniofacial & vascular development145
Notch signaling in differentiation of bone marrow-derived Schwann cells55
Investigations into the feasibility of single-strandedoligonucleotide-mediated targeted gene repair in mammalian cells155
Generation of induced pluripotent stem (iPS) cells from bone-formating cells68
Prevalence, psychosocial and physical health correlates of psychotic disorders in Hong Kong: the Hong Kong Mental Health Morbidity Survey1037
Potent Paracrine Effects of human induced Pluripotent Stem Cell-derived Mesenchymal Stem Cells Attenuate Doxorubicin-induced Cardiomyopathy128
Molecular basis for increased bone formation in a mouse expressing mutant type X collagen45
Selection and delivery of aptamers against the SARS Coronavirus Helicase45
The role of hypoxia-inducible factor-1 in choroidal neovascularization54
SOX9 directly regulates the type-II collagen gene298
An Ideal Mouse Model for Ageing Research64
Using biomarker signature patterns for an mRNA molecular diagnostic of mouse embryonic stem cell differentiation state82
Defective adult muscle satellite cells in Zmpste24 deficient mice208
Sputum sol neutrophil elastase activity in bronchiectasis: Differential modulation by syndecan-189
Adeno-associated virus vector-mediated angiogenic inhibitors suppress lung tumor growth in mice67
C6ST expression in sciatic nerve explant culture of adult rats76
Fabrication of an osteochondral construct with an intact interface using rabbit mesenchymal stem cells (rMSCs) and collagen gel84
An Epstein-Barr virus-encoded microRNA targets PUMA to promote host cell survival131
UreE-Hpn/Hpnl interaction in H. pylori, and the role of cysteines in Hpn240
Early results of the effect of lack of collagen X on fracture healing53
Aligned chitosan nanofibers seeded with Schwann cells for construction of a nerve guidance channel112
Functional characterization of a novel RhoGAP protein Deleted in Liver Cancer 2 (DLC2)66
Identification and characterization of distal regulatory element of human NGB gene81
Molecular genetic dissection of mouse unconventional myosin-VA: Tail region mutations81
Molecular analysis of a novel winged helix protein, WIN. Expression pattern, DNA binding property, and alternative splicing within the DNA binding domain138
A novel mutation, D404N, in the connection subdomain of reverse transcriptase of HIV-1 CRF08_BC subtype confers cross-resistance to NNRTIs177
Sulfated maltoheptaose reduces neutrophilic airway inflammation in a smoking rat model of chronic obstructive pulmonary disease74
Genetics study in intervertebral disc degeneration.87
Role of ERO1-α-mediated stimulation of inositol 1,4,5-triphosphate receptor activity in endoplasmic reticulum stress-induced apoptosis73
Solution structures and dynamics of the sterile α Motif (SAM) domain of the deleted in liver cancer 2 (DLC2): a monomeric structure with membrane-binding properties74
In vitro and in vivo characterization of novel plasma treated nickel titanium shape memory alloy for orthopedic implantation125
'One Health' for the people of Hong Kong and the world55
Modifications in perineuronal nets within the rat vestibular nuclei during postnatal development and in injury53
Chondrocytes survive ER stress caused by unfolded proteins via re-programming72
Analysis of long-range chromatin interaction and how transcription factors are involved to regulate gene expression52
Molecular cloning of a gene coding for abundant transcript in red blood cells of the anemic rat.51
Human TRBP and PACT directly interact with each other and form a complex with Dicer to promote the production of small interfering RNA67
Perturbation of GABA synapses in vestibular nucleus during a postnatal critical period impacts on the establishment of spatial recognition63
The role of MT1-MMP in regulating lineage progression of chondrocytes62
A novel aptamer-mediated approach for degenerative disc disease therapy34
Duplication and divergence of SoxE function during chordate evolution52
Evaluation of the purity of recombinant proteins and detection of residual protein contaminants via N-terminal microsequencing and database searching.65
Molecular and developmental insights into the pathogenesis of the SOX9Y440X campomelic dysplasia mutation83
NKCC1 and KCC2 cotransporters are required in postnatal maturation of the vestibular system45
Characterization of the specificity of Cre expression in cerebellar Purkinje cells56
Removal of antagonistic spindle forces can rescue metaphase spindle length and reduce chromosome segregation defects137
The use of cells doubly labelled with [ 14C]inositol and [ 3H]inositol to search for a hormone-sensitive inositol lipid pool with atypically rapid metabolic turnover74
The role of autophagy in determining chondrocyte cell fates in response to ER stress73
Effect of severity of intervertebral disc injury on mesenchymal stem cell-based regeneration91
Identification and characterization of a novel transcript isoform of STING that suppresses innate immune response374
Angiogenesis and lung cancer: antiangiogenic agent and therapy99
Phenotype analysis of Pdss2 conditional knockout mouse191
Stem Cell decline and Aging32
Identification of candidate genes for bone mineral density variation in Southern Chinese by integrating computational gene prioritization,linkage and association approaches224
Collagen evolution99
Glycosaminoglycan composition of sciatic nerves of guinea pigs: effects of nerve crush53
HS/syndecan modulate proteolytic balance in airway inflammation61
E3 ubiquitin ligase WWP1 - an intracellar target for aptameric inhibition41
A centrosomal target of HTLV-I Tax on the road to genome instability55
Biochemical characterization of Gppa-ppx homologues from Mycobacterium tuberculosis82
Induction of threonine dehydratase in developing rat liver198
Translationally controlled tumor protein induces mitotic defects and chromosome missegregation in hepatocellular carcinoma development162
Specific inhibition of protein disulphide reductase activity of a 60kda rat liver protein by adenine nucleotides60
Developmental Origins of Osteoblasts in Endochondral Bone Formation54
Injury-associated changes in glycosaminoglycans and their effects on the regeneration of transected sciatic nerves of guinea pigs65
The interaction between EEN and Abi-1, two MLL fusion partners, and synaptojanin and dynamin: Implications for leukaemogenesis120
A fast and accurate SNP detection algorithm for next-generation sequencing data80
Sonic hedgehog (SHH) regulates the migration and differentiation of the enteric neural crest stem cells (NCSCs) in gastrointestinal tract86
Phosphorylation of matrix vesicle comonents - dependent on alkaline phosphatase69
Molecular and cellular consequences of Indian hedgehog mutations causing brachydactylies23
The complete genome and proteome of laribacter hongkongensis reveal potential mechanisms for adaptations to different temperatures and habitats137
Nek2A kinase regulates the localization of numatrin to centrosome in mitosis90
Human T-cell leukemia virus type I oncoprotein Tax targets the centrosome61
Characterization and mutational analysis of an exopolyphosphatase from Mycobacterium smegmatis78
Aberrant Kruppel-like factor 4 expression causes proliferation defect in Patched1-/- neural crest cells205
Derivation of oligodendrocyte precursors from bone marrow stromal cells for mylination therapy68
Sputum stimulation of human neutrophil degradation of lung proteoglycans72
Targeted genome editing of Epstein-Barr virus by CRISPR/Cas9 technology in human cells341
Derivation of human neural crest stem cells from human induced pluripotent stem cells59
Developmental expression of NMDA and AMPA receptor subunits in vestibular nuclear neurons that encode gravity-related horizontal orientations122
Analysis of multiple cardiac abnormalities of a knockout mouse mutant Hoxb3Hoxb3lacZ52
Three dimensional culture and chondrogenic differentiation of mouse embryonic stem cells60
Control of cranial motor neuron migration by divergent expression of chondroitin sulfotransferases in rat hindbrain development46
Towards myelin and functional recovery in the injured CNS: derivation of oligodendrocyte precursor cells from adult bone marrow stromal cells53
Regulation of glycogen phosphorylase in hypoxic cancer cells284
Utility of Epstein-Barr virus-encoded small RNA promoters for driving the expression of fusion transcripts harboring short hairpin RNAs94
Secretin, a known gastrointestinal peptide, is widely expressed during mouse embryonic development137
Determination of the functions of the putative metal-binding domain of the SCV helicase.91
Impaired G(s)α and adenylyl cyclase cause β-adrenoceptor desensitization in chronically hypoxic rat hearts90
Epigenetic inactivation of the miR-34a in hematological malignancies95
Balance of Power in Host-Virus Arms Races72
Mmb1p binds mitochondria to dynamic microtubules81
Resolving the debate about ontogeny of bone cells33
EM23, a natural sesquiterpene lactone, targets thioredoxin reductase to activate JNK and cell death pathways in human cervical cancer cells119
Molecular consequences of Indian hedgehog mutations causing brachydactylies67
Heparan sulphate moieties bind neutrophil elastase: implications in the pathogenesis of bronchiectasis189
Mesenchymal stem cells reduce intervertebral disc fibrosis and facilitate repair156
Creation of biological patterns controlled by synthetic genetic circuits13
A centrosomal target of human T-cell leukemia virus type I oncoprotein Tax63
Remembering ...50
Over-expression of mutant SOX10 in the vagal neural crest causes hypoganglionic colon development in transgenic mice78
Structural basis for discriminatory recognition of Plasmodium lactate dehydrogenase by a DNA aptamer117
Bone Pathology66
KIF5b interaction with NMDA receptor mediates NO production in neuron66
Conditional Ptc1 knockout in vagal neural crest cells causes a reduced proliferation of enteric nervous system progenitors and intestinal hypoganglionosis102
Alcanivorax dieselolei sp. nov., a novel alkane-degrading bacterium isolated from sea water and deep-sea sediment106
Inhibitory effect of Chinese green tea on cigarette smoke-induced up-regulation of airway neutrophil elastase and matrix metalloproteinase-12 via antioxidant activity117
Rare SNP rs12731181 in the miR-590-3p Target Site of the Prostaglandin F2α Receptor Gene Confers Risk for Essential Hypertension in the Han Chinese PopulationSignificance97
Understanding the contribution of Lgr5+ interzone progenitor cells in joint repair49
Chick Sox10, a transcription factor expressed in both early neural crest cells and central nervous system152
Identification and characterization of FTSJ2, a novel human nucleolar protein homologous to bacterial ribosomal RNA methyltransferase104
Neural crest development is regulated by the transcription factor Sox9268
Nitrated chondroitin sulfate proteoglycans in cerebrospinal fluid of patients with amyotrophic lateral sclerosis53
Peroxiredoxin-null yeast cells are hypersensitive to oxidative stress and are genomically unstable155
A non-synonymous single nucleotide polymorphism in IFNAR1 affects susceptibility to chronic hepatitis B virus infection113
Misfolding of collagen X chains harboring schmid metaphyseal chondrodysplasia mutations results in aberrant disulfide bond formation, intracellular retention, and activation of the unfolded protein response96
κ-Opioid receptor potentiates apoptosis via a phospholipase C pathway in the CNE2 human epithelial tumor cell line91
The mitogen-activated protein kinase pathway regulates the subcellularlocalization and function of FOXM1234
MT1-MMP in FGF Signaling51
B Cell Development Defect in ZMPSTE24-/-Mice92
PDSS2 requirements for cerebellar development and functions56
New plasma surface treated memory alloys: Towards a new generation of "smart" orthopaedic materials78
Cdk5: A multifaceted kinase in neurodegenerative diseases153
Surviving endoplasmic reticulum stress is coupled to altered chondrocyte differentiation and function.191
Effect of a non-hydrolyzable analog of diadenosine polyphosphates on NMDA-mediated currents in isolated pyramidal neurons of the rat hippocampus98
SOX9 binds DNA, activates transcription, and coexpresses with type II collagen during chondrogenesis in the mouse92
Efficient and seamless DNA recombineering using a thymidylate synthase A selection system in Escherichia coli90
Mapping heparanase expression in the spinal cord of adult rats129
Genome-wide identification of target genes repressed by the zinc finger transcription factor REST/NRSF in the HEK 293 cell line90
Abnormalities in fracture healing in the absence of collagen type X70
Functionally replicated bioimprint scaffold to support tenocytic differentiation of mesenchymal stem cells57
Autophagy in normal skeletal development and disease174
Role of endocannabinoid and GABAA receptor in modulating synaptic plasticity in the vestibular nucleus of postnatal rats49
Functional study of stem-cell-derived Schwann cells using an in-vitro dorsal root ganglia model81
Is there a role for the IHH gene in Hirschsprung's disease?116
Interaction of deleted in liver cancer 1 (DLC1) with tensin2 and its implications in tumor suppression81
PBL approach to teaching metabolism to B.Sc. Biochemistry students76
Communication in medical education: harnessing the power of the Internet76
NRProF: Neural Response Based Protein Function Prediction Algorithm25
Effect of MAD2 expression on chemosensitivity to DNA damaging agent cisplatin in nasopharyngeal carcinoma cells79
Nedocromil sodium in the management of chronic bronchial infection84
Mutation of the conserved N-terminal cysteine (Cys92) of human presenilin 1 causes increased Aβ42 secretion in mammalian cells but impaired Notch/lin-12 signalling in C. elegans71
The Irx3 and Irx5 genes in inner ear development79
The TRP2 allele of COL9A2 is an age-dependent risk factor for the development and severity of intervertebral disc degeneration172
Generation of induced pluripotent stem (iPS) cells from bone forming cells70
κ-opioid receptor agonist inhibits the cholera toxin-sensitive G protein in the heart90
Mutant Sox9 exerts context dependent gain-of-function impact in a campomelic dysplasia mouse model63
G6PD deficiency from lyonization after hematopoietic stem cell transplantation from female heterozygous donors131
Glycosaminoglycan composition in the regenerative environment of the sciatic nerve of adult hamsters53
Phenotypic and population differences in the association between CILP and lumbar disc disease133
Analysis of long-range chromatin interaction and how transcription factors are involved to regulate gene expression42
Abnormal enteric nervous system development in a Sox10-NGFP mouse mutant118
Study of nickel suppression and cyto-compatibility of plasma immersion ion implantation treated nickel titanium shape memory alloys62
Functional Genomics: Lessons learnt from manipulating the mouse genome41
Assessment of aligner and SNP caller for next generation sequencing and a fast and accurate SNP detection method107
Differential requirement of suppressor of fused (Su(fu)) in mammalian hedgehog signaling and neural development55
An essential role for β1 integrin mediated cell-matrix interactions in the development and maintenance of the nucleus pulposus98
The mouse Col2a-1 gene is highly conserved and is linked to Int-1 on Chromosome 1580
Hox homeobox genes and regionalisation of the nervous system114
Psr1p interacts with SUN/sad1p and EB1/mal3p to establish the bipolar spindle69
Solution structure of cytochrome b5 mutant (E44/48/56A/D60A) and its interaction with cytochrome c105
A method to generate recombinant Salmonella typhi Ty21a strains expressing multiple heterologous genes using an improved recombineering strategy139
Sequential establishment of stripe patterns in an expanding cell population291
Crystal-active and crystal-inhibitory components of urinary macromolecules99
Axonal APP interacts with BACE in anterograde transport-dependent manner78
DNA aptamers can discriminate between closely related aggrecanase drug targets for degenerative disc disease therapy53
Autophagy deregulation in neurodegenerative diseases - Recent advances and future perspectives109
Cryopreserved intervertebral disc with injected bone marrow-derived stromal cells: a feasibility study using organ culture93
MT1-MMP regulates FGF signaling in osteogenesis70
Role of adapter function in oncoprotein-mediated activation of NF-κB: Human T-cell leukemia virus type I Tax interacts directly with IκB kinase γ74
Scavengase p20: A novel family of bacterial antioxidant enzymes108
Study on the role of epidermal growth factor in chondrogenesis69
The inhibitory effects of siRNAS targeting the replicase or structural genes of the sars-associated coronavirus (SCOV) on viral replication70
The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease160
Defining the phenotype and molecular signatures of notochordal nucleus pulposus cells84
Influence of digits, ectoderm, and retinoic acid on chondrogenesis by mouse interdigital mesoderm in culture80
Culture of chondrocytes of hereditary multiple exostosis in vitro81
Resveratrol activates SIRT1 in a Lamin A-dependent manner73
Towards myelin repair in the CNS: generation of oligodendrocyte precursor ce lls from adult bone marrow stromal cells47
The influence of progenitor cells in intervertebral disc degeneration and regeneration46
Abnormal chondrocyte differentiation in transgenic mice expressing a Schmid metaphyseal chondrodysplasia Col10a1 mutation84
Loss of MKP3 mediated by oxidative stress enhances tumorigenicity and chemoresistance of ovarian cancer cells138
Mapping of genetic modifier of congenital heart defects in type IIA procollagen deficient mice54
Procollagen IIA facilitates BMP signaling in heart development58
Expression of extracellular matrix genes during skeletogenesis: the role of type II collagen183
Chondroitin sulfate moieties that are upregulated in Schwann cell-astrocyte encounters81
TRAPPC9 mediates the interaction between p150 glued and COPII vesicles at the target membrane104
Active transcription promotes single-stranded oligonucleotide mediated gene repair135
Experimental therapy for solid tumors by in situ retro viral mediated gene transfer74
Heparan sulfates upregulate regeneration of transected sciatic nerves of adult guinea pigs196
Molecular developmental genetics of the inner ear mutant, yellow submarine (Ysb)212
Emerging role of perineural chondroitin sulfates and semaphorin 3A in maturation of the central vestibular circuitry36
The Role of Chondroitin Sulfate Moieties on Cranial Motor Neuron Migration in the Developing Hindbrain of Rates50
Study of enhanced corrosion resistance and biocompatibility by plasma implantation of nickel-titanium alloys: An in-vitro and surface chemical analysis54
Kinesin-1 is involved in chondrocytes adhesion to extracellular matrix and motility57
MT1-MMP in regulating growth factor signalling and development24
Gene structure and expression of human pro-alpha2(XI) collagen (col11A2) gene186
In vivo and in vitro studies on the regulation of C-KI-RAS expression in liver154
Mouse model with impaired collagen X degradation at the chondro-osseus junction49
Mechanistic insight into point mutations in sedlin that result in spondyloepiphyseal dysplasia tarda61
Transcriptional regulation of mitotic checkpoint gene MAD1by p5351
Phosphorylation of Sox9 is required for neural crest delamination and is regulated downstream of BMP and canonical Wnt signaling154
SNP rs11190870 near LBX1 is associated with adolescent idiopathic scoliosis in southern Chinese138
Differential and overlapping expression pattern of SOX2 and SOX9 in inner ear development128
Nucleic acid aptamers for sensing applications: aptamers for diagnosing malaria51
Krüppel-like factor 4 (KLF4) in neuroblastoma69
A mechanistic study of lambdaphage-mediated recombination in E. coli348
The regulation of motor neuron migration by differential expression of chondroitin sulfotransferase in rat hindbrain development52
Epitope specificity of antibodies to type II collagen in rheumatoid arthritis and systemic lupus erythematosus101
Secreted PDZ domain-containing protein 2 (sPDZD2) exerts insulinotropic effects on INS-1E cells via a protein kinase A-dependent mechanism194
Molecular control of osteo-chondroprogenitors formation213
Negative regulation of type-I interferon production by MIP-T3268
Understanding how polymorphisms in cerberus-like result in low bone mineral density64
Chinese green tea protects cigarette smoke-induced up-regulation of neutrophil elastase in rat lung84
Loss of yeast peroxiredoxin TSA1 induces genome instability through constitutive activation of DNA damage checkpoint and elevation of cellular dNTP levels62
Expression patterns of housekeeping genes in cancer191
Acquisition of glutamate receptors in central vestibular synapses is crucial for developmental recognition of spatial orientation96
Regulation of SIRT6 activities by the lamins33
Mesenchymal stem cells based osteochondral tissue engineering56
A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer208
Aptamer-based inhibitor of sclerostin for Osteoporosis Therapy81
The establishment and interpretation of transcription factor gradients in the Drosophila embryo88
Osteogenic differentiation of alginate microencapsulated mesenchymal stem cells for bone formation in osteoporosis spine58
SIRT1 Suppresses Human T-Cell Leukemia Virus Type 1 Transcription90
Roles of liver-enriched transcription factor CREB-H in hepatocellular carcinoma62
Genes and molecular mechanisms in development43
Vitamin D deficiency is associated with depletion of circulating endothelial progenitor cells and endothelial dysfunction in patients with type II diabetes85
Molecular and cellular characterization of ganglioside-stimulated protein kinase164
A source of restrictive chondroitin sulfates-in encounters of schwann cells and astrocytes in vitro52
In vivo study of asporin, a genetic risk factor for intervertebral disc degeneration60
Chondroitin sulfate proteoglycans (CSPG) and hyaluronan at borders between astrocytes and schwann cells restrict neurite crossing47
cDNA cloning of c33-c antigen gene derived from NS3 region of Chinese HCV genome, expression in Escherichia coli and development of HCV EIA second-generation diagnostic kit.120
Studies on human erythrocyte cholinesterase: (Acetylcholine acetyl hydrolase E.C.3.1.1.7.).188
Accumulation of prelamin A compromises NF-kB-regulated B-lymphopoiesis in progeria mouse model.78
Quantitative asymmetric-detection time-stretch optical microscopy (Q-ATOM) for ultrafast quantitative phase imaging flow cytometry107
A mechanism underlying susceptibility to HBV infection: HBV down-regulate transferase-1 type I interferon receptor 1 via suppressing poly(ADP-ribose)96
Interactions of Hox genes during craniofacial development.56
The genetics of SELEX64
Novel role of proheparanase in regulating synaptic function in the central vestibular circuitry53
Perturbation of GABAergic transmission during a postnatal critical period alters behavior in path integration task38
Structural characterization of crystal-active urinary polyanionic macromolecules69
Cells in the endplate contribute to the maintenance and repair of the inner annulus fibrosus55
Identification and characterization of a novel liver-enriched transcription factor of the bZIP family45
Disruption of the mouse Hoxb3 locus affects ventral body wall development54
Ex vivo generation of myelinating Schwann-cell-like cells from bone marrow-derived neurospheres65
Structure of RPA32 with N-terminus of SMARCAL1 reveals a consensus structural motif shared by RPA32 interacting proteins23
Towards aptamer-mediated malaria diagnostics: structural insight into discriminatory molecular recognition by a DNA aptamer98
Solution of the structure of tetrameric human glucose 6-phosphate dehydrogenase by molecular replacement51
Stem cells in premature ageing56
The fission yeast TACC homolog alp7 is recruited to the spindle pole for bipolar spindle formation 38
Erythrocyte membrane (Ca2+ + Mg2+)-ATPase inhibitor protein and its modulator187
Interplay between ER stress and hypoxia pathways in chondrocytes135
Physicochemical characterization of animal brain ganglioside- stimulated protein kinase47
Early postnatal disturbance of inhibitory transmission in the vestibular nucleus impacts on the thalamic spatial map and navigation behaviors1309
Sox10 mutation affects cochleo-vestibular ganglion gliogenesis69
The Roles of CHOP and GADD34 in the Adaptation of Hypertrophic Chondrocytes to ER Stress55
Development, Growth and Differentiation4
Aberrant activation of ERK/FOXM1 signaling cascade triggers the cell migration/invasion in ovarian cancer cells122
A simple annular puncture model of disc degeneration in the mouse tail52
The Mechanisms of Chondroitin Sulphate Lyases Treatment in Promotion of Axonal Growth90
Histidine-rich protein, HPN and metallothionein: are they similar?65
Molecular consequences of Indian Hedgehog mutations causing brachydactylies in chick neural tube71
Regulatory role of perineuronal nets and semaphorin 3A in the developmental maturation of the central vestibular circuitry80
The molecular basis of Indian hedgehog mutations in digit patterning46
Modulation of plasminogen activator and plasminogen activator inhibitor system in murine macrophage190
Towards remyelination therapy: divergent routes for derivation of alternative glial cell fate from bone marrow stromal cells of adult rats53
Ganglioside-stimulated protein kinase in brain: effects of trisialoganglioside GT1b/detergent mixed micelles on intrinsic enzymic activity50
Functional characterization of the liver-enriched transcription factorCREB-H236
Development and compensation of the gravity sensing system: Implications on neural plasticity93
New approaches to osteoporosis therapy with aptamer-based inhibitors66
Understanding the biological role of isthmin during mouse development and homeostasis60
B lymphocyte development and transcription regulation in vivo64
Deposition of 5-Methylcytosine on Enhancer RNAs Enables the Coactivator Function of PGC-1α82
The role of glycosaminoglycans secreted by the astrocyte cell line DI TNC1 in the regulation of neurite outgrowth67
Regulation of phosphorylation of c-jun N-terminal kinases (JNKs) in neonatal mouse hypoxic ischemic encephalopathy model80
Developmental lumbar spinal stenosis in Southern Chinese: findings from a genome-wide association study69
Molecular characterization of the insertional mouse mutant yellow submarine, Ysb197
The human α2(XI) collagen gene (COL1 1A2): Completion of coding information, identification of the promoter sequence, and precise localization within the major histocompatibility complex reveal overlap with the KE5 gene111
Inorganic polyphosphate triggers upregulation of interleukin 11 in human osteoblast-like SaOS-2 cells79
Transgenic animal and gene targeting technology in Hong Kong: current status and future prospects63
Targeting Notch Signalling to Generate Bone Marrow-derived Schwann Cells for Transplantation in Spinal Cord Injury92
Vertebrate viruses and microRNAs53
ProteoMirExpress: inferring microRNA and protein-centered regulatory networks from high-throughput proteomic and mRNA expression data95
Study of the Taq I Polymorphism of Vitamin D Receptor gene in Lumbar Disc Degeneration in Chinese53
Improved Cell Survival and Paracrine Capacity of Human Embryonic Stem Cell-Derived Mesenchymal Stem Cells Promote Therapeutic Potential for Pulmonary Arterial Hypertension.158
Genetic analysis of alzheimer's disease associated genes: a perspective from abnormal cholesterol metabolism61
The roles of Sox2 and Sox18 in hair type specification and pigmentation171
Corneal epithelial MT1-MMP inhibits vascular endothelial cell proliferation and migration80
Towards specific DNA aptamers which bind and inhibit WWP1 HECT ubiquitin ligase in the osteoblast288
Illuminating the aetiology of Campomelic dysplasia caused by mutation in the transactivation domain of SOX980
Astroglial chondroitin sulfate proteoglycans modulate growth and differentiation of cortical neurons on astrocytes in vitro70
Polyphosphate regulates interleukin-11 levels of SaOS-2 cells61
Raf/MEK/MAPK signaling stimulates the nuclear translocation and transactivating activity of FOXM1206
CRISPR/Cas9 Genome-Editing System in Human Stem Cells: Current Status and Future Prospects170
Genipin-treated chitosan nanofibers as a novel scaffold for nerve guidance channel design80
The phenotype study of PDSS2 conditional knockout mouse71
Loss of MKP3 is associated with cisplatin-resistance and tumorigenicity of ovarian cancer65
Endocannabinoid regulates the efficacy of vestibular inhibitory synapses contributing to the expression of gravity-detection behavior in developing rats67
Roles of Progenitor Cells for Intervertebral Disc Regeneration in 'Healer' Mice100
Renal proximal tubular glycosaminoglycans-isolation, characterization and involvement in calcium oxalate crystallization193
Cadherin 2 is required for intervertebral disc homeostasis and maintenance of vacuolated phenotype in nucleus pulposus cells150
The expression of p21/WAF1/CIP1 is not sufficient to mediate the anti-apoptotic action of Epidermal-Growth-Factor Receptor43
Acid glycosaminoglycans: ion binding and electrophoretic mobility.187
Inorganic polyphosphate as a forgotten molecule in osteoblasts: from synthesis to function64
Integrative approach for omic data analysis and gene regulatory network construction44
Leptin induces CD40 expression through the activation of Akt in murine dendritic cells101
Genetic Study in AD, The Way Forward9
A distinct Hox code for the branchial region of the vertebrate head100
GABAergic transmission in the critical period impacts on the thalamic spatial map and navigation behavior1297
Molecular machinery of macroautophagy and its deregulation in diseases91
Nucleic acids aptamers for malaria diagnosis - discovery, structure and application64
A mutation in avian influenza H5 hemagglutinin with efficient packaging into lentiviral backbone and its implications on receptorbinding288
Effect of p53 on centrosome amplification in prostate cancer cells123
The Y271 and I274 amino acids in reverse transcriptase of human immunodeficiency virus-1 are critical to protein stability115
Induction of osteo-chondroprogenitors formation during transcription factor-mediated reporgramming process75
The sarcoplasmic reticulum luminal thiol oxidase ERO1 regulates cardiomyocyte excitation-coupled calcium release and response to hemodynamic load57
Prediction of osteoporosis candidate genes by computational disease-gene identification strategy85
PRMT1 activates leukemic stem cell program in MLL-rearranged leukemia48
Sonic hedgehog (SHH) promotes proliferation and maintains multi-potency of enteric neural crest stem cells (NCSCs)68
Expression of collagen and aggrecan genes in normal and osteoarthritic murine knee joints93
Studying the roles of mouse Sox10 by conditional gene targeting164
Histological and mechanical property abnormalities of bone fracture healing in the absence of collagen type X85
Different cis-regulatory DNA elements mediate developmental stage- andtissue-specific expression of the human COL2A1 gene in transgenicmice188
Cell therapy for remyelination: divergent routes for derivation of alternative glial cell fates from adult bone marrow stromal cells100
Nano-scale morphology of disc collagens and their correlation with disc mechanics90
MTI-MMP Supports Development Niche of B Cell Lineage in Bone Marrow51
A study on an enhancer-like element in Escherichia coli.71
Aptamer-mediated inhibition of Mycobacterium tuberculosis polyphosphate kinase 2217
Induced pluripotent stem cells and neurological disease models78
Role of double-stranded RNA-binding protein PACT in MDA5-mediated antiviral innate immune response221
HOXB5 expression is spatially and temporarily regulated in human embryonic gut during neural crest cell colonization and differentiation of enteric neuroblasts129
How Has Genetics Changed Our Understanding of Disc Degeneration?101
A versatile microscopy to study biological pattern formation108
Rapid assembly of multiple-exon cDNA directly from genomic DNA92
Spatiotemporal relationship between chondroitin sulfates and chondroitin 6-sulfotransferase in the neuroepithelium during mouse hindbrain development58
Over-expression of Hoxb3 affects sensory neuron differentiation and inner ear morphogenesis86
Combination of MRI hippocampal volumetry and arterial spin labeling MR perfusion at 3-Tesla improves the efficacy in discriminating Alzheimer's disease from cognitively normal elderly adults101
Large scale screening of transcription regulatory sequences recognised by Hox homeodomain proteins54
Investigating the effects of glucose levels on PDZD2 levels in rat insulinoma INS-1E cells31
The Roles of Sox2 and Sox18 in Hair Follicle Specification55
Developmental maturation of ionotropic glutamate receptor subunits in rat vestibular nuclear neurons responsive to vertical linear acceleration98
Research on the genetic basis of human split hand/foot malformation 135
Attempts to locate the expression of chondroitin sulfate during embryonic hindbrain development in mouse63
TORC1 and TORC2 coactivators are required for tax activation of the human T-cell leukemia virus type 1 long terminal repeats94
Dissection of biophysical properties and biological activities of Bet/RecT family DNA recombination proteins122
Genetic risk factors for late-onset Alzheimer's disease in Chinese252
Effect of platelet-rich plasma on a rabbit model of nicotine-compromised bone healing103
D225G mutation in hemagglutinin of pandemic influenza H1N1 (2009) virus enhances virulence in mice145
Activation of AMPK inhibits cervical cancer cell growth through AKT/FOXO3a/FOXM1 signaling cascade97
Increased 6-sulfated chondroitins correlate with upregulated expression of chondroitin 6-transferase mRNA in post-crush sciatic nerves of adult rats.66
Identification and validation of the cellular targets of virus-encoded microRNAs.84
Construction of new DNA vectors based on promoters of Epstein-Barr Virus-encoded small RNAS for expression of small hairpin RNAS in mammalian cells52
Down-regulation of two novel genes by hypoxic-ischaemic encephalopathy in neonatal mouse78
Glycosaminoglycan control of oxalate transport across cultured renal cells. In: H.-G. Tiselius (ED)65
Retinoic acid alters hindbrain Hox code and induces transformation of rhombomeres 2/3 into a 4/5 identity153
Marfan syndrome: Absence of type I or III collagen structural defects in 25 patients106
The beneficial effects of Qigong and conventional exercise on blood pressure and anthropometric indices in type 2 Chinese diabetic patients112
Identifying therapeutic chemical agents for osteoarthritis by high throughput screening66
Smad4 pathway inhibits sensory formation in the mouse cochlea35
Melatonin MT 1 receptor-induced transcriptional up-regulation of p27 Kip1 in prostate cancer antiproliferation is mediated via inhibition of constitutively active nuclear factor kappa B (NF-κB): Potential implications on prostate cancer chemoprevention and therapy83
Derivation of oligodendrocyte precursors from bone marrow stromal cells for remyelination therapy80
Expression of HIS50 Ag: a rat homologue of mouse heat-stable antigen and human CD24 on B lymphoid cells in the rat63
Studying the role of epidermal growth factor in chondrogenesis70
Molecular studies of rat {221}-globin gene cluster198
Stimulation of in vitro mineralization on strontium-containing hydroxyapatite bioactive bone cement68
Herpes simplex virus type 1 Us11 suppresses innate antiviral immune response by preventing PACT-induced activation of RIG-I65
IPGWAS: An integrated pipeline for rational quality control and association analysis of genome-wide genetic studies72
Cell fate determination in skeletal development and growth55
Differential regulation of FOXM1 isoforms by RaF/MEK/ERK signaling212
Homeotic arm-to-leg transformation associated with genomic rearrangements at the PITX1 locus101
Tissue distribution of promyelocytic leukaemia (PML) proteins and PML nuclear domains in rat and man182
Cloning and characterizing PAC1 receptor-Hop1 splice variant in goldfish (Carrasius auratus)83
KGG: a systematic biological knowledge-based mining system for genome-wide genetic studies100
Association of Asporin D14 allele with lumber disc degeneration in asians109
Maternal cold inducible RNA binding protein is required for embryonic kidney formation in Xenopus laevis120
A splice-site mutation leads to haploinsufficiency of EXT2 mRNA for a dominant trait in a large family with multiple osteochondromas.150
Chondroitin sulfate proteoglycans in astrocyte-Schwann cell cocultures limit neurite extension and crossing of cellular boundaries101
KIF5b is essential for growth plate organization, cytokinesis and chondrocytes differentiation69
A critical assessment of the RNAse protection assay as a means of determining exon sizes99
Structural analysis of zinc-substituted cytochrome c75
A dominant interference collagen X mutation disrupts hypertrophic chondrocyte pericellular matrix and glycosaminoglycan and proteoglycan distribution in transgenic mice107
High resolution autofocus for spatial temporal biomedical research62
Requirement for Pbx1 in skeletal patterning and programming chondrocyte proliferation and differentiation64
In memoriam: Kuan-Teh Jeang, MD PhD (1958–2013)48
KIF5b is essential for growth plate organization and cytokinesis49
Resonance assignments for the endosomal adaptor protein p14.76
Analysis of the heterogeneity of human collagens by two-dimensional polyacrylamide-gel electrophoresis95
A stuI RFLP in the human COL11A2 gene83
Sox10 mediates proliferation and migration behavior of enteric neural crest cells62
Inhibition of malignant trophoblastic cell proliferation in vitro and in vivo by melatonin100
Sox2 is required for sensory organ development in the mammalian inner ear140
A base substitution in the exon of a collagen gene causes alternative splicing and generates a structurally abnormal polypeptide in a patient with Ehlers-Danlos Syndrome Type VII138
Linkage analysis on familial early-onset degenerative disc disease(DDD)99
The Role of Indian Hedgehog in Chondrocyte Hypertrophy55
Leucine-rich repeat and WD repeat-containing protein 1 is recruited to pericentric heterochromatin by trimethylated lysine 9 of histone H3 and maintains heterochromatin silencing57
Identification of molecular determinants for efficient H5pp production111
Sox9-regulated cell plasticity in colorectal metastasis is attenuated by rapamycin68
Methylation and expression of human pepsinogen genes in normal tissues and their alteration in stomach cancer89
Postnatal expression of TrkB receptor in rat vestibular nuclear neurons responsive to horizontal and vertical linear accelerations115
Human T-cell leukemia virus oncoprotein Tax represses nuclear receptor signaling by targeting transcriptional coactivator TXBP15166
Parallel, Beneficial Genome Reduction During Adaptation of Experimental Populations28
Proheparanase and AMPA receptor trafficking in synaptic plasticity68
Manipulating the mouse genome to understand human disease52
Use of a bridge model to test the effect of neural glycosaminoglycans on regrowth of transected sciatic nerves in adult guinea pigs68
Tissue-specific transcriptional regulation of Sox2200
A novel two-step recombinogenic engineering method for bacterial artificial chromosome manipulation51
Changes in perineuronal net components correlate with functional modifications of vestibular nuclear neurons in the rat63
The upregulation of GADD153 expression and N-(4-hydroxyphenyl)retinamide (4HPR)-induced apoptosis52
Investigating the protective role of FOXM1 against oxidative stress and DNA damage in human embryonic stem cells55
Genetic analyses of terminal differentiation of hypertrophic chondrocytes147
Next generation sequencing has lower sequence coverage and poorer SNP-detection capability in the regulatory regions196
Tspyl2 is involved in cellular stress response and brain function54
A novel non-turing mechanism of spot pattern formation53
Identification of sperm-binding proteins in the ventral prostate of the golden hamster60
Understanding Molecular Mechanism of Laminopathy-based Premature Ageing48
Association of the cholesterol 24S-hydroxylase polymorphism with Alzheimer's disease in Chinese85
Isolation and characterization of an abortifacient protein, momorcochin, from root tubers of Momordica cochinchinensis (family cucurbitaceae).150
Functional Study of Heparanase in the explant cultures of rat dorsal root ganglia88
Genetic susceptibility of intervertebral disc degeneration among young Finnish adults112
MMP14 regulates the lineage progression of hypertrophic chondrocytes51
Endophilin B1. Guarding the gate to destruction52
Transgenic mouse model of human chondrodysplasia191
Computational construction of the downstream network of Pax6 in AD neuronal death model46
Regeneration of the nucleus pulposus cells for Degenerative Disc Disorder43
Mutations in collagen IX as genetic predisposing factors for degenerative disc disease in Southern Chinese102
Accelerated Senescence in Degenerate Intervertebral Disc of Laminopathy-based Premature Aging Mouse Model114
Differential regulation of FOXM1 isoforms by RAF/MEK/ERK signaling59
The Solution Structure of Cytochrome b5 Mutant(E44A/E48A/E56A/D60A)94
Expression of chondroitin sulfates in the developing hindbrain: contributions to plasticity182
The role/s of type IIA procollagen in BMP (Bone morphogenetic protein) signaling.44
Acarbose in NIDDM patients with poor control on conventional oral agents: A 24-week placebo-controlled study134
Academy of Mathematics and Systems Science17
A study of the quaternary structure of human glucose-6-phosphate dehydrogenase (G6PD)217
Hoxb1 cooperates with Gli to mediate sonic hedgehog signaling in hindbrain neurogenesis58
Bioavailable testosterone predicts a lower risk of Alzheimer's disease in older men133
Defining the role of Sox9 in early development by tissue specific gene inactivation63
Nitrogen Plasma Immersion Ion Implanted Nickel Titanium Alloys For Orthopedic Use53
A simplified and improved method for the efficient double-stranded sequencing of mini-prep plasmid DNA84
Functional characterization of tyrosine phosphatase non-receptor 21, anovel modulator of ErbB4/NRG3193
dsu functions in a MYO5A-independent pathway to suppress the coat color of dilute mice96
Bioinformatics study of the lineage and tissue specificity of genes and gene expression262
The role of the AU-rich element in the mRNA of the stress-inducible protein CHOP/Gadd15354
Hypertrophic chondrocytes become osteoblasts and osteocytes contributing to endochondral bone formation75
Protein and Gene Expression Profiles of the Intervertebral Disc51
Upregulation of NF-kB signaling pathway in hepatocellular carcinoma67
Decellularization of chondrocyte-encapsulated collagen microspheres: A three-dimensional model to study the effects of acellular matrix on stem cell fate132
Kinesin-1 is involved in chondrocytes adhesion to extracellular matrix and motility100
Chemical modification of immunoglobulins and the effects on antigen binding site affinity212
Quantitative characterization of mouse embryonic stem cell self-renewal, differentiation and dedifferentiation56
Transient enrichment of 6-sulphated isomers of chondroitin in post-crush sciatic nerves of adult guinea pigs66
Molecular mechanism of disease for spondyloepiphyseal dysplasia tarda-effect of mutations on sedlin structure and function61
In vitro derivation of myelinatiog Schwann cells for use in chitosan-based nerve guidance channels261
Combination of overlapping bacterial artificial chromosomes by a two-step recombinogenic engineering method.84
Nuclear and cell membrane surface area alteration in hexamethylene bisacetamide (HMBA) induced human colonic carcinoma cell line (LoVo)65
Discovering the crucial link for sensory development in the inner ear23
A Bam H1 RFLP in the human α2(X1) (COL 11A2) gene68
Diadenosine polyphosphate analog controls postsynaptic excitation in CA3-CA1 synapses via a nitric oxide-dependent mechanism106
Influence of low-dose nicotine on bone healing81
MT1-MMP regulates central nervous system development through Notch signaling186
A fast and accurate SNP detection algorithm for next-generation sequencing data60
The effect of severity of disc degeration on mesenchymal stem cell's ability to regenerate the intervertebral disc53
Generation of a mouse model to study ADAMTS-5 as a genetic risk factor for intervertebral disc degeneration60
Mitotic checkpoint: A therapeutic target in the treatment of human cancer68
Involvement of PDZD2 in Regulating Pancreatic Beta Cell64
The roles of perineuronal nets and heparanase in synaptic plasticity at the hippocampus85
Expression and functional studies of a SH3 domain containing gene family, EEN family, and their implications in leukemogenesis53
Kif5b interaction with NMDA receptors regulates neuronal function234
Development of live recombinant salmonella oral vaccine against avian influenza viruses85
Tissue specific expression studies on a vagal neural crest enhancer element of the mouse Hoxb3 gene in the development of the entericnervous system178
On the mechanisms of bananin activity against severe acute respiratory syndrome coronavirus104
Genome-wide association study of adolescent idiopathic scoliosis in southern Chinese81
The role of cyclooxygenase 1 and 2 in fracture healing56
Genetics95
Foxa2 minimal notochord enhancer element mediates Cre expression in the node and notochord88
Regeneration of degenerated intervertebral disc using allogeneic Mesenchymal stem cells encapsulated in self-assembling peptide hydrogel58
Perineuronal chondroitin sulfates and semaphorin 3A regulate postnatal maturation of the vestibular circuit for gravity detection49
Understanding innate immune response to influenza A viruses using reverse genetics and TALEN technology68
Nucleic acid aptamers – tools for chemical biology57
Vertebroplasty by use of a strontium-containing bioactive bone cement165
ROS mediates 4HPR-induced posttranscriptional expression of the Gadd153 gene98
Co-evolution of transcription factors and their binding sites205
Procollagen IIA regulates BMP/TGFb signaling in patterning the heart and its major vessels96
A proposed model for UPR-mediated cellular survival and cell death57
Hoxb3 mutation leads to interleukin-6 dependent plasmacytoma67
The effects of cyclooxygenase-2 selective non-steroidal anti-inflammatory drugs (NSAIDs) in fracture repair46
Understanding Hindbrain Neurogenesis by Analysis of a Hoxb3Transgenic Mouse Mutant SL267
Maturation of glutamatergic transmission in the vestibulo-olivary pathway impacts on the registration of head rotational signals in the brainstem of rats120
The enzymatic mechanism mediating the breakdown of glycogen in hypoxic tumor cells48
Development of an effective method to tag escherichia coli chromosomal genes based on recombineering48
A proteomic approach to study the molecular mechanisms of the unfolded protein response in the endoplasmic reticulum of chondrocytes52
Use of chondroitin sulphate lyases in combination for achieving maximal activity: implication for nerve regeneration58
Pertussis toxin, but not tyrosine kinase inhibitors, abolishes effects of U-50488H on [Ca2+](i) in myocytes62
Regulation of the mouse Hoxb-3 gene in the mindbrain67
The role of Uhrfl in hedgehong signaling39
Loss of β-catenin in hypertrophic chondrocytes affects trabecular bone formation47
Study of enhanced corrosion resistance and biocompatibility by plasma implantation of nickel-titanium alloys: an in-vitro and surface chemcial analysis56
Dosage-dependent requirement of sedlin component of the TRAPP complex in mouse embryonic development74
The support of human genetic evidence for approved drug indications132
Utility of Hoxb2 enhancer - mediated Cre activity for functional studies in the developing inner ear69
Change in the composition of perineuronal nets of central vestibular neurons following unilateral labyrinthectomy63
RNAi in Xenopus embryos103
Effects of down-regulating hypoxia-inducible factor-1 alpha on retinal pigment epithelial cells under hypoxia71
Structural analysis of thymidylate synthase in nematodes: ascaris suum & caenorhabditis elegans192
Linkage analysis on familial early-onset degenerative disc disease67
DNA sequence analysis of the Hind III M fragment from Chinese vaccine strain of vaccinia virus75
Chitosan fibers for culturing aligned Schwann Cells for nerve regeneration53
An integrated metalloproteomic analysis depicts the proteomic features of helicobacter pylori in response to Bi(III)75
Association between genetic polymorphisms and periodontitis In Hong Kong Population69
The role of chondroitin sulfate moieties on trigeminal motor neuron migration in embryonic rat hindbrain57
Serglycin in the HL-60 degranulation product retains its sulfated chondroitin/dermatan moieties and affinity for neutrophil elastase66
Study of signaling and regulatory networks by computational methods202
Beyond the human glucose-6-phosphate dehydrogenase (G6PD) gene: protein structure and function analyses81
Type IIA procollagen: A positive regulator of nodal signaling during embryogenesis62
Sputum neutrophil activity in stable bronchiectasis69
Aberrant signal peptide cleavage of collagen X in schmid metaphyseal chondrodysplasia. Implications for the molecular basis of the disease121
Uncoupling protein-2 mediates neuronal survival by leptin against mitochondria dysfunction and ATP deficiency76
Understanding the role of KIF5B in long bone development and chondrocyte cytokinesis210
Functional studies of SOX9 in mouse development214
Cdk5 is involved in BDNF-stimulated dendritic growth in hippocampal neurons69
From understanding synaptic plasticity to the development of cognitive enhancers72
Transcriptional regulation of yeast peroxiredoxin gene TSA2 through Hap1p, Rox1p, and Hap2/3/5p177
Identification of distinct DNA elements from the human a1(II) collagen gene directing tissue specific expression during development46
Heparanase expression in regenerating peripheral nerves and dorsal root ganglion explant cultures41
Id1 upregulates aurora kinase A, induces centrosome abnormalities, polyploidy and disrupts microtubule integrity83
The softer art of enzymology (Book Review)71
Neural glycosaminoglycans and their effects on post-traumatic regrowthof sciatic nerves in adult guinea pigs178
Functional roles for Irx3 and Irx5 in skeletal development43
Cadherin 2/N-cadherin regulates notochordal cell function and intervertebral disc homeostasis69
Association studies of intervertebral disc disease with genes in the aggrecan degradation pathway77
Role of Epstein-Barr virus-encoded BART microRNAs in viral infection and transformation of nasopharyngeal epithelial cells29
PACT targeting is a novel viral strategy of innate immune evasion49
Abnormal type I collagen metabolism by cultured fibroblasts in lethal perinatal osteogenesis imperfecta107
Inhibition of β-ionone on SGC-7901 cell proliferation and upregulation of metalloproteinases-1 and -2 expression85
Procollagen IIA regulates BMP signaling in heart development via a regulatory loop24
DNA aptamers as inhibitors of E3 ubiquitin ligase WWP165
In vitro evaluation of alginate encapsulated adipose-tissue stromal cells for use as injectable bone graft substitute133
Heparanase upregulation in astrocytes and macrophages recruited to the injured spinal cord85
Identification and characterization of a novel liver-enriched transcription factor of the bZIP family72
Crystal-suppressive modulators of separated urinary polyanions47
Increased vulnerability to liver injury is associated with decreased mitochondrial activities in adiponectin knockout mice: potential roles of UCP2 in the hepatoprotective functions of adiponectin68
Raf/MEK/MAPK signaling stimulates the nuclear translocation and transactivating activity of FOXM1c77
CIS-acting DNA controlling elements of the human alpha 1(II) collagen gene205
Endochondral bone formation and chondrodysplasia: role of collagen X and molecular mechanisms40
1H NMR study of 2-methylimidazole binding to cytochrome c: A comprehensive investigation of the role of the methyl substituent on the ligand binding affinity and heme electronic structure in imidazole-cytochrome c complexes117
Identification of factors influencing strand bias in oligonucleotide-mediated recombination in Escherichia coli126
Prelamin A regulates DNA repair through histone modifications45
Correlating protein structure with disease - understanding the mechanism of SEDT99
Stimulus-specific adaptation at the synapse level in vitro66
Roles of epstein-barr virus-encoded miR-BART microRNAs in nasopharyngeal epithelial tumorigenesis80
UHRF1 double tudor domain and the adjacent PHD finger act together to recognize K9me3-containing histone H3 tail51
Male Genital Tract Antioxidant Enzymes: Their Source, Function in the Female, and Ability to Preserve Sperm DNA Integrity in the Golden Hamster133
p53 represses the transcription of mitotic checkpoint gene MAD152
Chondroitin sulfates enriched in the developing rat hindbrain restrict commissural projections of vestibular neurons93
The involvement of perineuronal semaphorin 3A and chondroitin sulfates in regulating maturation of the central vestibular circuitry35
Visualizing the proteome of escherichia coli by labeling E. coli chromosomal genes with fluorescent tags49
Stem Cells and Aging26
Development of aptamer-nanoparticle conjugates as a new approach to malaria diagnosis403
Secreted PDZD2 exerts concentration-dependent effects on the proliferation and function of pancreatic beta cells.101
Elucidation of ganglioside-binding motif in cholera toxin b-subunit40
The gene for the α2 chain of the human fibrillar collagen type XI (COL11A2) assigned to the short arm of chromosome 668
Control of syndecan-1 shedding to limit smoking-related neutrophilic inflammation250
Inorganic polyphosphate and its impact on osteoblast function, signaling and gene expression56
Tissue-specific expression and long-term deposition of human collagen VII in the skin of transgenic mice: Implications for gene therapy102
Electrophoretic studies on matrix vesicles from rabbit growth plate cartilage105
BDNF-mediated GABAergic transmission in the rat vestibular nucleus regulates the developmental recognition of spatial orientation57
Hoxb1 cooperates with GL1 to mediate sonic hedgehog signaling in hindbrain neural progenitor cell fate determination73
From Discrete Molecules to Supramolecular Assemblies – An Interplay of Electrostatics, π-π Stacking and Metal-Metal Interactions13
Molecular and mutation analysis of hereditary multiple exostoses80
The role of negative superhelicity and length of homology in the formation of paranemic joints promoted by RecA protein96
Rewriting concepts on the ontogeny of bone cells36
Translation of embryonic-chick tendon procollagen messenger ribonucleic acid in two cell-free protein-synthesizing systems82
Piezoelectric quartz crystal biosensor for SARS coronavirus helicase based on aptamer61
Cell-to-cell spreading of RNA interference in mammalian cells71
Expression and protein-binding studies of the EEN gene family, new interacting partners for dynamin, synaptojanin and huntingtin proteins109
Genetic approach to Study the Role of MT1-MMP in Tumor Development in Vivo55
Expression of chondroitin sulfate proteoglycans in the chiasm of mouse embryos82
Cyst formation: mathematical model and data analysis47
Histidine-rich proteins in prokaryotes: metal homeostasis and environmental habitat-related occurrence102
Analysis of nucleosomal deoxyribonucleic acid in a higher plant88
Receptors of glutamate and neurotrophin in vestibular neuronal functions100
Developmental assembly of neural correlates for head direction117
Construction of new DNA vectors based on promoters of Epstein-Barr virus-encoded small RNAs for expression of small hairpin RNAs in mammalian cells55
New bone formation with osteoprogenitor cells confined in sodium alginate microcapsules162
Expression of heparanase in newborn mouse growth plates61
Arabidopsis cytosolic acyl-CoA-binding proteins ACBP4, ACBP5 and ACBP6 have overlapping but distinct roles in seed development95
Expression and purification of mutated hpn protein, and studies of function of cysteine residues in hpn75
Abnormal chondroctye differentiation in transgenic mice expressing a schmid metaphyseal chondrodysplasia Col10al mutation85
A characterization of the in vitro effects of metal ions on thioredoxin reductase123
ER-stress signaling and chondrocyte differentiation in mice168
Constructing epigenetic regulatory networks from high throughput gene expression and ChIP-seq data33
Stable derivation of Schwann cells from human bone marrow stromal cells51
Expression and characterization of a histidine-rich protein, Hpn: Potential for Ni2+ storage in Helicobacter pylori134
Abnormal enteric nervous system development in a Sox10-EGFP mutant mouse115
Oligodendrocyte precursors – in vitro derivation from bone marrow stromal cells and use in remyelination therapy47
Growth-inhibitory and facilitatory aspects of chondroitin sulfates in developing neural environments73
MT1-MMP inactivates ADAM9 to regulate FGF signaling43
A Novel Neural Response Algorithm for Protein Function Prediction53
Dissect Kif5b in nuclear positioning during myogenesis: The light chain binding domain and the autoinhibitory peptide are both indispensable66
Towards remyelination therapy: derivation of oligodendrocyte precursor cells from bone marrow stromal cells44
Quantitative characterization of mouse embryonic stem cell self-renewal, differentiation and dedifferentiation66
Stripe formation in bacterial systems with density-suppressed motility119
Interspecies transmission and emergence of novel viruses: lessons from bats and birds.279
Roles of kinesin-1 mediated intracellular transport in skeletal development77
Novel function of HOXB3 gene in regulation B lymphopoiesis48
Developmental modulation of long-term plasticity at vestibular GABAergic synapses106
Kinesin-1 in skeletal muscle210
Mitotic checkpoint defects in human cancers and their implications to chemotherapy122
Altered matrix structure and bone density in collagen X null mice65
Comparative and quantitative proteomics reveal the adaptive strategies of oyster larvae to ocean acidification76
Hoxb3 negatively regulates Hoxb1 expression in mouse hindbrain patterning140
Impact of collagen type X deficiency on bone fracture healing194
Deficiency of novel inhibitory neurotransmitter carbon monoxide in aganglionic bowel of Hirschsprung's disease.76
Differentiation and progression of interzone cells as progenitors of articular chondrocytes in joint formaiton56
ER stress in the growth plate58
Isolation and characterization of cell subpopulation with stem cell properties in human and monkey intervertebral disc (ivd)116
Epigenetic dysregulation of leukemic Hox code in MLL-rearranged leukemia mouse model83
Establishment of stable infection of Epstein-Barr Virus in premalignant nasopharyngeal epithelial cells83
Changes in ornithine decarboxylase activity and polyamine levels during the growth of Tetrahymena thermophila cultures91
A Sox10-GFP mutant mouse model for the study of abnormal enteric nervous system development in Hirschsprung disease226
Inhibiting sclerostin with a nucleic acid aptamer as a new approach to osteoporosis therapy68
Global gene expression changes during chondrocyte adaptation to ER stress84
Current trend of annotating single nucleotide variation in humans – A case study on SNVrap84
Molecular basis for increased bone formation in a mouse model expressing mutant type X47
PDZ-domain containing-2 (PDZD2) is a novel factor that affects the growth and differentiation of human fetal pancreatic progenitor cells87
Applicability of intraoperative parathyroid hormone assay during thyroidectomy126
DNA repair, human diseases and aging100
Perturbation of biogenesis and targeting of Epstein-Barr virus-encoded miR-BART3 microRNA by adenosine-to-inosine editing83
Mesenchymal stem cells mediate disk regeneration by suppression of fibrosis in nucleus pulposus119
Vestibular afferent innervation in the vestibular efferent nucleus of rats88
Aptamer-directed DNA tweezers58
Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33.121
Expression and Purification of Mutated hpn Protein, and Studies of Function of Cystein Residues in hpn69
Next generation sequencing has lower sequence coverage and poorer SNP-detection capability in the regulatory regions76
Genetic linkage analysis of early onset degenerative disc disease in Southern Chinese78
Functional dissection of an IFN-α/β receptor 1 promoter variant that confers higher risk to chronic hepatitis B virus infection135
Prioritizing genes responsible for host resistance to influenza using network approaches97
Organizational analysis of elav gene and functional analysis of ELAV protein of Drosophila melanogaster and Drosophila virilis101
How Reliable Are the Reported Genetic Associations in Disc Degeneration?56
Activation of the Jak3 pathway is associated with granulocytic differentiation of myeloid precursor cells92
Cellular localization of heparanase in the normal versus injured spinal cord of adult rats70
Peroxiredoxin-null yeast cells are hypersensitive to DNA-damaging agents47
Expression, purification and preliminary crystallographic analysis of Pseudomonas aeruginosa RocR protein89
Synthetic peptides outside the spike protein heptad repeat regions as potent inhibitors of SARS-associated coronavirus104
Linkage analysis on familial early-onset degenerative disc disease (DDD)81
Mapping a genetic modifier for heart defects in Type IIA procollagen deficient mutant mice56
Differential expression, localization and activity of two alternatively spliced isoforms of human APC regulator CDH190
Towards a universal aptamer diagnostics platform38
Short Read Mapping for Exome Sequencing105
Discriminatory targeting of ADAMTS aggrecanases for high-specificity therapeutics development for degenerative disc disease30
RNA transcription affects strand bias in single strand oligonucleotide-mediated mutagenesis74
Aptameric inhibition of E3 ubiquitin ligase WWP1 for osteoporosis therapy62
Intervertebral disc degeneration on MRI is associated with low back pain: a population-based study55
Nanostiffness of Collagen Fibrils Extracted From Osteoarthritic Cartilage Characterized with AFM Nanoindentation112
The role of Sox2 in mouse hair morphogenesis59
Chronic Cardiovascular Disease-Associated Gene Network Analysis in Human Umbilical Vein Endothelial Cells Exposed to 2,3,7,8-Tetrachlorodibenzo-p-dioxin102
(ii) Family-based linkage and case control association studies228
Both HIF-1α and HIF-2α are present in prenatal and postnatal nucleus pulposus cells73
Diverse assessment and active student engagement sustain deep learning: A comparative study of outcomes in two parallel introductory biochemistry courses76
Backbone dynamics measurements on leukemia inhibitory factor, a rigid four-helical bundle cytokine74
Engineering Tumor-killing Salmonella against Breast Cancer76
Study of DNA aptamers binding H5N1 virus nucleoprotein60
Structure and Biology of the Intervertebral Disk in Health and Disease112
Impaired chromatin modification interferes with double-strand break repair in accelerated aging syndrome50
Identification of sclerostin interacting partners: steps towards Osteoporosis Therapy with aptamer-based inhibitors152
Abnormal IHH signaling affects distal digit patterning in a mouse model with brachydactyly type A1109
Development of neural correlates of linear motion in the rat vestibular nucleus74
Age dependent association of the COL9A2 Trp2 allele with intervertebral disc degeneration, annular tears and end-plate herniations80
Basonuclin regulates a subset of ribosomal RNA genes in HaCAT cells78
Genetic association studies in lumbar disc degeneration: a systematic review64
Characterizing the re-activated Ihh singling in 13del programming chondrocytes52
Loss of MT1-MMP affects CNS development36
The mouse model and human disease (Sequel): Cancer49
Commissural projection from the vestibular nucleus in rat embryos: role of chondroitin sulfates64
Probing the molecular mechanisms of how polymorphisms in Cerberus-likeresult in low bone mineral density212
Computational construction of the downstream network of Pax6 in AD neuronal death model47
Histone H4 lysine 16 hypoacetylation is associated with defective DNA repair and premature senescence in Zmpste24-deficient mice144
iCartiGD: the Integrated Cartilage Gene Database106
Uncoupled angiogenesis and osteogenesis in nicotine-compromised bone healing80
Hoxb3 deficiency impairs B lymphopoiesis in mouse bone marrow121
Isolation of mouse Hoxb-3 protein binding sequences: a whole genome approach160
The mouse model and human disease (sequel)61
Schwann cells derived from bone marrow stromal cells – in vitro study with dorsal root ganglia and in vitro study with peripheral nerve conduits65
Management of tracheobronchial obstruction in infants using metallic stents: long-term outcome102
Regulation of UHRF1 post transcriptional modifications in DNA damage and cell cycle45
Response properties of Y group neurons to crossed otolith inputs in the cat82
The role of kreisler in segmentation during hindbrain development88
In vitro study of regulation of IL-6 production in bronchiectasis126
Physicochemical characterization of brain ganglioside-stimulated protein kinase204
Thermodynamic and kinetic aspects of metal binding to the histidine-rich protein, Hpn125
Immunostimulatory function of measles virus defective interfering RNA54
An essential role for Sox2 in inner ear development69
Time-lapse imaging of planarian regeneration83
Genome-wide copy number analysis uncovers a new HSCR gene: NRG3191
Hemagglutinin of influenza A virus binds specifically to cell surface nucleolin and plays a role in virus internalization77
SOX9 elevation in the prostate promotes proliferation and cooperates with PTEN loss to drive tumor formation96
Angiostrongylus cantonensis: Characterization of Thymidylate Synthetase103
Neutrophil elastase: switch from stored form to unopposed form following neutrophil degranulation in inflamedenvironments141
Dissecting the mechanism of how mycobacterium tuberculosis polyphosphate kinase 2 binds to polyphosphate68
Predicting Mendelian Disease-Causing Non-Synonymous Single Nucleotide Variants in Exome Sequencing Studies123
Molecular cloning characterization and purification of rat pro- and mature heparanase61
Involvement of Pdzd2 in the regulation of pancreatic beta-cell functions210
Severe acute respiratory syndrome coronavirus nucleocapsid protein does not modulate transcription of the human FGL2 gene76
Elevated TAK1 augments tumor growth and metastatic capacities of ovarian cancer cells through activation of NF-κB signaling79
Dual specific antibody co-targeting HIV-1 gp120 and gp41 inhibits virus entry by blocking the shedding of gp12058
Sufu defines the balance of hindbrain progenitor cells maintenance and differentiation85
Eya1 interacts with Six2 and Myc to regulate expansion of the nephron progenitor pool during nephrogenesis75
Involvement of proheparanase and peri-synaptic heparan sulfate proteoglycan in synaptic plasticity to regulate AMPA-type glutamate receptor trafficking70
The liver-enriched transcription factor CREB-H is a growth suppressor protein underexpressed in hepatocellular carcinoma116
Craniofacial abnormalities in transgenic mice with ectopic expression of the Hoxb-3 gene214
Single nucleotide polymorphisms of complement component 5 and periodontitis79
Post-translational modification of heterologously expressed Streptomyces type II polyketide synthase acyl carrier proteins98
Study of the Impact of Sox10 Mutation on the Development of Enteric Nervous System in a Mutant Mouse Model Generated by Gene Targeting61
Notch signaling mediates the switch to fate commitment of bone marrow-derived Schwann cells56
Lethal perinatal osteogenesis imperfecta due to the substitution of arginine for glycine at residue 391 of the α1(I) chain of type I collagen79
Injury-induced sequential transformation of notochordal nucleus pulposus to chondrogenic and fibrocartilaginous phenotype in the mouse178
Mechanisms Underlying Chondrocyte Reprogramming Surviving ER Stress60
Epigenetic reprogramming of fibroblasts into osteo-chondroprogenitors77
Development of novel viral promoter-driven DNA vectors for expression of siRNAs to mediate RNA interference in mammalian cells54
Reply47
Overcoming axon-restrictive chondroitin supphates with chondroitin sulphate lyases90
A novel neural response algorithm for protein function prediction52
The dual role of combinatorial chondoritinase in overcoming the chondroitin sulfate barrier39
The role of Prkci in the development of notochord58
Characterization of intracellular transportation in KbcU-mutant purkinje cells54
A novel PS1 case of variant Alzheimer’s Disease with Spastic Paraplegia: the search for a gene-modifier59
Sox2 is Required for Sensory Organ Development in the Inner Ear62
PS1 Alzheimer's disease family with spastic paraplegia: The search for a gene modifier87
Allelic variation of collagen IX as genetic predispositing factors for degenerative disc disease in Southern Chinese87
Regulation of ubiquitination and degradation of CRTC1 transcriptional coactivator by salt-inducible kinase SIK155
Type IIA Procollagen: A Regulator of Nodal Signaling59
An essential role for type IIA procollagen in mouse development47
Structure and function of 5'-nucleotidase of the rat brain171
Amyloid pathology in spinal cord of the transgenic Alzheimer's disease mice is correlated to the corticospinal tract pathway100
Overexpression of soluble TRAIL induces apoptosis in human lung adenocarcinoma and inhibits growth of tumor xenografts in nude mice111
A powerful conditional gene-based association approach implicated functionally important genes for schizophrenia72
Effects of nucleus pulposus cell-derived acellular matrix on the differentiation of mesenchymal stem cells106
Extracellular matrix and stem cell niche in the regenerating planarian73
Functional studies on sedlin67
Spatiotemporal expression of cadherin 2 in the notochordal nucleus pulposus during development and aging of murine intervertebral disc56
PDZD2, a candidate gene for brachdactyly type A1, encodes a secreted protein that negatively modulates hedgehog signalling65
Ectopic expression of Hoxb3 in otic vesicle causes abnormal ear development60
Association of the asporin D14 allele with lumbar disc degeneration140
Subcellular localization of EEN/endophilin A2, a fusion partner gene in leukaemia124
Application of bioinformatics on gene regulation studies and regulatory network construction with omics data288
Loss of yeast peroxiredoxin Tsa1p induces genome instability through activation of DNA damage checkpoint and elevation of dNTP levels65
Molecular pathogenesis of abnormal chondrocyte differentiation in a transgenic mouse model218
Identification of a functional variant in CHST3 associated with the susceptibility for lumbar disc degeneration143
Towards spinal cord repair: strategies to overcome the glial scar70
Prevalence and genotype of hepatitis G virus in Chinese professional blood donors and hepatitis patients81
BAF250a-containing complex is required for secondary heart field development57
Osteogenic behavior of alginate encapsulated bone marrow stromal cells: An in vitro study153
Visualizing becterial proteomes52
Protective effects of Chinese Medicine salvianolic acid B, astragaloside IV, and daillyl trisulfide on endothelial cells against damage induced by H2O267
A functional variation in CD55 increases the severity of 2009 pandemic H1N1 influenza A virus infection117
BIPES, a cost-effective high-throughput method for assessing microbial diversity94
Postnatal glutamatergic and GABAergic transmission within the vestibular nucleus is critical for the maturation of canal-related spatial map1219
Terminable cell-based GDNF delivery device for intravitreal applications91
DNA Aptamer selection and cellular delivery for the inhibition of E3 Ubiquitin Ligase WWP1122
Modifications in perineuronal nets within the rat vestibular nuclei during postnatal development and in injury61
The Interplay between MT1-MMP and ADAMs in Vascular Development92
Correlation between compositional and mechanical properties of human mesenchymal stem cell-collagen microspheres during chondrogenic differentiation109
Regulation of Foxmic By the RAF/MEK/MAPK Pathway53
Genomic organization of the human procollagen α1(II) collagen gene61
Wnt signaling gradients establish planar cell polarity by inducing Vangl2 phosphorylation through Ror21059
Inhibitor of apoptosis proteins and ovarian dysfunction in galactosemic rats98
Aligned chitosan nanofibers for culturing Schwann cells to guide axonal growth54
Spatiotemporal expression of chondroitin 6-sulfotransferase (C6ST) in regeneration of crush-injured sciatic nerves of adult rats62
Sir2 deletion prevents lifespan extension in 32 long-lived mutants132
Mental and physical activities delay cognitive decline in older persons with dementia179
Development of heparin and heparan sulfate from recombinant syndecan-1 as a potential therapeutic for bronchiectasis63
Genetic analyses of matrix protein function and terminal differentiation of hypertrophic chondrocytes66
In vivo study of asporin polymorphic variants in chondrogenesis and degenerative skeletal diseases72
Recombinant expression and characterization of chondroitinse ABC I and II52
Enrichment of committed, chondroitin sulfate-expressing human nucleus pulposus cells over progenitors under alginate encapsulation68
An in-vitro and surface chemical analysis of nickel-titanium alloys enhanced by plasma ion implantations surface treatment62
The association of osteoprotegerin gene polymorphism with knee osteoarthritis in Chinese population82
EpiRegNet: constructing epigenetic regulatory network from high throughput gene expression data for humans51
Towards the understanding of nickel trafficking in helicobacter pylori: expression and brief characterization of a his-rich protein63
In vitro generation of Schwann cells from mammalian skin for bridging injured nerves99
Nucleic acid aptamers against aggrecanases: a novel method for Degenerative Disc Disease Therapy43
Aggrecanase expression, refolding, puriffication and characterization as a foundation for tailored differential SELEX65
Microvesicles secreted by macrophages shuttle invasion-potentiating microRNAs into breast cancer cells115
CLUSTAG: Hierarchical clustering and graph methods for selecting tag SNPs160
MEKK1-induced phosphorylation and activation of TORC1 transcriptional coactivator50
Synergistically interferon-g enhances paclitaxel-induced nitric oxide production in a murine alveolar macrophage cell line: roles of NF-kB, MEK and PKCd59
Identification of FAM96B as a novel prelamin A binding partner68
Roles of a novel splice variant of human IFI16 in innate immune response53
A study of Epstein-Barr virus-encoded small regulatory RNAs234
Three-dimensional culture of bovine nucleus pulposus cells in protein matrices56
Chondroitin sulfates restrict axonal growth along the projection path of vestibular nuclear (VN) neurons across the hindbrain of prenatal rats82
A study of apoptosis in a human epithelial tumour cell line212
Disrupted expression of matrix genes in the growth plate of the mouse cartilage matrix deficiency (cmd) mutant57
Translation of type II procollagen mRNA and hydroxylation of the cell-free product80
A commentary on phylogenetic analysis of H5N1 influenza A viruses72
Phospho-Regulated Interaction between Kinesin-6 Klp9p and Microtubule Bundler Ase1p Promotes Spindle Elongation83
A human suppressor of c-Jun N-terminal kinase 1 activation by tumor necrosis factor α98
Analysis of mouse Hox-2 gene regulation by transgenic mice54
A type III collagen Gly559 to arg helix mutation in Ehler's danlos syndrome type IV67
Localization and the release mechanism of secretin in hypothalamo-pituitary system of the Wistar Rat Rattus novegicus59
Yeast TRAMP complex facilitates splicing factor recruitment and contributes to optimal slicing efficiency60
TTF-1 and RET promoter SNPs: Regulation of RET transcription in Hirschsprung's disease165
Mild iodine deficiency and thyroid disorders in Hong Kong.119
Sox2 is Required for Sensory Organ Development in the Mammalian Inner Ear62
Abnormal regulation of cartilage and bone growth in transgenic mice expressing mutant collagen X73
Molecular dynamics simulations of LysRS: An asymmetric state80
Functional variants in the promoter region of Chitinase 3-like 1 (CHI3L1) and susceptibility to schizophrenia1326
Reduced neuronal nitric oxide production in KIF5b-deficiency mice72
Requirement for tax-induced recruitment of TORC family coactivators in transcriptional activation59
External fixation fracture model of the mouse femur53
EpiRegNet: constructing epigenetic regulatory network from high throughput gene expression data for humans96
Expression of mutated HPN - a nickel binding protein from helicobacter pylori102
The biochemical mechanism of hypoxia-induced mobilization of glycogen in cultured cancer cell98
Bioinformatic application in proteomic research on biomarker discovery and drug target validation61
Epidermal growth factor induces Gadd45 (growth arrest and DNA damage inducible protein) expression in A431 cells115
In vivo chondrocytic differentiation of the allogenic stem cells in the murine intervertebral disc94
Aged-related degeneration of lumbar intervertebral discs in rabbits revealed by deuterium oxide-assisted MRI81
Heparan sulfates that upregulate regeneration of psot-traumatic sciatic nerves of adult guinea pigs48
ER stress in the pathogenesis of osteochondrodysplasia203
Lack of β1 integrin results in defective notochord morphogenesis with impaired convergent extension in the mouse113
Co-evolution of transcription factor and its binding sites76
Understanding the Basis of Genetic Studies: Adolescent Idiopathic Scoliosis as an Example99
An α1(II) Gly913 to Cys substitution prevents the matrix incorporation of type II collagen which is replaced with type I and III collagens in cartilage from a patient with hypochondrogenesis107
Sox2 regulates hair type specification and hair cycle84
Differential roles of perineuronal net components in functional modifications of rat vestibular nuclear neurons49
Rabbit bone marrow derived mesenchymal stem cells induced collagen gel contraction-fabrication of tissue-like structures with different cell densities88
Biological resurfacing for full thickness articular bone-cartilage defect: the use of free periosteal graft, porous metal mould and continuous passive motion in a rabbit model110
Expression of chondroitin sulfotransfgerases in relation to cranial motor neuron migration48
Modulation of cyclin expression by over-expression of the forkhead boxtranscription factor FoxM1182
Human Ocular Epithelial Cells Endogenously Expressing SOX2 and OCT4 Yield High Efficiency of Pluripotency Reprogramming110
Nano Structure and Biomechanics of Human Intervertebral Disc Collagens69
Protein Expression Profiles of the Intervertebral Disc57
Genetic study of a large Chinese amyotrophic lateral sclerosis family79
Divergent subcellular locations of HTLV-I tax and Int-6: A contrast between in vitro protein-protein binding and intracellular protein colocalization98
Neurotrophin receptor immunostaining in the vestibular nuclei of rats115
Genetics of Lumbar Disk Degeneration: Technology, Study Designs, and Risk Factors101
Intracellular Reactive Oxygen Species enhances the survival of cells under the conditions of ER stress57
b-Chemokine Polymorphisms are not Associated with Tuberculosis in the Hong Kong Chinese Population84
An Emerging Role of Notch Signaling in the Switch to Fate Commitment of Bone Marrow-Derived Schwann Cells53
Viral modulation of cellular signaling through SARS coronavirus structural proteins47
Role of p53/p63 in chondrocyte re-differentiation upon activation of ER stress60
Role of membrane Type-I matrix metalloproteinase (MT1-MMP) in mouse intestinal development45
Cholesterol-induced mammary tumorigenesis is enhanced by adiponectin deficiency: role of LDL receptor upregulation54
MOOCs in Postmodern Asia - Session: Technology-accelerated Learning in the West28
Genetic association studies in lumbar disc degeneration: a systematic review46
Virtually there: a journey to the HKU Medicine Island for teaching and learning71
Prelamin A Regulates DNA Repair and Senescence via Histone Modifications46
In silico mapping of quantitative trait loci affecting bone mineral density in mice64
The role of Sox10 in enteric neural crest cell migration113
Purification and targeting sclerostin: steps towards, osteoporosis therapy59
Lumbar disc degeneration is linked to a carbohydrate sulfotransferase 3 variant.181
Inositol 1:2(cyclic),4,5-trisphosphate is not a major product of inositol phospholipid metabolism in vasopressin-stimulated WRK1 cells.73
Sufu controls the number and cell fate of hindbrain progenitors72
Reduction of cell proliferation in human colon cancer cell line by hexamethylene bisacetamide (HMBA)57
Molecular cloning and characterization of chondroitin 6-sulfotransferase (c6st) in crush-injured rat sciatic nerves75
The association of lumbar intervertebral disc degeneration on magnetic resonance imaging with body mass index in overweight and obese adults: a population-based study107
Upregulation of NF-kB signaling pathway in hepatocellular carcinoma68
A study on the association of the chromosome 12p13 locus with sporadic late-onset alzheimer's disease in Chinese87
SNP-SNP interaction in intervertebral disc disease with genes in the Aggrecan Degradation Pathway80
The regeneration of transected sciatic nerves of adult rats using chitosan nerve conduits seeded with bone marrow stromal cell-derived Schwann cells149
Engineering a portable riboswitch-LacP hybrid device for two-way gene regulation126
Topography of inferior olivary neurons that encode canal and otolith inputs66
Investigation of PTPN21 in ErbBs signaling transduction and its potential biological function123
Post-transcriptional suppression of gene expression in Xenopus embryos by small interfering RNA88
PKC(delta)-dependent de-ubiquination and stabilisation of Gadd45 in A431 cells over-exposed to EGF95
Studies on polyphosphate kinase 2 mechanism and inorganic polyphosphate function346
Functional replication of the tendon tissue microenvironment by a bioimprinted substrate and the support of tenocytic differentiation of mesenchymal stem cells127
Viral suppression of type I interferon production through PACT targeting39
The molecular bases underlying the inner ear phenotypes of mouse mutants, yellow submarine (YSB)and light coat and circling (LCC)76
(iii) Whole-genome association studies of complex diseases179
MMP14 regulates the lineage progression of hypertrophic chondrocytes80
The expression of chondroitin sulfates in rat embryonic hindbrain and their roles on the lateral migration of trigeminal motor neurons48
Understanding the biological role of UHRF137
Combinatorial use of offline SCX and online RP-RP liquid chromatography for iTRAQ-based quantitative proteomics applications228
Role of IHH signaling in the progression of joint formation in digit development60
Genome-wide Haplotype Association Mapping (HAM) in mice leads to an identification of a genetic variant in CER1 associated with bone mineral density in premenopausal women79
Prelamin A Induces Cellular Senescence by Activating Heterochromatin Formation53
Dysregulation of Aqp3 and endolymphatic hydrops in a mouse model of campomelic dysplasia68
Predicting the spatiotemporal dynamics of hair follicle patterns in the developing mouse100
The use of aptamer‐conjugated nanoparticles in novel malaria diagnosis platforms61
Ectopic expression of unfolded mutant collagen X in bone cells results in generalised hyperostosis in mice61
Quantitation of type I and III collagens using electrophoresis of alpha chains and cyanogen bromide peptides95
A study of the biological effect of Epstein-Barr virus encoded latent membrane protein 1 (LMP1) in human epithelial cells190
P21-activated protein kinase is overexpressed in hepatocellular carcinoma and enhances cancer metastasis involving c-Jun NH2-terminal kinase activation and paxillin phosphorylation146
Changes in sensitivity of muscle to calcium as a result of chronic morphinization179
Comprehensive Analysis of MRI-Phenotypes Provides New Insights into Lumbar Disc Degeneration for Genetic Studies91
Mcp1p tracks microtubule plus ends to destabilize microtubules at cell tips87
Analysis of craniofacial defects in Six1/Eya1-associated Branchio-Oto-Renal Syndrome72
Localization of murine embryonic stem cells at the area of myocardial infarction in mice heart50
Reconstruction of the mouse Hoxb-3 gene expression pattern in transgenic mice64
Characterization of human and mouse peroxiredoxin IV: Evidence for inhibition by Prx-IV of epidermal growth factor- and p53-induced reactive oxygen species121
Functional analysis of SOX10 mutations identified in patients with Waardenburg-Hirschprung Syndrome75
Targeted inactivation of Kinesin-1 in pancreatic β-cells in vivo leads to insulin secretory deficiency84
Human T-cell leukemia virus type I oncoprotein tax targets the centrosome69
Dedifferentiation: A new approach in stem cell research93
Apoptosis of human gastric adenocarcinoma cells induced by β-ionone115
G-quadruplex DNA aptamers and their ligands: Structure, function and application121
Diltiazem co-treatment in renal transplant patients receiving microemulsion cyclosporin109
Ex vivo generation of myelinating Schwann-cell-like cells from bone marrow-derived neurospheres71
Expression of a kallikrein-like protein in prostatic intraepithelial neoplasia in ventral prostate of the noble rat166
Differential Regulation of FoxM1 Isoforms by Raf/MEK/ERK Signaling46
A study of glucose-6-phosphate dehydrogenase (G6PD)class I deficient mutants: R393G and R393H at the dimerinterface versus other mutants195
Genes and Diseases: Basic Concepts59
New approaches for therapeutic aptamer selection and delivery52
Hypertrophic chondrocytes contribute directly to the osteoblast and osteocyte lineage in endochondral bones in vivo100
Kinetics and synergistic effects of siRNAs targeting structural and replicase genes of SARS-associated coronavirus132
Requirement of N-linked glycosylation in the luminal domain for optimal proteolytic activation of liver-enriched transcription factor CREB-H65
Gli-mediated regulation of Sox9 in limb development62
An integrated metalloproteomic analysis depicts the proteomic features of Helicobacter pylori in response to Bi(III)75
Molecular signaling by ganglioside-modulated protein phosphorylation systems53
Sufu and Gli3 repressor mediate the temporal basal-to-apical progression of hair cell differentiation in mammalian cochleae57
Modifications in perineuronal nets of rat vestibular nuclear neurons during postnatal development and in injury59
Genetic and Epigenetic Alterations of DLC-1 Gene in Hepatocellular Carcinoma122
Thalassospira xiamenensis sp. nov. and Thalassospira profundimaris sp. nov95
Prevalence of intervertebral disc degeneration: a MRI study of 769 volunteers85
The role of extracellular matrix in planarian regeneration360
Codon usage bias and the evolution of influenza A viruses. Codon Usage Biases of Influenza Virus126
Decreased c-Jun expression correlates with impaired spinal motoneuron regeneration in aged mice following sciatic nerve crush151
N-methyl-D-Aspartate receptor blockade-mediated apoptosis induced GSK activation and increase of TAU phosphorylation in newborn rats92
Genetics of aging, progeria and lamin disorders77
Increased release of heparan sulfate proteoglycans from a human colon cancer cell line treated with hexamethylene bisacetamide52
Eya1 regulates notch signaling in branchial epithelium during craniofacial development65
Characterization of human mesenchymal stem cells selected by collagen barrier69
Study of the function of Kinesin-1 (KIF5B) in long bone development203
Uncovering functions of long-chain polyphosphate in higher eukaryotes: storage and synthesis of polyphosphate in matrix vesicles during mineralization32
The role of reactive oxygen species in UPR-mediated cell death49
Synaptic dysfunction implicated in leucine-rich repeat kinase-2 (LRRK2) R1441G knockin mice121
Hepatocyte-specific activation of NF-κB does not aggravate chemical hepatocarcinogenesis in transgenic mice130
MT1-MMP regulates Notch signalling to maintain B lymphocyte development46
Psr1p interacts with SUN/sad1p and EB1/mal3p to establish the bipolar spindle 38
The molecular and cellular changes underlying increased bone formation in a mouse model with generalized progressive hyperostosis51
The Identification of Regulatory Element(s) in the Promoter of the Thioredoxin Reductase gene52
Chondrocytes from the endplate cartilage contribute to the inner annulus fibrosus in normal and degenerative intervertebral disc62
Association of the Asporin D14 Allele with Lumbar-Disc Degeneration in Asians196
The coactivator Bridge-1 increases transcriptional activation by pancreas duodenum homeobox-1 (PDX-1)106
The molecular and cellular changes underlying increased bone formation in a mouse model with generalized progressive hyperostosis59
ERO1-β, a pancreas-specific disulfide oxidase, promotes insulin biogenesis and glucose homeostasis55
Lethal osteogenesis imperfecta congenita and a 300 base pair gene deletion for an α1(I)-like collagen67
MT1-MMP cleaves Dll1 to negatively regulate Notch signalling to maintain normal B-cell development175
Heparanase 1 and Heparanase 2 expression in Hippocampal Neurons37
SWI/SNF protein component BAF250a regulates cardiac progenitor cell differentiation by modulating chromatin accessibility during second heart field development112
The restrictive role of chondroitin sulfate moieties on the lateral migration of trigeminal motor neurons during hindbrain development in rats102
A COL2A1 mutation in achondrogenesis type II results in the replacement of type II collagen by type I and III collagens in cartilage82
Cell-specific expression of Cre recombinase in Purkinje and retinal bipolar neurons68
Chasing Ehrlich’s Magic Bullet – Nucleic acid aptamers for therapy and diagnostics24
Two new rat α-globin sequences as identified by the conserved region PCR93
Heparan sulfate/syndecan-1 modulates the balance between proteinase and anti-proteinase in bronchiectasis67
Exploring the mutations at the C-terminus of human G6PD52
The regulatory role of perineuronal nets and semaphorin 3A in the developmental maturation of the central vestibular circuitry55
Building creative and collaborative assessment strategies into a large introductory biomedical sciences class - evidence for sustained deep learning and potential adaptability for MOOCs35
Regulation of GADD153 Expression at Post-transcriptional Level by ROS57
Investigation into the interactions between diadenosine 5′,5‴-P1,P4-tetraphosphate and two proteins: Molecular chaperone GroEL and cAMP receptor protein85
Decellularization of chondrocyte-encapsulated collagen microspheres64
The developmental roles of the extracellular matrix: Beyond structure to regulation155
Ubiquitination and proteosome dependent degradation of the activated form of human liver-enriched transcription factor CREB- H39
Expression of engrailed-Hoxb5 transcriptional repressor by Wnt1-Cre produces neurocristopathies of pigmentation and enteric nervous system defects in mice74
Small-molecule suppressors of proteoglycan catabolism in degenerative disc cells32
Expression of the mouse α1(II) collagen gene is not restricted to cartilage during development65
Postnatal maturation of the vestibular circuit for gravity detection is regulated by perineuronal semaphorin 3A and chondroitin sulfates51
Generation of mouse notochord cell lines for the study of notochord function during intervertebral disc development108
Cardiomyopathy associated with microcirculation dysfunction in laminin α4 chain-deficient mice90
Nesprin-2 giant safeguards nuclear envelope architecture in LMNA S143F progeria cells100
Separation and characterization of urinary glycosaminoglycans of kidney stone formers and normal individuals45
Mechanism underlying fate commitment of human bone marrow stromal cells to Schwann cells50
Raf/MEK/MAPK signaling stimulates the nuclear translocation and transactivating activity of FOXM1.73
The adamantane-derived bananins are potent inhibitors of the helicase activities and replication of SARS coronavirus196
Mapping of a genetic modifier of congenital heart defect in type IIA procollagen deficient mice59
A study of anti-mitogenic mechanism of epidermal growth factor182
FoxM1c counteracts oxidative stress-induced senescence and stimulates Bmi-1 expression111
Linkage analysis with subsequent fine-mapping on familial early-onset degenerative disc disease80
Development of nucleic acid aptamers against Plasmodium falciparum lactate dehydrogenase for improving the diagnosis of malaria95
Tumor Suppressive Functions of Krüppel-like Factor 4 (KLF4) in Neuroblastoma63
Derivation of clinically applicable schwann cells from bone marrow stromal cells for neural repair and regeneration129
Sox10 is required for proliferation and migration of enteric neural crest stem cells77
Overexpression of eIF-5A2 in mice causes accelerated organismal aging by increasing chromosome instability109
In vivo study of Asporin, a genetic risk factor associated with degenerative disc diseases82
Effects of oligosaccharide products on activity of chondroitin sulphate ABC lyase I – Towards improving the efficacy of the enzyme for in vivo treatment65
Comprehensive analysis of collagen metabolism in vitro using [43H]/[14C]proline dual-labeling and polyacrylamide gel electrophoresis87
Identification of novel interactions between viral envelop proteins and activating receptor family of natural killer cells112
Genetic and genomic analyses of chondrocyte adaptation to ER stress in vivo76
Semaphorin3A, associated with perineuronal nets, regulates the development of the maturation of the central vestibular circuitry42
Characterisation of steroidogenic acute regulatory protein related lipid transfer domain (START)domain in deleted in Liver Cancer 2(DLC-2)125
Towards an understanding of global gene expression changes in hypertrophic chondrocytes undergoing ER stress61
TLR ligand-induced podosome disassembly in dendritic cells is ADAM17 dependent86
Further analysis of the nicastrin: presenilin complex”94
Yeast pre-mRNA splicing is facilitated by a RNA surveillance complex87
Further evidence that the failure to cleave the aminopropeptide of type I procollagen is the cause of Ehlers-Danlos syndrome type VII114
DNA origami integrated to aptamer-mediated molecular recognition64
Surfactant protein B gene polymorphism is associated with severe influenza.101
Extensive alternative splicing within the amino-propeptide coding domain of α2(XI) procollagen mRNAs: Expression of transcripts encoding truncated pro-α chains129
Hippocampal metabolomics using ultrahigh-resolution mass spectrometry reveals neuroinflammation from Alzheimer’s disease in CRND8 mice.66
Isthmin, a novel extracellular regulator in nodal signaling pathway236
FaSD: a efficient model to detect SNPs for NGS data61
Adiponectin as a key player of inflammation156
Glycosaminoglycans elaborated by astrocytes in serum-containing culture55
Neurotrophins - Players in the regulation of neuronal survival and apoptosis71
Can stem cells home to the injured intervertebral disc via intravenous infusion? A murine model68
Activation of Ras-dependent Elk-1 activity by MLL-AF4 family fusion oncoproteins147
Erratum: Molecular genetic dissection of mouse unconventional myosin- VA: Tail region mutations (Genetics (April 1998) 148 (1963-1972))79
Inhibition of E3 ubiquitin ligase WWP1 with selective DNA Aptamers64
Type IIA Procollagen: A Positive Regulator of Nodal Signaling During Early Vertebrate Embryogenesis63
Rapid fractionation of collagen chains and peptides by high-performance liquid chromatography99
Fate and properties of notochordal descendent cells in the intervertebral disc: implicationto disc degeneration79
Purification and identification of sclerostin interacting partners: steps towards therapy with aptamer-based inhibitors58
Inhibition of HBV gene expression and replication by stably expressed interferon-α1 via adeno-associated viral vectors113
Vitamin D Inhibits COX-2 Expression and Inflammatory Response by Targeting Thioesterase Superfamily Member 4118
Essentials of chemical biology: Structure and dynamics of biological macromolecules110
Diadenosine polyphosphate cellomics: Characterising proteins in prokaryotic stress that evolve and involve diadenosine polyphosphates.58
Collagen II is essential for the removal of the notochord and the formation of intervertebral discs105
Axon routing at the optic chiasm after enzymatic removal of chondroitin sulfate in mouse embryos83
The TATA-containing core promoter of the type II collagen gene (COL2A1) is the target of interferon-γ-mediated inhibition in human chondrocytes: Requirement for Stat1α, Jak1 and Jak2109
Chromatin remodelling regulated by nuclear lamins in DNA repair and accelerated aging36
Changes in perineuronal nets within the rat vestibular nuclei during postnatal development and in injury67
Mechanistic insight into point mutations in sedlin that result in spondyloepiphyseal dysplasia tarda60
The isolation and purification of alkaloids from Melodinussuaveolens (Apocynaceae) and their effects on tissues and enzymesystems219
Genome-wide association study of Degenerative Disc Disease (DDD)101
Neutrophil-mediated degradation of lung proteoglycans: Stimulation by tumor necrosis factor-α in sputum of patients with bronchiectasis78
Endoplasmic reticulum-mediated quality control of type I collagen production by cells from osteogenesis imperfecta patients with mutations in the proα1(I) chain carboxyl-terminal propeptide which impair subunit assembly97
Correlation between the nano-structure and the macro-mechanics of the human intervertebral discs72
Involvement of perineuronal nets in developmental plasticity of the central vestibular system59
A preliminary study for development of oral vaccines for poultry and wild birds against avian H5N1 influenza virus infection63
Cell quantity and degenerative stage dependent effect of allogeneic mesenchymal stem cells on regeneration of intervertebral disc72
Perineuronal net regulates synaptic plasticity of central circuitry63
Molecular basis for increased bone formation in a mouse expressing mutant type X collagen71
The disaccharide composition of heparan sulfates that upregulate regenetation of post-traumatic sciatic nerves of adult guinea pigs45
Post-activation turn-off of NF-κB-dependent transcription is regulated by acetylation of p65124
Mice null for brush border myosin I assemble brush borders and lack an overt phenotype59
A novel genome-wide full-length kinesin prediction analysis reveals additional mammalian kinesins71
Identification of a potential auto-regulatory site upstream of the mouse Hoxb-3 gene52
Heparin fragments as a potential therapeutic for bronchiectasis and chronic obstructive pulmonary disease58
Investigating the role of FOXM1 in the maintenance of human embryonic stem cell pluripotency135
Transgenic mice expressing human epidermal growth factor show stunted growth41
Epigenetic control of DNA repair in premature ageing53
A simple and sensitive HPLC procedure for the quantitation of lamotrigine in plasma54
Double stranded RNA-binding protein PACT counteracted by viruses is a cellular partner and activator of RIG-I and MDA5 in innate antiviral response44
The dual role of combinatorial chondoritinase in overcoming the chondroitin sulfate barrier95
-459C>T point mutation in 5′ non-coding region of human GJB1 gene is linked to X-linked Charcot-Marie-Tooth neuropathy207
Activity assays of Chondroitinase ABCI immobilized on chitosan beads95
Novel post transcriptional modification of UHRF1 and its biological relevance39
Fate of Mesenchymal Stem Cells Injected Into Intervertebral Discs56
Genetic variant representation, annotation and prioritization in the post-GWAS era102
Glycosaminoglycan composition in the regenerative environment of the sciatic nerve of adult hamsters82
Analysis of the butyrylcholinesterase gene and nearby chromosome 3 markers in Alzheimer disease89
Electrophoretic studies on matrix vesicles from rabbit growth plate cartilage200
Heparanase modulates synaptic plasticity at the hippocampus75
An essential role for type IIA procollagen in heart development51
Overcoming the chondroitin sulphate barrier in injured nerve: the efficacy of chondroitinase ABC treatment and the potency of disaccharide products113
Auto/cross-regulation of Hoxb3 expression in posterior hindbrain and spinal cord112
Sox10 mutation affects inner ear gliogenesis and morphogenesis73
Bone Fracture Healing in Laminopathy-based Premature Aging75
Epstein–Barr Virus and Innate Immunity: Friends or Foes?6
Expression of chondroitin 6-sulfotransferase mRNA and the sulfation product in post-crush sciatic nerves of adult rats55
Surface mechanical properties, corrosion resistance, and cytocompatibility of nitrogen plasma-implanted nickel-titanium alloys: A comparative study with commonly used medical grade materials125
Uncoupled endochondral ossification in transgenic mice expressing type X collagen with mutations in the NC1 domain78
Changes in Perineuronal Nets within the Rat Vestibular Nuclei during Postnatal Development and in Injury70
Suppression of innate antiviral response by severe acute respiratory syndrome coronavirus M protein is mediated through the first transmembrane domain72
Endocannabinoid regulates developmental plasticity of central vestibular synapses and vestibular behaviors in rats50
Aptamer-based piezoelectric quartz crystal biosensor for SARS coronavirus helicase51
Oriented Schwann Cells Culture on Aligned Chitosan Nanofibers for Axonal Growth Guidance40
Comparative analysis of the activation of unfolded protein response by spike proteins of severe acute respiratory syndrome coronavirus and human coronavirus HKU158
Synaptojanin, an inositol phosphatase, is a target for three different MLL fusion partners71
Hypertrophic chondrocytes can become osteoblasts and osteocytes in endochondral bone formation173
crm-1 facilitates BMP signaling to control body size in Caenorhabditis elegans115
A proteomics study to reveal the molecular response to protein misfolding in chondrocytes210
Towards intracellular aptamers: delivery of anti-SCV helicase aptamers and development of aptamers againstSATB1523
The impact of Hoxb3 mutation on plasmacytoma74
Evidence for direct and specific physical interaction between the stress-inducible CHOP mRNA and intracellular proteins50
SPS: a simulation tool for calculating power of set-based genetic association tests79
Exploring the molecular identity of Ganglioside-stimulated protein kinase191
The mitogen-activated protein kinase pathway promotes mitotic progression through the forkhead box transcription factor foxmi63
Genome-wide association study of Degenerative Disc Disease (DDD)96
Immunostimulatory function of the defective interfering RNA of Measles virus49
Over-expression of epidermal growth factor precursor in vitro and in vivo76
Perturbation of Hoxb5 Signaling in Vagal Neural Crests Down-Regulates Ret Leading to Intestinal Hypoganglionosis in Mice135
Tissue-specific and differential expression of alternatively spliced α1(II) collagen mRNAs in early human embryos151
The Wnt coreceptor Ryk regulates Wnt/planar cell polarity by modulating the degradation of the core planar cell polarity component Vangl21065
Endophilin B1 as a novel regulator of nerve growth factor/TrkA trafficking and neurite outgrowth144
Context dependent impact of Sox9 campomelic dysplasia mutation53
Unfolded protein response leading to cataractogenesis in a microphthalmia cataract mouse mutant89
Erratum: Evaluation of next-generation sequencing software in mapping and assembly75
Heparanase expression in Schwann cells as revealed in injured sciatic nerves and dorsal root ganglion explant culture75
The functions of suppressor of fused (Sufu) in midbrain and hindbrain neurogenesis186
The two PPX-GppA homologues from Mycobacterium tuberculosis have distinct biochemical activities126
UHRF1 in Hedgehog signalling and basal cell carcinoma43
G6PDdb, an integrated database of glucose-6-phosphate dehydrogenase (G6PD) mutations65
Genome-wide association study of Degenerative Disc Disease (DDD)97
Enhanced corrosion resistance and biocompatibility by plasma implantation of nickel titanium alloys: an in vitro and surface chemical study69
Analysis of craniofacial defects in Six1/Eya1-associated Branchio-Oto-Renal Syndrome1451
Regulation of the mouse hoxb-3 gene in the neural expression domains during embryogenesis175
Probing the mechanistic basis of the bacteriophage lambda-encoded recombination system in E. Coli63
New Bone Formation by Injected With Osteogenic Cells Confined in Sodium Alginate Microcapsules73
Transcriptional profiling of enteric neural crest cells65
Inhibiting the integrated stress response pathway prevents aberrant chondrocyte differentiation thereby alleviating chondrodysplasia74
In vitro chondrogenic differentiation of human mesenchymal stem cells in collagen microspheres: Influence of cell seeding density and collagen concentration132
sPDZD2, a novel modulator in Hedgehog signaling73
Demonstration of specific physical interaction between CHOP mRNA and intracellular proteins215
Visualizing the Proteome Escherichia coli by Recombineering Technology53
Rational design and development of small interfering RNAs and small hairpin RNAs for inhibition of hepatitis C virus replication55
Prediction of lumbar spinal stenosis in Chinese: findings from a genome-wide association study84
Degradation of lung matrix proteoglycans in bronchiectasis78
Composition and functional studies of chondroitin sulfate proteoglycans at borders between astrocytes and Schwann cells inrelation to axonal crossing173
Generation of early HIV-1 specific intermediated B cell line based on improved B cells immortalization followed with magnetic isolation from PBMC of a health donor44
Function genomics and transgenic technology: lessons learnt from manipulating the mouse genome42
Migration of mesenchymal stem cells to injured spinal cord through interaction of SDF-1/ CXCR4122
Reactive oxygen species (ROS) regulates the expression of the growth-arrest-and DNA-damage inducible gene at the post-transcriptional level59
Derivation of oligodendrocyte precursor cells from adult bone marrow stromal cells318
Gene elav of Drosophila melanogaster: A prototype for neuronal-specific RNA binding protein gene family that is conserved in flies and humans100
Understanding the contribution of Lgr5+ interzone progenitor cells in articular cartilage regeneration54
Kinetic studies of imidazole and its methyl derivative binding to metmyoglobin: Effects of substitute methyl on the binding affinity89
An insertional mutation causing deafness and affecting the regulation of pigmentation in mice65
Chondroitin sulfate moieties control motor neuron migration in the rat embryonic hindbrain63
Immunostimulatory function of the defective interfering RNA of Sendai virus279
SET domain protein lysine methyltransferases: Structure, specificity and catalysis94
Assessing clusters and motifs from gene expression data104
Cross-regulation in the mouse HoxB complex: The expression of Hoxb2 in rhombomere 4 is regulated by Hoxb1111
Nuclear localization of the cell cycle regulator CDH1 and its regulation by phosphorylation111
Antagonistic spindle motors and MAPs regulate metaphase spindle length and chromosome segregation110
Overexpression of Hoxb3 affects inner ear neurogenesis56
Influenza A virus NS1 protein does not suppress RNA interference in mammalian cells101
4-O-sulfated Chondroitins Contribute to Axon-restrictive Property in Schwann cell-as-trocyte Encounters112
Hypertrophic chondrocytes under ER stress utilizes the hypoxia stress signals for survival44
Sign epistasis limits evolutionary trade-offs at the confluence of single- and multi-carbon metabolism in Methylobacterium extorquens AM155
Directed differentiation of bone marrow stromal cells to fate commitment of Schwann cells for remyelination therapy62
Anti-proliferative effects of PDZD2 and its secreted protein sPDZD2 on prostate cancer cells73
Roles of Kinesin-1 mediated intracellular transport in skeletal development59
A reproducible radiological assessment score for fracture healing in mice63
Heparanase activity enhances MMP-7 dependent syndecan-1 shedding in the airway59
EYA1's conformation-specificity in dephosphorylating phosphothreonine in Myc and its activity on Myc stabilization in breast cancer88
Lack of beta1 integrin results in hemivertebrae development in mice65
The role of Uhrf1 in development and tumorigenesis165
Activation of the cyclin B1 promoter by FOXM1 is stimulated by the mitogen-activated protein kinase pathway72
Abnormal compartmentalization of cartilage matrix components in mice lacking collagen X: Implications for function122
Mechanistic study of salmonella-induced reduction of cancer metastasis56
The role of SoxE transcription factors in melanoma development57
Sox proteins and inner ear development61
Suppression of HTLV-1 transcription by SIRT1 deacetylase99
Alleviating ER stress in chondrocytes: molecular strategies and the developmental cost of recovery48
The identification of enzyme activities that catalyse the reduction of immuoglobulin G interchain disulphides58
'Relax and repair' to restrain aging84
Perturbation of GABAergic synapses in the vestibular nucleus during a postnatal critical period impacts on the acquisition on spatial recognition70
Unraveling the role of type X collagen during fracture repair45
Interferon-genhances nitric oxide synthase expression induced by paclitaxel in alveolar macrophages: the roles of ras/mek/erk and NF-kB in signal transduction95
The role and imaging of PAX6 in a mouse model of alzheimer's disease64
Galactosemia and rat granulosa cell apoptosis76
Chondroitinase ABC enhances axonal regrowth through Schwann cell-seeded guidance channels after spinal cord injury.163
Dynamic changes of type II collagen in the degenerated murine discs71
Analysis of the sacral neural crest cell contribution to the hindgut enteric nervous system in the mouse embryo99
Impact of activating ADAMTS-5 in cartilage-related degenerative disorders63
Impact of extracellular inorganic polyphosphate on osteoblast proliferation, differentiation and apoptosis58
Expression of heparanase 1 and heparanase 2 at the hippocampus54
The Trp2 allele of Collagen IX is an age-dependent risk factor for the development and severity of intervertebral disc degeneration92
A biochemical study of thyrotoxic periodic paralysis234
Genetic association studies of lumbar disc degeneration (LDD)243
The zinc finger gene Krox20 regulates HoxB2 (Hox2.8) during hindbrain segmentation110
Overexpression of epidermal growth factor induced hypospermatogenesis in transgenic mice89
Interactions with p300 enhance transcriptional activation by the PDZ-domain coactivator Bridge-1120
Dual origin of osteoblasts in bone formation: terminally differentiated chondrocytes contribute to bone formation in vivo74
Assessment of aligner and SNP caller for next generation sequencing and a fast and accurate SNP detection method74
CMGRN: a web server for constructing multilevel gene regulatory networks using ChIP-seq and gene expression data238
Anti-apoptosis effects of Chinese herbal medicine salvianolic acid B (Sal B) on rat cerebral microvascular endothelial cells107
Characterization of three osteogenesis imperfecta collagen α1(I) glycine to serine mutations demonstrating a position-dependent gradient of phenotypic severity92
Identification of drug resistant mutations in HIV-1 CRF07_BC variants selected by nevirapine in vitro.52
Functional analyses of type IIA procollagen in embryo development218
p53 mediates autophagy activation and mitochondria dysfunction in kainic acid-induced excitotoxicity in primary striatal neurons69
The CRISPR/Cas9-mediated genome editing of Epstein-Barr virus: a new platform for genetic study33
Mammary gland-specific secretion of biologically active immunosuppressive agent cytotoxic-T-lymphocyte antigen 4 human immunoglobulin fusion protein (CTLA4Ig) in milk by transgenesis108
Regulation of CREB3L2 and FUS-CREB3L2 Transcriptional Activity Through Proteasome-dependent Degradation59
Role of Conserved Domains in the Transcriptional Function of Sox 10 In Vitro and In Ovo63
CREB3 subfamily transcription factors are not created equal: Recent insights from global analyses and animal models86
DNA aptamers that inhibit aggrecanase activity for degenerative disc disease and osteoarthritis therapy44
Distinct spatiotemporal expression of ISM1 during mouse and chick development62
Development of interfering RNA agents to inhibit SARS-associated coronavirus infection and replication.98
New avenues to malaria diagnosis – nucleic acid aptamers against P. falciparum histidine rich protein 2 and lactate dehydrogenase58
Understanding molecular mechanisms in mitochondria underlying LRRK2-related Parkinson’s disease95
PACT- and RIG-I-Dependent Activation of Type I Interferon Production by a Defective Interfering RNA Derived from Measles Virus Vaccine75
Cotranscriptional recruitment of yeast TRAMP complex to intronic sequences promotes optimal pre-mRNA splicing106
Roles of Epstein-Barr virus-encoded miR-BART microRNAs in viral infection of nasopharyngeal epithelial cells433
Mouse as a Model for Functional Genetic Studies58
Effects of Huanglian-Jie-Du-Tang and its modified formula on the modulation of amyloid-β precursor protein processing in Alzheimer's disease models.76
In vitro aptamer selection against the SARS Coronavirus Helicase52
Understanding the Function of Sedl gene and the Molecular Pathogenesis of spondyloepiphyseal Dysplasia Tarda63
The molecular consequences of Indian hedgehog mutations in distal digit patterning306
The antiproliferative effect of the kappa-specific opioid receptor agonist U50,488H does not correlate with the suppression of cyclic AMP and mobilisation of intracellular calcium80
Dosage-dependent requirement of Sedlin and Sedlin-like proteins in mouse yolk-sac visceral endoderm and embryo development60
The role of farnesyltransferase inhibitor in the treatment of Hutchinson Gilford progeria syndrome51
The role of endocannabinoid in long-term plasticity of vestibular GABAergic synapses and behavioral outcome in developing rats1168
Position and distance specificity are important determinants of cis-regulatory motifs in addition to evolutionary conservation75
A new role of anterograde motor Kif5b in facilitating large clathrin-coated vesicle mediated endocytosis via regulating clathrin uncoating14
Characterisation of MAD2B63
Glial cell line-derived neurotrophic factor family receptors are abnormally expressed in aganglionic bowel of a subpopulation of patients with Hirschsprung's disease110
Investigating the role of FoxM1 in cell cycle progression by inducibleRNA interference169
Deciphering the mechanisms of genetic disorders by high throughput genomic data235
Peptide analysis of collagen produced from cDNA by transcription and translation in vitro.86
In vivo study of asporin polymorphic variants in chondrogenesis and degenerative disc disease (DDD)205
Molecular and mutation analysis of hereditary multiple exostoses184
Functional characterization of an alkaline exonuclease and single strand annealing protein from the SXT genetic element of Vibrio cholerae114
Functional significance of the 3’-UTR in the mRNA of the stress-inducible protein CHOP/Gadd15346
CARP is a novel caspase recruitment domain containing pro-apoptotic protein98
The mechanism of cadmium removal from aqueous solution using non-metabolizing free cell of Aspergillus flavus 44-174
EPS8 and FOXM1 - Do they mesh to promote carcinogenesis?51
Exploring the mechanisms of salmonella-induced reduction of cancer metastasis88
In silico mapping of a charcot-marie-tooth disease gene in a pedigree of Hong Kong Chinese72
Natural occurrence and characterization of two internal ribosome entry site elements in a novel virus, canine picodicistrovirus, in the picornavirus-like superfamily133
Abnormal enteric nervous system development in a Sox10-NGFP mouse mutant107
Phylogenetic analysis of planarian collagens and their roles in regeneration87
An analysis of two naturally: occurring G6PD deficient mutants, G6PD Campinus and G6PD Fukaya158
Development of three-dimensional culture system for bovine nucleus pulposus cells68
Subcellular localization and post-translational modification of a novel PDZ-domain protein, PIN-1/PAPIN76
The relationship of p85 and the apoptotic signalling of N-(4-hydroxyphenyl)retinamide (4HPR)47
Herpes simplex virus type 1 Us11 protein inhibits type I interferon production by suppressing PACT mediated activation of RIG-I66
Integrating genetic linkage analysis and computational prioritzation in identifying host genetic factors response to influenza A virus infection55
Abnormal chondrocyte differentiation in COL2A1-SV40 T-antigen chimeric mice85
MIP-T3 is a novel inhibitor in TBK1/IRF3-dependent antiviral response75
The initial and subsequent inflammatory events during calcium oxalate lithiasis112
ERO1-β, a pancreas-specific disulfide oxidase, promotes insulin biogenesis and glucose homeostasis (The Journal of Cell Biology (2010) 188, 6 (821-832))44
Dissecting the genetics of complex trait in mouse: an attempt using public resources and in-houseknockout206
PACT, a double-stranded RNA binding protein, as cellular activator of cytoplasmic viral sensor MDA576
Viral suppression of innate antiviral response through PACT targeting24
The role of Sox2 and Sox18 in hair cycle and specification109
Group I p21-activated kinases are required for optimal activation of human T cell leukemia virus type 1 long terminal repeats by viral oncoprotein tax92
Over-expression of FoxM1 stimulates cyclin B1 expression128
Expression of vesicular glutamate transporters in peripheral vestibular structures and vestibular nuclear complex of rat141
Chondrocytes from the endplate cartilage contribute to the inner annulus fibrosus in normal and degenerative intervertebral disc46
Cleavage of spike protein of SARS coronavirus by protease factor Xa is associated with viral infectivity133
Effect of inorganic polyphosphate on higher eukaryotic cells61
Targeted Inactivation of KIF5B in Pancreatic β-Cells Leads to Insulin Secretory Deficiency and Increased β-Cell Mass in vivo57
Utility of Hoxb2 enhancer-mediated Cre activity for functional studies in the developing inner ear125
Dissecting gene function in the developing inner ear using HOXB2-CRE-mediated activity in transgenic mice78
Molecular and cellular aspects of plasticity after neural injury81
Isolation and characterization of a human collagen α 1(I)-like gene from a cosmid library72
Authors' Reply67
Kif5b is responsible for muscle development and normal function64
Sulfated maltoheptaose is a potential therapeutic in reducing neutrophilic inflammation in a cigarette smoke-induced rat model of chronic obstructive pulmonary disease65
Delivery of SCV helicase aptamers using cationic lipidic systems70
Lipid composition and lipases of Angiostrongylus cantonensis (nematoda: metastrongyloidea)215
Regulation of the tumour metastasis suppressor gene, NM23, by p21-activated protein kinase 570
A study of the physiological roles of proteoglycans in the inflammatory bronchial environment of patients with bronchiectasis210
Screening for PS1 mutations in a referral-based series of AD cases: 21 Novel mutations111
Cardiac developmental defects in a Hoxb mouse mutant Hoxb3lacZ57
Interaction of deleted in liver cancer 1 with Tensin2 in caveolae and implications in tumor suppression166
Roles of mitochondrial trafficking proteins in type-I interferon production66
Bismuth as an enzyme inhibitor: from antibacterium to antivirus89
Genomic analysis of the mutant locus in the novel transgenic mouse mutant, yellow submarine (ysb)84
ER-stress signaling and chondrocyte differentiation in mice78
Identification and characterization of the human type II collagen gene (COL2A1)74
Loss of peroxiredoxin Tsa1p induces genome instability through activation of DNA damage checkpoint and elevation of dNTP levels.48
Human erythrocyte membrane associated (Ca +Mg )-ATPase activator protein203
A 5' splice site mutation affecting the pre-mRNA splicing of two upstream exons in the collagen COL1A1 gene. Exon 8 skipping and altered definition of exon 7 generates truncated proα1(I) chains with a non-collagenous insertion destabilizing the triple helix156
FastPval: a fast and memory efficient program to calculate very low p-values from empirical distribution14
The induction of cellular stress responses by specific Kappa-opioid receptor agonist248
Indian hedgehog stimulates chondrocyte hypertrophic differentiation inendochondral bone formation166
Signal transduction of receptor-mediated antiproliferative action of melatonin on human prostate epithelial cells involves dual activation of Gα s and Gα q proteins99
Abnormal chondrocyte differentiation is dosage-dependent in transgenic mice expressing unassembled mutant collagen X in hypertrophic chondrocytes143
Reactive oxygen species stimulate phosphorylation of eIF2α independent of protein folding in ER-stressed cells55
Proteoglycans: From neural cell growth to regeneration61
A centrosomal target of human t-cell leukemia virus oncoprotein tax57
Notch Signaling in in vitro derivation of Schwann cells from bone marrow stromal cells156
Refining orthologue groups at the transcript level94
Resveratrol rescues adult stem cell decline and ameliorates progeroid features in Zmpste24 deficient mice46
Identification of the primary translation product of elastin mRNA77
Inhibition of XJ-160 virus replication by RNAi104
Isthmin, a novel extracellular regulator of nodal signaling68
Targeting unopposed neutrophil elastase in chronic respiratory inflammation with heparin oligosaccharides240
The role of Cell-matrix interactions mediated by β1 integrin in notochord development and function50
RecA protein-promoted homologous pairing between duplex molecules: Functional role of duplex regions of gapped duplex DNA63
Transgenic mice expressing human epidermal growth factor show stunted growth59
Structure of RPA32 bound to SMARCAL1 redefines the binding interface between RPA32 and its interacting proteins37
Derivation of oligodendrocyte precursors from bone marrow stromal cells: therapeutic potential and developmental origin64
The transcriptional control of trunk neural crest induction, survival, and delamination215
The vaccinia virus HindIII K fragment encodes a novel protein belonging to the serpin superfamily.111
A characterisation of the cellular toxicity induced by manganese75
Development of an aptamer-based biosensing system for measuring luteinizing hormone pulsatility for infertility treatment36
Differential effects of chondroitin and heparan sulfates on post-traumatic regrowth in sciatic nerves of adult guinea pigs48
Bioinformatics study of the lineage and tissue specificity of gene expression80
Molecular basis for growth plate abnormalities in a mouse model with schmid metaphyseal chondrodyplasia72
Lithium ion alters Ins(1,4,5)P3 production and mobilisation of intracellular free calcium in k-agonist stimulated rat ventricular myocytes73
An essential role for type IIA procollagen in mouse inner ear development57
Middle East respiratory syndrome coronavirus 4a protein is a double-stranded RNA-binding protein that suppresses PACT-induced activation of RIG-I and MDA5 in innate antiviral response85
Loss of MT1-MMP influences CNS development52
Comparative immunological evaluation of recombinant Salmonella typhimurium strains expressing model antigens as live oral vaccines229
Roles of human double-stranded RNA binding proteins TRBP and PACT in RNA interference277
Expression of the human COL2A1 gene in transgenic mice results in growth retardation79
Expression patterns of heparanase in normal and injured rat spinal cord67
Mesenchymal stromal cells rescue disc degeneration and function via suppression of fibrotic events88
Further study on the mechanism responsible for inhibition of cAMP production in CNE-2 and H9c2 cells upon k-opioid receptor stimulation50
Quantitative characterization of mouse embryonic stem cell self-renewal, differentiation and dedifferentiation57
Explant cultures of embryonic rat dorsal root ganglia exhibit heparanase expression in migrating cells84
N-terminus of desmin controls its retrograde transportation in differentiating myoblast cells97
Sputum sol in bronchiectasis stimulates IL-6 production from bronchial epithelial cells77
Regulatory role of Sox9 in chondrocyte hypertrophy59
Involvement of neuregulin 1 type III in the Ex Vivo generation of fate committed schwann cells from bone marrow stromal cells68
Group I p21-activated kinases facilitate Tax-mediated transcriptional activation of the human T-cell leukemia virus type 1 long terminal repeats77
Contents of fructose, citric acid, acid phosphatase, proteins and electrolytes in secretions of the accessory sex glands of the male golden hamster98
The sortilin-related recentor SORLA is functionally and genetically associated with Alzheimer Disease76
Effects of glycoproteins and glycosaminoglycans on the crystallization of urinary calcium oxalate55
Kreisler mediates the segmental expression of Hoxb-3 in the mouse hindbrain72
The liver-enriched transcription factor creb-H is a growth suppressor under-expressed in hepatocellular carcinoma58
MT1-MMP in craniofacial development and FGF signaling213
Identification and characterization of a novel interaction partner of centrosomal coiled-coil protein TAX1BP266
Fracture healing in collagen type X deficient mice: abnormalities in structure and mechanical properties of the fracture callus62
Receptor tyrosine kinase-like orphan receptor 2 (ROR2) and Indian hedgehog regulate digit outgrowth mediated by the phalanx-forming region131
Stabilization of PML nuclear localization by conjugation and oligomerization of SUMO-3106
Neonatal perturbation of KCC2 and NKCC1 co-transporters in the developing vestibular nucleus impairs vestibular functions33
Understanding sedlin and the molecular basis of spondyloepiphyseal dysplasia tarda210
In vivo analysis of the functional specificity of the transcription factor, SOX9, in regulation COL2A1/Col2a174
Immunohistochemical localization of chondroitin sulfate proteoglycans in the developing rat hindbrain90
Role(s) of p53/p63 in chondrocyte re-differentiation upon activation of ER stress263
Understanding the Function of the SEDL Gene and the Molecular Pathogenesis of Spondyloepiphyseal Dysplasia Tarda50
The effect of pollutant-induced cellular stress on mRNA stability27
ER-stress induces early onset intervertebral disc degeneration in a mouse model for metaphyseal chondrodysplasia type Schmid73
Fos expression in otolith-related brainstem neurons of postnatal rats following off-vertical axis rotation99
Topographical Sagittal Profile in 620 Patients Measured By A Novel Handheld Device43
Detection of extracellular matrix degradation in intervertebral disc degeneration by diffusion magnetic resonance spectroscopy (DW-MRS)81
Detection of crystallization inhibitory activity of whole urine with a gel model105
Single-nucleotide polymorphisms near the microsatellite D17S1303 and the development of hypertension in a 6-year longitudinal study107
Toll-like receptor 10 is involved in induction of innate immune responses to influenza virus infection265
Uncovering essential gene function for sensory organ development in the mammalian inner ear57
Computational construction of the downstream network of Pax6 in AD neuronal death model67
Functional significance of the AU-rich sequence element in the mRNA of the stress- inducible protein CHOP/Gadd15352
Targeted correction of a chromosomal point mutation by modified single-stranded oligonucleotides in a GFP recovery system117
Regulation of secondary heart field development by epigenetic chromatin remodeling factor BAF250a206
Fine-tuning of notochord midline position via cell-matrix interactions68
Salvianolic acid B inhibits hydrogen peroxide-induced endothelial cell apoptosis through regulating PI3K/Akt signaling192
Delayed endochondral ossification and digit joint formation in mice expressing a brachydactyly type A1 mutation in Indian Hedgehog65
Engineering Bacterial Chromosomes: E. coli and Beyond72
The Irx3 and Irx5 genes in inner ear development55
Clinical and genetic study of a large Italian family linked to SPG12 locus143
Identification and characterization of a novel liver-enriched transcription factor of the bZIP family69
IGG3: A tool to rapidly integrate large genotype datasets for whole-genome imputation and individual-level meta-analysis120
The effect of severity of degeneration on intervertebral disc regeneration by use of mesenchymal stem cells52
Oral viral vector gene delivery111
Development of 3D system for culturing notochordal cells96
Hedgehog/notch-induced premature gliogenesis represents a new disease mechanism for Hirschsprung disease in mice and humans128
Mesenchymal stem cell-collagen microspheres for articular cartilage repair: cell density and differentiation status.102
Identification of genes with allelic imbalance on 6p associated with nasopharyngeal carcinoma in Southern Chinese133
Genetic basis of skeletal dysplasia, ear development & congenital deafness – lessons from mose models of human malformations29
A Novel Non-invasive Role of Heparanase: Promotion of Cartilage Matrix Mineralization59
In vivo functional analysis of SOX9 by conditional expression of a mutant Sox9, Sox9Y440X, in the notochord73
The role of SoxE transcription factors in melanoma development403
Sox10 is essential for neural crest invasion in cochleo-vestibular ganglion89
Kinesin-1 is necessary for cytokinesis in chondrocytes68
Effect of ventral prostate secretory proteins on oviductal fluid glycoproteins in golden hamsters49
Kinesin-1 is necessary for cytokinesis in chondrocytes84
Defective prelamin A processing and muscular and adipocyte alterations in Zmpste24 metalloproteinase-deficient mice190
Unfolded Protein Response Leading to Cataratogenesis in a Microphthalmia Cataract Mouse Mutant68
Derivation of Fate-Committed Schwann Cells from Bone Marrow Stromal Cells of Adult Rats50
Aligned chitosan nano-fibers for nerve regeneration68
The influence of progenitor cells in intervertebral disc degeneration and regeneration40
Presence of notochord descendent cells in the nucleus pulposus of adult mice showing signs of intervertebral disc degeneration86
Novel sequence motif regulates pluripotency55
Regulatory role for a novel human thioredoxin peroxidase in NF-κB activation96
Hoxb3 is involved in the endothelin-1 signaling pathway in patterning the facial branchial arches88
Genome-wide association study of adolescent idiopathic scoliosis in Southern Chinese and significant improvement in detection of missing heritability and genetic risk prediction in genome-wide association studies by 1000 genomes-based imputation205
Targeting the SARS coronavirus helicase - three approaches to inhibitor development54
Increased efficiency of oligonucleotide-mediated gene repair through slowing replication fork progression105
Gelatinase A (MMP-2) activation by skin fibroblasts: dependence on MT1-MMP expression and fibrillar collagen form105
Combinatorial use of chondroitin sulphate lyase subtypes in the treatment of nerve injury1394
Targeting of DICE1 tumor suppressor by Epstein-Barr virus-encoded miR-BART3* microRNA in nasopharyngeal carcinoma118
Functional Role of MT1-MMP in FGF Signaling57
Subcellular localization of sars coronavirus orf8 protein63
Pax6/c-Myb regulates neuronal apoptosis in a mouse model of Alzheimer's disease401
A study of membrane-bound neuregulin in mediating fate commitment of Schwann cell-like cells274
NRProF: neural response based protein function prediction algorithm52
Hypoxia-related and Stem Cell-like Phenotypes of Young, Adult and Aged Intervertebral Disc Cells73
Expression of chondroitin sulfotransferases in the injured spinal cord85
PDZ-domain containing-2 (PDZD2) drives the maturity of human fetal pancreatic progenitor-derived islet-like cell clusters with functional responsiveness against membrane depolarization145
Requirement of N-linked glycosylation in the luminal domain for optimal proteolytic activation of liver-enriched transcription factor CREB-H53
Irx3 and Irx5 regulate cochlear hair cell specification and differentiation56
Identification of novel serum metabolomic biomarkers related to the development of lumbar disc degeneration55
SARS-CoV S protein induces strong mucosal immune responses and provides long-term protection against SARS-CoV infection61
Investigating the role of SOX9 in human neural stem cells44
Context dependent impact of the Y440X campomelic dysplasia Sox9 mutation94
Essential and dose-dependent requirement for the sedlin component of the trapp complex in development70
Activation of epidermal-growth factor receptor leads to growth inhibition and phosphorylation of the SHC-protein in a human nasopharyngeal cell line68
A study of the effects of morphine in relation to adrenal hormone activity186
NMR study of the conformational transition of cytochrome c upon the displacement of Met80 by exogenous ligand: Structural and magnetic characterization of azidoferricytochrome c98
Novel plasma modified shape memory materials for orthopaedic implantation57
Migratory behaviours of sacral neural crest cells in the hindgut of mouse embryos as shown by live cell imaging77
From loss to gain: role for SUN1 in laminopathies45
Type X collagen multimer assembly in vitro is prevented by a Gly618 to Val mutation in the α1(X) NC1 domain resulting in Schmid metaphyseal chondrodysplasia98
Characterization of molecular and cellular consequences in OI type V osteoblasts44
Heparanase expression in neurons and Schwann cells that emigrated from dorsal root ganglion explants in culture60
KIF5b is essential for growth plate organization, cytokinesis and chondrocytes differentiation54
Mechanism behind the fate commitment of bone marrow-derived schwann cells53
Guidance of DRG neurons in fate determination of bone marrow derived Schwann cells79
Versatile Metal-Ligand Chromophoric Building Blocks – From Design to Supramolecular Assembly and Functions27
Pharmacokinetics of homoharringtonine in Chinese leukemia patients223
Nucleic acid aptamers against ADAMTS as a new therapeutic approach against degenerative disc disease78
Development Of Three-Dimensional System For Culturing Notochordal Cells65
Chondroitinase treatment enhances axonal regrowth through schwann cell-seeded channels after spinal cord hemisection in adult rats87
Thioredoxin-related protein 32 is an arsenite-regulated thiol reductase of the proteasome 19 S particle186
Recombinogenic tagging reveals dynamic compartmentalization of the escherichia coli proteome69
Serglycin in neutrophils: retention of neutrophil elastase in granules and inhibition of neutrophil elastase activity during storage48
The pathogenic mechanisms and therapeutic strategies of hutchinson-gilford progeria syndrome75
Expression of chondroitin sulfotransferases in the injured spinal cord63
Quantitative nucleolar proteomics reveals nuclear re-organization during stress-induced senescence in mouse fibroblast114
Functional roles of rarely-used synonymous codon and sequences variation in type I cytokine receptors191
In vitro studies on the mechanism of homologous DNA recombination promoted by Escherichia coli RecA protein189
Toward maturation of the vestibular system: Neural circuits and neuronal properties98
A fast and accurate SNP detection algorithm for next-generation-sequencing data19
Alleles at the Nicastrin locus modify presenilin 1-deficiency phenotype114
Timeless interacts with Parp1 to promote homologous recombination repair166
The proNGF-p75NTR-sortilin signalling complex as new target for the therapeutic treatment of Parkinson's disease136
Electrophoretic behaviour of polystyrene microspheres in agarose gels218
The effect of salvianolic acid B combined with laminar shear stress on TNF-α-stimulated adhesion molecule expression in human aortic endothelial cells99
Deleted in liver cancer 2 (DLC2) suppresses cell transformation by means of inhibition of RhoA activity140
The APOE-ε4 allele and Alzheimer disease among African Americans, Hispanics, and whites [3] (multiple letters)83
Structural Insights of the Specificity and Catalysis of a Viral Histone H3 Lysine 27 Methyltransferase104
Integration of factors and pathways facilitating chondrocyte adaptation to ER stress50
Genomic isolation and molecular analysis of a rat [alpha]-globin gene cluster162
Rational design and development of small interfering RNAs and small hairpin RNAs for inhibition of hepatitis C virus replication48
A rat serum glycoprotein whose synthesis rate increases greatly during inflammation67
Insight into the molecular pathogenesis of campomelic dysplasia revealed by a conditional Sox9 mutant mouse model75
Studies on the molecular mechanism of morphogenetic defects in brachydactyly type A-151
Mechanistic insight into point mutations in sedlin that result in spondyloepiphyseal dysplasia tarda61
Deleted in liver cancer (DLC) 2 encodes a RhoGAP protein with growth suppressor function and is underexpressed in hepatocellular carcinoma141
Identifying small molecules for regulating proteoglycan metabolism in cartilaginous tissues40
Aptamer-mediated inhibition of sclerostin for osteoporosis therapy98
The role of procollagen IIA as a facilitator of BMP signaling in Heart development49
Reduction of Placental Thioredoxin Expression in Diabetic Pregnancies77
iPS Reprogramming in Premature Aging Mouse Model - Zmpste24 Deficient Mice57
Structural studies of glucose-6-phosphate and NADP+ binding to human glucose-6-phosphate dehydrogenase96
Role of heparanase 1 and heparanase 2 in modulating synaptic activities90
The Regulatory Role of Heparanase in Synaptic Plasiticity at Hippocampus72
Association of ICAM3 genetic variant with severe acute respiratory syndrome174
Collagen-mesenchymal stem cell microspheres for regenerative medicine81
Solution structure of cyanoferricytochrome c: Ligand-controlled conformational flexibility and electronic structure of the heme moiety125
Derivation of Schwann cells from mammalian skin and bone marrow for use in axonal regeneration71
Chondroitinase ABC-I and -II linked chitosan microbeads improve axonal regrowth in CSPG-upregulated astrocyte culture1340
Over-expression of FOXM1 transcription factor is associated with cervical cancer progression and pathogenesis142
Maturation profile of inferior olivary neurons expressing ionotropic glutamate receptors in rats: role in coding linear accelerations108
Hyaluronans: Crystallization-promoting activity and HPLC analysis of urinary excretion61
Binding sites for transcription factor NTF-1/Elf-1 contribute to the ventral repression of decapentaplegic105
Neural specificity of elav expression: Defining a Drosophila promoter for directing expression to the nervous system103
Exploring functional variation affecting miRNA and ceRNA regulation in humans74
Genomic Analysis of Increased Osteoblast Activity in a Mouse with generalized Hyperostosis44
Screening small molecule ihibitors against proteoglycan degradation to control tissue degeneration89
Stimulation of non-amyloidogenic processing of amyloid-β protein precursor by cryptotanshinone involves activation and translocation of ADAM10 and PKC-α124
Plasticity of GABAergic synapses in the developing vestibular nucleus governs the expression of spatial navigation in mature rats64
Human TRBP and PACT directly interact with each other and form a complex with Dicer to promote the production of small interfering RNA61
Genomic instability caused by unprocessed prelamin A contributes to premature aging in mice lacking Zmpste2452
Separation and identification of crystal-active urinary glycosaminoglycans63
Spatially-specific regulation of the mouse Hox-B3 gene expression64
Analysis of multiple cardiac abnormalities of a mouse mutant Hoxb3lacZ78
NOA1 is an essential GTPase required for mitochondrial protein synthesis107
Towards remyelination therapy with oligodendrocyte precursor and Schwann cells derived from bone marrow stromal cells1081
Deregulation of Cybb prevents myeloid differentiation in Mll-Een Leukemia Cell35
The mRNAs for the three chains of human collagen type XI are widely distributed but not necessarily co-expressed: Implications for homotrimeric, heterotrimeric and heterotypic collagen molecules97
In vivo analysis of the transactivation specificity of group E SOX proteins56
Mechanisms of hereditary factors58
Anterior/Posterior-specific Properties of Adult Spinal Cord Neural Progenitor Cells76
MT1-MMP-dependent and -independent regulation of gelatinase A activation in long-term, ascorbate-treated fibroblast cultures: Regulation by fibrillar collagen123
Gene and Protein Expression Profiles of the Intervertebral Disc: In Health and Disease - A General Overview44
The human α2(XI) collagen gene (COL11A2) maps to the centromeric border of the major histocompatibility complex on chromosome 6134
Molecular analyses of chondrocyte differentiation and adaptation to ER stress269
Comparative analysis of bZIP transcription factors of the CREB3 subfamily233
Myosin-1a is critical for normal brush border structure and composition78
Next generation sequencing has lower sequence coverage and poorer SNP-detection capability in the regulatory regions46
The Role of Cyclooxygenase 1 and 2 in Bone Repair62
A3.5 Molecular pathogenesis of SEDT: the role of sedlin and its cytoplasmic function102
Regulation of Sox9 function by SUMOylation in avian neural crest development65
Electrophoretic separation and characterization of urinary glycosaminoglycans and their roles in urolithiasis102
Coping With Stress in Hypertrophic Chondrocytes: The Role of PERK Pathway121
A mutation in Ihh that causes digit abnormalities alters its signalling capacity and range177
Glucose-6-phosphate dehydrogenase deficiency in female octogenarians, nanogenarians, and centenarians171
Abnormal regulation of cartilage and bone growth in transgenic mice expressing a collagen X SMCD mutation76
Epstein-Barr virus-encoded microRNA targets PUMA to promote tumor cell survival119
Evaluation of next-generation sequencing software in mapping and assembly179
Developmental plasticity of GABAergic synapses in medial vestibular nucleus of rats1337
Parallel, Beneficial Genome Reduction During Adaptation of Experimental Populations29
The methylated purine content of liver tRNA and of urine in cases of hepatocellular carcinoma186
The role of autophagy in ER-stress induced chondrocyte re-differentiation56
Sox2 as a master regulator of prosensory development in the mouse inner ear25
GWASdb: A database for human genetic variants identified by genome-wide association studies170
Insights into the molecular pathogenesis of campomelic dysplasia caused by mutations in Sox931
A discriminatory DNA aptamer for malaria diagnostics from the blind watchmaker23
Abnormal chondrocyte differentiation: a transgenic model194
Mouse Model of Familial Parkinson’s Disease based on Variant Leucine Rich Repeat Kinase 2 (LRRK2)74
星形膠質性蛋白多糖對大鼠胚胎皮層神經元貼附, 存活和生長的影響: 星形膠質細胞神經元的體外共培養研究73
The epstein-Barr virus encoded latent membrane protein-1 protects cells against caspase-independent apoptosis43
Stimulation of the k-receptor in cultured cardiomyoblast produced different combinations of intracellular signals at low and high concentrations of specific k-agonists56
Cloning and characterization of a Sprague-Dawley rat a-globin gene haplotype78
The expression of P21/WAF1/CIP1 is not sufficient to mediate the anti-apoptotic action of Epidermal-Growth-Factor Receptor44
A centrosomal target of human T-cell leukemia virus type I oncoprotein Tax on the road to genome instability66
Structural and functional insight into the mechanism of an alkaline exonuclease from Laribacter hongkongensis109
Bridge-1, a novel PDZ-domain coactivator of E2A-mediated regulation of insulin gene transcription77
Virtually there: a journey to the HKU Medicine Island for teaching and learning66
Linkage analysis of familial early-onset degenerative disc disease (DDD)62
Bioinformatic studies of gene regulation involving SOX9 and the SOX family150
ChIP-array: combinatory analysis of ChIP-seq/chip and microarray gene expression data100
Identification of plasmin as the major contaminant in immunoglobulin preparations115
Expression and functions of FOXM1 in human embryonic stem cells218
Chondrogenic differentiation of human mesenchymal stem cells in three-dimensional collagen/chondroitin-6-sulfate gels: Influences of cell seeding density and collagen concentration67
Transmembrane collagen XVII, an epithelial adhesion protein, is shed from the cell surface by ADAMS97
PLK1 phosphorylates mitotic centromere-associated kinesin and promotes its depolymerase activity152
Novel mutations of SOX10 suggest a dominant negative role in Waardenburg-Shah syndrome.102
Roles of notch and ErbB signaling in the fate commitment of bone marrow-derived Schwann cells41
The role of Irx3/5 in regulating lineage progression of hypertrophic chondrocyte to osteoblasts50
Heparan Sulfates and Heparanase in the Mineralizing Matrix of Developing Mouse Growth Plate61
Bayesian detection of embryonic gene expression onset in C. elegans122
SWI/SNF in cardiac progenitor cell differentiation75
Characterization of a type I collagen α2(I) glycine-586 to valine substitution in osteogenesis imperfecta type IV. Detection of the mutation and prenatal diagnosis by a chemical cleavage method71
Role of type II collagen turnover in disc development and degeneration80
Sox2 is required for sensory organ development in the inner ear63
Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia199
Mechanistic insights into chondrodysplasia caused by ER-stress revealed by genetic and transcriptome analyses60
Association of ABCA1 gene with Sporadic Alzheimer's Disease in Chinese Group and potential functional importance for Novel Intronic Polymorphism79
Chondroitin sulfates restrict axonal growth along the projection path of VN neurons across the hindbrain of prenatal Sprague-Dawley rats78
Shape transformation of the nuclear envelope during closed mitosis61
Quantitative single-step purification of dinucleoside polyphosphates86
Preparation of electrospun chitosan fibres for Schwann cell-guided axonal growth238
Inhibition of SARS Coronavirus by Bismuth compounds84
Development of a bioinformatics and statistical framework to integratebiological resources for genome-wide genetic mapping and itsapplications249
Loss of β-catenin in hypertrophic chondrocytes results in abnormal bone formation59
Divergent routes for derivation of alternative glial cell fate from adult bone marrow stromal cells for remyelination therapy45
Developmental distribution of vestibular nuclear neurons responsive to different speeds of horizontal translation111
MIP-T3 is a negative regulator of innate type I IFN response79
Investigation of the lineage and tissue specificity of genes77
DNA methylation status influences expression of human neuroglobin gene65
Developing vestibular commissural projections display differential patterns with chondroitinase treatment of the hindbrain60
Investigation of the Role of Kif5B in Pancreatic β-cells Function58
Linkage analysis on familial early onset degenerative disc disease105
Demonstration of the presence of plasminogen activator in human small intestine99
Sox10 mutation affects gliogenesis of the cochleo-vestibular ganglion in mouse inner ear development77
Prelamin A compromises DNA Damage-induced Chromatin Relaxation to Promote Genomic Instability and Aging65
Cloning, expression, purification and characterisation of escherichia coli polyphosphate binding domain as a new tool to understanding polyphosphate synthesis and function54
Genetic control of chondrocyte adaptation to ER stress in chondrodysplasia62
Lanthanides: Upconversion Nanoparticles for Bioimaging Applications122
The autocrine sPDZD2 protein is a potential p53 activator81
Generation and characterization of polyclonal antibodies specific to the mouse homeodomain protein HOXB-3198
The role of fibronectin and atypical protein kinase C iota in the development of notochord and chondrocytes237
Induction of osteo-chondroprogenitor formation by defined transcription factor-mediated reprogramming process61
Genetic analysis of the role of procollagen IIA as an extracellular regulator of BMP signaling51
Regulation of mouse Hoxb3 gene expression in the anterior neural tube and vagal neural crest52
Phenotypic and biochemical consequences of collagen X mutations in mice and humans83
Recent progress in the study of the intracellular functions of diadenosine polyphosphates250
EpiRegNet: constructing epigenetic regulatory network from high throughput gene expression data for humans79
Urinary glycosaminoglycans and crystallization of urinary calcium oxalate56
AdIkBa-mediated apoptosis in Epstein-Barr virus positive nasopharyngeal carcinoma C666-1 cells199
The double-stranded RNA-binding protein PACT functions as a cellular activator of RIG-I to facilitate innate antiviral response158
Effects of visible light on cells, subcellular organelles and enzymes185
Coming together is a beginning: The making of an intervertebral disc123
Herpes simplex virus type 1 Us11 protein inhibits type I interferon production by suppressing PACT induced activation of RIG-I58
Interplays between RNA-binding proteins determine viral infection outcome66
The role of Pax6 in Beta-Amyloid toxicity and Alzheimer’s disease1244
An α-2-macroglobulin insertion-deletion polymorphism in Alzheimer disease [5] (multiple letters)80
Effects of chondroitin sulfate supplements on regeneration of bridged sciatic nerves65
Functional analysis of a secreted PDZ-containing protein sPDZD276
Investigating the regulatory role of foxmi in cell cycle progression by RNA interference57
A proteomic approach to study the molecular mechanisms of the unfolded protein response in the endoplasmic reticulum of chondrocytes53
LY294002 and metformin cooperatively enhance the inhibition of growth and the induction of apoptosis of ovarian cancer cells130
A comprehensive database for GWAS¬identified human genetic variants: an update of GWASdb153
Towards myelin repair in the CNS: oligodendrocyte precursors derived from bone marrow stromal cells134
Biochemical and electrophysiological studies on the effects of morphine on dopaminergic neurotransmission in the caudate nucleus ofrats195
Carboxyl-terminal fragments of alzheimer β-amlyloid precursor protein accumulate in restricted and unpredicted intracellular compartments in presenilin 1-deficient cells150
Severe acute respiratory syndrome coronavirus M protein inhibits type I interferon production by impeding theformation of TRAF3·TANK·TBK1/IKKε complex97
Induction of osteo-chondroprogenitors formation during transcription factor-mediated reprogramming processes57
Fate Commitment in Bone Marrow Stromal Cell Derived Schwann Cells is Dependant on Axonal Contact100
Modulating proteoglycan metabolism using small molecules as treatment for disc degeneratioin56
Association of MAD2 expression with mitotic checkpoint competence in hepatoma cells120
Endocannabinoid regulates long-term synaptic plasticity contributing to the acquisition of vestibular behavior during postnatal development56
Influenza A virus NS1 protein targets double-stranded RNA binding protein PACT to suppress innate antiviral response56
The role of SOX10 in enteric neural crest cell migration51
Special tribute to KT Jeang26
Characterization of the complete genomic structure of the human WNT-5A gene, functional analysis of its promoter, chromosomal mapping, and expression in early human embryogenesis100
Type X collagen NC1 mutations produced by site-directed mutagenesis prevent in vitro assembly54
Over-expression of Hoxb3 affects inner ear neurogenesis83
The role of PERK pathway in adaptation of hypertrophic chondrocytes to ER stress72
Melatonin inhibits the proliferation of hormone-refractory prostate cancer cells by up-regulating p27 Kip1 expression and down-regulating activated androgen signal transduction via membrane MT1 receptor activation.70
Identifying the DNA binding specificity of Hoxb-356
Role of heparanase in synaptic plasticity at the hippocampus and vestibular nucleus71
ErbB receptor modulation by the Notch pathway as a means to fate commitment in bone marrow-derived Schwann cells227
The APC regulator CDH1 is essential for the progression of embryonic cell cycles in Xenopus124
Tax-induced recruitment of TORC family coactivators is required for transcriptional activation of the human T-cell leukemia virus type 1 long terminal repeats59
Structural basis of FliG-FliM interaction in Helicobacter pylori.47
Biochemical heterogeneity of type I collagen mutations in osteogenesis imperfecta.68
Sox2 as a prosensory and proneural gene in the developing mouse cochlea.79
Regulation of NRG3 neurotrophic factor causes instigation on neuritic elongation and surviral by a novel phosphatase PTPN2177
Solution structures, dynamics, and lipid-binding of the sterile α-motif domain of the deleted in liver cancer 2121
Strontium combined with calcium increases vertebral bone mineral density and stiffness in goats66
Some effects of morphine and hydrocortisone on glucose utilization in rat diaphragm225
Carbohydrate and core protein components of perineuronal net play differential roles in functional modifications of vestibular nuclear neurons in the rat63
Interaction of collagen a1(X) containing engineered NC1 mutations with normal alpha1(X) in vitro. Implications for the molecular basis of schmid metaphyseal chondrodysplasia58
Identification and characterization of TXBP151, a novel cellular target of HTLV-ITAX67
Formation of novel pattern by programming cell motility82
Changing in potassium sensitivity in muscle of chronically morphinizedrats175
Formation of CAPO4 and Suppression of Ni Leaching in Nitinol Using Oxygen and Sodium Plasma Immersion Ion Implantation109
Three genes in the aggrecan degradation pathway act synergistically to predispose to degenerative disc disease129
Expression of the Trp2 allele of COL9A2 is associated with alterations in the mechanical properties of human intervertebral discs103
The effects of cyclooxygenase -2 selective non-steroidal anti-inflammatory drugs (NSAIDs) in fracture repair48
Signal transduction mechanisms regulating transferin receptor gene expression during phorbol ester-induced human leukemic HK-60 cells82
A study of biological role of reactive oxygen species in cellular response in stress293
Systematic review on the efficacy and safety of herbal medicines for Alzheimer's disease104
Glycosaminoglycan control of oxalate transport across cultured renal cells62
A splicing mutation in the ext2 gene affects messenger RNA stability in a family with hereditary multiple exostoses99
The function of kinesin-1 mediated intracellular transportation in long bone development89
Missense mutations in IHH impair Indian hedgehog signaling in C3H10T1/2 cells: Implications for brachydactyly type A1, and new targets for hedgehog signaling139
Multiple coding and non-coding RNAs in the Hoxb3 locus and their spatial expression patterns during mouse embryogenesis132
Induction of ornithine decarboxylase activity in reuber H-35 hepatoma cells by systems A and N amino acids and the possible involvement ofthe Na+/H+ antiporter183
Cholesterol-induced mammary tumorigenesis is enhanced by adiponectin deficiency: role of LDL receptor upregulation75
Phosphatidylinositol 3-kinase and protein kinase C are required for the inhibition of caspase activity by epidermal growth factor80
Intervertebral disc degeneration: New insights based on "skipped" level disc pathology84
Neuronal expression of heparanase 1 and heparanase 283
Differential involvement of perineuronal net components in functional modifications of rat vesticular nucelar neurons59
The torso response element binds GAGA and NTF-1/Elf-1, and regulates tailless by relief of repression83
Defective Self-renewal And Early Cellular Senescence In Premature Aging Mesenchymal Stem Cells53
Varying expression of chondroitin sulfotransferases for cranial motor neuron migration in rat hindbrain development46
Identification of EEN, a novel gene that fuses to HRX in a t (1 1; 1 9) (q23;p 1 3) in acute leukemia92
Isothermal titration calorimetry reveals a zinc ion as an atomic switch in the diadenosine polyphosphates98
Distinctive functions of membrane type 1 matrix-metalloprotease (MT1-MMP or MMP-14) in lung and submandibular gland development are independent of its role in pro-MMP-2 activation109
Homeobox gene HOXB5 is required in the embryonic development of the enteric nervous system69
Melatonin as a negative mitogenic hormonal regulator of human prostate epithelial cell growth: Potential mechanisms and clinical significance97
In vivo study of asporin function in cartilage tissues235
Purification and characterization of the ganglioside-stimulated protein kinase in mammalian brain59
A proteomic approach for the identification of bismuth-binding proteins in Helicobacter pylori112
The effect of mutating the PDZ domains within secreted PDZ-domain-containing protein 2 on its insulinotropic action in INS-1E cells198
Cyclin-dependent kinase 5 supports neuronal survival through phosphorylation of Bcl-283
Recovering isoform specific gene regulatory networks from RNA-SEQ data46
Exploring the sequence patterns in the α-helices of proteins81
Ectopic Hoxb-3 expression causes cranial ganglial nerve and pharyngeal arch defects and leads to transformation of vertebrae47
Strategy to study urinary glycosaminoglycans by high performance liquid chromatography57
Lithium ion alters Ins (1,4,5) P3 production and mobilisation of intracellular free calcium in K-agoinst stimulated rat ventricular myocytes67
Proheparanase regulates synaptic plasticity of the hippocampus62
Proheparanase action at excitatory synapses : implication on synaptic plasticity230
Effect of ascorbic acid on the metabolism of dimethylnitrosamine and diethylnitrosamine165
Expression of chondroitin 6-sulfate in neuroepitheilial boundaries in mouse embryos64
Towards the understanding of nickel trafficking in helicobacter pylori: expression and characterization of a his-rich protein, HPN64
Disrupted expression of matrix genes in the growth plate of the mouse cartilage matrix deficiency (cmd) mutant139
Identification of novel small-molecule inhibitors of severe acute respiratory syndrome-associated coronavirus by chemical genetics171
Notch signaling mediates the switch to fate commitment of bone marrow-derived Schwann cells65
RecA protein-promoted homologous pairing and strand exchange between intact and partially single-stranded duplex DNA116
Fate commitment in bone marrow stromal cells derived Schwann cells is dependant on axonal contact109
Significance of MAD2 expression to mitotic checkpoint control in ovarian cancer cells152
Segmental expression of Hoxa-2 in the hindbrain is directly regulated by Krox-2083
Inhibition of E3 ubiquitin ligase WWP1 with SELEX generated DNA aptamers63
An improved method for cell traction force measurement66
A novel peptide with potent and broad-spectrum antiviral activities against multiple respiratory viruses141
The localization of E. coli persistent gene products272
In Vitro Selection of HIV-1 CRF08_BC Variants Resistant to Reverse Transcriptase Inhibitors 60
Shape transformation of the nuclear envelope during closed mitosis54
Isolation and characterization of an X-linked housekeeping gene from aChinese177
Linkage analysis with subsequent fine-mapping on familial early onset-degenerative disc disease.77
Characterization of novel putative tumor suppressor gene, DLC2 (deleted in liver cancer 2), in hepatocellular carcinoma81
Enrichment of committed human nucleus pulposus cells expressing chondroitin sulfate proteoglycans under alginate encapsulation74
Exchange protein directly activated by cAMP 1 is involved in β3-adrenergic induction of brown adipose tissue in white adipose tissue66
Cadherin 2 as human notochordal cell marker and its expression pattern in disc degeneration93
Requirement of N-linked glycosylation in the luminal domain for optimal proteolytic activation of liver-enriched transcription factor CREB-H66
Regeneration of nucleus pulposus cells for degenerative disc disorder55
Cre expression in the node and notochord in transgenic mice driven by FOXA2 minimal nothchord element79
Transgenic mouse models of human skeletal disorders60
Endocannabinoid modulates developmental plasticity of central vestibular synapses andthe expression of vestibular behaviors in rats71
Polymer encapsulated human osteoblastic cells form ectopic bone in mice67
Upregulation of chondroitin 6-sulphotransferase-1 facilities Schwann cell migration during axonal growth106
Kappa-opioid receptor potentiates apoptosis via a phospholipase-C pathway in the CNE2 human epithelial tumor cell line73
Yeast arginine methyltransferase Hmt1p regulates transcription elongation and termination by methylating Npl3p111
Hypertrophic chondrocytes under ER stress utilizes the hypoxia stress pathway for survival49
Development of an inter-kingdom delivery and expression system for therapeutic molecules against cancer214
Chondroitin sulfotransferase expression pattern for the regulation of cranial motor neuron migration in rat embryonic hindbrain82
Generation of mouse models to study intracellular transportation in purkinje cells and melanocytes169
Expression of chondroitin sulfotransferases in cranial motor neurons in the embryonic rat hindbrain53
The role of Pax6 in beta-amyloid induced neuronal death42
Cell to cell spreading of RNAi in mammalian cell52
Genome-wide association study of Scoliosis in Southern Chinese7
The Role of Sox 10 in Mouse Inner Ear Development65
Identification and characterization of a novel liver-enriched transcription factor of the bZIP family54
Roles of Sox4 in central nervous system development144
Sox2 and inner ear development239
Hypertrophic Chondrocytes Can Become Osteoblasts and Osteocytes in Endochondral Bone Formation110
Semaphorin 3A and chondroitin sulphate proteoglycan networks of perineuronal nets regulate the developing central vestibular circuitry53
Genome-wide association study of Degenerative Disc Disease (DDD)153
Regulation of synaptic plasticity by the partnership of proheparanase with peri-synaptic heparan sulfate proteoglycan and AMPA-type glutamate receptor1168
Changes in glycosaminoglycans during regeneration of post-crush sciatic nerves of adult guinea pigs173
Sox10 is essential for neural crest invasion in cochlea-vestibular ganglion39
Defining the function of type X collagen in skeletal development166
DNA lesions occur with loss of viability in embryos of ageing rye seed73
Assessment of next generation sequencing analysis tools shows lower coverage and poorer SNP-calling quality in the CpG islands and regulatory regions52
An integrated approach for identification of metallodrug binding proteins in cells39
Neutrophil elastase binds serglycin during storage in granules and changes its binding partner to shed syndecan-1 after degranulation56
Expression of heparanase and syndecan-3 are colocalized in mouse growth plate54
Activation of translocation of CDC2 in dexamethasone-induced apoptotic human nasopharyngeal carcinoma CNE3 cells61
Isthmin and its relation to FGF signalling during chick embryonic development35
Molecular and developmental insights into the pathogenesis of the SOX9Y440X campomelic dysplasia mutation66
In vitro and In vivo biocompatibility od dual carbon and nitrogen plasma modified titanium alloy49
Genetic analysis of the role of MMP14 during endochondral ossification60
Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and βAPP processing103
Role of yeast peroxiredoxin, Tsa1p, in DNA damage response68
Collagen-mesenchymal stem cell microspheres for the repair of articular cartilage defects in a rabbit model.60
EpiRegNet: constructing epigenetic regulatory network from high throughput gene expression data for humans54
An Investigation of the Mutual Relationship between ER Stress and Oxidative Stress73
Cross talk between Hox genes and sonic hedgehog signaling during mousehindbrain neurogenesis182
Synthesis and expression in Escherichia coli of a human neutrophil activating protein-1/interleukin-8 gene.109
Mouse model with impaired matrix remodeling in endochondral ossification38
Differential stability and transcriptional activity of CREB3 subfamily transcription factors60
Expression profiling and epigenetic regulation of Hox genes in cellular models of chondrogenesis177
Regeneration of nucleus pulposus cells for degenerative disc disorder52
Tissue Engineering for Intervertebral Disk Degeneration114
Molecular Basis for Gerodermia Osteodysplastica, a Prematured Aging Disorder63
Changes in perineuronal nets within the rat vestibular nuclei during development and after unilateral labyrinthectomy73
Different mutations in sedlin cause X-linked spondyloepiphyseal dysplasia tarda via two distinct mechanisms: protein misfolding and protein-protein interaction Abrogation88
Studies of heparanase (HPA) gene expression, cellular localization andfunctions in neural tissues of the rat187
Identifying genetic mutations in patients with Rasopathies using a Next Generation Sequencing Diagnostic Pipeline in Hong Kong115
Protein tyrosine phosphatase non-receptor 21 (PTPN21) contributes to Elk-1 dependent NRG3 transcription in mice cortical neuron model68
Mouse model with impaired collagen X degradation at the chondro-osseous junction49
Anion exchange in human serum transferrin N-lobe: a model study with variant His249Ala 43
Small interfering RNA targeting M2 gene induces effective and long term inhibition of influenza A virus replication93
Mechanism study on two DNA repair systems49
Abnormal chondrocyte differentiation and chondrodysplasia in transgenic mice101
Ectopic expression of Hoxb-3 in rhombomere 4 suppresses Hoxb-1 expression77
A novel gene IC53 stimulates ECV304 cell proliferation and is upregulated in failing heart102
Loops, hairpins and flipped bases: a DNA aptamer that discriminates Plasmodium lactate dehydrogenase from the blind watchmaker109
Identification and characterization of a novel liver-enriched transcription factor of the BZIP family59
Identification and characterization of long-range SOX9 enhancers in limb development57
MetaProm: A neural network based meta-predictor for alternative human promoter prediction106
Rabbit articular cartilage repair using collagen-mesenchymal stem cell microspheres88
Controlling mitochondria distribution with chimeric proteins38
Up-regulation of human secreted frizzled homolog in apoptosis and its down-regulation in breast tumors79
The role of Sox10 in enteric neural crest cell migration42
Mutation of conserved aspartates affect maturation of presenilin 1 and presenilin 2 complexes99
Novel presenilin 1 mutations associated with early onset of dementia in a family with both early-onset and late-onset Alzheimer disease158
Association between promoter - 1607 polymorphism of MMP1 and lumbar disc disease in Southern Chinese131
Investigating the role of the forkhead box transcription factor FOXM1 against oxidative stress and DNA damage in human embryonic stem cells210
The influence of the outflow of the Pearl River on the waters of the South China Sea: with special reference tothe phosphate and nitrate content215
Identity-by-descent approaches identify regions of importance of genetic susceptibility to hereditary esophageal squamous cell carcinoma126
LKB1 tumor suppressor is a negative regulator of Tax-mediated transcriptional activation of human T-cell leukemia virus type 1 long terminal repeats65
Stable expression of EBERs in immortalized nasopharyngeal epithelial cells confers resistance to apoptotic stress121
Sox10 regulates enteric neural crest cell migration in the developing gut1243
Age-dependent association of the Trp2 allele of the COL9A2 gene with intervertebral disc degeneration in Southern Chinese89
Identification of 3' splicing variants of receptor tyrosine kinase encoding gene RET in mouse and expression study of RET splicing variants in developing mouse embryo90
Investigation of Cardiovascular Defects in a Mouse Mutant HOXB3LACZ59
Epigenetic regulation and stem cell contribution in HGPS32
A 3D collagen microsphere culture system for GDNF-secreting HEK293 cells with enhanced protein productivity181
Identification of major histocompatibility complex class I C molecule as an attachment factor that facilitates coronavirus HKU1 spike-mediated infection100
Tenogenic differentiation of human mesenchymal stem cells on novel bio-imprinted scaffolds59
MIT-MMP in FGF signaling67
Investigation of nickel suppression and cytocompatibility of surface-treated nickel-titanium shape memory alloys by using plasma immersion ion implantation106
Principles of Developmental Genetics105
ChIP-Array 2: integrating multiple omics data to construct gene regulatory networks116
Lung cancer gene therapy148
APTEC: aptamer-tethered enzyme capture as a novel rapid diagnostic test for malaria136
Inhibition of antiviral innate immunity by influenza virus NS1 protein49
Prognostic significance and therapeutic potential of eukaryotic translation initiation factor 5A (eIF5A) in hepatocellular carcinoma190
Dynamic Autophosphorylation of Mps1 Kinase Is Required for Faithful Mitotic Progression73
Development of novel viral promoter-driven DNA vectors for expression of shRNAs to mediate RNA interference in mammalian cells53
Genomic instability in laminopathy-based premature aging195
Association between angiotensin-converting enzyme and Alzheimer disease101
Ornithine decarboxylase from Tetrahymena thermophila: Purification, reversible modification and multiple forms93
Differential roles of RNA-binding proteins TRBP and PACT in RNA silencing and sensing67
A comparison of intravenous and intradiscal delivery of multipotential stem cells on the healing of injured intervertebral disk103
Developing vestibular neurons display differential commissural projection patterns with digestion of chondroitin sulfates63
A micropuncture and renal clearance study in the rat of the urinary excretion of heparin, chondroitin sulfate and metabolic breakdown products of connective tissue proteoglycans75
Heterogeneity of Neural Progenitor Cells in the Adult Mouse Spinal Cord61
O-032. the relationship of p85 and the apoptotic signaling of N-(4-hydroxyphenyl)retinamide (4HPR)81
Expression of chondroitin sulfotransferases in relation to cranial motor neuron movements in the embryonic hindbrain210
Plasticity of neural correlates for spatial navigation51
An Occludin-focal Adhesion Kinase Protein Complex At The Blood-testis Barrier: A Study Using The Cadmium Model51
Development of L-hydroxyamino acid dehydratase in rat liver169
Functional study of cerberus-like and noggin proteins: toward a biochemical understanding of BMP antagonists in skeletal disorders59
A study of urinary-type plasminogen activators in biological fluids173
Tyrosine kinase receptor immunoreactivity in trigeminal mesencephalic and motor neurons following transection of masseteric nerve of the rat114
Expression of the TRP2 allele of COL9A2 leads to alterations in the mechanical properties of human intervertebral discs65
Mechanical properties, bioactivity and corrosion resistance of oxygen and sodium plasma treated nickel titanium shape memory alloy116
Role of IHH signaling in the progression of joint formation in digit development51
Characteristics of phosphatidylinositol headgroup exchange in rat heart membranes60
Lithium attenuates the effects of dynorphin A(1-13) on inositol 1,4,5-trisphosphate and intracellular Ca2+ in rat ventricular myocytes84
Human T-cell leukemia virus type 1 oncoprotein Tax preferentially interacts with a group of cellular coiled-coil proteins60
Potential role of Atg16L1 in autophagic vesicle trafficking in primary cultured neurons31
Inositol phosphates: the elucidation of forms and functions58
Human Cis-regulatory Module Discovery by Genome Comparison68
Sox18 induces development of the lymphatic vasculature in mice157
Proteolytic cleavage of PDZD2 generates a secreted peptide containing two PDZ domains206
Sclerostin: a negative regulator of bone formation and a target for osteoporosis therapy223
Developing vestibular neurons display altered commissural projections with depletion of chondroitin sulfates of the hindbrain matrix69
Homologous pairing in duplex DNA regions and the formation of four-stranded paranemic joints promoted by RecA protein. Effects of GAP length and negative superhelicity74
Corrosion resistance, surface mechanical properties, and cytocompatibility of plasma immersion ion implantation-treated nickel-titanium shape memory alloys142
Heparan sulfates that upregulate regeneration of post-traumatic sciatic nerves of adult guinea pigs56
A Simple Novel Annular Puncture Model of Disc Degeneration in the Mouse Tail89
Regulatory role of neuronal proheparanase in synaptic function of the central vestibular system67
Intranasal vaccination of recombinant adeno-associated virus encoding receptor-binding domain of severe acute respiratory syndrome coronavirus (SARS-CoV) spike protein induces strong mucosal immune responses and provides long-term protection against SARS-CoV infection111
Identification of a novel RHO GTPase activating protein called DLC2, involved in hepatocellular carcinoma65
β-ionone suppresses mammary carcinogenesis, proliferative activity and induces apoptosis in the mammary gland of the Sprague-Dawley rat93
Oncogenicity of the developmental transcription factor Sox9144
The role of HOX genes in mouse inner ear development.62
Human COL2A1-directed SV40 T antigen expression in transgenic and chimeric mice results in abnormal skeletal development100
A tissue-specific exon of Myosin Va is responsible for selective cargo binding in melanocytes84
The chondrocytic journey in endochondral bone growth and skeletal dysplasia92
Association of lumbar disc degeneration with type IX collagen polymorphism in Chinese101
Thiol peroxidases mediate specific genome-wide regulation of gene expression in response to hydrogen peroxide99
Search for basonuclin target genes79
Degradation of lung proteoglycans by stimulated neutrophils67
Analysis of craniofacial defects caused by ectopic expression of Hoxb3.58
An aptamer-based piezoelectric crystal biosensor for SARS coronavirus helicase62
HP1α mediates defective heterochromatin repair and accelerates senescence in Zmpste24-deficient cells48
Answering a century old riddle: brachydactyly type A11368
Role of collagen X in fracture repair58
The engagement of glutamate and GABA receptors in central vestibular synapses for developmental acquisition of spatial recognition52
Mechanism of transdominant inhibition of CCR5-mediated HIV-1 infection by ccr5Δ3280
Transgenic mice expressing Cre-recombinase specifically in retinal rod bipolar neurons174
PDSS2 conditional knockout mouse model84
Impact of extracellular inorganic polyphosphate on osteoblast proliferation, differentiation and apoptosis60
Nerve guidance channel constructed by Schwann cell seeded aligned chitosan nanofiber97
Intervertebral disc cryopreservation110
Reconstitution Of Nucleus Pulposus Cell Matrix Niche In 3D Collagen Microsphere For MSC Discogenic Differentiation69
Pathogenesis of congenital cataract in a gamma-crystallin mutant mousemodel455
Reduced expression of AMPK-β1 during tumor progression enhances the oncogenic capacity of advanced ovarian cancer92
Cell death caused by single-stranded oligodeoxynucleotide-mediated targeted genomic sequence modification124
Human COL2A1-directed SV40 T-antigen expression in transgenic mice results in abnormal skeletal development76
Targeting the polyphosphate kinase 2 with aptamer-based inhibitors as an approach to Tuberculosis Therapy63
Regulation of heparanase gene expression and endoglucuronidase activity: Implication in cell invasion and metastasis62
Interleukin-8 is elevated in sera and sputum of patients with bronchiectasis55
Development of methods for the routine assay of mitochondrial aspartate amino-transferases in serum, and applications in the studyof human disease195
Vancouver prevalence of intervertebral disc degeneration: a MRI study of 769 volunteers76
p70 S6 kinase is a regulator of ovarian cancer metastasis via crosstalk between P-cadherin-beta1-integrin signaling axes70
Proheparanase-mediated AMPA-type glutamate receptor regulation in synaptic plasticity57
SUMOsp: A web server for sumoylation site prediction123
Shed syndecan-1 restricts neutrophil elastase from α1- antitrypsin in neutrophilic airway inflammation144
The role of genetics in pain59
A meta-analysis identifies adolescent idiopathic scoliosis association with LBX1 locus in multiple ethnic groups147
Characterization of the roles of yeast nuclear exosome cofactor TRAMP complex in pre-mRNA splicing257
Suppression of PACT-induced type I interferon production by herpes simplex virus 1 Us11 protein71
Mechanistic insight into chondrocyte adaptation to ER stress63
Circling, deafness, and yellow coat displayed by yellow submarine (Ysb) and light coat and circling (Lcc) mice with mutations on chromosome 3134
Postnatal developmental profile of otolith-related inferior olivary neurons in rats45
Development of three-dimesional system for culturing notochordal cells85
Absence of NUCKS augments paracrine effects of mesenchymal stem cells-mediated cardiac protection113
Susceptibility to myocardial ischemia reperfusion injury at early stage of type 1 diabetes in rats71
Aptamers against P. falciparum lactate dehydrogenase as a new approach to malaria diagnosis68
Osteoprotegerin (OPG) and interleukin-1 beta (il-1b) gene polymorphisms are associated with knee osteoarthritis in Chinese84
Quantitative characterization of mesenchymal cell aggregation process45
Functional Analyses of Type II Procollagen in Mouse Inner Ear Development43
The cloning and characterization of a beta-globin gene in the Sprague-Dawley rat186
Differential and overlapping expression of SOX2 and SOX9 in inner ear development48
Cell Repopulation of the Frozen Intervertebral Disc by Bone Marrow-derived Stromal Cells60
Stimulation of k-receptor in cultured heart myoblasts suppresses intracellular cAMP level and elevates intracellular Ca2+ through a pertussis-toxin-sensitive mechanism47
The role of calcium in the induction of ornithine decarboxylase by L-asparagine in Reuber H-35 rat hepatoma cells211
ChIP-array: gene regulation network construction from ChIP-seq/chip and mRNA expression data108
Type IIA Procollagen as a Modulator of Nodal Signaling49
Electrophoretic modification of sperm plasma membrane by ventral prostate secretion in golden hamsters67
Urinary polyanions important in urinary calcium oxalate crystallization197
The genetics of the degenerative intervertebral disc disease63
Modulation of synaptic plasticity by the partnership of proheparanase with peri-synaptic heparan sulfate proteoglycan and AMPA-type glutamate receptor65
Bioinformatics-aided discovery of transcriptional regulators of chondrocyte differentiation in the growth plate67
Molecular and cellular basis of synovial joint formation216
Global landscape of histone modifications contributes to cellular identity determination by affecting gene expression dynamics57
To understand the expression profile and function of heparanase in the adult spinal cord49
Expression of HoxB-3 in the anterior neural domains depends on other Hox genes57
Expression and three dimensional (3-D) X-ray structure of human glucose-6-phosphate dehydrogenase (G6PD) variants195
Proteomic identification and functional characterization of a novel ARF6 GTPase-activating protein, ACAP494
Differential patterns of developing vestibular commissural projection with digestion of chondroitin sulfates80
Regulation of FOXM1c by the Raf/MEK/MAPK pathway70
Abnormal chondrocyte differentiation in transgenic mice expression a Schmid metaphyseal chondrodysplasia Col10al mutation89
GWAS3D: detecting human regulatory variants by integrative analysis of genome-wide associations and chromosome states65
Crystal-suppressive modulators of separated urinary polyanions. In: H.-G. Tiselius (ED)81
Genetic and genomic analyses of chondrocyte adaptation to ER stress87
Molecular and cellular consequences of Indian hedgehog mutations causing brachydactylies118
Molecular studies of a glucose-6-phosphate dehydrogenase variant171
The involvement of replication in single stranded oligonucleotide-mediated gene repair108
Transferring receptor down-regulation in human leukemic HL-60 cells required prolonged treatment with phorbolesters and is associated with increases in AP-1 binding activity64
Differential regulation of retinoic acid signaling in adult spinal cord neural progenitors96
FaSD: a fast and accurate SNP detection algorithm for next-generation sequencing data76
The role of extracellular matrix in planarian regeneration46
The Over-expression of Bcl-2 antagonizes the pro-apoptotic function of the Kappa-Opioid receptor69
Kinesin-1 is involved in chondrocytes interaction with extracellular matrix65
The elav gene product of drosophila, required in neurons, has three rnp consensus motifs70
The prenatal expression of secretin receptor96
cSox3 expression and neurogenesis in the epibranchial placodes138
DNA aptamers as new therapeutic agents against sclerostin, ADAMTS-5 and WWP1 ubiquitin ligase28
Erratum: Proteomic identification and functional characterization of a novel ARF6 GTPase-activating protein, ACAP4 (Molecular and Cellular Proteomics (2006) vol. 5 (1437-1449))162
The Regulation of FGF Signaling by MT1-MMP in Calvarial Osteogenesis45
Potential signaling mechanisms of the secreted PDZ domain-containing protein 2 (sPDZD2) in tumor suppression61
Collagen XXII interacts with integrins via new motifs and links tenocytes to myocytes62
Study of transgenic mice ectopically expressing the mouse Hoxb-3 gene184
Strong antigenicity and neutralizing antibody induced by recombinant Recombinant adeno-associated virus expressing the receptor-binding domain of severe acute respiratory syndrome coronavirus S protein elicits protective neutralizing antibodies: implicati70
Identification of metal-binding proteins/Motifs in microorganisms by metalloproteome: an example for Bismuth63
SNPs of Fc-gamma receptor genes and chronic periodontitis109
Effects of charged amino-acid mutation on the solution structure of cytochrome b 5 and binding between cytochrome b 5 and cytochrome c111
cDNA cloning and characterization of the rat globin genes179
An insertional mutation affecting coat colour and vestibular function in mice45
Genome-wide Haplotype Association Mapping in mice identifies a genetic variant in CER1 associated with bone mineral density and fracture in southern Chinese women112
Inhibition of PACT mediated type 1 interferon production by herpes simplex virus type 1 Us11 protein271
In vivo study of asporin, a genetic risk factor for intervertebral disc degeneration80
miR-BART5 is an anti-apoptotic miRNA encoded by EBV and inhibits PUMA to promote host cell survival86
Genetic modifier(s) of embryonic lethality in type IIA procollagen deficient mice76
The double-stranded RNA-binding protein PACT activates cytoplasmic viral sensor MDA5 by promoting its oligomerization53
Wound healing in membrane-type-1 matrix metalloproteinase-deficient mice [1]73
Adenoviral delivery of RNA decoys restores cellular proapoptotic protein PUMA expression by silencing Epstein-Barr virus-encoded miR-BART5 in nasopharyngeal carcinoma cells57
Role of heparanase in synaptic plasticity at the hippocampus and the vestibular nucleus65
Alkaloids of the medicinal plant Melodinus suaveolens (Apocynaceae): an inquiry into their actions in mammalianand microbial systems.309
The double-stranded RNA-binding protein PACT is a cellular activator of MDA5 in innate antiviral immune response58
Interactions of bismuth with proteins and enzymes: insight into its mechanism of action68
Anti-ganglioside antibodies were not detected in human subjects infected with or vaccinated against 2009 pandemic influenza A (H1N1) virus154
Histidine-rich protein, HPN and metallothionein: are they similar?64
Association between CLU Polymorphisms and clinical phenotypes in Alzheimer’s Disease67
Lectin - carbohydrate interactions in lympho-haemopoiesis: a study of L-selectin, ligands of L-selectin and CD24 inthe rat164
Crosslinkers and Motors Organize Dynamic Microtubules to Form Stable Bipolar Arrays in Fission Yeast82
Genetic risk factors for intervertebral disc degeneration79
Examination of seroprevalence of coronavirus HKU1 infection with S protein-based ELISA and neutralization assay against viral spike pseudotyped virus89
Hoxb3 mutation leads to interleukin-6 dependent plasmacytoma320
The role of Sox 10 on survival and proliferation of enteric neural crest stem cells64
An H5N1-based matrix protein 2 ectodomain tetrameric peptide vaccine provides cross-protection against lethal infection with H7N9 influenza virus174
Matrix remodeling during intervertebral disc growth and degeneration detected by multichromatic fast staining119
When MT1-MMP meets ADAMs158
Postnatal maturation of the vestibular circuit for gravity detection by under the regulation of perineuronal chondroitin sulfates and semaphorin 3A52
In Vivo Analysis of Specificity of Target Gene Transactivation by SOX960
In vivo cellular adaptation to ER stress: Survival strategies with double-edged consequences113
Structure and hemimethylated CpG binding of the SRA domain from human UHRF1123
Yin yang 1 directly regulates the transcription of RE-1 silencing transcription factor78
Epigenetic dysregulation of leukaemic HOX code in MLL-rearranged leukaemia mouse model149
The phosphatase-transcription activator EYA1 is targeted by anaphase-promoting complex/Cdh1 for degradation at M-to-G1 transition77
The role of Pax6 in beta-amyloid-induced neuronal apoptosis49
Hoxb1 cooperates with Gli to activate Nkx2.2 expression in the neurogenesis of mammalian hindbrain rhombomere 458
Intracellular transportation in diseases and development60
Collagen composition of normal and myxomatous human mitral heart valves89
Alteration of gene expression with antisense oligonucleotides in whole embryo culture85
A founder mutation in presenilin 1 causing early-onset Alzheimer disease in unrelated Caribbean Hispanic families83
k-opioid receptor agonist inhibits the cholera toxin sensitive G-protein in the heart122
Influenza A virus NS1 protein suppresses innate antiviral immune response by preventing PACT-induced activation of RIG-I51
Genome-wide association study identifies a susceptibility locus for biliary atresia on 10q24.2251
Chondroitinase ABC-I and -II linked chitosan microbeads increase neurtire length in CSPG-enriched astrocyte culture63
Interaction of collagen α1(X) containing engineered NC1 mutations with normal α1(X) in vitro. Implications for the molecular basis of Schmid metaphyseal chondrodysplasia65
Localization of nerve growth factor, neurotrophin-3, and glial cell line-derived neurotrophic factor in nestin-expressing reactive astrocytes in the caudate-putamen of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated C57/B1 mice107
The mouse neurological mutant flailer expresses a novel hybrid gene derived by exon shuffling between Gnb5 and Myo5a110
Purification and charaterization of a physiological substrate of PKJ in central nervous system myelin51
Antiviral activity of cGAMP against RNA virus infection44
NdPASA: A novel pairwise protein sequence alignment algorithm that incorporates neighbor-dependent amino acid propensities87
The antidiabetic effects of a dry powder of dietary vegetable and fruit mixtures in diabetic db/db mice99
Correlation between the Compressive Macro-mechanical Properties of the Human Nucleus Pulposus and the Nano Structure of its Individual Collagen Fibrils52


TotJulAugSepOctNovDecJanFebMarAprMayJun
2014/2015333455669224115311849240510040191415682655135311201000
2015/2016980811217923419015119145997420702240108281189301610009
2016/201757219628730403828588499663092340321303811410274904186
2017/201842812336934721954433222087691199721915184360435603250
2018/2019748297939229655762313660881695185817733085585112398434
2019/202033570910357691704496528015124410400000
Ever339856