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Article: Production of influenza pseudotyped lentiviral particles and their use influenza research and diagnosis: an update

TitleProduction of influenza pseudotyped lentiviral particles and their use influenza research and diagnosis: an update
Authors
Garcia, JLai, JCC
Keywordscharacterization
diagnostics
influenza
neutralization assay
production
pseudoparticles
pseudotyped lentiviral particle
Issue Date2011
PublisherExpert Reviews Ltd. The Journal's web site is located at http://www.future-drugs.com/publication.asp?publicationid=7
Citation
Expert Review of Anti-Infective Therapy, 2011, v. 9 n. 4, p. 443-455 How to Cite?
DOI: http://dx.doi.org/10.1586/eri.11.25
AbstractPseudotyped viral particles are being used as safe surrogates to mimic the structure and surface of many viruses, including highly pathogenic viruses such as avian influenza H5N1, to investigate biological functions mediated by the envelope proteins derived from these viruses. The first part of this article evaluates and discusses the differences in the production and characterization of influenza pseudoparticles. The second part focuses on the applications that such a flexible tool can provide in modern influenza research, in particular in the fields of drug discovery, molecular biology and diagnosis.
Persistent Identifierhttp://hdl.handle.net/10722/140759
ISSN
1478-7210
2021 Impact Factor: 5.854
2020 SCImago Journal Rankings: 1.211
ISI Accession Number ID
WOS:000290839700015
Funding AgencyGrant Number
University Grants Committee of the Hong Kong Special Administrative Region, ChinaAoE/M-12/06
Research Grants Council of Hong KongHKU774109M
French Ministry of Health, RESPARI Pasteur Network
Li Ka Shing Foundation
Funding Information:

This work was supported by the University Grants Committee of the Hong Kong Special Administrative Region, China (Project No: AoE/M-12/06), the Research Grants Council of Hong Kong (HKU774109M), the French Ministry of Health, RESPARI Pasteur Network and the Li Ka Shing Foundation. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.

Grants
Control of Pandemic and Inter-pandemic Influenza

 

DC FieldValueLanguage
dc.contributor.authorGarcia, Jen_US
dc.contributor.authorLai, JCCen_US
dc.date.accessioned2011-09-23T06:18:26Z-
dc.date.available2011-09-23T06:18:26Z-
dc.date.issued2011en_US
dc.identifier.citationExpert Review of Anti-Infective Therapy, 2011, v. 9 n. 4, p. 443-455en_US
dc.identifier.issn1478-7210-
dc.identifier.urihttp://hdl.handle.net/10722/140759-
dc.description.abstractPseudotyped viral particles are being used as safe surrogates to mimic the structure and surface of many viruses, including highly pathogenic viruses such as avian influenza H5N1, to investigate biological functions mediated by the envelope proteins derived from these viruses. The first part of this article evaluates and discusses the differences in the production and characterization of influenza pseudoparticles. The second part focuses on the applications that such a flexible tool can provide in modern influenza research, in particular in the fields of drug discovery, molecular biology and diagnosis.-
dc.languageengen_US
dc.publisherExpert Reviews Ltd. The Journal's web site is located at http://www.future-drugs.com/publication.asp?publicationid=7-
dc.relation.ispartofExpert Review of Anti-Infective Therapyen_US
dc.subjectcharacterization-
dc.subjectdiagnostics-
dc.subjectinfluenza-
dc.subjectneutralization assay-
dc.subjectproduction-
dc.subjectpseudoparticles-
dc.subjectpseudotyped lentiviral particle-
dc.subject.meshInfluenzavirus A - physiology-
dc.subject.meshLentivirus - genetics - metabolism-
dc.subject.meshMembrane Glycoproteins - genetics - metabolism-
dc.subject.meshOrthomyxoviridae Infections - diagnosis - virology-
dc.subject.meshViral Proteins - metabolism-
dc.titleProduction of influenza pseudotyped lentiviral particles and their use influenza research and diagnosis: an updateen_US
dc.typeArticleen_US
dc.identifier.emailGarcia, J: jmgarcia@hku.hken_US
dc.identifier.emailLai, JCC: jimmylai@hkucc.hku.hken_US
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1586/eri.11.25-
dc.identifier.pmid21504401-
dc.identifier.scopuseid_2-s2.0-79955085527-
dc.identifier.hkuros194077en_US
dc.identifier.volume9en_US
dc.identifier.issue4-
dc.identifier.spage443en_US
dc.identifier.epage455en_US
dc.identifier.isiWOS:000290839700015-
dc.publisher.placeUnited Kingdom-
dc.relation.projectControl of Pandemic and Inter-pandemic Influenza-
dc.identifier.citeulike9196789-
dc.identifier.issnl1478-7210-

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