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- Publisher Website: 10.1007/s00330-002-1535-7
- Scopus: eid_2-s2.0-0038343515
- PMID: 12594554
- WOS: WOS:000181688200011
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Article: Computed tomography characteristics of advanced primary pulmonary lymphoepithelioma-like carcinoma
Title | Computed tomography characteristics of advanced primary pulmonary lymphoepithelioma-like carcinoma |
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Authors | |
Keywords | Computed tomography Lung cancer Lymphoepithelioma-like carcinoma |
Issue Date | 2003 |
Publisher | Springer Verlag. The Journal's web site is located at http://link.springer.de/link/service/journals/00330/index.htm |
Citation | European Radiology, 2003, v. 13 n. 3, p. 522-526 How to Cite? |
Abstract | Our objectives were to document CT features of advanced primary pulmonary lymphoepithelioma-like carcinoma (LELC) and to determine features that may assist differentiation from other non-small cell lung cancers (NSCLC). Imaging and clinical data of all patients with biopsy-proven pulmonary LELC (n=12) were retrieved from a database of all NSCLC patients over a 2-year period. Twenty-five controls were recruited from other inoperable non-LELC NSCLC patients from the database. Pre-treatment CT scans of the thorax of both study and control patients were reviewed for lobe involved; tumour site, borders and size; and pleural, vascular of pulmonary involvement. Presence of lymphangitis carcinomatosis was noted. Lymph node metastasis was characterised as ipsilateral or contralateral enlarged (>1 cm) mediastinal or hilar nodes, or as peribronchovascular nodal spread. Differences between the two groups were tested using Mann-Whitney rank-sum test. The LELC tumours were significantly larger (45.67 vs 17.71 cm 2) than controls and were closely associated with the mediastinum. There were more LELC tumours with well-defined borders (p<0.001) and fewer with spiculated borders (p<0001) than non-LELC tumours. There was increased peribronchovascular nodal spread (p=0.01) and vascular encasement (p=0.02) in LELC compared with non-LELC tumours. Advanced primary pulmonary LELC has distinct radiological features, and can appear as well-defined tumour closely associated with the mediastinum, with peribronchovascular spread and vascular encasement. |
Persistent Identifier | http://hdl.handle.net/10722/148340 |
ISSN | 2023 Impact Factor: 4.7 2023 SCImago Journal Rankings: 1.656 |
ISI Accession Number ID | |
References |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Ooi, GC | en_HK |
dc.contributor.author | Ho, JCM | en_HK |
dc.contributor.author | Khong, PL | en_HK |
dc.contributor.author | Wong, MP | en_HK |
dc.contributor.author | Lam, WK | en_HK |
dc.contributor.author | Tsang, KWT | en_HK |
dc.date.accessioned | 2012-05-29T06:12:20Z | - |
dc.date.available | 2012-05-29T06:12:20Z | - |
dc.date.issued | 2003 | en_HK |
dc.identifier.citation | European Radiology, 2003, v. 13 n. 3, p. 522-526 | en_HK |
dc.identifier.issn | 0938-7994 | en_HK |
dc.identifier.uri | http://hdl.handle.net/10722/148340 | - |
dc.description.abstract | Our objectives were to document CT features of advanced primary pulmonary lymphoepithelioma-like carcinoma (LELC) and to determine features that may assist differentiation from other non-small cell lung cancers (NSCLC). Imaging and clinical data of all patients with biopsy-proven pulmonary LELC (n=12) were retrieved from a database of all NSCLC patients over a 2-year period. Twenty-five controls were recruited from other inoperable non-LELC NSCLC patients from the database. Pre-treatment CT scans of the thorax of both study and control patients were reviewed for lobe involved; tumour site, borders and size; and pleural, vascular of pulmonary involvement. Presence of lymphangitis carcinomatosis was noted. Lymph node metastasis was characterised as ipsilateral or contralateral enlarged (>1 cm) mediastinal or hilar nodes, or as peribronchovascular nodal spread. Differences between the two groups were tested using Mann-Whitney rank-sum test. The LELC tumours were significantly larger (45.67 vs 17.71 cm 2) than controls and were closely associated with the mediastinum. There were more LELC tumours with well-defined borders (p<0.001) and fewer with spiculated borders (p<0001) than non-LELC tumours. There was increased peribronchovascular nodal spread (p=0.01) and vascular encasement (p=0.02) in LELC compared with non-LELC tumours. Advanced primary pulmonary LELC has distinct radiological features, and can appear as well-defined tumour closely associated with the mediastinum, with peribronchovascular spread and vascular encasement. | en_HK |
dc.language | eng | en_US |
dc.publisher | Springer Verlag. The Journal's web site is located at http://link.springer.de/link/service/journals/00330/index.htm | en_HK |
dc.relation.ispartof | European Radiology | en_HK |
dc.subject | Computed tomography | en_HK |
dc.subject | Lung cancer | en_HK |
dc.subject | Lymphoepithelioma-like carcinoma | en_HK |
dc.subject.mesh | Carcinoma - pathology - radiography - virology | - |
dc.subject.mesh | Carcinoma, Non-Small-Cell Lung - pathology - radiography | - |
dc.subject.mesh | Epstein-Barr Virus Infections - complications | - |
dc.subject.mesh | Lung Neoplasms - pathology - radiography - virology | - |
dc.subject.mesh | Tomography, X-Ray Computed - methods | - |
dc.title | Computed tomography characteristics of advanced primary pulmonary lymphoepithelioma-like carcinoma | en_HK |
dc.type | Article | en_HK |
dc.identifier.email | Ooi, GC: cgcooi@hkucc.hku.hk | en_HK |
dc.identifier.email | Ho, JCM:jhocm@hku.hk | en_HK |
dc.identifier.email | Khong, PL: plkhong@hkucc.hku.hk | en_HK |
dc.identifier.email | Wong, MP: mwpik@hkucc.hku.hk | - |
dc.identifier.email | Lam, WK: lamwk@hku.hk | - |
dc.identifier.email | Tsang, KWT: kwttsang@hku.hk | - |
dc.identifier.authority | Ho, JCM=rp00258 | en_HK |
dc.identifier.authority | Khong, PL=rp00467 | en_HK |
dc.identifier.authority | Wong, MP=rp00348 | en_HK |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.doi | 10.1007/s00330-002-1535-7 | - |
dc.identifier.pmid | 12594554 | - |
dc.identifier.scopus | eid_2-s2.0-0038343515 | en_HK |
dc.identifier.hkuros | 81007 | - |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-0038343515&selection=ref&src=s&origin=recordpage | en_HK |
dc.identifier.volume | 13 | en_HK |
dc.identifier.issue | 3 | en_HK |
dc.identifier.spage | 522 | en_HK |
dc.identifier.epage | 526 | en_HK |
dc.identifier.isi | WOS:000181688200011 | - |
dc.publisher.place | Germany | en_HK |
dc.identifier.scopusauthorid | Ooi, GC=7006176119 | en_HK |
dc.identifier.scopusauthorid | Ho, JCM=7402649981 | en_HK |
dc.identifier.scopusauthorid | Khong, PL=7006693233 | en_HK |
dc.identifier.scopusauthorid | Wong, MP=7403907887 | en_HK |
dc.identifier.scopusauthorid | Lam, WK=7203021937 | en_HK |
dc.identifier.scopusauthorid | Tsang, KWT=7201555024 | en_HK |
dc.customcontrol.immutable | sml 130620 | - |
dc.identifier.issnl | 0938-7994 | - |