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Conference Paper: Platelet function in patients with hypercholesterolaemia

TitlePlatelet function in patients with hypercholesterolaemia
Authors
Betteridge, DJCooper, MBSaggerson, EDPrichard, BNCTan, KCBLing, EBarbera, GMccarthy, SSmith, CCT
KeywordsAdenosine
calcium
familial hypercholesterolaemia
inositol 1,4,5 trisphosphate
noradrenaline
platelets
Issue Date1994
Citation
European Journal Of Clinical Investigation, Supplement, 1994, v. 24 n. 1, p. 30-33 How to Cite?
DOI: http://dx.doi.org/10.1111/j.1365-2362.1994.tb02423.x
AbstractPlatelets and plasma lipoproteins, particularly low density lipoprotein, have important roles in atherogenesis. Evidence from several sources suggests that important interactions occur between these individual components of the atherogeneic process. Here we review work from our own laboratory on platelet function in normal individuals and patients heterozygous for familial hypercholesterolaemia (FH). Data is presented on the role of platelet noradrenaline and also on altered cellular signalling in platelets from FH individuals who have plasma low density lipoprotein concentrations which are approximately double those seen in normal subjects.
Persistent Identifierhttp://hdl.handle.net/10722/163540
ISSN
0960-135X
ISI Accession Number ID
WOS:A1994MY18300007

 

DC FieldValueLanguage
dc.contributor.authorBetteridge, DJen_US
dc.contributor.authorCooper, MBen_US
dc.contributor.authorSaggerson, EDen_US
dc.contributor.authorPrichard, BNCen_US
dc.contributor.authorTan, KCBen_US
dc.contributor.authorLing, Een_US
dc.contributor.authorBarbera, Gen_US
dc.contributor.authorMccarthy, Sen_US
dc.contributor.authorSmith, CCTen_US
dc.date.accessioned2012-09-05T05:37:13Z-
dc.date.available2012-09-05T05:37:13Z-
dc.date.issued1994en_US
dc.identifier.citationEuropean Journal Of Clinical Investigation, Supplement, 1994, v. 24 n. 1, p. 30-33en_US
dc.identifier.issn0960-135Xen_US
dc.identifier.urihttp://hdl.handle.net/10722/163540-
dc.description.abstractPlatelets and plasma lipoproteins, particularly low density lipoprotein, have important roles in atherogenesis. Evidence from several sources suggests that important interactions occur between these individual components of the atherogeneic process. Here we review work from our own laboratory on platelet function in normal individuals and patients heterozygous for familial hypercholesterolaemia (FH). Data is presented on the role of platelet noradrenaline and also on altered cellular signalling in platelets from FH individuals who have plasma low density lipoprotein concentrations which are approximately double those seen in normal subjects.en_US
dc.languageengen_US
dc.relation.ispartofEuropean Journal of Clinical Investigation, Supplementen_US
dc.subjectAdenosine-
dc.subjectcalcium-
dc.subjectfamilial hypercholesterolaemia-
dc.subjectinositol 1,4,5 trisphosphate-
dc.subjectnoradrenaline-
dc.subjectplatelets-
dc.subject.meshBlood Platelets - Chemistry - Physiologyen_US
dc.subject.meshCatecholamines - Analysisen_US
dc.subject.meshHumansen_US
dc.subject.meshHyperlipoproteinemia Type Ii - Metabolismen_US
dc.subject.meshPlatelet Activation - Physiologyen_US
dc.subject.meshSignal Transductionen_US
dc.titlePlatelet function in patients with hypercholesterolaemiaen_US
dc.typeConference_Paperen_US
dc.identifier.emailTan, KCB:kcbtan@hku.hken_US
dc.identifier.authorityTan, KCB=rp00402en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1111/j.1365-2362.1994.tb02423.x-
dc.identifier.pmid8013529-
dc.identifier.scopuseid_2-s2.0-0028357476en_US
dc.identifier.volume24en_US
dc.identifier.issue1en_US
dc.identifier.spage30en_US
dc.identifier.epage33en_US
dc.identifier.isiWOS:A1994MY18300007-
dc.publisher.placeUnited Kingdomen_US
dc.identifier.scopusauthoridBetteridge, DJ=34973752700en_US
dc.identifier.scopusauthoridCooper, MB=7404410514en_US
dc.identifier.scopusauthoridSaggerson, ED=7006639728en_US
dc.identifier.scopusauthoridPrichard, BNC=7006824098en_US
dc.identifier.scopusauthoridTan, KCB=8082703100en_US
dc.identifier.scopusauthoridLing, E=36785464000en_US
dc.identifier.scopusauthoridBarbera, G=7004649462en_US
dc.identifier.scopusauthoridMcCarthy, S=7202136093en_US
dc.identifier.scopusauthoridSmith, CCT=8082489800en_US
dc.identifier.issnl0960-135X-

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